A Cure for the Code Blues? Vasopressin, Steroid and Epinephrine
... OHCA: out-of-hospital cardiac arrest; EPI: epinephrine; mg: milligram; min: minute(s); VASO: vasopressin; ROSC: return of spontaneous circulation; ER: emergency room; DB: double blind; RCT: randomized controlled trial; petCO2: end-tidal carbon dioxide; hr: hour; MC: multicentered; mcg: micrograms; B ...
... OHCA: out-of-hospital cardiac arrest; EPI: epinephrine; mg: milligram; min: minute(s); VASO: vasopressin; ROSC: return of spontaneous circulation; ER: emergency room; DB: double blind; RCT: randomized controlled trial; petCO2: end-tidal carbon dioxide; hr: hour; MC: multicentered; mcg: micrograms; B ...
Coronary Sinus-Still a Potential Site for Research
... annular size. Three safety and efficacy studies were carried out in Europe: AMADEUS (CARILLON Mitral Annuloplasty Device European Union Study), TITAN, and TITAN II [19]. All subjects had to have symptomatic congestive heart failure, New York Heart Association classification (NYHA) 2 to 4, 6 minute w ...
... annular size. Three safety and efficacy studies were carried out in Europe: AMADEUS (CARILLON Mitral Annuloplasty Device European Union Study), TITAN, and TITAN II [19]. All subjects had to have symptomatic congestive heart failure, New York Heart Association classification (NYHA) 2 to 4, 6 minute w ...
Syncope Iowa State University
... A fall in cardiac output or vascular resistance reduces mean arterial pressure and consequently, cerebral perfusion. Syncope occurs when cerebral blood flow falls below 30–50% of normal. Symptoms of pre-syncope can occur with less severe hemodynamic changes.3 Syncope in dogs and cats, is often assoc ...
... A fall in cardiac output or vascular resistance reduces mean arterial pressure and consequently, cerebral perfusion. Syncope occurs when cerebral blood flow falls below 30–50% of normal. Symptoms of pre-syncope can occur with less severe hemodynamic changes.3 Syncope in dogs and cats, is often assoc ...
Asynchronous Atrioventricular Valve Opening as it Relates
... heart disease was the usual indication for the echocardiogram. All babies were subsequently proved not to have heart disease by echocardiography and follow-up clinical examination. All studies were performed in conformity with established rules regarding clinical investigation of the Institutional R ...
... heart disease was the usual indication for the echocardiogram. All babies were subsequently proved not to have heart disease by echocardiography and follow-up clinical examination. All studies were performed in conformity with established rules regarding clinical investigation of the Institutional R ...
Role of Pacing in Neurally Mediated Syncope
... only The great success of the initial studies raised the possibility a placebo effect with implant of a pacemaker for treatment of vasovagal syncope. Hence the first randomized, multicenter, double blinded study was designed and completed. VPS II, in which all 100 patients received pacemakers but we ...
... only The great success of the initial studies raised the possibility a placebo effect with implant of a pacemaker for treatment of vasovagal syncope. Hence the first randomized, multicenter, double blinded study was designed and completed. VPS II, in which all 100 patients received pacemakers but we ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... morbidity and mortality in humans. MI related complications such as heart failure are of great socio-economic burdens to society and healthcare systems [1]. Till now, no single mechanism that could fully explain the development of post MI depressed cardiac function and development of HF. It is likel ...
... morbidity and mortality in humans. MI related complications such as heart failure are of great socio-economic burdens to society and healthcare systems [1]. Till now, no single mechanism that could fully explain the development of post MI depressed cardiac function and development of HF. It is likel ...
Melissa Swinnen, Davy Vanhoutte, Geert C. Van Almen, Nazha Hamdani,... W.M. Schellings, Jan D'hooge, Jolanda Van der Velden, Matthew S.... Absence of Thrombospondin-2 Causes Age-Related Dilated Cardiomyopathy
... Background—The progressive shift from a young to an aged heart is characterized by alterations in the cardiac matrix. The present study investigated whether the matricellular protein thrombospondin-2 (TSP-2) may affect cardiac dimensions and function with physiological aging of the heart. Methods an ...
... Background—The progressive shift from a young to an aged heart is characterized by alterations in the cardiac matrix. The present study investigated whether the matricellular protein thrombospondin-2 (TSP-2) may affect cardiac dimensions and function with physiological aging of the heart. Methods an ...
Syncope - American College of Physicians
... Simpson CS, Krahn AD, Klein GJ, Yee R, Skanes AC, Manda V, Norris C. A cost effective approach to the investigation of syncope: relative merit of different diagnostic strategies. Can J Cardiol 1999;15(5):579-84. Strickberger, SA, Benson DW, Biaggioni I, Callans DJ, Cohen MI, Ellenbogen KA, et al. AH ...
... Simpson CS, Krahn AD, Klein GJ, Yee R, Skanes AC, Manda V, Norris C. A cost effective approach to the investigation of syncope: relative merit of different diagnostic strategies. Can J Cardiol 1999;15(5):579-84. Strickberger, SA, Benson DW, Biaggioni I, Callans DJ, Cohen MI, Ellenbogen KA, et al. AH ...
pericardial effusions by echocardiography - Heart
... to the aortic root and left atrium (Fig. 2A). Only a narrow echo-free space, wider in systole than in diastole, is visualised between the ventricular posterior wall and parietal pericardium at mid left ventricular level. This echo-free space widens considerably (to about 1-5 cm) behind the basal lef ...
... to the aortic root and left atrium (Fig. 2A). Only a narrow echo-free space, wider in systole than in diastole, is visualised between the ventricular posterior wall and parietal pericardium at mid left ventricular level. This echo-free space widens considerably (to about 1-5 cm) behind the basal lef ...
Sudden Cardiac Death in the Young
... or news media review.20 This introduces ascertainment uncertainty with respect to both over- and underdiagnosis. A prospective analysis of SCD in patients of all ages suggested that ascertainment based on death certificates tended to overestimate SCD events.21 Case series of SCD allow excellent asce ...
... or news media review.20 This introduces ascertainment uncertainty with respect to both over- and underdiagnosis. A prospective analysis of SCD in patients of all ages suggested that ascertainment based on death certificates tended to overestimate SCD events.21 Case series of SCD allow excellent asce ...
Lifestyle management to prevent and treat atrial fibrillation
... Additionally, every 5-unit increase in BMI was significantly associated with a 10% increase in postoperative AF and 13% increase in post-ablation AF, respectively [36]. In obese subjects, increased left atrial pressure and volume as well as shortening of the effective refractory period have been fou ...
... Additionally, every 5-unit increase in BMI was significantly associated with a 10% increase in postoperative AF and 13% increase in post-ablation AF, respectively [36]. In obese subjects, increased left atrial pressure and volume as well as shortening of the effective refractory period have been fou ...
Effect of Altitude on the Heart and the Lungs
... Chronic right ventricular pressure overload may play a part in reducing left ventricular stroke volume. Pericardial constraint modulates the ventricular stroke volumes.25 When the right ventricle dilates in response to increased pulmonary vascular resistance, the left ventricular diastolic volume is ...
... Chronic right ventricular pressure overload may play a part in reducing left ventricular stroke volume. Pericardial constraint modulates the ventricular stroke volumes.25 When the right ventricle dilates in response to increased pulmonary vascular resistance, the left ventricular diastolic volume is ...
2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline
... disease. The focus is on medical practice in the United States, but guidelines developed in collaboration with other organizations may have a global impact. Although guidelines may be used to inform regulatory or payer decisions, their intent is to improve patients’ quality of care and align with pa ...
... disease. The focus is on medical practice in the United States, but guidelines developed in collaboration with other organizations may have a global impact. Although guidelines may be used to inform regulatory or payer decisions, their intent is to improve patients’ quality of care and align with pa ...
NIH Public Access - Scientific Computing and Imaging Institute
... generator positioned in the anterolateral axillary line in the sixth intercostal space, paired with a parasternal electrode ~3 cm left of the sternal midline. Electrode length has not been specified. We modeled this configuration as depicted in Figure 3 (right panel) and varied the length and positi ...
... generator positioned in the anterolateral axillary line in the sixth intercostal space, paired with a parasternal electrode ~3 cm left of the sternal midline. Electrode length has not been specified. We modeled this configuration as depicted in Figure 3 (right panel) and varied the length and positi ...
Review Article Acute pulmonary oedema in pregnant women A. T. Dennis
... vated end-diastolic pressure and impaired left ventricular filling [25]. The associated elevated pulmonary venous pressure at rest reduces lung compliance, increases the work of breathing and results in the subjective feeling of breathlessness. These symptoms are made worse by exercise [26]. With res ...
... vated end-diastolic pressure and impaired left ventricular filling [25]. The associated elevated pulmonary venous pressure at rest reduces lung compliance, increases the work of breathing and results in the subjective feeling of breathlessness. These symptoms are made worse by exercise [26]. With res ...
Which of the following patients would MOST likely present with
... up into the systemic circulation. Left heart failure typically presents with shortness of breath due to fluid in the lungs (pulmonary edema), which indicates blood backing up from the left side of the heart into the lungs. In severe pulmonary edema, the patient may cough up pink, frothy sputum. Righ ...
... up into the systemic circulation. Left heart failure typically presents with shortness of breath due to fluid in the lungs (pulmonary edema), which indicates blood backing up from the left side of the heart into the lungs. In severe pulmonary edema, the patient may cough up pink, frothy sputum. Righ ...
Characterization and Modeling of the Purkinje System for Biophysical Simulations
... its branches [7, 58, 100, 148, 167]. To visualize the net structure it is necessary to apply sub-endocardial injections of ink or stains. It is very difficult to observe the Purkinje-net system in humans, because these fibres do not stain well. Ex-vivo histological and microscopy animal data of the ...
... its branches [7, 58, 100, 148, 167]. To visualize the net structure it is necessary to apply sub-endocardial injections of ink or stains. It is very difficult to observe the Purkinje-net system in humans, because these fibres do not stain well. Ex-vivo histological and microscopy animal data of the ...
Obstructive Coronary Atherosclerosis and Ischemic Heart
... Coronary Stenosis and Myocardial Ischemia: Re-Examining the Link ...
... Coronary Stenosis and Myocardial Ischemia: Re-Examining the Link ...
Percutaneous mitral valve repair: an overview of new interventional
... Evalve MitraClip® system The MitraClip system utilizes a clip with a coaxial catheter system. The tip of the outer guide catheter is delivered to the left atrium utilizing a standard trans-septal approach. The guide catheter is 24-French proximally, and tapers to 22-French at the point where it cros ...
... Evalve MitraClip® system The MitraClip system utilizes a clip with a coaxial catheter system. The tip of the outer guide catheter is delivered to the left atrium utilizing a standard trans-septal approach. The guide catheter is 24-French proximally, and tapers to 22-French at the point where it cros ...
Haemodynamic and structural correlates of the first and
... with suspected or established PAH are referred for haemodynamic assessment. Consecutive patients referred for right-heart catheterisation (RHC) between November 2010 and July 2011 were invited to participate. Exclusion criteria included the echocardiographic determination of LV systolic dysfunction ...
... with suspected or established PAH are referred for haemodynamic assessment. Consecutive patients referred for right-heart catheterisation (RHC) between November 2010 and July 2011 were invited to participate. Exclusion criteria included the echocardiographic determination of LV systolic dysfunction ...
Coronary Artery Disease (CAD) Secondary Prevention
... Increase KP regions’ abilities to leverage clinical guidelines to improve clinical outcomes. ...
... Increase KP regions’ abilities to leverage clinical guidelines to improve clinical outcomes. ...
Article - Johns Hopkins Medicine
... a history of supraventricular tachycardia, and the other (30) excluded patients taking amiodarone. Appendix Table 1 and Appendix Table 2 (available at www.annals.org) describe the cohorts of each study in greater detail. Compared with placebo, amiodarone decreased the incidence of atrial fibrillatio ...
... a history of supraventricular tachycardia, and the other (30) excluded patients taking amiodarone. Appendix Table 1 and Appendix Table 2 (available at www.annals.org) describe the cohorts of each study in greater detail. Compared with placebo, amiodarone decreased the incidence of atrial fibrillatio ...
ELECTROCARDIOGRAPHY
... is an evidence of perfect nervous and humoral regulation. Regulation of the heart activity is fascinating. Detailed study of the heart physiology clearly points out the perfection of this phenomenon at one side, but also a complexity of it at the other side. Complexity of this regulation may be also ...
... is an evidence of perfect nervous and humoral regulation. Regulation of the heart activity is fascinating. Detailed study of the heart physiology clearly points out the perfection of this phenomenon at one side, but also a complexity of it at the other side. Complexity of this regulation may be also ...
Cardiac contractility modulation
.jpg?width=300)
Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.