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Cardiac Resynchronization Therapy
Cardiac Resynchronization Therapy

... Diagnosis Code(s) (if known): Please check all that apply to the individual: Request is for FDA-approved biventricular pacemaker for cardiac resynchronization therapy (CRT) Request is for a FDA-approved ICD, in combination with cardiac resynchronization therapy (CRT/ICD) (*** If checked, you must co ...
Congestive Heart Failure
Congestive Heart Failure

... ◦ Presence of advanced heart disease with continued heart failure symptoms requiring aggressive medical therapy ...
A dog`s heart can beat over 73,000,000 times a year! A cat`s heart
A dog`s heart can beat over 73,000,000 times a year! A cat`s heart

... The heart sits on a 45 degree angle between the front legs of dogs and cats with the top or base of the heart pointing towards the head. Humans, dogs and cat hearts are near identical. Slight differences exist in a few valves and the coronary vessels, or blood vessels that feed the heart itself. Die ...
Electrical activity in the heart
Electrical activity in the heart

... recovery stage is also known as the refractory period – during that stage it is unable to conduct another nerve impulse until it is back in the resting stage. Electrical activity can be monitored using an electrocardiogram or ECG. A standard ECG trace is shown below and consists of a series of waves ...
Heart Failure Associate Professor Rob Doughty Dept of Medicine
Heart Failure Associate Professor Rob Doughty Dept of Medicine

... • Biventricular pacing (cardiac resynchronisation therapy, CRT) – Pace right and left ventricle (via lead in coronary sinus) – Improved cardiac output in severe HF – Improved quality of life – Improved survival ...
Simulating Initiation and Termination of Reentry in
Simulating Initiation and Termination of Reentry in

... – Bradycardia - less than 60 beats per min. – Tachycardia - pace of the heart is faster than the regulatory signal from the sinus node (over 100 beats per min). • Rapid heart beating in the ventricles can be life-threatening. (ex. Ventricular fibrillation heart can’t pump any blood) Currently, over ...
Introduction to Electrophysiology
Introduction to Electrophysiology

...  Unexplained syncope and known structural heart disease.  Palpitations and documented inappropriate rapid pulse rates ...
1. Match the words with their synonyms or definitions 1
1. Match the words with their synonyms or definitions 1

... 2. Listen and answer the questions: The contraction of the heart muscle is caused by ____________. The abbreviation for electrocardiogram is ________ or _________. What are the individual phases of electrocardiogram and what happens during them. 3. Complete the gaps with only ONE most suitable word: ...
Document
Document

... – It decreases LV Volumes & improves LV Systolic Function (LVEF.) – It decreases the degree of Mitral Regurgitation. – It leads to LV Reverse Remodeling. ...
Protocol of investigation of sudden cardiac death at post
Protocol of investigation of sudden cardiac death at post

... coronary thrombosis was identified in 47% of 202 out of hospital sudden cardiac deaths in Nottingham UK. • Last year we identified 70 patients who died at home with coronary thrombosis or acute infarction. What prevents these patients getting to hospital? Leach et al Eur Heart J 1995;16:1181-5 ...
CVS Physiology
CVS Physiology

... Anaesthetic agents in general affect the heart, the peripheral vessels, the baroreceptors and the autonomic nervous system to a varying degree. 1. Preload: reduction in venous tone, more with ...
Acute Myocardial Infarction Gusto
Acute Myocardial Infarction Gusto

... Post MI EF<30 Randomized ICD/Medical F/U 20 months Severe renal dysfunction to be the most powerful predictor of all-cause mortality ...
Heart Check
Heart Check

... Heart Check ...
Critical Left Ventricular Outflow Tract Obstruction Study
Critical Left Ventricular Outflow Tract Obstruction Study

... Assemble a multi-institutional inception cohort of infants with critical LVOTO undergoing all currently available treatment strategies Identify risk factors that are predictive of late outcomes Determine the value of emerging management strategies Assess late outcomes by functional assessment, quali ...
Randomized, double blind study of non
Randomized, double blind study of non

... care for patients with symptomatic heart failure and delayed myocardial activation, indexed by a prolonged QRS duration.1 CRT improves ventricular contractile strength, quality of life, exercise tolerance, and reduces mortality and hospitalizations. However, it is estimated that less than half of he ...
Heart Failure Whistle Stop Talks
Heart Failure Whistle Stop Talks

... ‘....the two terms LVSD and HFPEF have several limitations. These include the variability of the left ventricular ejection fraction measured by different imaging modalities, and the lack of universal agreement on the threshold of ejection fraction at which LVSD and preserved ejection fraction are de ...
Unstable Angina and Non–ST Elevation Myocardial Infarction
Unstable Angina and Non–ST Elevation Myocardial Infarction

... Killip class II or higher (precipitating cardiogenic shock) ...
Cardiac Muscles Functioning of the heart
Cardiac Muscles Functioning of the heart

... • Action potential spread through the bundle of His bundle branches and Purkinje fibers causing ventricular depolarization. • Ventricular depolarization (QRS complex) induces ventricular systole. • As action potential pass out of the ventricles, ventricular diastole is ...
Cardiology - Congestive Heart Failure
Cardiology - Congestive Heart Failure

... nonsteroidal anti-inflammatory drugs and other drugs which can lead to fluid retention such as rosglitazone (Avandia™). 6. Importance of age, gender and ethnicity on the prevalence and prognosis of CHF 7. Physiological basis and scientific evidence supporting each type of treatment, intervention, or ...
1. Apply the pathophysiology of heart failure (HF) to the rationale for
1. Apply the pathophysiology of heart failure (HF) to the rationale for

... 1. Apply the pathophysiology of heart failure (HF) to the rationale for specific drug therapies for HF with reduced ejection fraction (EF) and HF with preserved EF. 2. Evaluate the clinical signs and symptoms of HF, and determine the need for referral to a higher level of care. 3. Given a patient ca ...
Case Study 1 Can Mr. H.`s brother`s heart recover? There are some
Case Study 1 Can Mr. H.`s brother`s heart recover? There are some

... Skinner, J.S., Cooper, A., & Feder, G.S. (2007). Secondary prevention for patients following a myocardial infarction: summary of NICE guidelines. Heart, 93: 862-864. ...
Guidelines for Management of Congenital Heart Disease in Adults
Guidelines for Management of Congenital Heart Disease in Adults

... 4. Specific types of CHD are classified as being of simple, moderate, or great complexity, with specific recommendations for the clinician training levels and patient access required to manage each condition. 5. The authors emphasize the recognition of the complex psychosocial issues encountered by ...
Congestive Heart Failure - California Health Information Association
Congestive Heart Failure - California Health Information Association

... it to do so only from an abnormally elevated ventricular diastolic pressure. Signs and Symptoms of CHF ...
Cardiac Stimulants and Depressants
Cardiac Stimulants and Depressants

... The Heart  Main pacemakers of heart:  Sinoatrial node: 60-100 bpm; primary ...
What are the Current Pacemaker and ICD Indications
What are the Current Pacemaker and ICD Indications

... • Avoids risks associated w/ endovascular lead extraction ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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