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Cardiac Resynchronisation Therapy in Patients with NYHA Class I-II
Cardiac Resynchronisation Therapy in Patients with NYHA Class I-II

... In studies including 3- to 6-months of follow-up, CRT, either alone or combined with an implantable cardioverter-defibrillator (ICD), has been shown to improve symptoms, exercise tolerance, and quality of life [14, 15, 20] and to reverse LV remodelling [16–18] in patients with moderate to severe HF ...
Summary of Factors that Regulate Cardiac Output
Summary of Factors that Regulate Cardiac Output

... channels and what is the purpose of these channels in those cells? 3. Suppose your sinoatrial node pacemaker cells ceased working. Would your heart continue to beat, and if so, would it beat faster or slower than before? Explain. ...
Document
Document

... each center to serve 5-10million population referral relationships with primary caregivers association with transplant centre ...
Steroids In caRdiac Surgery (SIRS) Trial
Steroids In caRdiac Surgery (SIRS) Trial

... Did not receive study drug (n = 105) ...
BIOL242CardioVascularChap18,19ObjSEP2012
BIOL242CardioVascularChap18,19ObjSEP2012

... 2. Know the layers of the heart wall and the composition of the pericardium. 3. Describe the structure and function of each part of the heart including: the right and left atria, right and left ventricles, semilunar valves, tricuspid and bicuspid valves, chordae tendinae, papillary muscles, pulmonar ...
Issues in Heart Failure
Issues in Heart Failure

... ß-blocker or verapamil  atrial fibrillation: attempt restoration of sinus rhythm  ACE-inhibitors, spironolactone: may cause regression of hypertrophy  cautious use of diuretics  digoxin unhelpful ...
ACC/AHA 2005 Guideline Update for the Diagnosis and
ACC/AHA 2005 Guideline Update for the Diagnosis and

... Worsening NYHA functional status. Hyponatremia. Decreased peak exercise O2 uptake. Anemia. Wide QRS. Chronic hypotension. Resting tachycardia. Renal Insuficiency. Refractory volume overload. BNP levels inpatient may predict readmission and death, and adverse events after MI. ...
National Imaging Associates, Inc. Clinical guidelines HEART
National Imaging Associates, Inc. Clinical guidelines HEART

... and extent of coronary artery disease (CAD) as well as ventricular and valvular function. It can be used to perform various tests, including angiography, intravascular ultrasonography, and measurement of cardiac output (CO), detection and quantification of shunts, endomyocardial biopsy, and measurem ...
Heart introduction
Heart introduction

... layers—a tough, fibrous covering and a secretory lining. The outer fibrous covering of the sac attaches to the connective tissue partition that separates the lungs. This attachment anchors the heart so that it remains properly positioned within the chest. The sac’s secretory lining secretes a thin p ...
MADIT II - Primary Prevention of SCD - 2004
MADIT II - Primary Prevention of SCD - 2004

... • 70% of Patients were Class II NYHA (Typically less sick than in previous ICD trials) • 48% of Patients were non-ischemic ...
Clinical Use of Antiarrhythmic Agents
Clinical Use of Antiarrhythmic Agents

... A firm arrhythmia diagnosis should be established. For example, the misuse of verapamil in patients with ventricular tachycardia mistakenly diagnosed as supraventricular tachycardia can lead to catastrophic hypotension and cardiac arrest. As increasingly sophisticated methods to characterize underly ...
Unit 2
Unit 2

... 2. Know the layers of the heart wall and the composition of the pericardium. 3. Describe the structure and function of each part of the heart including: the right and left atria, right and left ventricles, semilunar valves, tricuspid and bicuspid valves, chordae tendinae, papillary muscles, pulmonar ...
“Less Sick” Patients?
“Less Sick” Patients?

... at 1 and 2 years, respectively. That should be the target for LVAD therapy.2 Multiple studies have also shown an improvement in functional capacity and quality of life in patients with LVADs over medical therapy.3 It could then be imputed that it would be beneficial to implant LVADs if the survival ...
Transfer of NYHA 1-2 Heart Failure Patients to Primary Care
Transfer of NYHA 1-2 Heart Failure Patients to Primary Care

... (Simpson's bi plane ejection fraction 26%). Moderately dilated right ventricle with preserved systolic function. Moderate bi atrial dilatation. No significant valvular heart disease. Moderate pulmonary hypertension (estimated RV systolic pressure 45-50mm Hg). No pericardial disease. Other Investigat ...
Abstract ECMO
Abstract ECMO

... contribution of albumin dialysis using Molecular Adsorbent Recirculating System to improve CCBpoisoned patients with refractory vasodilatation. Lipid emulsion has been extensively used to treat severe symptoms attributed to cardiotoxicants. However, due to the lack of randomized controlled studies, ...
a new prognostic factor even in patients with heart failure
a new prognostic factor even in patients with heart failure

... data of the COMMIT-HF registry, reported im­ portant findings on the role of the NLR in pre­ dicting long­‑term mortality in patients with HF of different etiologies. In this large cohort (1734 patients), a high NLR was significantly associat­ ed with an increased risk of 12-month all-cause mortalit ...
Slide 1 - Access Emergency Medicine
Slide 1 - Access Emergency Medicine

... A: Undersensing. The fifth beat is a premature ventricular contraction (PVC). The next beat is a ventricular paced beat. Note that the paced beat occurs soon after the PVC, indicating a failure to sense the preceding complex. B: The first and second beats are paced and the third and fourth beats sho ...
the peculiarities of wolf-parkinson-white syndrome in children at the
the peculiarities of wolf-parkinson-white syndrome in children at the

... Regional Children Clinical Hospital Kharkiv, Ukraine The aim of our research is to study the peculiarities of Wolf-Parkinson-White syndrome in children at the present stage. Materials and methods. We have performed retrospective analyses of 71 in-patient cards of 39 children with WPW on the basis of ...
The growing epidemic of Adult Congenital Heart Disease
The growing epidemic of Adult Congenital Heart Disease

... >30% reduction in mortality was reported among patients with congenital heart disease 67% mortality reduction in children with complex lesions ...
Slajd 1 - Patho
Slajd 1 - Patho

... Disorders of cardiac conduction ...
Study Guide for Chapter 12, Part 2 – The Heart Terms – know the
Study Guide for Chapter 12, Part 2 – The Heart Terms – know the

... intercalated discs, left AV (bicuspid or mitral) valve, papillary muscle, pericardium, pulmonary semilunar valve, pulmonary trunk and arteries, pulmonary veins, Purkinje fibers, right and left bundle branches, right AV (tricuspid) valve, systole, vein, vena cavae (superior and inferior), vein, venou ...
CardioCard - bei Legon Informatik
CardioCard - bei Legon Informatik

... DEFIBRILLATOR (ICD) Like a cardiac pacemaker, the ICD is an instrument designed to treat disturbances of cardiac rhythm. Unlike the standard pacemaker, however, it is also used to treat rapid arrhythmias (tachycardia, ventricular fibrillation). Because both detection and treatment are more difficult ...
Two Cardiology Zebras - Iowa Heart Foundation
Two Cardiology Zebras - Iowa Heart Foundation

... during the acute phase •  This disappeared during the chronic phase. •  The interval between these left ventriculograms from acute to chronic phase was 51 days. ...
A Machine Without an Owner`s Manual
A Machine Without an Owner`s Manual

... durability of these hemodynamic changes and the potential that ramp testing should be repeated with some frequency must be addressed. ...
File
File

... If The Mechanisms Listed Above Adequately Restore Cardiac Output, Then The Heart Failure Is Said To Be Compensated . If The Adaptive Mechanisms Fail To Maintain Cardiac Output, The Heart Failure Is ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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