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Biochemical markers
Biochemical markers

... Simplest and least expensive form Sensitivity are low as 70% Normal test has a strong negative predictive value ...
Dysrhythmia (BASIC) Exam Content Outline
Dysrhythmia (BASIC) Exam Content Outline

... Dysrhythmia (BASIC) Exam Content Outline Exam Objective: To measure the overall level of clinical knowledge in the area of Basic Rhythm Interpretation. ...
DOCX ENG
DOCX ENG

... acute myocardial infarction, and CHF according to the current guidelines. For primary prevention of AF, post hoc analyses of randomized trials and observations from nonrandomized studies have suggested that ACEI and ARBs reduce the incidence of new-onset AF. In patients with end-stage renal disease ...
souviner - WCC & IVUS 2015
souviner - WCC & IVUS 2015

... of developing heart disease. Pregnancy related heart diseases require special attention. Older women also require attention as it's never too late to take action to prevent and control the risk factors for heart disease, especially degenerative aortic valve diseases. Even those who have heart diseas ...
Heart Rhythm Refresher Course 2014 Module 1: My Diagnostic
Heart Rhythm Refresher Course 2014 Module 1: My Diagnostic

... history of MI, CV risk profile, triggering factors (exercise, stress – eg. ACS, WPW, HCM, AS, CPVT ) 2. Family history of hereditary cardiac arrhythmia or congenital heart disease, FH of SCD 3. Transient and reversible causes 4. Evaluation for structural heart disease 5. Evaluation for those without ...
Medical Treatment - American Heart Association
Medical Treatment - American Heart Association

... Digoxin may also be used to prevent certain kinds of tachycardias. Bradycardia may be associated with certain congenital heart defects or may develop by itself before birth or after heart surgery. In some more serious cases and/or if the heart rate is very slow, an artificial pacemaker may be needed ...
Slide Set - American College of Cardiology
Slide Set - American College of Cardiology

... ACC indicates American College of Cardiology; AHA, American Heart Association; ADHF, acute decompensated heart failure; BNP, B-type natriuretic peptide; COR, Class of Recommendation; ED, emergency department; HF, heart failure; NT-proBNP, Nterminal pro-B-type natriuretic peptide; NYHA, New York Hear ...
Implantable Cardioverter Defibrillator (ICD)
Implantable Cardioverter Defibrillator (ICD)

... sophisticated algorithm to detect and treat episodes of VT, VF, and additionally atrial fibrillation (AF). The prevention and treatment of atrial fibrillation (AF) focuses first on maintaining or restoring sinus rhythm (SR), and then on controlling rate and preventing thromboembolic events. ICDs may ...
Role of Cardiac Rehabilitation in Secondary Prevention
Role of Cardiac Rehabilitation in Secondary Prevention

... • Heart transplant and valve replacements patients benefit from cardiac rehabilitation • CHF patients also likely benefit, but not a Medicare covered service for CHF in US – HF ACTION will likely have negative effects on getting CHF approved for cardiac rehab ...
Appearance of QRS fragmentation late after Mustard/ Senning repair
Appearance of QRS fragmentation late after Mustard/ Senning repair

... Units are listed in number (%) unless otherwise indicated. HTx, heart transplantation; ICD, implantable cardioverter defibrillator; PM, pacemaker; RV, right ventricular; SAVV, systemic atrioventricular valve. ...
Hypertensive Heart Failure in Nigerian Africans: Insights from the
Hypertensive Heart Failure in Nigerian Africans: Insights from the

... were consecutively studied, comprising 184 men (57.5%) and 136 women (42.5%) aged 58.412.4 and 60.6 14.5 years, respectively. Most patients (80%) presented with New York Heart Association functional class III or IV and around one third (35%) had preserved systolic function. Median hospital stay wa ...
Comparison of Effects on Left Ventricular Filling Pressure of
Comparison of Effects on Left Ventricular Filling Pressure of

... decrease in PCWP compared with baseline; this trend persisted through the 3-hour time period (Figure 1 and FIGURE 2. Change in PCWP from baseline during 24 hours of Table 3). In contrast, intravenous nitroglycerin was intravenous infusion of nitroglycerin and nesiritide. Squares, nesiritide; diamond ...
Artificial Heart - Sponsors Choose
Artificial Heart - Sponsors Choose

Editorial to PBMB_2016_7_Hondeghem-Final
Editorial to PBMB_2016_7_Hondeghem-Final

... To date no single electrical surrogate parameter in patients, and no single cellular, tissue or whole animal model, including computer simulations, enables reliable clinical risk prediction [Haverkamp et al. 2000; Mirams et al. 2012]. Therefore, potential new drugs are evaluated by a combined integr ...
NT- pro-BNP - journal of evolution of medical and dental sciences
NT- pro-BNP - journal of evolution of medical and dental sciences

... synthesized largely by the heart in the form of pre-pro-BNP which is cleaved to pro-BNP, and then proteolyzed to BNP and NT-pro-BNP. ANP, BNP and NT-pro-BNP are sensitive diagnostic markers for heart failure. NT-pro-BNP being more sensitive is preferable to BNP and ANP for the detection of heart fai ...
Improvement in MR and in the dyssynchrony between the mid
Improvement in MR and in the dyssynchrony between the mid

... Cardiac resynchronization therapy (CRT) has been shown to improve symptoms, increase exercise capacity, decrease heart failure hospitalization and decrease mortality in patients with New York Heart Association (NYHA) class 3/4 with depressed systolic function and a prolonged QRS [1-3]. However, 20% ...
Introduction to SR 2
Introduction to SR 2

... 7. Assess the BP and heart rate after each dose of Nitroglycerin administration. 8. Discontinue Nitroglycerin should the BP fall below 140 mmHg, or the heart rate drops below 60 bpm. ...
Atrial Fibrillation Explained - New
Atrial Fibrillation Explained - New

... process begins with a small leak that gradually becomes more severe. These valves can also develop a nodular appearance, which can impede the ability to form a tight seal between the atrium and ventricle during the contraction of the heart. As a result a leak occurs and causes the heart’s chambers t ...
How to diagnose the cause of sudden cardiac arrest
How to diagnose the cause of sudden cardiac arrest

... arrhythmias. This may manifest as additional notching (R’ or S’) or fragmentation of the QRS complexes on surface ECG. Quantitatively defined fragmentation of the QRS complexes based on specific scoring algorithms is associated with increased mortality [14] and arrhythmic events in patients with imp ...
Cardiology Patient Page
Cardiology Patient Page

... followed by the ventricles in a synchronized fashion. In VT, the ventricles beat at a rapid rate, typically from 120 to 300 beats per minute, and are no longer coordinated with the atria. The controlled contraction of the ventricles is important for the heart to pump blood to the brain and the rest ...
Cardiac Biomarkers - Clinician`s Brief
Cardiac Biomarkers - Clinician`s Brief

... Troponin is a protein that regulates interactions between actin and myosin within the sarcomere. This protein leaks into the bloodstream when the cardiomyocyte is disturbed. On the basis of many experimental and clinical studies in animals, cTnI is an excellent marker for myocardial injury because i ...
Fuchsinophilic degeneration of myocardium in patients - Heart
Fuchsinophilic degeneration of myocardium in patients - Heart

Congestive Heart Failure
Congestive Heart Failure

... decreases intravascular volume. Loop diuretics are more effective than other diuretics in the management of acute and chronic heart failure, as well as life-threatening pulmonary edema. In the management of an adult with CHF, an initial dose of furosemide 40  mg IV push should be administered. Once ...
Age Temp Pulse Resp BP Newborn 36.8 axilary 130 (80
Age Temp Pulse Resp BP Newborn 36.8 axilary 130 (80

... - Increases cardiac output. Reduction of BP -dilation of the coronary arteries to improve perfusion of myocardial tissue (particularly helpful when angina is due to coronary artery spasm). -Produces vasodilatation. Helpful with angina - SL- onset 1-3 min, peak unknown, duration 30-60 min -PO-ER- ons ...
Myotrophin is a more powerful predictor of major adverse cardiac
Myotrophin is a more powerful predictor of major adverse cardiac

... MI (myocardial infarction)]; and 19.4 % NSTEMI (non-STEMI)}. Blood measurement was made at 25–48 h after the onset of chest pain. The plasma concentration of myotrophin and NTproBNP was determined using in-house non-competitive immunoassays. Patients were followed-up for the combined end point of de ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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