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Control of the cardiac cycle
Control of the cardiac cycle

... atrioventricular node and the purkyne tissue. • Interpret and explain electrocardiogram (ECG) traces with reference to normal and abnormal heart activity. ...
A. Marc Gillinov Commentary - AATS
A. Marc Gillinov Commentary - AATS

... The reported success rate of coronary venous lead implantation for CRT ranges from 81% to 99%. Causes of failed percutaneous lead placement may be anatomic (superior vena cava or coronary sinus obstruction or inadequate coronary venous anatomy) or technical (failure to cannulate the coronary sinus, ...
Heart Failure read code guide
Heart Failure read code guide

... Please reserve the use of the cardiomyopathy read codes for those patients that have been diagnosed by a specialist and receive specific treatment. For example those with post partum cardiomyopathy or arrhythmogenic right ventricular cardiomyopathies. For those that have a cardiomyopathy and the lef ...
Heart Support
Heart Support

... These results suggest that intravenous magnesium sulfate may be effective in the acute management of cardiac arrhythmias in patients with a low serum iMg2+ level.3 The intricate role of magnesium on a biochemical and cellular level in cardiac cells is crucial in maintaining stable cardiovascular hem ...
Implanted pressure monitoring device improves heart
Implanted pressure monitoring device improves heart

... The first implantable hemodynamic monitoring device for heart failure is now available to eligible patients at UCLA. The CardioMEMS HF System was approved by the Food and Drug Administration in 2014 as the first implantable heart failure monitoring device that has been shown to significantly reduce ...
Heart failure Ventricular insufficiency Left heart failure (LHF
Heart failure Ventricular insufficiency Left heart failure (LHF

... – SNS ⇒ ↑ HR, + ino, + bathmo, +dromo effects ⇒ possible rhythm disorders – RAAS ⇒ angiotensin ⇒ vasoconstriction and myocardial re-modulation ⇒ ALD ⇒ ↑ reabsorption of Na+ and H2O ⇒ Secondary hyperaldosteronism – ADH ⇒ vasoconstriction and resorption of H2O ...
Cardiac Conduction
Cardiac Conduction

...  AV bundle: a pathway for the AP’s from the AV node to travel through the septum as it splits into R and L branches toward apex of heart  Purkinje fibers: branches of the AV bundle that travel from the apex upward ...
Treatment - Digoxin Immune Fab
Treatment - Digoxin Immune Fab

... artery laceration, and cardiac tamponade may occur. Atropine sulfate is a parasympatholytic drug that increases heart rate and conduction through the atrioventricular node. It is given for asystole (except in children), bradyarrhythmias, and high-degree atrioventricular nodal block, although no surv ...
Current practice of cardiac resynchronization therapy (CRT) in the
Current practice of cardiac resynchronization therapy (CRT) in the

... 11. Holzmeister J, Hurlimann D, Steffel J, Ruschitzka F. Cardiac resynchronization therapy in patients with a narrow QRS. Curr Heart Fail Rep 2009;6:49 –56. 12. Linde C, Abraham WT, Gold MR, St John Sutton M, Ghio S, Daubert C. Randomized trial of cardiac resynchronization in mildly symptomatic hear ...
peripratum heart failure with normal ejection fraction: a novel entity
peripratum heart failure with normal ejection fraction: a novel entity

... with PHFNEF secondary to hypertension (n=9), preeclampsia (n=1) and diabetesmellitus (n=2) yielded 11 patients (Group I). Appropriate age-matched traditional PPCM controls identified during the same time window, formed Group II (n=16). Patients with PHFNEF had significantly lower B-type-natriuretic ...
Anaesthesia and heart failure Introduction: Congestive cardiac
Anaesthesia and heart failure Introduction: Congestive cardiac

... analgesia is important and use of regional techniques should be considered. Epidural infusions obtund the stress response to surgery and can provide effective post-operative analgesia. The haemodynamic effects are potentially favourable. Reducing afterload by vasodilation can greatly reduce myocardi ...
Lucia is an 8 year old girl who is a patient of Dr. Paulson who
Lucia is an 8 year old girl who is a patient of Dr. Paulson who

... Lucia is an 8 year old girl who is a patient of Dr. Paulson who suffered a cardiac arrest in her front yard last spring. Mom did CPR and the police used a defibrillator to get her heart going again. She had an MRI that looked pretty bad and her parents were told she’d never walk or talk again. Howev ...
MANAGEMENT OF RAPID ATRIAL FIBRILLATION IN EMERGENCY
MANAGEMENT OF RAPID ATRIAL FIBRILLATION IN EMERGENCY

... Atrial fibrillation (AF) is identified by a sustained irregularly irregular heart beat and the absence of p waves on the ECG. In most instances the QRS complex will be narrow but as the ventricular response increases the QRS complex may widen due to aberrant conduction. The QRS complexes will also b ...
Cardiac Resynchronization therapy
Cardiac Resynchronization therapy

... Provider Tool Effective Date: 03/09/2012 ...
Lecture Note 3 - Heart Failure
Lecture Note 3 - Heart Failure

... initial stretching of the cardiac myocytes prior to contraction. Myocyte stretching causes an increase in force generation. This mechanism enables the heart to eject the additional venous return, thereby increasing stroke volume. ...
Atrioventricular Reentrant Tachycardia (AVRT)
Atrioventricular Reentrant Tachycardia (AVRT)

... This is a heart rhythm condition in which the heart rate can become abnormally fast This is a type of supraventricular tachycardia (SVT). This is related to an abnormal “short circuit” in the electrical connections of the heart between the atria and the ventricles (heart chambers.) Episodes of fast ...
Heart Failure: A New Epidemic of Cardiovascular Disease
Heart Failure: A New Epidemic of Cardiovascular Disease

... HF in many countries.6 In the original and subsequent Framingham cohort, 62% and 75% of men and 38% and 42% of women, respectively, died within 5 years of being diagnosed with heart failure. Effective treatment has improved both of these outcomes, with a relative reduction in hospitalization in re ...
long qt syndrome - information sheet
long qt syndrome - information sheet

... abnormal electrical activity in the heart. It affects mostly children and young adults with frequent faints or even sudden death. The most common form of LQTS is inherited in a dominant pattern, which means that each child of an affected parent has a 50% chance of inheriting the disorder. Once a dia ...
a new treatment for advanced heart failure ventricular assist devices
a new treatment for advanced heart failure ventricular assist devices

... pumping blood to the body. It does NOT replace the heart. Patients need to have surgery to implant the device. Since VADs help move more oxygen-rich blood, VAD patients often have more energy than before. This means they can resume activities they enjoy. like shopping and visiting family and friends ...
Heart Physiology - Kleins
Heart Physiology - Kleins

... You should understand by now that the Physiology of the Heart refers to the function of the heart You need to be familiar with the conduction system of the heart, the cardiac cycle, sounds of the heart, and cardiac out put ...
CRT-D or CRT-P in CRT-indicated patients?
CRT-D or CRT-P in CRT-indicated patients?

... There was no statistically significant correlation between HRV parameters and 6-minute walking test, functional capacity, right ventricular systolic function, BNP and hs-troponin-I levels. Most common cause of death in these patients is arrhythmia, and autonomic dysfunction may be triggering factor ...
A1985ABD9400001
A1985ABD9400001

... This study gave rise to numerous large clinical trials2 3of vasodilators in acute myocardial infarction, ’ It became an important, frequently cited study because it was innovative and introduced the new concept into clinical practice that perfor. mance of the failing heart could be favorably manipul ...
Heart/Cardiovascular
Heart/Cardiovascular

... Stroke Volume Regulation SV is the difference between EDV (blood in ventricle during diastole) and ESV (blood in ventricle during systole) Normal SV = 70 ml/beat Depends on the following factors ◦ Preload (Frank-Starling Law) ◦ Contractility ◦ Afterload ...
Stem Cells for the Failing Heart
Stem Cells for the Failing Heart

fact sheet - Medtronic
fact sheet - Medtronic

... implantable device to improve the pumping efficiency of the heart and increase blood flow to the body. By improving blood flow, CRT may help to reduce heart failure symptoms, improve quality of life and reduce mortality. CRT is intended to complement standard drug therapy, and dietary and lifestyle ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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