Attila Borbély, Loek van Heerebeek and Walter J. Paulus 2009, 104:12-14
... corroborated by in vitro shifts in titin isoform expression observed in primary cardiomyocyte cultures prepared from embryonic rats.7 In these cultures, the shift from the fetal compliant N2BA titin isoform to the adult stiff N2B titin isoform depended on matrix stiffness as it differed between flex ...
... corroborated by in vitro shifts in titin isoform expression observed in primary cardiomyocyte cultures prepared from embryonic rats.7 In these cultures, the shift from the fetal compliant N2BA titin isoform to the adult stiff N2B titin isoform depended on matrix stiffness as it differed between flex ...
The Diagnostic Value of 3D Wall Motion Tracking in the Assessment
... In this study we examined a population of healthy volunteers and patients with different heart diseases. We would like to present a case of a young heart transplant patient. The patient presented with re peated cardiac decompensations accompanied by progressive weight gain and progressive dyspnoea ...
... In this study we examined a population of healthy volunteers and patients with different heart diseases. We would like to present a case of a young heart transplant patient. The patient presented with re peated cardiac decompensations accompanied by progressive weight gain and progressive dyspnoea ...
Spontaneous baroreflex control of cardiac output during dynamic
... Although the spontaneous baroreflex HR technique has often been used to study baroreflex control of HR (2, 3, 14, 23, 29), Sala-Mercado et al. (33a) in the accompanying article have shown that these baroreflex-mediated changes in HR do not always cause changes in cardiac output (CO) due to changes i ...
... Although the spontaneous baroreflex HR technique has often been used to study baroreflex control of HR (2, 3, 14, 23, 29), Sala-Mercado et al. (33a) in the accompanying article have shown that these baroreflex-mediated changes in HR do not always cause changes in cardiac output (CO) due to changes i ...
Downloaded - VU-dare
... corroborated by in vitro shifts in titin isoform expression observed in primary cardiomyocyte cultures prepared from embryonic rats.7 In these cultures, the shift from the fetal compliant N2BA titin isoform to the adult stiff N2B titin isoform depended on matrix stiffness as it differed between flex ...
... corroborated by in vitro shifts in titin isoform expression observed in primary cardiomyocyte cultures prepared from embryonic rats.7 In these cultures, the shift from the fetal compliant N2BA titin isoform to the adult stiff N2B titin isoform depended on matrix stiffness as it differed between flex ...
Neurocardiogenic Syncope
... Class IIb 1) Patients with episodic shortness of breath, chest pain hat that is not otherwise explained 2) Patient with neurological events when transientatrial fibrillation or flutter is suspected 3) Patients with symptoms such as syncope, near syncope, episodic dizziness, or palpitation in whom a ...
... Class IIb 1) Patients with episodic shortness of breath, chest pain hat that is not otherwise explained 2) Patient with neurological events when transientatrial fibrillation or flutter is suspected 3) Patients with symptoms such as syncope, near syncope, episodic dizziness, or palpitation in whom a ...
Systolic and Diastolic Heart Failure
... Systolic and Diastolic Heart Failure Cardiology Devision Othmane Taha ...
... Systolic and Diastolic Heart Failure Cardiology Devision Othmane Taha ...
Self Assessment CME Treatment of Aortic Valve Stenosis
... Aortic Valve Stenosis is a progressive disease, which on average, the valve area decreases by approximately 0.1cm2 per year. Signs or symptoms usually present with a valve area of 1cm2 or less. The presence of symptoms (angina pectoris, CHF, syncope, or sudden death) with a diminished valve area is ...
... Aortic Valve Stenosis is a progressive disease, which on average, the valve area decreases by approximately 0.1cm2 per year. Signs or symptoms usually present with a valve area of 1cm2 or less. The presence of symptoms (angina pectoris, CHF, syncope, or sudden death) with a diminished valve area is ...
Mitral Valve Prolapse is a Frequent Cardiovascular
... of mitral valve prolapse. The association of mitral valve prolapse with anorexia nervosa has been known for a long time.2-9 Taking into account the pathophysiology of mitral valve prolapse makes it easy to understand this frequent finding. According to the valvular-ventricular disproportion theory10 ...
... of mitral valve prolapse. The association of mitral valve prolapse with anorexia nervosa has been known for a long time.2-9 Taking into account the pathophysiology of mitral valve prolapse makes it easy to understand this frequent finding. According to the valvular-ventricular disproportion theory10 ...
Research MSc2
... spectacular achievements. The young competitor is not exempt and often the pinnacle of sporting and athletic achievement is being won at an ever younger age. Society and the media consider exercise a benefit for all and encouragement to undertake regular physical activity is endorsed by the medical ...
... spectacular achievements. The young competitor is not exempt and often the pinnacle of sporting and athletic achievement is being won at an ever younger age. Society and the media consider exercise a benefit for all and encouragement to undertake regular physical activity is endorsed by the medical ...
Libby: Braunwald`s Heart Disease: A Textbook of Cardiovascular
... Patients with chronic obstructive pulmonary disease and this electrocardiographic pattern have more severe pulmonary dysfunction, as well as significantly reduced survival. However, comparison of electrocardiographic and hemodynamic parameters has not demonstrated a close correlation of P wave patte ...
... Patients with chronic obstructive pulmonary disease and this electrocardiographic pattern have more severe pulmonary dysfunction, as well as significantly reduced survival. However, comparison of electrocardiographic and hemodynamic parameters has not demonstrated a close correlation of P wave patte ...
Differences in Sarcoplasmic Reticulum Ca2+ Leak Characteristics
... Data are shown as means ± SD. HR, heart rate; ASBP, aortic systolic blood pressure; ADBP, aortic diastolic blood pressure; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end diastolic pressure; LV dp/dtmax, first derivatives of left ventricular value of systolic and end-diastolic ...
... Data are shown as means ± SD. HR, heart rate; ASBP, aortic systolic blood pressure; ADBP, aortic diastolic blood pressure; LVSP, left ventricular systolic pressure; LVEDP, left ventricular end diastolic pressure; LV dp/dtmax, first derivatives of left ventricular value of systolic and end-diastolic ...
Focused transesophageal echocardiography for emergency
... with very good success rates on a high-fidelity simulator. In instructing EPs to apply this TEE protocol, high levels of success with acquisition of the four views were found in the majority of participants in both the immediate post-workshop evaluation (82.1 % views successful) and the retention an ...
... with very good success rates on a high-fidelity simulator. In instructing EPs to apply this TEE protocol, high levels of success with acquisition of the four views were found in the majority of participants in both the immediate post-workshop evaluation (82.1 % views successful) and the retention an ...
Special Report
... Abstract—The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29, 2008, to identify gaps and recommend research strategies to prevent atrial fibrillation (AF). The panel reviewed the existing basic scientific, epidemiological, and clinical literature about AF and identi ...
... Abstract—The National Heart, Lung, and Blood Institute convened an expert panel April 28 to 29, 2008, to identify gaps and recommend research strategies to prevent atrial fibrillation (AF). The panel reviewed the existing basic scientific, epidemiological, and clinical literature about AF and identi ...
NEW DEVELOPMENTS iN ECHOCARDiOGRAPHy
... quality is of prime importance. Obtaining high-quality images, especially at peak stress, can be extremely difficult in many patients, and contrast-enhanced imaging is required in at least 75% of patients during stress echo. Plana et al5 have shown that the use of contrast agents during dobutamine ...
... quality is of prime importance. Obtaining high-quality images, especially at peak stress, can be extremely difficult in many patients, and contrast-enhanced imaging is required in at least 75% of patients during stress echo. Plana et al5 have shown that the use of contrast agents during dobutamine ...
Progression from hypertrophic to dilated cardiomyopathy in mice
... were genotyped by PCR and allowed to reach 8–11 mo of age under identical conditions, when some of the mice were selected for noninvasive echocardiography and exercise testing. Separate groups of age-matched male mice were euthanized for isolated heart experiments, histology, pharmacology, or RNA ex ...
... were genotyped by PCR and allowed to reach 8–11 mo of age under identical conditions, when some of the mice were selected for noninvasive echocardiography and exercise testing. Separate groups of age-matched male mice were euthanized for isolated heart experiments, histology, pharmacology, or RNA ex ...
PEEP and cardiac output
... a basic mechanism leading to ventilator-induced lung injury [1]. To prevent alveolar cycling and derecruitment in acute lung injury, high levels of PEEP have been found necessary to counterbalance the increased lung mass resulting from oedema, inflammation and infiltrations and to maintain normal fu ...
... a basic mechanism leading to ventilator-induced lung injury [1]. To prevent alveolar cycling and derecruitment in acute lung injury, high levels of PEEP have been found necessary to counterbalance the increased lung mass resulting from oedema, inflammation and infiltrations and to maintain normal fu ...
Acute Effects of Right Ventricular Apical Pacing on Left Ventricular
... and twist, using 2D speckle-tracking strain imaging. Methods and Results—A group of 25 patients with structural normal hearts referred for electrophysiological study were studied. Two-dimensional echocardiography was performed at baseline and during RV apical pacing at the time of the electrophysiol ...
... and twist, using 2D speckle-tracking strain imaging. Methods and Results—A group of 25 patients with structural normal hearts referred for electrophysiological study were studied. Two-dimensional echocardiography was performed at baseline and during RV apical pacing at the time of the electrophysiol ...
BAYLOR HEART AND VASCULAR SERVICES AT DALLAS
... compassion, honesty, transparency, and patient-centered care, our board of managers, leadership team and staff came together as one to achieve some of the biggest milestones in the history of Baylor Jack and Jane Hamilton Heart and Vascular Hospital. In March, we received the 2014 Texas Award for Pe ...
... compassion, honesty, transparency, and patient-centered care, our board of managers, leadership team and staff came together as one to achieve some of the biggest milestones in the history of Baylor Jack and Jane Hamilton Heart and Vascular Hospital. In March, we received the 2014 Texas Award for Pe ...
Clinical use of ultrashort-lived radionuclide krypton-81m for
... count maximum in the end-diastolic image. Right ventricular ejection fraction was calculated by subtracting endsystolic from end-diastolic counts divided by end-diastolic counts x 100. No background correction was performed. To test both methods (krypton-81 m ventriculography and contrast cineangiog ...
... count maximum in the end-diastolic image. Right ventricular ejection fraction was calculated by subtracting endsystolic from end-diastolic counts divided by end-diastolic counts x 100. No background correction was performed. To test both methods (krypton-81 m ventriculography and contrast cineangiog ...
a Patient`s Guide to Transcatheter Aortic
... Warnings Some patients may have a disease that results in more calcium in their blood. This may cause early wear. The Medtronic TAVR valve is only for certain patients. This includes patients with severe AS or failing surgical valves that: · Cannot have surgery · Are at high risk for surgery ...
... Warnings Some patients may have a disease that results in more calcium in their blood. This may cause early wear. The Medtronic TAVR valve is only for certain patients. This includes patients with severe AS or failing surgical valves that: · Cannot have surgery · Are at high risk for surgery ...
Syncope - Royal College of Emergency Medicine
... This group should be further evaluated in the ED on a monitored bed. IP referral is suggested by P<50 at any time, PR bleed, Hb<10 gm/d, chest pain, ECG showing new Q wave in any lead but III, SpO2 < 94% air, new dyspnoea, age > 65 (with no clear diagnosis and no prodrome) and any patient in whom si ...
... This group should be further evaluated in the ED on a monitored bed. IP referral is suggested by P<50 at any time, PR bleed, Hb<10 gm/d, chest pain, ECG showing new Q wave in any lead but III, SpO2 < 94% air, new dyspnoea, age > 65 (with no clear diagnosis and no prodrome) and any patient in whom si ...
PDF - World Wide Journals
... T: XVIII. Persistent fetal dispersion of the atrioventricular node and His bundle within the central fibrous body.Circulation 1976, 53(6):1026-1034. | 11. Rose M, Gross L, Protos A: Transvenous pacemaker implanta- tion by way of an anomalous left superior vena cava. J Thorac Cardiovasc Surg 1971, 62 ...
... T: XVIII. Persistent fetal dispersion of the atrioventricular node and His bundle within the central fibrous body.Circulation 1976, 53(6):1026-1034. | 11. Rose M, Gross L, Protos A: Transvenous pacemaker implanta- tion by way of an anomalous left superior vena cava. J Thorac Cardiovasc Surg 1971, 62 ...
Taurine depletion caused by knocking out the taurine transporter
... impaired Ca2+ sensitivity of the myofibrils can lead to the development of heart failure. Second, it possesses antioxidant [11–13] and anti-apoptotic activity [15,16], which would be expected to limit ventricular remodeling. Finally, taurine is a key osmoregulator in the heart [13], an action that s ...
... impaired Ca2+ sensitivity of the myofibrils can lead to the development of heart failure. Second, it possesses antioxidant [11–13] and anti-apoptotic activity [15,16], which would be expected to limit ventricular remodeling. Finally, taurine is a key osmoregulator in the heart [13], an action that s ...
The ultrasound detection of chromosomal anomalies
... Cardiac anomalies are very common: 85 per 10,000 newborn will have a cardiac anomaly. But among the fetuses that have aneuploidy, the association is even more dramatic: 99 percent of fetuses with trisomy 18 have cardiac anomaly. Ninety percent of trisomy 13, 50 percent of trisomy 21 etc… therefore t ...
... Cardiac anomalies are very common: 85 per 10,000 newborn will have a cardiac anomaly. But among the fetuses that have aneuploidy, the association is even more dramatic: 99 percent of fetuses with trisomy 18 have cardiac anomaly. Ninety percent of trisomy 13, 50 percent of trisomy 21 etc… therefore t ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.