• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload


... Infections caused by bacteria belonging to the Mycobacterium avium complex (MAC) are increasingly recognized as clinically important. MAC is, after M. tuberculosis, the most common cause of mycobacterial pulmonary disease. In addition, severe MAC infections are common in patients with acquired immun ...
PARADE: Audit Tool and Intervention Guidance
PARADE: Audit Tool and Intervention Guidance

...  Documentation of rationale for intended medication discrepancies  Incidence of unintended medication discrepancies  You will audit 5-10 medical records of patients discharged from your facility on any anticoagulant who have been re-hospitalized within the past 30 days (if there are no re-hospita ...
Morphine-induced Myoclonus in a Patient with End
Morphine-induced Myoclonus in a Patient with End

... of symptoms, likely because direct injection of morphine into the cerebrospinal fluid bypasses hepatic metabolism and generation of M3G.5 One approach to the treatment of neuroexcitatory side effects is opioid rotation, in which one opioid is switched to another in order to diminish toxicity of spec ...
Script Notes - AmeriHealth Caritas Pennsylvania
Script Notes - AmeriHealth Caritas Pennsylvania

... increase of stroke, heart attack and death in subjects who were prescribed testosterone. Another study found the risk of heart attack doubled in men over age 65 in the first 90 days after filling a testosterone product prescription. For men below age 65 who also had a pre-existing history of cardiac ...
1. (U4C3L1:Q1) Study the table and indicate t
1. (U4C3L1:Q1) Study the table and indicate t

... What should you tell her first? A) "Residential treatment centers because they provide support and experience from other drug abusers who are also at the center." B) "Cold turkey because you stop taking drugs immediately." C) "Detoxification centers because health care professionals help you quit th ...
Population Genetics
Population Genetics

... a. Analysis of Drosphilia enzymes indicates have at least 30% of gene loci with multiple alleles. b. Similar results with other species indicates that allele variation is the rule in natural populations. – Gene mutations provide new alleles, and therefore are the ultimate source of variation. a. A g ...
Genetics – the study of how traits are passed from parents to offspring.
Genetics – the study of how traits are passed from parents to offspring.

... These traits are the characteristics that make an organism what it is. Traits can be for: ...
No significant differences were found between the two groups in
No significant differences were found between the two groups in

... are compared with similar patients receiving a different treatment-usually an inactive substance (placebo), or a different drug. • Randomized-subjects are randomly allocated to receive one or other of the alternative treatments under study (like tossing a coin) • Blinded - both tester and subject ar ...
February 26, 2015 Meeting Summary - Posted 03/10/2015, Updated 03/18/2015
February 26, 2015 Meeting Summary - Posted 03/10/2015, Updated 03/18/2015

... recently approved product Viekira Pak (ombitasvir/paritaprevir/ritonavir and dasabuvir tablets). Chronic hepatitis C information was reviewed focusing on its prevalence, disease progression, and treatment goals. A treatment regimen flowchart was presented which highlighted the different pathways to ...
Snow, skunk and psychonauts
Snow, skunk and psychonauts

... Cannabis use, even before an upsurge of media attention around its effects on the mental health of users, has been steadily decreasing over the last ten years. Although the number of people drinking alcohol has reduced, crucially those who are drinking are drinking to more dangerous levels. In March ...
Pharmaceutical Regulatory and Compliance Congress and Best
Pharmaceutical Regulatory and Compliance Congress and Best

... million not to produce the generic equivalent drug of Cardizem CD. As a result, consumers paid nearly double the price for Cardizem CD, one of the most effective heart medications on the market. For a month’s dose, the brand name drug cost $73.00 and the generic form cost $32.00. In January 2003, th ...
HoFH text summary
HoFH text summary

... approved PCSK inhibitors, work through increasing the levels of LDLR and therefore do not work all that effectively in patients with HoFH in whom LDLRs are markedly impaired or absent. Two other medications approved for HoFH reduce LDL-C by a mechanism separate from the LDLR, but can increase fat i ...
Genetics
Genetics

... • Most X-linked traits are caused by a recessive allele located on the X-Chromosome. Because Y chromosomes do not have all the genes found on an X chromosome, men are less likely to have the dominant normal gene that would prevent the condition. Therefore, X-linked traits are several times more like ...
Opioid Safety in Patients With Renal or Hepatic Dysfunction
Opioid Safety in Patients With Renal or Hepatic Dysfunction

... parent compounds to active or inactive metabolites. In patients with liver failure, reduced metabolism usually results in accumulation of the parent drug in the body with repeated administration. In general, patients with severe liver disease should be prescribed lower doses of opioids, with extende ...
Protocol - Medicines Management
Protocol - Medicines Management

... there are exceptional circumstances. Treatment discontinuation must be confirmed by letter from the GP to the hospital clinician and patient and/or carer. Primary Care monitoring Once the patient has been accepted by their primary care provider the responsibility for re-prescribing the drug and furt ...
Psychiatric Medication - integratedservice.org
Psychiatric Medication - integratedservice.org

... • Anti-depressant drugs increase synaptic levels of serotonin • Anti-anxiety drugs increase effectiveness of GABA or increase serotonin ...
Application of Molecular Technologies in Beef Production
Application of Molecular Technologies in Beef Production

... • The various possible forms of a gene are called alleles • When an individual has two identical alleles for the same trait, they are homozygous (AA, bb, etc.) • When an individual has two contrasting alleles for the same trait, they are heterozygous (Aa, Bb, etc.) ...
Other Genetic Crosses
Other Genetic Crosses

... Multiple Alleles ...
Warfarin Administration Guidelines
Warfarin Administration Guidelines

... In elderly patients or patients who are debilitated, are malnourished, have congestive heart failure, have liver disease, have had recent major surgery, or are taking medications known to increase sensitivity to warfarin (e.g., amiodarone), consider using a starting dose of < 5 mg with subsequent do ...
Methadone - Community Pharmacy | Home
Methadone - Community Pharmacy | Home

... A treatment plan will be determined for each patient during the first month of treatment and reviewed on a three monthly basis. The keyworker should contact the community pharmacist to inform the progress review and treatment plan every three ...
DRUG INTERACTIONS WITH TUBERCULOSIS THERAPY
DRUG INTERACTIONS WITH TUBERCULOSIS THERAPY

... and predicting drug interactions Cytochrome P450 is a large family of related isoenzymes of which about 30 have been identified. The most frequently involved in drug interactions are CYP3A4 and CYP2D6. There are many drugs that are metabolised by these cytochrome P450 isoenzymes. Drugs may be metabo ...
FY M.Pharm Medicinal Natural Products
FY M.Pharm Medicinal Natural Products

... Study of cell penetrating peptides and fusogenic peptides and their applications in drug delivery 3. Drug Membrane interactions  Possible effects of drugs on the membranes & effect of membrane on drugs  Role of drug membrane interaction in pharmacokinetics & pharmacodynamics of drugs  Development ...
7-2.6 Standard Notes
7-2.6 Standard Notes

... It is essential for students to know that offspring inherit the genes for particular traits from their parents.  Genes for a particular trait normally come in pairs.  Since each parent normally has two alleles for a single trait, we use a Punnett square to determine the possibilities of the combin ...
• 1-How are sex-linked genes expressed differently in males and
• 1-How are sex-linked genes expressed differently in males and

... • 2- How would you determine whether a trait is sex-linked by observing the offspring of several genetic crosses? ...
Long-acting inhaled bronchodilators in COPD: how many drugs do we need? EDITORIAL
Long-acting inhaled bronchodilators in COPD: how many drugs do we need? EDITORIAL

... salbutamol during treatment with the combination compared with the individual components, but this was the only clinically important comparator included in this study. The present data are interesting although largely limited to spirometric outcomes and represent an unusual dosing regime for clinica ...
< 1 ... 921 922 923 924 925 926 927 928 929 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report