Download 02 66862244 Fax: 02 66862257 Email: sales@custommedi

Complementary Compounding Services
1/130 Tamar St, Ballina, NSW, 2478
Ph: 02 66862244 Fax: 02 66862257
Email: [email protected]
FIRST LINE TREATMENT PROTOCOL FOR BLASTOCYSTIS HOMINIS INFECTION
WITH/WITHOUT CO-EXISTING DIENTAMOEBA FRAGILIS
Dientamoeba fragilis and Blastocystis hominis are parasites found in the human
digestive tract and many of those infected are asymptomatic carriers. They can,
however, cause a range of gastrointestinal symptoms including diarrhoea and/or
constipation, bloating, flatulence, loss of appetite, abdominal discomfort and pain. In
chronic cases, symptoms can include weight loss, blood in the stool, dizziness, nausea
and vomiting, rectal itching, chronic fatigue and depression. D. fragilis has also been
implicated in some cases of colitis/ bowel inflammation. Many people suffer symptoms
for years before diagnosis and are often misdiagnosed with irritable bowel syndrome
(IBS).
B. hominis was considered harmless until the 1980s. Since then over 100 studies have
accumulated from the Middle East and elsewhere identifying B. hominis as being
pathogenic in immuno-competent adults. To date 10 distinct genotypes of Blastocystis
have been identified in humans and some of these appear to be harmless while others
are pathogenic.
D. fragilis can account for up to 25-50% of Irritable Bowel Syndrome like gastrointestinal
symptoms in those diagnosed with IBS, although it is almost never diagnosed due to our
insensitive testing methods. The majority of stool cultures fail to detect D. fragilis and B.
hominis as these parasites often degenerate a short period after stool collection.
Unfortunately many doctors still believe that these two parasites are harmless and often
ignore them. Research indicates this may not be the case in many suffers and research
also shows that once eradicated symptoms improve greatly. If found to be present you
should treat them to eradicate them from your gut in order to obtain better health.
Blastocystis hominis can be extremely resistant to treatment, and like D.fragilis readily
survives Flagyl which only works in less than 10% of cases. Despite the high failure rate
of this drug it continues to be the drug of choice for many doctors. It is possible to treat
this infection with a combination of drugs – after which, most patients report either a
complete resolution, or a great reduction, in symptoms.
Medication schedule for co-existing Infection:
The patient will take a combination of four medications for 10 days. These will require
two prescriptions from a GP and include:
Script 1
1) Septrin DS (20 Tablets) 2 times a day
2) Doxycycline 50 mg (20 Tablets) 2 times a day
These two are available at any pharmacy
Script 2
1) Diloxinide Furoate 500 mg (30 Capsules) 3 times a day
2) Secnidazole 400 mg (30 Capsules) 3 times a day
These are not commercially available in Australia so are only obtained through a
compounding pharmacy.
Breakfast
Lunch
Dinner
Septrin
DS
1 Tablet
0
1 Tablet
DiloxinideFuroate
500mg
1 Capsule
1 Capsule
1 Capsule
Secnidazole
400 mg
1 Capsule
1 Capsule
1 Capsule
Doxycycline
50 mg
1 Tablet
0
1 Tablet
These medications should be taken at the same time every day with food.
If any sulphur allergy exists then substitute Septrin DS with Noroxin 400mg twice daily
Medication schedule for Blastocystis only
The patient will take a combination of three medications for 10 days. These will require
two prescriptions from a GP and include:
Script 1
1) Septrin DS (20 Tablets) 2 times a day
This is available at any pharmacy
Script 2
2) Diloxinide Furoate 500 mg (30 Capsules) 3 times a day
3) Secnidazole 400 mg (30 Capsules) 3 times a day
These are not commercially available in Australia so are only obtained through a
compounding pharmacy.
Breakfast
Lunch
Dinner
Septrin
DS
1 Tablet
0
1 Tablet
DiloxinideFuroate
Secnidazole
500mg
400 mg
1 Capsule
1 Capsule
1 Capsule
1 Capsule
1 Capsule
1 Capsule
These medications should be taken at the same time every day with food.
If any sulphur allergy exists then substitute Septrin DS with Noroxin 400mg twice daily
These medications have been known to cause the following side effects:
Nausea and vomiting
Headaches
Tiredness
Dizziness
The patient should avoid drinking alcohol for the duration of treatment.
To ensure successful treatment of D. fragilis, B. hominis it is important that the patient
complete the entire 10 day medication schedule.
Follow-up treatment:
Three or four weeks after finishing the treatment protocol the patient should repeat the
stool test to determine whether the parasites have been eradicated. We recommend that
the stool analysis be performed by Metametrix specialist pathologists as they are the
only laboratory we are aware of that uses DNA analysis to identify microbiota which is
far more accurate and sensitive (5000 fold) compared to old stool culture technology
used by most other labs which only positively diagnose about 30% of parasite cases.
This type of DNA testing is not routinely used by most pathologists and is the major
cause of many false negative results. Parasites rapidly breakdown once they leave the
body. This breakdown changes the structure (morphology) of the parasite and thus
makes identification very difficult using old techniques even when staining agents are
added immediately after producing the stool sample. By measuring the presence of their
DNA greatly increases the parasite being correctly identified even if it has already
broken down.
Once treatment (stage 1 - eradication) is complete we recommend the following steps to
help repair the damage caused by the parasites to your gut wall lining. This includes:
Stage 2 – Reinoculate
(1) Prebiotics – Include foods in your diet such as bananas, onion, asparagus, chicory
and burdock root which contain fructose-containing oligosaccharides which are used by
the flora in your gut as nourishment. If you do not like these foods then prebiotic
supplements are also available.
(2) Probiotics – the beneficial bacteria in your gut need to be replaced and we
recommend a potent probiotic like Ultrabiotic 45 made by Bioceuticals which is a high
potency practitioner quality formula containing all the required strains of bacteria at high
doses.
Stage 3 – Repair
Glutamine, essential fatty acids, zinc and panthothenic acid are nutrients that play a vital
role in GUT mucosa cell differentiation, growth and function and thus should be
supplemented to help repair the leaky gut caused by the parasites. We recommend
using Intestamine made by Bioceuticals which was formulated for healing the gut wall
lining as it contains many of the required ingredients for this process to occur. In addition
to a good quality fish oil supplement is also recommended.
Note: The following protocol involves taking antibiotics. If you take the Pill for
contraceptive purposes please be aware that taking antibiotics can reduce the efficacy of
the Pill. Other forms of contraceptive protection must be used.
Drug availability: Septrin and doxycycline are available from most pharmacies whereas
the Diloxinide Furoate and Secnidazole are available only from compounding
pharmacies.