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Patients With Coronary Artery Disease Unsuitable
Patients With Coronary Artery Disease Unsuitable

... does not pose immediate threat to life. Consequently, angina cannot be used alone to justify testing potentially hazardous therapies in clinical trials. Investigational therapies should not be offered if the anticipated hazards exceed the natural mortality and morbidity rates expected for study part ...
time course of isovolumetric relaxation
time course of isovolumetric relaxation

... heart was paced at a constant rate of 120 beats/min. A micromanometer (Millar Mikrotip) was calibrated to mercury at 370 C and introduced into the left ventricle from the right carotid artery. In two dogs endocardial sonomicrometer crystals were positioned in the minor (anteroposterior) axis to meas ...
Running head: ATRIAL FIBRILLATION
Running head: ATRIAL FIBRILLATION

... Treatment Much research has been done on the treatment of atrial fibrillation. Many different options are available and are chosen based on a variety of details. The patients symptoms, the type of atrial fibrillation as well as the risk factors of the patient are all considered when determining the ...
Cardiac Pacing - Patient Management
Cardiac Pacing - Patient Management

... The nursing management for patients with artificial pacemakers including removal of pacing wires is discussed. ...
Evidence of Incomplete Left Ventricular Relaxation in the Dog
Evidence of Incomplete Left Ventricular Relaxation in the Dog

... beat began before 3.5 T but did not always occur under these conditions. Thus, an increase in end diastolic pressure relative to diastolic volume may result from incomplete relaxation under conditions of sufficiently rapid heart rate or sufficiently prolonged ventricular relaxation. Incomplete relax ...
catheter ablation reimbursement guide
catheter ablation reimbursement guide

... procedures regarding the appropriate medical strategies to minimize risk when using contrast media. The CryoAblation (Arctic Front Advance and Freezor MAX) family of catheters were not studied for safety of changes in anticoagulation therapy in patients with atrial fibrillation. This equipment shoul ...
Role of Cardiac Myocyte CXCR4 Expression in Development and
Role of Cardiac Myocyte CXCR4 Expression in Development and

... immediate and transient and cardiac myocyte CXCR4 expression is delayed and persistent following AMI.12,13 More recently, the hypothesis has been forwarded that the basis of benefit associated with stem cell therapy following acute myocardial infarction is the restoration of the temporal alignment o ...
Assessment of Diastolic Hemodynamics by Analyzing Left
Assessment of Diastolic Hemodynamics by Analyzing Left

... diastolic hemodynamics and cardiac alterations or geometric remodeling in patients with hypertension. In the present study, we used LVDd, LVMI, and RWT as the parameters of cardiac alterations and geometric remodeling, and we assessed the relation between ventricular LV filling flow propagation and ...
Full-Text PDF
Full-Text PDF

... divergence of contractile proteins [1]. There are no chambers or valves discernible and the tube itself does not show morphological polarity [11]. The heart tube is situated on the ventral side of the body, close to the stomach. It opens into single vessels at the posterior end connecting to the end ...
syncope
syncope

... TIME (Months) ...
life with inherited abnormal heart rhythms
life with inherited abnormal heart rhythms

... medicines may provide new treatment options. These medicines block the disturbances in your heart rhythm that can cause sudden death. However, the long-term benefits of these treatments are unknown. Potassium supplements may also be prescribed by your doctor and have been successful in some cases. ...
Bradycardia in Children During General Anaesthesia
Bradycardia in Children During General Anaesthesia

... outcome was reported in 63% of both adults and children, in only 48% of incidents concerning children a good outcome was reported. This might indicate that an incident during general anaesthesia with bradycardia in children has an important risk of poor outcome. An epidemiologic study by Keenan and ...
Extrinsic Compression of the Left Coronary Ostium by the Pulmonary
Extrinsic Compression of the Left Coronary Ostium by the Pulmonary

... directional compression by the dilated pulmonary artery. Right coronary injection showed septal branches of the left anterior descending coronary artery filling through collateral vessels; these were also free of irregularities. Stenting of the LMCA ostium was done with the intention to provide a m ...
Anomalous left coronary artery from the pulmonary artery (ALCAPA
Anomalous left coronary artery from the pulmonary artery (ALCAPA

... 10). In one case, it was possible to selectively cannulate the left coronary artery through the pulmonary artery The surgical technique was chosen based on anatomical findings. On three patients, coronary reimplantation was performed. Takeuchi procedure was performed in one patient and in other an i ...
ECG Recording - Learning Central
ECG Recording - Learning Central

... • External pacing function for bradyarrythmias The ECG display screen allows for ECG monitoring, using either leads or pads applied to the anterior chest. The difference between ‘defibrillation’ and ‘cardioversion’ is dependant on the type of the dysrhythmia and the level of compromise to the patien ...
Review article NATRIURETIC PEPTIDES IN CARDIOVASCULAR
Review article NATRIURETIC PEPTIDES IN CARDIOVASCULAR

... constitutive pathway from the ventricles. ANP is immediately released from atrial cell granules, which, coupled with its very short half-life, results in dynamic changes in its concentration in the blood. The secretion of BNP is mainly from the left ventricular cardiomyocytes, is controlled at the t ...
ASNC Review of the ACCF/ASNC Appropriateness Criteria for
ASNC Review of the ACCF/ASNC Appropriateness Criteria for

... SPECT MPI testing. These new indications and data to support them are as follows: Syncope. In the evaluation of unexplained syncope, the recently published AHA/ACCF Scientific Statement on the Evaluation of Syncope considers an ischemia evaluation “appropriate in patients at risk for or with a histo ...
What`s new in diagnosis and therapy of atrial fibrillation?
What`s new in diagnosis and therapy of atrial fibrillation?

... of 2.5% is relatively low, PV isolation is nowadays the first choice therapy for symptomatic patients with drug-resistant paroxysmal AF. To reduce the most frequent reason for AF recurrence after PV isolation, i.e. reconnection of formerly isolated PV, new techniques including pharmacological testin ...
Lymphatics of the Heart
Lymphatics of the Heart

... AV valve annuli have not been identified but there is some evidence that they exist and they are seen easily in dogs and pigs. There has been some question about the presence of lymphatics in valves, especially the mitral, since it is so often the seat of disease.3 Wearn et al.19 were of the opinion ...
A caudorostral wave of RALDH2 conveys anteroposterior
A caudorostral wave of RALDH2 conveys anteroposterior

... Shortly after that, cells in the lateral mesoderm differentiate into endocardial and myocardial types that will organize the primitive circulatory pump: the heart tube. It is only after the basic circulatory plan is laid down, with separate conduits to and from tissues, that pumping from the heart i ...
Atrial Fibrillation in the Setting of Acute Myocardial Infarction
Atrial Fibrillation in the Setting of Acute Myocardial Infarction

... stroke, active bleeding and recent trauma or major surgical intervention. Data from 40,891 patients (99.7%) were complete for analysis; other patients (n 5 130) were excluded. We reviewed case report form and baseline ECG data on all patients to obtain information about atrial fibrillation. Patients ...
I IIa IIb III - Professional Heart Daily
I IIa IIb III - Professional Heart Daily

... • Patients presenting with angina should be categorized as stable vs. unstable. Those at moderate or high risk should be treated emergently for acute coronary syndrome. • A standard exercise test is the first choice to diagnose IHD for patients with an interpretable ECG and able to exercise, especia ...
Caffeine and Ventricular Arrhythmias
Caffeine and Ventricular Arrhythmias

... in six (27%), and decreased in six (27%). Rhythm severity was unchanged in 17 patients (77%), more severe in two (9%), and less severe in three (14%). In those patients with clinical ventricular arrhythmias, caffeine did not significantly alter inducibility or severity of arrhythmias, suggesting lit ...
Echocardiographic Evaluation of Pericardial Disease
Echocardiographic Evaluation of Pericardial Disease

... possibly the appearance of a dilated right ventricle when assessed through the transthoracic parasternal window. A small series of patients (n=8) from a Japanese group reported more marked alterations in venous return in the right heart (measured in the superior vena cava) than in the left heart (me ...
Left ventricular hypertrophy in athletes
Left ventricular hypertrophy in athletes

... Athletic training is associated with statistically significant increases in cardiac dimensions compared with sedentary individuals. A meta-analysis of almost 1000 M-mode echocardiographic studies in highly trained male athletes showed that athletes exhibited a 15–20% increase in septal and left vent ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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