CHAPTER TWO: LITERATURE REVIEW PATHOGENESIS AND ETIOLOGY 2.2 CLINICAL FEATURES
... population. All races are affected, although some, like the Chinese to a lesser extent (0.3%) and others like the Pima Indians (5%), more so. A prevalence of 0.9% has been reported in an urban black South African (SA) population. However, some rural areas in SA reported hardly any cases(8,9). Female ...
... population. All races are affected, although some, like the Chinese to a lesser extent (0.3%) and others like the Pima Indians (5%), more so. A prevalence of 0.9% has been reported in an urban black South African (SA) population. However, some rural areas in SA reported hardly any cases(8,9). Female ...
Heart Online First, published on December 30, 2005 as 10.1136/hrt.2005.077164
... No-reflow has been associated with severe myocardial injury, progressive left ventricular remodeling, congestive heart failure, and poor prognosis [4-6]. Therefore, myocardial tissue perfusion is now accepted as a target of reperfusion therapy for AMI [7]. Specific platelet glycoprotein IIb/IIIa rec ...
... No-reflow has been associated with severe myocardial injury, progressive left ventricular remodeling, congestive heart failure, and poor prognosis [4-6]. Therefore, myocardial tissue perfusion is now accepted as a target of reperfusion therapy for AMI [7]. Specific platelet glycoprotein IIb/IIIa rec ...
carl john wiggers - National Academy of Sciences
... about the latter, he devoted one morning each week to attending ward rounds in Bellevue Hospital. He kept improving the reflecting mirror manometer of Otto Frank and devised a mobile unit that brought his equipment into use at the bedside. He was promoted to Assistant Professor of Physiology in 1913 ...
... about the latter, he devoted one morning each week to attending ward rounds in Bellevue Hospital. He kept improving the reflecting mirror manometer of Otto Frank and devised a mobile unit that brought his equipment into use at the bedside. He was promoted to Assistant Professor of Physiology in 1913 ...
Aberrant Intracellular Calcium Cycling in the Heart
... Heart disease is the biggest killer world-wide, causing a quarter of all deaths. During the past two decades, it has also risen above infectious diseases as the leading cause of years of life lost. Heart failure, characterized by weak pump function of the heart, and disturbances in heart rhythm (arr ...
... Heart disease is the biggest killer world-wide, causing a quarter of all deaths. During the past two decades, it has also risen above infectious diseases as the leading cause of years of life lost. Heart failure, characterized by weak pump function of the heart, and disturbances in heart rhythm (arr ...
Pacemaker Therapy - Boston Scientific
... How big is a pacemaker and where is it implanted?....................................................... 10 Are there risks to the procedure?.................................................................................... 11 What is recovery like?................................................. ...
... How big is a pacemaker and where is it implanted?....................................................... 10 Are there risks to the procedure?.................................................................................... 11 What is recovery like?................................................. ...
Syncopal Attacks Imitating Epileptic Seizures
... Cardiogenic syncopes are potentially life threatening and may be treatable. Morbidity and mortality is up to 50% within the first 3 years following the initial attack, and it is cause-dependent. Palpitations, chest pain, shortness of breath, extreme fatigue or other features of cardiovascular insuffic ...
... Cardiogenic syncopes are potentially life threatening and may be treatable. Morbidity and mortality is up to 50% within the first 3 years following the initial attack, and it is cause-dependent. Palpitations, chest pain, shortness of breath, extreme fatigue or other features of cardiovascular insuffic ...
Apical Right Ventricular Hypertrophic Cardiomyopathy—A Case
... 47% of cases. This case was asymptomatic with no family history, no physical findings and had a normal ECG. Echocardiography has been universally accepted as the initial imaging modality in investigation of patients with apical HCM. Wall thickness of the right ventricle can be measured by two-dimens ...
... 47% of cases. This case was asymptomatic with no family history, no physical findings and had a normal ECG. Echocardiography has been universally accepted as the initial imaging modality in investigation of patients with apical HCM. Wall thickness of the right ventricle can be measured by two-dimens ...
lxxi. the isolation of histamine from
... the silver fractionations being rather larger than usual (41 % instead of about 25 %). The yield from the picrate stage is certainly low, but it must be remembered that the experiment was performed on a very small scale. Consequently, since sufficient volume of liquid had to be left for manipulation ...
... the silver fractionations being rather larger than usual (41 % instead of about 25 %). The yield from the picrate stage is certainly low, but it must be remembered that the experiment was performed on a very small scale. Consequently, since sufficient volume of liquid had to be left for manipulation ...
Systolic and Diastolic Abnormalities Reduce the Cardiac Response
... presumably by a reduction in stroke volume (9–11). Lalande et al. (6) found that a small group of men with T2DM had shorter diastolic duration and an increased reliance on late diastolic filling that accompanied smaller end-diastolic and stroke volumes. However, resting measurements may be misleading ...
... presumably by a reduction in stroke volume (9–11). Lalande et al. (6) found that a small group of men with T2DM had shorter diastolic duration and an increased reliance on late diastolic filling that accompanied smaller end-diastolic and stroke volumes. However, resting measurements may be misleading ...
Invasive Hemodynamic Monitoring
... The cardiac cycle consists of nearly synchronized activity of the atria and ventricles. The sequence is essentially the same for the right and left sides of the heart. For general discussion, systole and diastole are the two basic phases. However, when examining the cycles closer there are many diff ...
... The cardiac cycle consists of nearly synchronized activity of the atria and ventricles. The sequence is essentially the same for the right and left sides of the heart. For general discussion, systole and diastole are the two basic phases. However, when examining the cycles closer there are many diff ...
Preview the material
... Although it is not necessary to have a deep understanding of cardiac electrophysiology to diagnose and treat a cardiac arrhythmia, some knowledge of the basics is helpful. Tachycardias are mostly caused by re-entry or abnormal automaticity. A few rare types of tachycardia are probably caused by a th ...
... Although it is not necessary to have a deep understanding of cardiac electrophysiology to diagnose and treat a cardiac arrhythmia, some knowledge of the basics is helpful. Tachycardias are mostly caused by re-entry or abnormal automaticity. A few rare types of tachycardia are probably caused by a th ...
Using Vectorcardiography In Cardiac Resynchronization Therapy
... A more objective and reproducible method is to measure the amount of pressure increase per unit of time (or dP/dt) in the left ventricle, which evaluates the pumping effectiveness of the heart. An optimal lead placement and an optimal timing interval between the pacing electrodes for the biventricul ...
... A more objective and reproducible method is to measure the amount of pressure increase per unit of time (or dP/dt) in the left ventricle, which evaluates the pumping effectiveness of the heart. An optimal lead placement and an optimal timing interval between the pacing electrodes for the biventricul ...
An introduction to electrocardiogram monitoring
... provides a continuous display of the patient’s ECG. Common features of a cardiac monitor include: • screen: a dull/bright switch can be adjusted if the screen is too light or too dark; • ECG printout facility: to record cardiac arrhythmias (helpful for both diagnosis and record keeping). On most Cri ...
... provides a continuous display of the patient’s ECG. Common features of a cardiac monitor include: • screen: a dull/bright switch can be adjusted if the screen is too light or too dark; • ECG printout facility: to record cardiac arrhythmias (helpful for both diagnosis and record keeping). On most Cri ...
percutaneous coronary intervention in patients with atrial
... risk of major bleeding (I). Uninterrupted warfarin treatment did not increase perioperative complications and seemed to decrease bleeding complications compared to heparin bridging (II). Already mild renal impairment (eGFR 60– 90mL/min) was associated with a 2.3‐fol ...
... risk of major bleeding (I). Uninterrupted warfarin treatment did not increase perioperative complications and seemed to decrease bleeding complications compared to heparin bridging (II). Already mild renal impairment (eGFR 60– 90mL/min) was associated with a 2.3‐fol ...
Anita Sharma Timilsina EFFECT OF EXERCISE INTENSITY AND
... I thank my family. I wish to thank my husband Kamal and my son Nirvan, for always being there for me. This would have not been possible without you. Trondheim May 2014 ...
... I thank my family. I wish to thank my husband Kamal and my son Nirvan, for always being there for me. This would have not been possible without you. Trondheim May 2014 ...
2000 The European Society of Cardiology
... the following reviewers: J. Adgey (U.K.), J. P. Bassand ...
... the following reviewers: J. Adgey (U.K.), J. P. Bassand ...
Comprehensive assessment of biventricular function and aortic
... Introduction The haemodynamic load caused by long-term training involves both cardiac ventricular chambers, inducing an increase in ventricular diameters, wall thickness, and mass. These changes are usually described as ‘athlete’s heart’.1 – 3 Adaptations to exercise are dependent on the specific ty ...
... Introduction The haemodynamic load caused by long-term training involves both cardiac ventricular chambers, inducing an increase in ventricular diameters, wall thickness, and mass. These changes are usually described as ‘athlete’s heart’.1 – 3 Adaptations to exercise are dependent on the specific ty ...
Myocardial structure, function and ischaemic tolerance in a rodent
... p<0.01) as compared to control hearts. These changes were associated with reductions in RISK pathway function with 30-50%, and 40-60% reductions in Akt and GSK-3β expression and phosphorylation respectively in obese rat hearts compared to controls. Total eNOS expression was reduced by 25% in obese r ...
... p<0.01) as compared to control hearts. These changes were associated with reductions in RISK pathway function with 30-50%, and 40-60% reductions in Akt and GSK-3β expression and phosphorylation respectively in obese rat hearts compared to controls. Total eNOS expression was reduced by 25% in obese r ...
Evidence-Based Guidelines for Cardiovascular Disease Prevention
... findings with observational studies of hormone therapy (10). Some commonly used preventive interventions lacked clinical trial data for women, and it was unclear whether results of studies conducted in men could be generalized to women. Since the 2003 literature review, numerous clinical trials that ...
... findings with observational studies of hormone therapy (10). Some commonly used preventive interventions lacked clinical trial data for women, and it was unclear whether results of studies conducted in men could be generalized to women. Since the 2003 literature review, numerous clinical trials that ...
Chapter 6
... mitral valve. The atrial margin of the AVN is apposed to the myocardialized vestibular spine, containing the tendon of Todaro, while the ventricular margin of the AVN is continuous with the bundle of His. The slow pathway of the AVN (green) is a myocardial inferior extension of the compact part of t ...
... mitral valve. The atrial margin of the AVN is apposed to the myocardialized vestibular spine, containing the tendon of Todaro, while the ventricular margin of the AVN is continuous with the bundle of His. The slow pathway of the AVN (green) is a myocardial inferior extension of the compact part of t ...
Full Text - Circulation
... produced guidelines in the area of cardiovascular disease since 1980. The ACCF/AHA Task Force on Practice Guidelines (Task Force), charged with developing, updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are ...
... produced guidelines in the area of cardiovascular disease since 1980. The ACCF/AHA Task Force on Practice Guidelines (Task Force), charged with developing, updating, and revising practice guidelines for cardiovascular diseases and procedures, directs and oversees this effort. Writing committees are ...
The Effects of /3-Adrenergic Stimulation on the
... Patients were eligible for this prospective study if they had (1) clinical sustained VT, ventricular fibrillation, aborted sudden cardiac death, or syncope resulting from VT, (2) inducible sustained VT during baseline drug-free electrophysiologic study, and (3) they were treated for clinical indicat ...
... Patients were eligible for this prospective study if they had (1) clinical sustained VT, ventricular fibrillation, aborted sudden cardiac death, or syncope resulting from VT, (2) inducible sustained VT during baseline drug-free electrophysiologic study, and (3) they were treated for clinical indicat ...
Comparative Ultrastructural Morphometry Of The Relationship
... T-tubules as invaginations of the sarcolemma increase surface area of cell membrane available in myocyte for metabolic exchanges. In animals in which they feature prominently, metabolic exchanges in myocardial cells would be more efficient. This would protect cardiac cells with such features from ar ...
... T-tubules as invaginations of the sarcolemma increase surface area of cell membrane available in myocyte for metabolic exchanges. In animals in which they feature prominently, metabolic exchanges in myocardial cells would be more efficient. This would protect cardiac cells with such features from ar ...
Exercise Recommendations for Persons with Special Needs
... Exercise-related Sudden Death in Patient with Cardiac Diseases • CHD accounts for most exercise-related sudden deaths among those aged 35 years or above • A considerable number of fatal MIs were not due to significant stenosis of the coronary arteries but rupture of unstable coronary atheroscleroti ...
... Exercise-related Sudden Death in Patient with Cardiac Diseases • CHD accounts for most exercise-related sudden deaths among those aged 35 years or above • A considerable number of fatal MIs were not due to significant stenosis of the coronary arteries but rupture of unstable coronary atheroscleroti ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.