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Rhythms That Go Bump in the Night
Rhythms That Go Bump in the Night

... disease, in patients with atrioventricular block and in toxic reactions to digitalis, quinidine and procaine amide. Occasionally, it succeeds ventricular tachycardia. This paper presents additional experiences confirming the clinical value of external countershock in terminating ventricular tachycar ...
Guidelines for Heart Failure in the Adult
Guidelines for Heart Failure in the Adult

... Failure in Adults. The guideline is available at: http://www.acc.org/clinical/statements.htm Heart failure is defined as a “complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood.” Cardinal ma ...
Heart Failure Dr Nidhi Bhargava
Heart Failure Dr Nidhi Bhargava

... each titration , use those licensed for HF (even in pts with COPD) ...
SIMDAX (levosimendan)
SIMDAX (levosimendan)

Athero Arteriosclorsis
Athero Arteriosclorsis

... and on your artery walls (plaques), which can restrict blood flow. These plaques can burst, triggering a blood clot. Although atherosclerosis is often considered a heart problem, it can affect arteries anywhere in your body. Atherosclerosis usually is preventable and is treatable. Both can cause hea ...
The IONA Study and Results
The IONA Study and Results

... The results of this landmark study confirmed nicorandil’s ability to protect the heart in patients with chronic stable angina of effort. The investigators found that nicorandil significantly reduced the combined endpoints of death from coronary heart disease, non-fatal myocardial infarction and unpl ...
C-Pulse Clinical Experience
C-Pulse Clinical Experience

... Class IV—Inability to carry on any physical activity without discomfort. Symptoms of heart failure or the angina syndrome may be present even at rest. If any physical activity is undertaken, discomfort is increased. ...
job description
job description

... The SNAHFS is an integrated part of the West of Scotland Heart and Lung Centre at The Golden Jubilee National Hospital. As well as the cardiac transplant service, there is a recently established mechanical circulatory support (or VAD) programme. The unit works closely with the local and regional car ...
Popular Links
Popular Links

... ACC/AHA since 2005 for those heart failure patients with ICM greater than 30 days out from MI and EF<30% or NICM with EF<35%. MIRACLE trial in JAMA in 2003 led to current recommendations for combination ICD therapy +cardiac resynchronization therapy in those patients w/ EF < 35% & NYHA class 3-4 sym ...
wall motion analysis in crt non-responders
wall motion analysis in crt non-responders

... Asklepios Klinik St. Georg, Cardiology, Hamburg, Germany Introduction: The introduction of cardiac resynchronisation therapy (CRT) in patients with chronic heart failure and left bundle brunch block has improved their outcome. However, there is a rate of non-response in over 30%, particularly in pat ...
Congestive Heart Failure
Congestive Heart Failure

... <4 cm/m2 LV End-Diastolic Dimension ...
Hammock Bridge on Fire: Complete AV Block in a Patient
Hammock Bridge on Fire: Complete AV Block in a Patient

... Aims: To recognize heart block as a complication associated with congenitally-corrected transposition of the great arteries (CCTGA). Presentation of the Case: A healthy 36 year old male with CCTGA presented with syncope as a manifestation of heart block. A unique feature of this case was the presenc ...
V. Electrocardiogram (EKG or ECG
V. Electrocardiogram (EKG or ECG

... Heart Contraction Overview V. Electrocardiogram (EKG or ECG)- record impulses by detecting electrical currents in heart; measures voltage (mV), not contractions. Impulses lead to contractions. 1. Unique characteristics of cardiac muscle: 1.Stimulation- autorhythmicicity; depolarize spontaneously 2.O ...
3Rd degree block
3Rd degree block

... Progressive lengthening of P-R interval until QRS is dropped and then pattern repeats. No 1:1 Conduction Causes: Drug Digoxin and Beta Blockers, MI, CAD or ischemic changes. TX: give Atropine to speed up may need temp. pacemaker. IV. 2nd degree A-V block Type II QRS is dropped without warning No len ...
N120 Quiz #1 (20 Items): REVIEW BLUEPRINT
N120 Quiz #1 (20 Items): REVIEW BLUEPRINT

... Sinus tachycardia has a normal sinus rhythm, but the SA node fires at a rate greater than 100 beats/minute as a result of vagal inhibition or sympathetic stimulation. o Clinical associations. Sinus tachycardia is associated with physiologic and psychologic stressors such as exercise, fever, pain, hy ...
The Structural Heart Disease Program your partners for advanced
The Structural Heart Disease Program your partners for advanced

... CATH LAB EXPERTS Catheter-based treatment of structural heart disease is rapidly evolving. As technology advances, and new treatment options become available, one thing remains the same: the need for interventionalists, cardiac surgeons, general cardiologists and cardiac imaging specialists to colla ...
Twiddler`s syndrome: a rare cause of implantable cardioverter
Twiddler`s syndrome: a rare cause of implantable cardioverter

... Published on behalf of the European Society of Cardiology. All rights reserved. & The Author 2015. For permissions please email: [email protected]. ...
One-credit Independent Study Proposal - NUCATS
One-credit Independent Study Proposal - NUCATS

... preserved ejection fraction (HFpEF) are becoming more prevalent. Whether due to a common etiology or arising independently, CKD and HFpEF are often coincident in patients. Furthermore, the patient population with both problems is expanding. Importantly, renal dysfunction has been associated with wor ...
The Role of Cardiac Surgery in Treatment of Chronic Heart Failure
The Role of Cardiac Surgery in Treatment of Chronic Heart Failure

... of view the implantation is fairly simple and does not require the use of extracorporeal circulation. It can be complemented with reduction mitral annuloplasty or/and cardiac resynchronization therapy. Another surgical option, which has become immensely popular in the last decade, is implantation of ...
Arrhythmogenic Right Ventricular Cardiomypathy (ARVC)
Arrhythmogenic Right Ventricular Cardiomypathy (ARVC)

... Major advances have been made in genetic testing for ARVC in recent years. Genetic testing is now commercially available and involves screening five genes that can cause the condition. The gene alteration will be identified in approximately 40-50% of families. Further research is needed to identify ...
Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy

... Diagnosis Code(s) (if known): Please check all that apply to the individual: Request is for FDA-approved biventricular pacemaker for cardiac resynchronization therapy (CRT) Request is for a FDA-approved ICD, in combination with cardiac resynchronization therapy (CRT/ICD) (*** If checked, you must co ...
Acute Heart Failure - Advocatehealth.com
Acute Heart Failure - Advocatehealth.com

... hospitalization in patients over 65 1 million hospitalizations per year with HF as primary diagnosis 2.5 million hospitalizations with heart failure as secondary diagnosis ...
V-Heft I Study - Clinical Trial Results
V-Heft I Study - Clinical Trial Results

... Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure Results of a Veterans Administration Cooperative Study (V-HEFT I) • Multicenter, randomized, double-blind, placebocontrolled trial • 642 men followed for an average of 2.3 years • Patient History: – Men with impaired card ...
Cardiac anatomy and physiology
Cardiac anatomy and physiology

... -pulmonary veins carry oxygenated blood from the lung to the left side of the heart. -Aorta carry oxygenated blood from the left side of the heart to the rest of the body. -Aortic semilunar valve, prevent blood back-flow into the left ventricles during ventricular repolarization -Tricuspid valve all ...
Title: The Cardiac Conduction System
Title: The Cardiac Conduction System

... 1- Introduction: The inherent and rhythmical electrical activity in the heart is responsible for its continuous beating. The source of this beating is a group of highly specialized cells called the autorhythmic cells. a- These cells are self-excitable b- They repeatedly generate action potentials th ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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