0474 ch 14(281-305).
... Although the heart’s right and left sides are separated from each other, they work together. Blood is squeezed through the chambers by a heart muscle contraction that begins in the thin-walled upper chambers, the atria, and is followed by a contraction of the thick muscle of the lower chambers, the ...
... Although the heart’s right and left sides are separated from each other, they work together. Blood is squeezed through the chambers by a heart muscle contraction that begins in the thin-walled upper chambers, the atria, and is followed by a contraction of the thick muscle of the lower chambers, the ...
2014 ESC Guidelines on diagnosis and management
... Other ESC entities having participated in the development of this document: Associations: European Association of Cardiovascular Imaging (EACVI), European Association of Percutaneous Cardiovascular Interventions (EAPCI), European Heart Rhythm Association (EHRA), Heart Failure Association of the ESC ...
... Other ESC entities having participated in the development of this document: Associations: European Association of Cardiovascular Imaging (EACVI), European Association of Percutaneous Cardiovascular Interventions (EAPCI), European Heart Rhythm Association (EHRA), Heart Failure Association of the ESC ...
Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation
... the derivation of multiple parameters of myocardial function. The goal of this document is to focus on the currently available techniques that allow quantitative assessment of myocardial function via image-based analysis of local myocardial dynamics, including Doppler tissue imaging and speckle-trac ...
... the derivation of multiple parameters of myocardial function. The goal of this document is to focus on the currently available techniques that allow quantitative assessment of myocardial function via image-based analysis of local myocardial dynamics, including Doppler tissue imaging and speckle-trac ...
Full-Text PDF
... Doxorubicin (DOX) belongs to the family of anthracyclines, and has been used to against cancer since late 1960s. It is the most effective anticancer drugs. However, studies of cardiotoxic effects of DOX have been reported [1,2]. Therefore, chemotherapy with DOX is limited by its cardiotoxicity. The ...
... Doxorubicin (DOX) belongs to the family of anthracyclines, and has been used to against cancer since late 1960s. It is the most effective anticancer drugs. However, studies of cardiotoxic effects of DOX have been reported [1,2]. Therefore, chemotherapy with DOX is limited by its cardiotoxicity. The ...
DOI: 10.1161/CIRCULATIONAHA.109.929646 published online May
... Background—Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of ...
... Background—Anecdotal cases of familial clustering of peripartum cardiomyopathy (PPCM) and familial occurrences of PPCM and idiopathic dilated cardiomyopathy (DCM) together have been observed, suggesting that genetic factors play a role in the pathogenesis of PPCM. We hypothesized that some cases of ...
Echocardiographic Estimation of Pulmonary Artery Pressure in
... PEP/LVET of 0.26 or greater would seem to preclude a precise estimate of pulmonary artery pressure from the STI. However, a ratio of PEP/LVET of less than 0.26 was almost invariably associated with low pulmonary pressure. If left ventricular STI are used as a screening test for pulmonary hypertensio ...
... PEP/LVET of 0.26 or greater would seem to preclude a precise estimate of pulmonary artery pressure from the STI. However, a ratio of PEP/LVET of less than 0.26 was almost invariably associated with low pulmonary pressure. If left ventricular STI are used as a screening test for pulmonary hypertensio ...
Effect of healthy aging on left ventricular relaxation and - AJP
... metroplex and a diverse health care company. All subjects were nonsmokers, were not taking any cardiovascular medications, had a 24-h blood pressure ⬍140/90 mmHg, body mass index ⱕ30 kg/m2, and had a normal electrocardiogram and exercise stress echocardiogram. Subjects were either sedentary or casua ...
... metroplex and a diverse health care company. All subjects were nonsmokers, were not taking any cardiovascular medications, had a 24-h blood pressure ⬍140/90 mmHg, body mass index ⱕ30 kg/m2, and had a normal electrocardiogram and exercise stress echocardiogram. Subjects were either sedentary or casua ...
murmurs
... Common defects that cause murmurs include: Congenital septal defects, which are holes in the wall (septum) that separates the right and left sides of the heart. They account for more than half of abnormal murmurs in children. Congenital valve defects, which include narrow valves that do not allo ...
... Common defects that cause murmurs include: Congenital septal defects, which are holes in the wall (septum) that separates the right and left sides of the heart. They account for more than half of abnormal murmurs in children. Congenital valve defects, which include narrow valves that do not allo ...
3D anatomical modelling of the human cardiac conduction system
... A detailed understanding of the anatomy of the cardiac conduction system is important in understanding its functioning and potential role in arrhythmogenesis. The creation of 3D models is an increasingly important field as they are powerful tools and have many potentially valuable educational, resea ...
... A detailed understanding of the anatomy of the cardiac conduction system is important in understanding its functioning and potential role in arrhythmogenesis. The creation of 3D models is an increasingly important field as they are powerful tools and have many potentially valuable educational, resea ...
Diabetic Cardiomyopathy
... A) Fibrotic infiltration in the myocardium with Masson's trichrome staining. Area stained blue represent fibrotic infiltration. Magnification at 200×, scale bar is 100 μm. B) Quantitative analysis of fibrosis. The collagen volume fraction was higher in the diabetic group than in the control group ...
... A) Fibrotic infiltration in the myocardium with Masson's trichrome staining. Area stained blue represent fibrotic infiltration. Magnification at 200×, scale bar is 100 μm. B) Quantitative analysis of fibrosis. The collagen volume fraction was higher in the diabetic group than in the control group ...
Mayo Clinic Cardiology Board - Review Questions and Answers
... T. Jared Bunch, MD, is from Logan, Utah. He graduated from Utah State University with undergraduate degrees in chemistry, liberal arts, and sciences. He received his MD from the University of Utah. He completed a residency in internal medicine and a fellowship in cardiovascular diseases and is curre ...
... T. Jared Bunch, MD, is from Logan, Utah. He graduated from Utah State University with undergraduate degrees in chemistry, liberal arts, and sciences. He received his MD from the University of Utah. He completed a residency in internal medicine and a fellowship in cardiovascular diseases and is curre ...
Percentage of Left Ventricular
... and the aortic valve area in cm2 and cm2/m2 was - 0.79 and - 0.80, respectively (fig. 2). With five exceptions (cases 5, 6, 9, 10, and 47), patients who had aortic valve areas of 1.0 cm2 or less had greater than 30% left ventricular stroke work loss, and with two exceptions (cases 9 and 47) patients ...
... and the aortic valve area in cm2 and cm2/m2 was - 0.79 and - 0.80, respectively (fig. 2). With five exceptions (cases 5, 6, 9, 10, and 47), patients who had aortic valve areas of 1.0 cm2 or less had greater than 30% left ventricular stroke work loss, and with two exceptions (cases 9 and 47) patients ...
Guidelines and Standards for Performance of a Pediatric
... The video screen and display should be of suitable size and quality for observation and interpretation of all the above modalities. The display should identify the parent institution, a patient identifier, and the date and time of the study. The electrocardiogram should also be displayed in real tim ...
... The video screen and display should be of suitable size and quality for observation and interpretation of all the above modalities. The display should identify the parent institution, a patient identifier, and the date and time of the study. The electrocardiogram should also be displayed in real tim ...
Effect of changes in contractility on the index of myocardial
... Digoxin, an oral inotropic agent, also has beneficial symptomatic effects in heart failure patients with either reduced or preserved LV function [11]. However, the influence of digoxin on IMP is unknown and may provide some insight into its efficacy. The goals of this study were: [1] to determine th ...
... Digoxin, an oral inotropic agent, also has beneficial symptomatic effects in heart failure patients with either reduced or preserved LV function [11]. However, the influence of digoxin on IMP is unknown and may provide some insight into its efficacy. The goals of this study were: [1] to determine th ...
Full Paper - Daniel Burkhoff MD PhD
... Representative pressure and calcium transients measured during steady-state ejecting beats and on the first isovolumic beat of variously timed volume clamps are shown in Fig. 2. As shown in Fig. 2D, there is an approximately linear relationship (dotted line) between peak pressure and volume on the t ...
... Representative pressure and calcium transients measured during steady-state ejecting beats and on the first isovolumic beat of variously timed volume clamps are shown in Fig. 2. As shown in Fig. 2D, there is an approximately linear relationship (dotted line) between peak pressure and volume on the t ...
Demonstration of Coronary-Pulmonary Artery Fistula with Saccular
... from the coronary steal phenomenon). Frank congestive heart failure is a frequent complication, especially in patients above 40 years of age; however other complications such as arrhythmias, infective endocarditis, rupture of an aneurismal fistula, and sudden death have been described [5]. Until rec ...
... from the coronary steal phenomenon). Frank congestive heart failure is a frequent complication, especially in patients above 40 years of age; however other complications such as arrhythmias, infective endocarditis, rupture of an aneurismal fistula, and sudden death have been described [5]. Until rec ...
Guidelines and Standards for Performance of a Pediatric
... The video screen and display should be of suitable size and quality for observation and interpretation of all the above modalities. The display should identify the parent institution, a patient identifier, and the date and time of the study. The electrocardiogram should also be displayed in real tim ...
... The video screen and display should be of suitable size and quality for observation and interpretation of all the above modalities. The display should identify the parent institution, a patient identifier, and the date and time of the study. The electrocardiogram should also be displayed in real tim ...
1 Cold acclimation increases cardiac myofilament function and
... Cold acclimation increases cardiac myofilament function and ventricular pressure generation in trout ...
... Cold acclimation increases cardiac myofilament function and ventricular pressure generation in trout ...
European Journal of Preventive Cardiology
... The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity, cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. H ...
... The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity, cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. H ...
Aortic stiffness and valvular calcifications in patients with end
... a common etiology. As demonstrated, the chronic renal failure and worse aortic elasticity patients subgroup is characterized by simultaneous greater aortic valve leaflet damage, reflected by their more extensive calcification. It does not apply to the aortic valve annulus or the mitral valve leaflet ...
... a common etiology. As demonstrated, the chronic renal failure and worse aortic elasticity patients subgroup is characterized by simultaneous greater aortic valve leaflet damage, reflected by their more extensive calcification. It does not apply to the aortic valve annulus or the mitral valve leaflet ...
the relationship between electrical and mechanical - Heart
... In some instances a double lumen catheter was used (Cournand et al., 1945), permitting the simultaneous recording of pressures in the right auricle and ventricle or the right ventricle and pulmonary artery. In order to obtain satisfactory records of these pressures, manometers of varying sensitiviti ...
... In some instances a double lumen catheter was used (Cournand et al., 1945), permitting the simultaneous recording of pressures in the right auricle and ventricle or the right ventricle and pulmonary artery. In order to obtain satisfactory records of these pressures, manometers of varying sensitiviti ...
Sequential growth of fetal sheep cardiac myocytes in response to
... increase myocardial mass (6, 7, 10). It is unknown if the growth of these loaded hearts occurs by increased myocyte proliferation or by myocyte enlargement. Adult hearts typically respond to increases in hemodynamic load in a predictable manner by a combination of myocyte enlargement and ventricular ...
... increase myocardial mass (6, 7, 10). It is unknown if the growth of these loaded hearts occurs by increased myocyte proliferation or by myocyte enlargement. Adult hearts typically respond to increases in hemodynamic load in a predictable manner by a combination of myocyte enlargement and ventricular ...
Depolarization and Repolarization
... of >1mm and longer than 80 milliseconds following the Jpoint. This measure has a false positive rate of 15-20% (which is slightly higher in women than men) and a false negative rate of 20-30%. • ST depression may be associated with hypokalemia or digitalis toxicity. ...
... of >1mm and longer than 80 milliseconds following the Jpoint. This measure has a false positive rate of 15-20% (which is slightly higher in women than men) and a false negative rate of 20-30%. • ST depression may be associated with hypokalemia or digitalis toxicity. ...
Current and Evolving Echocardiographic Techniques
... the derivation of multiple parameters of myocardial function. The goal of this document is to focus on the currently available techniques that allow quantitative assessment of myocardial function via image-based analysis of local myocardial dynamics, including Doppler tissue imaging and speckle-trac ...
... the derivation of multiple parameters of myocardial function. The goal of this document is to focus on the currently available techniques that allow quantitative assessment of myocardial function via image-based analysis of local myocardial dynamics, including Doppler tissue imaging and speckle-trac ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.