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Congestive Heart Failure - Missouri Alliance for Home Care
Congestive Heart Failure - Missouri Alliance for Home Care

... May feel tired for up to 6 weeks while titrating to final dose Takes 3 full months of therapy to begin seeing the positive i i benefits b fi Using a combination beta/alpha blocker may decrease the negative effects early in therapy by decreasing afterload (Coreg) Inform patients that this is a longlo ...
clinical letter - Pocono Medical Center
clinical letter - Pocono Medical Center

... ischemic and nonischemic cardiomyopathy #LVEF less than or equal to 35'$ patients with NYHA Class II or III symptoms were included. This trial showed that ICDs reduced all"cause mortality by 23' compared to Amiodarone or a placebo. In fact, Amiodarone did as well as the placebo. Michel Mirowski #192 ...
Beta Blockers CAUSE Heart Attacks
Beta Blockers CAUSE Heart Attacks

... the time of surgery are four times more likely to suffer heart attacks and death than patients who are not given such drugs, according to a study conducted by researchers from the Veterans Affairs (VA) Boston Health Care System and published in the journal Archives of Surgery. Because many surgeries ...
Galaxy CRT-D Brochure
Galaxy CRT-D Brochure

... Always have external defibrillation equipment available during implant and electrophysiologic testing. Ensure that an external defibrillator and medical personnel skilled in CPR are present during post-implant device testing should the patient require external rescue. Advise patients to seek medical ...
PD233: Design of Biomedical Devices and Systems
PD233: Design of Biomedical Devices and Systems

... Augmented limb leads aVR= 2/3(RA- Vw) aVL= 2/3(LA- Vw) aVF= 2/3(LL- Vw) ...
Corrected Article
Corrected Article

... Active clinical trials and ongoing preclinical work are advancing the development of cell-based therapies for heart failure and vascular disease. Clinical trial designs are taking on an increasingly sophisticated design in order to test and compare whole bone marrow and its leading constituents, as ...
Overview-Arrhythmias are caused by disturbances of the electrical
Overview-Arrhythmias are caused by disturbances of the electrical

... atrial muscle. A delay occurs as the charge passes through atrial ventricular (AV) node, made up of specialized atrial tissue. The charge then passes through the single pathway A-V bundle (Bundle of His) in the ventricle before it divides into the right and left bundle branches. ECG: The normal ECG ...
VALITUDE™ X4 CRT-P System Overview Brochure
VALITUDE™ X4 CRT-P System Overview Brochure

... INDICATIONS AND USAGE: Boston Scientific cardiac resynchronization therapy pacemakers (CRT-Ps) are indicated for patients with moderate to severe heart failure (NYHA Class III/IV) including left ventricular dysfunction (EF ≤35%) and QRS duration ≥ 120 ms and remain symptomatic despite stable optimal ...
Take the EF and SCA Challenge!
Take the EF and SCA Challenge!

... Take the EF and SCA Challenge! Current medical research and guidelines are focusing more attention on ejection fraction as a way to help heart patients and their clinicians make better decisions about their care, particularly heart patients who may be at risk for sudden cardiac arrest (SCA). Test yo ...
Cardiomyopathy in pregnancy
Cardiomyopathy in pregnancy

... Levosimendan a cardiotropic agent that improves cardiac output by increasing the response of myofilaments to intracellular calcium unlike the above mentioned traditional inotropes that do so by increasing the intracellular calcium itself. Levosimendan is used as an intravenous infusion at the rate ...
Metabolic syndrome and prognosis of ischemic mitral insufficiency
Metabolic syndrome and prognosis of ischemic mitral insufficiency

... MI in terms of prognosis after revascularization. Publications relating to the incidence of ischemic MI in MetSy patients are insignificant. Methodology: MetSy is defined by International Diabetes Foundation criteria. MI is graded from 1+ to 4+, as mild (group I ≤ 1+), moderately severe (group II> ≤ ...
He also wants to know if his brother`s heart can recover
He also wants to know if his brother`s heart can recover

... underlying cause of the MI. “When coronary blood flow is interrupted for an extended period of time, myocyte necrosis occurs”….”Cardiac cells can withstand ischemic conditions for about 20 minutes before cellular death takes place” (McCance & Huether, 2006, pg. 1111). The areas affected will be repl ...
Vericel to Present Data at the American Heart Association`s
Vericel to Present Data at the American Heart Association`s

... always, made through the use of words or phrases such as "anticipates," "intends," "estimates," "plans," "expects," "we believe," "we intend," and similar words or phrases, or future or conditional verbs such as "will," "would," "should," "potential," "can continue," "could," "may," or similar expre ...
Adipose Stem Cell Heart Attack Trial Data Published in Journal of
Adipose Stem Cell Heart Attack Trial Data Published in Journal of

... No side effects from ADRC delivery, processed using Celution® ❍ No increase in arrhythmias Feasibility ❍ Improvement in cardiac function by SPECT ❍ Improvement in blood flow into the heart muscle (perfusion defect) ❍ Reduction in scar formation (infarct size) ...
Pharmacological management of acute heart failure
Pharmacological management of acute heart failure

... progresses to a chronic state, thus it is recommended that the patient is followed-up in a heart failure programme. Therefore, long-term goals as described in the guidelines comprise of educating and initiating appropriate lifestyle adjustments, providing secondary care, improving quality of life an ...
Procoralan Ivabradine Prescribing Information Refer to
Procoralan Ivabradine Prescribing Information Refer to

... Refer to Summary of Product Characteristics (SPC) before prescribing. Presentation: Film-coated tablets, 5mg, 7.5mg. Indications: Symptomatic treatment of Chronic stable angina pectoris: in coronary artery disease adults with normal sinus rhythm and heart rate ≥ 70 bpm. Indicated in patients unable ...
The Heart Anatomy Questions
The Heart Anatomy Questions

... trunk to the _c___ to the capillary beds of the lungs to the _d___to the __e__ of the heart through the _f__ valve to the __g__through the __h__ valve to the _i_ to the systemic arteries to the __j___ tissues to the systemic veins to the __k___ and __l__ entering the right atrium of the heart. 3. If ...
Chapter 20
Chapter 20

... b. Heart failure is caused by a cardiomyopathy. c. Cardiomyopathy is caused by heart failure. d. Heart failure and cardiomyopathy are unrelated. ...
Co-ordination of the Cardiac Cycle
Co-ordination of the Cardiac Cycle

... contraction of the ventricles. • Electrical impulse passes to ventricles via AV node and the Bundle of His. They pass the impulse to the base of the ventricles (~ 0.1 s delay). • The bundle of His is a group of fibres that conduct impulses to Purkyne fibres which carry impulses to left & right ventr ...
Transcatheter aortic valve implantation: anesthetic
Transcatheter aortic valve implantation: anesthetic

... regurgitation. It evaluated the Corevalve function, measured aortic regurgitation and assessed for aortic dissection, pericardial effusion and myocardial ischemia. Result: Patients were 79 ± 7 years (63%male), with multiple comorbidities (EuroSCORE = 22,16 ± 9,74%). Patients who survived to the proc ...
Heart Diseases
Heart Diseases

... can demonstrate the thrombus • If late (>12 hours), thrombus is demonstrated in only 60% of cases, due to fibrinolysis • Early administration of thrombolytics limit the degree of cardiac infarction ...
Left Ventricular Assist Device (LVAD)
Left Ventricular Assist Device (LVAD)

... ventricles. The development of LVAD began in the 1960s as a bridge to cardiac transplant. It has evolved into a “destination therapy,” meaning a permanent therapy rather than a transitional stage until another therapy. The indication for LVAD candidates is New York Heart Association class 4 heart fa ...
Advanced Heart Failure Therapies: Arrhythmia in End
Advanced Heart Failure Therapies: Arrhythmia in End

... Non-significant trend toward higher risk of ventricular tachycardia among low responders compared to ICD-only patients (p = 0.074) ...
Management of congestive heart failure on a budget
Management of congestive heart failure on a budget

... Heart failure is a syndrome where the heart cannot pump blood at the rate required to supply the metabolic demands of tissues and maintain normal pressures. CHF is whereby abnormal cardiac function results in the accumulation and retention of water and sodium, most frequently resulting in pulmonary ...
Cardiac referral form
Cardiac referral form

... Alcohol (units/week) BMI (kg/m2) Cholesterol ...
< 1 ... 655 656 657 658 659 660 661 662 663 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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