• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Atrial Flutter after Coronary Artery Bypass Grafting
Atrial Flutter after Coronary Artery Bypass Grafting

... main independent predictor of postoperative atrial fibrillation in patients undergoing coronary revascularization. Preoperative factors Age is consistently the independent factor most strongly associated with postoperative atrial fibrillation.1,2) Age associated changes in the atria, such as dilatat ...
PDF Article
PDF Article

... New Jersey. The Bristol-Myers Squibb (Plainsboro, New Jersey)/Sanofi Pharmaceuticals (New York, New York) Partnership provided additional funding support. Manuscript received May 18, 2005; revised manuscript received July 24, 2005, accepted August 1, 2005. ...
Print - Circulation Research
Print - Circulation Research

... from this cannula through the extracorporeal probe of an electromagnetic flowmeter (Biotronix) and was returned via the right external jugular vein. Right ventricular force was recorded by a Walton-Brodie strain gauge arch sutured about halfway between the apex and base of the heart and about I or 2 ...
Progression of mitral regurgitation
Progression of mitral regurgitation

... Patients. Inclusion criteria were patients: 1) with isolated organic MR, as defined by two-dimensional echocardiography; 2) with at least a mild degree of regurgitation at baseline; 3) with quantitation of MR performed by one of the authors and using at least two methods simultaneously; and 4) who a ...
the advantages of carvedilol in coronary artery disease
the advantages of carvedilol in coronary artery disease

... infarction (AIM). The aim of the therapy in AIM is to achieve, as early as possible, the reperfusion of infarctrelated artery (by thrombolysis), retain its passability (by anticoagulant and antiaggregation therapy) as well as to maximally limit the size of the infarction. Beta blockers applied in ea ...
Oxygen therapy for acute myocardial infarction (Review) The Cochrane Library
Oxygen therapy for acute myocardial infarction (Review) The Cochrane Library

... breathe. We looked for the evidence to support this practice by searching for randomised controlled trials that compared the outcomes in patients given oxygen to the outcomes for patients given normal air to breathe. We were primarily interested in seeing whether there was a difference in the number ...
Cardiovascular Defects Associated With Abnormalities in Midline
Cardiovascular Defects Associated With Abnormalities in Midline

... and b, ErbB3 expression in migrating neural crest cells of Lp/⫹ (a) and Lp/Lp (b) littermate at E10.5. Robust neural crest cell migration can be observed in aortic arches 3, 4, and 6 in both embryos (arrowheads). Expression can also be seen in the developing dorsal root ganglia (drg, arrows) and in ...
Case Report Congenital Complete Atrioventricular Block
Case Report Congenital Complete Atrioventricular Block

... the deleterious effect of right ventricular pacing is still in debate [3, 4]. This sets the discussion on when is the ideal time for pacemaker implantation. Indications for pacemaker implantation are the presence of symptoms, including exercise intolerance, slow ventricular escape rhythms, and previo ...
Insight into Pulmonary Arterial Hypertension Associated with
Insight into Pulmonary Arterial Hypertension Associated with

... Currently, the AT can improve exercise capacity, hemodynamic parameters, functional class, quality of life and survival in adults with PAH, especially IPAH, connective tissue disease (CTD-APAH) or anorexigen-APAH. Therein, some patients with IPAH had been treated successfully with vasodilators with ...
Cardiac, skeletal, and smooth muscle mitochondrial - AJP
Cardiac, skeletal, and smooth muscle mitochondrial - AJP

... the arterial system, dictates the distribution of blood flow and O2 transport, dependent on need (6, 33). Each of these distinct muscle tissues contain mitochondria, which consume O2 and produce ATP through cellular respiration. Interestingly, although mitochondrial respiration of both cardiac and s ...
Case-Based Curriculum in Clinical Electrophysiology
Case-Based Curriculum in Clinical Electrophysiology

... the change in ventricular activation extends beyond the immediate mechanical effects as reviewed by Cho and colleagues.29 Autopsy analysis of the implantation site of a permanent selective direct his bundle pacing lead. Correa de Sa DD, et al.30 ...
Cardiac, skeletal, and smooth muscle
Cardiac, skeletal, and smooth muscle

... the arterial system, dictates the distribution of blood flow and O2 transport, dependent on need (6, 33). Each of these distinct muscle tissues contain mitochondria, which consume O2 and produce ATP through cellular respiration. Interestingly, although mitochondrial respiration of both cardiac and s ...
Echocardiography Cardio
Echocardiography Cardio

... flow signal is limited since the signal can originate at any point along the length or width of the ultrasound beam ...
Cardiac magnetic resonance imaging in congenital heart disease
Cardiac magnetic resonance imaging in congenital heart disease

... ing a high temporal resolution requires decreasing the ...
The multi-modality cardiac imaging approach to the Athlete`s heart
The multi-modality cardiac imaging approach to the Athlete`s heart

... imposed on the heart during exercise (Figure 1). Endurance training would lead, as a consequence of volume overload and increased diastolic wall stress, to eccentric LVH (LV mass increase with increased LV cavity dimension). In contrast, strength training leads, as a consequence of pressure overload ...
Paper - Journal of American Science
Paper - Journal of American Science

... system with melatonin treatment as one of the suggested triggers of preconditioning. Thirty male Albino rats were divided into three equal groups, sham- operated control rats, 5/6 subtotal nephrectomized (STNx) group and 5/6 subtotal nephrectomized melatonin- supplemented (STNx + M) group. Melatonin ...
Resistance With Elevated Pulmonary Vascular Evaluation of
Resistance With Elevated Pulmonary Vascular Evaluation of

... each followed by hemodynamic measurements and sampling for arterial and mixed venous oxygen content. The experimental period of spontaneous breathing procedure started with a control at an inspiratory fraction of oxygen of 30% via a tightfitting face mask in a nonrebreathing system. After baseline h ...
Third universal definition of myocardial infarction
Third universal definition of myocardial infarction

... of MI and must be determined for each specific assay with appropriate quality control in each laboratory.8,9 The values for the 99th percentile URL defined by manufac­ turers, including those for many of the high-sensitivity assays in development, can be found in the package inserts for the assays o ...
Clinical recommendations for cardiopulmonary exercise testing data
Clinical recommendations for cardiopulmonary exercise testing data

... as haemodynamics and heart rate (HR), will either be reported alongside ventilatory expired gas analysis data or reported separately. In either situation, the majority of essential data is readily obtained. O2 pulse and (change in VO2 /change in Watt (DVO2 /DW) plots are often generated by customary ...
Recent findings on the health effects of omega-3 statins inhibit omega-3?
Recent findings on the health effects of omega-3 statins inhibit omega-3?

... Thus, in the first category, we have retained three RCTs. The first one was published in June 2005 and reported no significant effect of 1.3 g/day of EPA+DHA [18]. The omega-3 index of patients receiving EPA+DHA increased from 4.7 to 8.3% indicating that patients were not n-3 deficient at baseline a ...
Oxygen therapy for acute myocardial infarction
Oxygen therapy for acute myocardial infarction

... breathe. We looked for the evidence to support this practice by searching for randomised controlled trials that compared the outcomes in patients given oxygen to the outcomes for patients given normal air to breathe. We were primarily interested in seeing whether there was a difference in the number ...
Multimodality Imaging Strategies for the Assessment of Aortic Stenosis
Multimodality Imaging Strategies for the Assessment of Aortic Stenosis

... From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovasc ...
Doppler echocardiographic evaluation of right and left
Doppler echocardiographic evaluation of right and left

... The importance of ventricular systolic abnormalities in the development of congestive heart failure has long been recognized. Only recently have abnormalities of diastolic function been appreciated (1). Diastolic dysfunction has been described (2-6) in pediatric and adult patients with left ventricu ...
Several of the cells have drop down menus with them – if you see an
Several of the cells have drop down menus with them – if you see an

... Pre BiV transplant status (Not listed, 1a,1b,2,7): Listed or not and status in 24 hours prior to BiV placement Duration of Data Collection Period Pre BiV: We would like to review clinical events for a maximum of 1 year prior to biV. In some cases, due to patient age, referral date or onset of diseas ...
Running head: ATRIAL FIBRILLATION
Running head: ATRIAL FIBRILLATION

... Treatment Much research has been done on the treatment of atrial fibrillation. Many different options are available and are chosen based on a variety of details. The patients symptoms, the type of atrial fibrillation as well as the risk factors of the patient are all considered when determining the ...
< 1 ... 54 55 56 57 58 59 60 61 62 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report