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Chapter 13: Antimicrobial Therapy
Chapter 13: Antimicrobial Therapy

... •They catalyze the breaking of the B-lactam ring in penicillins and some cephalosporins First-Line, Second-Line Third-Line Drugs •1930’s sulfonamides were found to cure the disease, gonorrhea •Sulfonamide-resistant strains developed and penicillin was used as a cure •Penicillin-resistant strains dev ...
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Bacterial morphological plasticity

Bacterial morphological plasticity refers to evolutionary changes in the shape and size of bacterial cells. As bacteria evolve, morphology changes have to be made to maintain the consistency of the cell. However, this consistency could be affected in some circumstances (such as environmental stress) and changes in bacterial shape and size, but specially the transformation into filamentous organisms have been recently showed. These are survival strategies that affect the bacterial normal physiology in response for instance to innate immune response, predator sensing, quorum sensing and antimicrobial signs.
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