• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Frequently asked questions: ALCOHOL
Frequently asked questions: ALCOHOL

... tobacco and cannabis, alcohol and medications, alcohol and ecstasy. When drugs are mixed the effects may increase or they may produce different and unpredictable reactions. There is no risk-free way of mixing drugs. Drugs obtained illegally may already contain one or more drugs. For example, ecstasy ...
Benfluorex and valvular heart disease
Benfluorex and valvular heart disease

... identified with the following diagnosis-related groups (GHM): 05C02Z, 05C03V, and 05C03W. We also identified patients with one of the four ALD for a cardiovascular disease as it may influence the propensity to develop valvular heart disease. We thus retained the four following diseases: coronary heart ...
No Slide Title
No Slide Title

... – Mendel concluded that inherited characteristics are controlled by factors that occur in pairs. – In his experiments on pea plants, one factor in a pair masked the other. The trait that masked the other was called the dominant trait. The trait that was masked was called the recessive trait. ...
Journal Club - Yale University
Journal Club - Yale University

... • several months to a few years and may involve up to hundreds of patients • “open label,” or not blinded; can be randomized to 2 different doses ...
6.7 CCLHD Standing Protocol-Potassium Additives
6.7 CCLHD Standing Protocol-Potassium Additives

... Date for Review 1The ...
PowerPoint
PowerPoint

... • We found that the analgesic, motor stimulatory and rewarding actions of morphine were enhanced in mice lacking PC2 compared to their wild-type littermates/controls. • We also observed that the number of opioid receptors increased in mice lacking PC2 compared to their wild-type controls. • Addition ...
Supplementary Material for Autozygome Sequencing Expands the
Supplementary Material for Autozygome Sequencing Expands the

... provide a means for ranking the various LoF variants at later stages. A score of 3 was given to alleles that would affect all gene transcripts and where the LoF would impact more than 10% of the ORF. A score of 2 was given to alleles that would impact more than 10% of the ORF but only affected some ...
Hygroton - Medsafe
Hygroton - Medsafe

... 50 mg daily, before and after labour, drug levels in foetal blood were about 15% of those found in maternal blood. The concentrations of chlorthalidone in amniotic fluid were about 4% of maternal blood levels. Effects on ability to drive and use machines Hygroton, especially at the start of treatmen ...
Carbamazepine (Tegretol) Carbamazepine is one of the older drugs
Carbamazepine (Tegretol) Carbamazepine is one of the older drugs

... the tricyclic anti depressant agents . It has been the drug of choice for the treatment of trigeminal neuralgia & is used in treatment of generalised as well as complex partial seizures . It is most frequently prescribed for those patients who have failed to respond to other anti convulsant therapy ...
Medical Genetics for the Practitioner
Medical Genetics for the Practitioner

... in the diagrammatic form of the pedigree. It is a visual representation of the occurrence of specific traits, disorders, or other reproductive events as well as the relationships of individuals in the family. In some instances, the pedigree will provide crucial diagnostic information. This is true e ...
GRADE 12A: Biology 5
GRADE 12A: Biology 5

... Ensure students understand that, in co-dominance, both of the alleles are expressed in the phenotype, whereas, in incomplete dominance, the phenotype has an expression of a feature some way between the phenotypes of the two parental varieties. A human example of co-dominance is in blood grouping. Th ...
ALS Genetics
ALS Genetics

... ALS TDI has run more drugs in SOD1 mice than the entire academic community combined ...
New Treatment for Patients with Refractory Metastatic Colorectal
New Treatment for Patients with Refractory Metastatic Colorectal

... in adults who have had previous treatment with available therapies including fluoropyrimidine-, oxaliplatin- or irinotecan-based chemotherapies, anti-vascular endothelial growth factor (VEGF) agents and anti-epidermal growth factor receptor (EGFR) agents, or when these therapies are not suitable.1 T ...
second of Chapter 17, Molecular Evolution and Population Genetics
second of Chapter 17, Molecular Evolution and Population Genetics

... For example, the probability of producing 2 blue gametes for individual A is 1/2 x1/2 = 1/4. Similarly, the probability of producing 2 red gametes is also 1/4, but the probability of producing a red and a blue gamete is 1/2 (1/4 + 1/4). FA is the inbreeding coefficient of the individual producing th ...
Med-Psych Drug-Drug Interactions Update Triptans
Med-Psych Drug-Drug Interactions Update Triptans

... et al., no significant clinical events occurred, and the authors suggested that no dose adjustment was necessary. These modest findings reflect almotriptan’s multiple avenues of metabolism, which allow the drug to be biotransformed despite “roadblocks” at some of its metabolic sites. We could not fi ...
Topic 10: Genetics (HL)
Topic 10: Genetics (HL)

... 10.2.2 Distinguish between autosomes and sex chromosomes 10.2.3 Explain how crossing over between non-sister chromatids of a homologous pair in prophase I can result in an exchange of the alleles ...
АНАЛГЕЗИВНІ ЗАСОБИ
АНАЛГЕЗИВНІ ЗАСОБИ

... • Acts longer than morphine (approximately 6 hours) • Analgesic activity is higher than of morphine, that’s why it’s used in doses of 0,3-0,6 mg • In case of breathing depression, which it causes, naloxon is less effective since buprenorphine is slowly released from the connection with mu-receptors ...
1. circumstances when shared care is appropriate
1. circumstances when shared care is appropriate

...  Do you have the relevant knowledge, skills and access to equipment to allow you to monitor treatment as indicated in this shared care prescribing guideline?  Have you been provided with relevant clinical details including monitoring data? If you can answer YES to all these questions (after readin ...


... a trend towards better compliance with the written package insert for Diskhaler than with Turbuhaler. In the latter case, noncompliance was principally associated with the loading angle, although a case of exhalation into the device was noted. The Turbuhaler drug reservoir nominally provides 200x 50 ...
3368 - Isomer Design
3368 - Isomer Design

... Health Canada Santé Canada ...
Law (Principle) of Dominance The law (principle) of dominance
Law (Principle) of Dominance The law (principle) of dominance

...  An organism with a dominant allele for a particular trait will always have that trait expressed (seen) in the organism.  An organism with a recessive allele for a particular trait will only have that trait expressed when the dominant allele is not present. Since organisms received one gene for a ...
carbidopa/levodopa (kar-bi-doe-pa/lee-voe-doe-pa) - DavisPlus
carbidopa/levodopa (kar-bi-doe-pa/lee-voe-doe-pa) - DavisPlus

... ● For orally disintegrating tablets, just prior to administration remove tablet from bottle with dry hands. Immediately place tablet on top of tongue. Tablet will dis- ...
Stieprox - GlaxoSmithKline
Stieprox - GlaxoSmithKline

... olamine 10 times that of a topical human dose, have revealed no significant evidence of impaired fertility or harm to the fetus. STIEPROX® should only be used during pregnancy if the potential benefits to the mother justify the potential risks to the fetus. No pregnant women were enrolled during cli ...
3367 - Isomer Design
3367 - Isomer Design

... Health Canada Santé Canada ...


... function tests became abnormal no changes in their fluconazole therapeutic regime were required. At follow-up liver function tests tended to return to normal. No correlation was found between liver enzyme abnormalities and the patients' age, sex, weight, previous liver disease, or abnormal liver enz ...
< 1 ... 650 651 652 653 654 655 656 657 658 ... 1254 >

Pharmacogenomics

Pharmacogenomics (a portmanteau of pharmacology and genomics) is the study of the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with drug absorption, distribution, metabolism and elimination, as well as drug receptor target effects. The term pharmacogenomics is often used interchangeably with pharmacogenetics. Although both terms relate to drug response based on genetic influences, pharmacogenetics focuses on single drug-gene interactions, while pharmacogenomics encompasses a more genome-wide association approach, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.Pharmacogenomics aims to develop rational means to optimize drug therapy, with respect to the patients' genotype, to ensure maximum efficacy with minimal adverse effects. Through the utilization of pharmacogenomics, it is hoped that drug treatments can deviate from what is dubbed as the “one-dose-fits-all” approach. It attempts to eliminate the trial-and-error method of prescribing, allowing physicians to take into consideration their patient’s genes, the functionality of these genes, and how this may affect the efficacy of the patient’s current and/or future treatments (and where applicable, provide an explanation for the failure of past treatments). Such approaches promise the advent of ""personalized medicine""; in which drugs and drug combinations are optimized for each individual's unique genetic makeup. Whether used to explain a patient’s response or lack thereof to a treatment, or act as a predictive tool, it hopes to achieve better treatment outcomes, greater efficacy, minimization of the occurrence of drug toxicities and adverse drug reactions (ADRs). For patients who have lack of therapeutic response to a treatment, alternative therapies can be prescribed that would best suit their requirements. In order to provide pharmacogenomic-based recommendations for a given drug, two possible types of input can be used: genotyping or exome or whole genome sequencing. Sequencing provides many more data points, including detection of mutations that prematurely terminate the synthesized protein (early stop codon).
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report