• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Please personalize this letter by updating the underlined items
Please personalize this letter by updating the underlined items

... seem to offer cost savings to the employer or plan sponsor, there are a number of other factors that also must be considered. For example, there very well may not be a CVS retail store that is convenient to all plan beneficiaries, and mail order is not a viable option for all medications. Some lette ...
Pharmaceutical Preparations for External Use
Pharmaceutical Preparations for External Use

... C-penicillin v is given orally. D-procaine penicillin is given IM. E- Piparacillin is an anti pseudomonal drug. ...
BRCA Founder Mutations
BRCA Founder Mutations

... •Predictive statistical models using family history have been developed primarily with data from white families & may not be applicable to diverse populations •Models are based upon accurate estimates of population- specific prevalence of high-risk genotypes – data not available for most minority po ...
White Paper: DMET™ Plus allele translation
White Paper: DMET™ Plus allele translation

... approximately 30 percent of candidates fail.4 This attrition is primarily due to poor pharmacokinetics and toxicity, two risks that can be strongly influenced by genetically determined variation. Thus, pharmaceutical companies are actively reevaluating strategies used during drug discovery and devel ...
here - Norwegian Genomics Consortium
here - Norwegian Genomics Consortium

... depending on the type of analysis (Table 1). All common variants described in databases such as dbSNP and our in-house database were filtered out, as well as synonymous variants (not causing amino acid change) and variants in introns and UTR regions except for those affecting canonical splice sites. ...
Aminoglycosides
Aminoglycosides

... Staph aureus *)  Lack activity against most anaerobic or facultative bacteria and activity against G+ve# organisms is limited * in combination # Strept pyogenes is highly resistant ...
Ensemble Therapeutics Presents Oral Efficacy of First-in
Ensemble Therapeutics Presents Oral Efficacy of First-in

...  The IL-17A inhibitors were active in vivo in murine models of acute inflammation when injected intraperitoneally (into the body cavity) or by oral gavage (feeding tube). ...
Genomics
Genomics

...  The main difference between genomics and genetics is that genetics scrutinizes the functioning and composition of the single gene where as genomics addresses all genes and their inter relationships in order to identify their combined influence on the growth and development of the organism. ...
Document
Document

... Genes that are adjacent and close to each other on the same chromosome tend to move as a unit; the probability that they will segregate as a unit is a function of the distance between them. ...
Extending Mendel Student Notes
Extending Mendel Student Notes

... on the same chromosome tend to move as a unit; the probability that they will segregate as a unit is a function of the distance between them. ...
Combating substance abuse: A review of therapeutic management
Combating substance abuse: A review of therapeutic management

... • Controlled substances in schedule II to IV • Data transmitted to the department within 7 days of dispensing • All data is confidential and may only be released:  To the patient (over the age of 18) if requested  To a prescriber or dispenser who has a direct patient care relationship  If the inf ...
Anticonvulsants
Anticonvulsants

... c. Initially carbamazepine has a low systemic clearance, however over time the clearance increases requiring an increase in dose <= d. She was not loaded with carbamazepine appropriately e. All of the above 9. Your patient has abnormal LFTs, in particular an elevated AST. He tells you he is on medic ...
Regional Anesthesia for Veterinary Dentistry
Regional Anesthesia for Veterinary Dentistry

... called “wind up” which can produce alterations in the way that the patient responds to even the gentlest touch during recovery from a procedure eliciting this over-stimulation of the Central Nervous System (CNS).4 This response is termed allodynia and is something that we can and should prevent in o ...
OAB Conversation Starters
OAB Conversation Starters

... Toviaz should be taken with liquid and swallowed whole. Toviaz can be administered with or without food, and should not be chewed, divided, or crushed. (2) --------------------------------------DOSAGE FORMS AND STRENGTHS--------------------------------------Toviaz 4 mg extended-release tablets are l ...
Treatment of Tuberculosis
Treatment of Tuberculosis

... • 20-65% of SAT are nonadherent • Enhanced DOT • Comprehensive patient centered strategy of fully supervised DOT with multiple incentives and enablers • Enablers- remove barriers to Treatment ...
January 2015 Monitoring International Trends
January 2015 Monitoring International Trends

... adherence to iron chelation therapy (ICT), which is used to manage iron overload in patients who have repeat transfusions2. A second study provided evidence that blood transfusion improves health-related quality of life for children with SCD3. ...
| What is new about Rio? Rogerio Souza and Steven M. Kawut
| What is new about Rio? Rogerio Souza and Steven M. Kawut

... however, it is difficult to make a similar claim in the PATENT-2 or CHEST-2 studies, due to the lack of formal statistical testing and the forces of selection in the sample of patients who enter extension studies. For example, patients assigned to active treatment or placebo with clinical worsening ...
Genetics and Intelligence - Yale School of Medicine
Genetics and Intelligence - Yale School of Medicine

... that is associated with verbal ability, the gene would also be expected to be associated with spatial abilit y and other specific cognitive abilities. This finding is surprising because it goes against the tide of the popular modular theory of cognitive neuroscience that assumes that cognitive proce ...
Option D past paper questions 1. Aspirin, paracetamol
Option D past paper questions 1. Aspirin, paracetamol

... small doses. Other than the possibility of death, outline the problems associated with taking larger doses of paracetamol. [2] (d) State one important use for aspirin other than the relief of pain and fever. [1] (e) Other than the phenyl group, state the name of one other functional group that is co ...
File - the Drug Card Database
File - the Drug Card Database

... Pts who have asthma, allergies, and nasal polyps or who are allergic to tartrazine are at an ↑ risk for developing hypersensitivity reactions. Assess pain and limitation of movement; note type, location, an intensity before and at the peak after administration. Lab Considerations: Monitor hepatic fu ...
Présentation PowerPoint - International Dose
Présentation PowerPoint - International Dose

... Hormesis [Biological Effects of Low Level Exposure, (B.E.L.L.E.)] and Dermatology (cont’d) Low-dose toxicology and pharmacology will not only provide a significant research challenge but should also contribute to better methods for lowdose risk assessment for complex mixtures of chemical compounds. ...
**** 1 - unist
**** 1 - unist

... is completely independent of classical receptor transcriptional agonism. Similarly, inhibition of PPARg phosphorylation in obese patients by rosiglitazone is very tightly associated with the antidiabetic effects of this drug. More recently, we have developed novel synthetic compounds that have a uni ...
Drug Testing 2016 - Governor`s Institute on Substance Abuse
Drug Testing 2016 - Governor`s Institute on Substance Abuse

... • The result does not tell you the route, time of, or amount of ingestion. ...
Complications to the relationship between genotype to phenotype
Complications to the relationship between genotype to phenotype

... Complications to the relationship between genotype to phenotype Commentary written in response to the release of the first draft of the human genome sequence From Science Compass August 3, 2001 ...
February Newsletter - Portland Dental Anesthesia
February Newsletter - Portland Dental Anesthesia

... One key point with oral sedation is the fact that each drug has a dose response curve and as the dose increases the level of sedation and possible side effects also increase. There are always those who are hyper and hypo responders. Oral sedation effects are somewhat unpredictable because the dose c ...
< 1 ... 914 915 916 917 918 919 920 921 922 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report