• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Alternate Pacing Sites in the Atria and the Right Ventricle
Alternate Pacing Sites in the Atria and the Right Ventricle

... while the remainder fell back into chronic atrial fibrillation.18 Biatrial pacing after the internal electrical cardioversion of atrial fibrillation appears to have a beneficial effect, according to one study with a rather small number of patients. After 3 months follow up 8 out of 11 patients remai ...
Congestive Heart Failure Educational Handbook
Congestive Heart Failure Educational Handbook

... Heart failure is a common problem among older adults in the United States. This year, approximately 550,000 Americans will learn from their doctors that they have heart failure. That is in addition to the nearly 5 million people who already have the condition. Many people with heart failure do not k ...
Applied Anatomy of the Heart and Great Vessels
Applied Anatomy of the Heart and Great Vessels

... Focal adhesions are usually unimportant, but occasionally they may allow the accumulation of loculated fluid or, rarely, tamponade of an individual cardiac chamber, usually the right ventricle. After cardiac surgery, the opened pericardial cavity may become sealed again if the parietal pericardium a ...
Articles in PresS. Am J Physiol Heart Circ Physiol (November 20
Articles in PresS. Am J Physiol Heart Circ Physiol (November 20

... Department of Cardiology, Xijing hospital, Fourth military medical university 169 West Changle Road, Xi’an, Shannxi 710032, China. E-mail: [email protected] and [email protected] ...
Surgical Treatment of Atrial Fibrillation Through Isolation of the Left
Surgical Treatment of Atrial Fibrillation Through Isolation of the Left

... this context, atrial fibrillation of a rheumatic nature continues to be an extremely important clinical problem. In patients with mitral valve disease and atrial fibrillation, surgical correction of valvular dysfunction does not usually result in a solution for arrhythmia, because the indices of rec ...
Management of stable angina. - Scottish Intercollegiate Guidelines
Management of stable angina. - Scottish Intercollegiate Guidelines

... proportion of the population who have consulted their general practice because of a definite diagnosis of angina based on ISD’s standard morbidity grouping). In the year ending March 2005 the annual prevalence rate is given as 8.3 for men and 7.6 for women per 1,000 population. This equates to an es ...
34066-Review - F6 Publishing Home
34066-Review - F6 Publishing Home

... Both the current American and European guidelines recommend correction of relevant functional tricuspid insufficiency if other cardiac diseases are corrected surgically[4,7] since functional tricuspid regurgitation, a frequent finding in patients undergoing cardiac surgery for other reasons[5], has ...
Falls-associated elevation of troponin level in an older woman with
Falls-associated elevation of troponin level in an older woman with

... In March 2015, a 75-year old woman was taken by ambulance to the emergency department with a head injury and scalp laceration secondary to a nonsyncopal fall. She had normal cognitive function and no history of ischaemic heart disease, diabetes mellitus, or hypertension. She was a non-smoker and non ...
Chest Compressions Cause Recurrence of Ventricular Fibrillation
Chest Compressions Cause Recurrence of Ventricular Fibrillation

... immediately after defibrillation. We hypothesized that immediate CPR resumption promotes earlier recurrence of ventricular fibrillation (VF). Methods and Results—This study used data of a prospective per-patient randomized controlled trial. Automated external defibrillators used by first responders ...
infective endocarditis at bicuspid aortic valve complicated with
infective endocarditis at bicuspid aortic valve complicated with

... to control progressive heart failure. On the other hand, if valve replacement is selected first, cardiopulmonary bypass with systemic heparinization could cause lethal neurologic deficits.18 Some patients with infective endocarditis require both cardiac valve replacement and intracranial infective a ...
Here - The Egyptian Cardiac Rhythm Association
Here - The Egyptian Cardiac Rhythm Association

... electrophysiologic study. Recurrent ventricular tachycardia was defined as well tolerated to allow adequate mapping when systolic pressure was ⬎70 mm Hg with no signs of low cerebral flow or cardiac output. These patients were selected to undergo radiofrequency energy (RF) ablation. The VT was inces ...
Non-invasive detection of conduction pathways
Non-invasive detection of conduction pathways

... using atrial wave template and maximum cross correlation.27 Atrial ectopic beats and excessively noisy sinus beats were rejected. If two distinct sinus P-wave morphologies were present, both were separately averaged. The onset and end of the P-wave as well as P-wave duration were automatically deter ...
Anomalous origin of left main coronary artery from the right sinus of
Anomalous origin of left main coronary artery from the right sinus of

... the wrong sinus of Valsalva are the second most common cause of death on an athletic field [11,16–21]. Sudden death during or immediately after athletic or vigorous physical activity can occur at any age, but since most competitive athletes are under age 50, sudden death secondary to a cardiac anoma ...
Sympathetic Innervation Alters Growth and Intrinsic Heart Rate of
Sympathetic Innervation Alters Growth and Intrinsic Heart Rate of

... the embryonic chick heart by injection of either reserpine or 6-hydroxydopamine in ovo altered neither the subsequent growth of the heart in ovo nor the developmental changes in its inotropic sensitivity to /3-adrenergic receptor stimulation.15 Postnatal sympathectomy of rats with either 6-hydroxydo ...
New methods of studying affections of the heart.
New methods of studying affections of the heart.

... Kent, His, jun., and others. This muscle tissue is distinct in its functions from the more striated muscle fibres in that the wave of conductivity passes more slowly over its fibres, and it possesses a greater power of automatically creating a stimulus for contraction. In the human subject these pec ...
CARDIAC IMAGING GUIDELINES
CARDIAC IMAGING GUIDELINES

... obstructive disease.  Need to evaluate exercise-induced valve dysfunction such as mitral regurgitation due to papillary muscle ischemia  If the exercise treadmill stress test is equivocal, inconclusive, or inadequate (e.g. double product < 25,000)  Stress testing with imaging can be performed wit ...
Cardiac malpositions and syndromes with right or left atrial isomerism
Cardiac malpositions and syndromes with right or left atrial isomerism

... that a high risk for situs inversus was in a family with a previous child with this condition, in consanguineous couples, and in the offspring of diabetic mothers. However, there are other conditions where the mirror-image arrangement is partial: either only affecting the heart, as in dextrocardia ( ...
Guidelines on the management of stable angina pectoris
Guidelines on the management of stable angina pectoris

... evidences on a particular subject in order to help physicians to select the best possible management strategies for the individual patient, suffering from a specific condition, not only taking into account the impact on outcome, but also the risk–benefit ratio of a particular diagnostic or therapeutic ...
The heart requires glycerol as an energy substrate through
The heart requires glycerol as an energy substrate through

... and substrates that may serve as possible candidates for a cardiac energy source have not been fully studied. Several reports showed that a moderate expression of aquaporin 7 (AQP7), a member of the aquaglyceroporin family that is permeated by glycerol and water, is observed in heart tissue. However ...
CARDIAC AND CORONARY ARTERY ANATOMY
CARDIAC AND CORONARY ARTERY ANATOMY

Compound heterozygous or homozygous truncating
Compound heterozygous or homozygous truncating

... sarcomeric or sarcomere-associated cardiac muscle proteins. The disease mainly affects adults, although young children with severe HCM have also been reported. We describe four unrelated neonates with lethal cardiomyopathy, and performed molecular studies to identify the genetic defect. We also pres ...
Rectilinear Biphasic Defibrillation
Rectilinear Biphasic Defibrillation

... 14 M Series Operator’s Guide, Rectilinear Biphasic Waveform Defibrillator Option Insert, 9650-0209-01:4-5. For defibrillation of VF. “... data also demonstrate the superior efficacy of low-energy rectilinear biphasic shocks in patients with high transthoracic impedance at 90%** confidence level. **K ...
Doppler Echocardiography and Hemodynamic Parameters in
Doppler Echocardiography and Hemodynamic Parameters in

... cut-off values with sensitivity around or above 0.80. In all procedures, we adopted the value 0.05 as significance level. ...
For peer review only
For peer review only

... or review board approval was obtained in each of the seven participating countries, and all patients provided informed consent. Each patient was given a unique identification number to prevent double counting. The study is registered at clinicaltrials.gov with number NCT01467973. ...
ischemi̇c heart 2013
ischemi̇c heart 2013

... In some of the cases, the coronary arteries are free of atherosclerosis by angiography:  Vasospasm with or without coronary atherosclerosis may induce the acute perfusion deficit, perhaps in association with platelet aggregation.  Emboli from a left-sided mural thrombosis or vegetative endocarditi ...
< 1 ... 53 54 55 56 57 58 59 60 61 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report