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High Resolution MR Imaging of the Fetal Heart with Cardiac
High Resolution MR Imaging of the Fetal Heart with Cardiac

... One of the greatest challenges in the fetal MR imaging is the evaluation of the fetal heart. Usually the cardiac imagings in adults are ECG triggered and is made with breathhold of the patient. Since the fetal heart lies within the uterus, a direct triggering of the heart frequency of the fetus is n ...
NAGOYA HEART Study
NAGOYA HEART Study

...  The NHS showed no difference between the valsartan-based and amlodipine-based antihypertensive treatment in terms of preventing composite major cardiovascular outcomes.  Valsartan-based treatment significantly reduced the risk of CHF as compared to amlodipine-based treatment.  Our results will h ...
Managing Atrial Fibrillation - Scioto County Medical Society
Managing Atrial Fibrillation - Scioto County Medical Society

... amiodarone, further reducing the odds for AF recurrence after cardioversion by 45% (p = 0.01) and in patients on medical therapy by 63% (p <0.00001). RAS inhibition is an emerging treatment for the primary and secondary prevention of AF Schneider MP, et. Al. J Am Coll Cardiol. 2010 May 25;55(21):229 ...
Heart Failure - Acute Medicine @ BHH
Heart Failure - Acute Medicine @ BHH

... high dose diuretics increase fluid loss but reduction in circulating volume may cause organ hypoperfusion (e.g. AKI) and increased myocardial stress (activation of RAAS and SNS) ...
Diagnosis and Management of CPVT
Diagnosis and Management of CPVT

... disease is usually absent and the baseline ECG is usually normal however bradycardia and ‘borderline’ QT interval have been reported. Exact prevalence is unknown with estimates of approximately 1:10000. 1.2 Clinical presentation Patients with CPVT often present with exercise- or emotion induced sync ...
Aortic Regurgitation: Time to Reassess Timing of Valve Replacement?
Aortic Regurgitation: Time to Reassess Timing of Valve Replacement?

... more normal ejection fraction and less severe dilation to determine if this technology is helpful in predicting post-operative outcome and, thus, in selecting patients for possible earlier surgery. As the current data suggest a possible role of strain analysis in asymptomatic patients with preserved ...
comparison between the effects of 5 percent hypertonic
comparison between the effects of 5 percent hypertonic

... cells exposed to hyper tonic saline (abstract). Anesthesiology ...
Introduction
Introduction

... Review Following are the important concepts students should come away from this unit and will be contained in the comprehensive unit evaluation test. As a review, define the vocabulary terms in the right column and perform the calculations given. Quiz yourself, or get help on memorizing the items in ...
Endoscopic Ultrasound: New Diagnostic and Therapeutic Applications
Endoscopic Ultrasound: New Diagnostic and Therapeutic Applications

... the latter of which was achieved by improved operator experience and implantation techniques and equipment design modifications. Risks associated with invasive procedures, while infrequent, account for a potential early safety hazard. The risk-benefit ratio of this early safety hazard with the devic ...
Slide 1
Slide 1

... Ca2+ Plateau prolongs the refractory period…..summation cannot happen! Guarantees that Cardiac Muscle Contract-Relaxes Rhythmically!!!!! ...
Electrical Activity of the Heart
Electrical Activity of the Heart

... thinnings called intercalated disks. They have gap junctions which allow action potentials to spread across the syncitium so that they all contract together. 3. Briefly describe the pathways of the heart that subserve the normal orderly passage of electrical activity through it. ...
Arizona Arrhythmia Consultants
Arizona Arrhythmia Consultants

... Laidlaw DW, Brozena S, Jessup ML, Lynn T, Poku J, Ross H, Kocovic D. Survival in patients receiving biventricular pacing for congestive heart failure: Ischemic versus non-ischemic etiology. NASPE Scientific Sessions, May 2003. Chalfoun N, Jessup M, Ross HM, Kocovic, DZ. Biventricular pacing in patie ...
The relationship between aminoterminal propeptide of
The relationship between aminoterminal propeptide of

... necessary. Heart rate variability (HRV) has been recognized as a useful non-invasive method to detect SCD in HF patients (9). Patients with HF had standard deviation (SD) of all normal-to-normal R-R intervals (SDNN) -65.3 ms had higher SCD rate and worse survival during 50 months of follow-up (10). ...
are Mris safe in Patients with cardiac PaceMakers and defribillators?
are Mris safe in Patients with cardiac PaceMakers and defribillators?

... cardiac death due to ventricular arrhythmias. Though initially indicated only for the secondary prevention of sudden death, two landmark trials (MADIT-II and SCD-HeFT) vastly expanded their use to include primary prevention in certain patients with poor cardiac function. As of 2003, an estimated thr ...
Remy Rebeiz Young Heart Foundation
Remy Rebeiz Young Heart Foundation

... Sudden Cardiac Arrest (SCA) or Sudden Arrhythmic Death (SAD) is fatal for children & young adults (ages 12 – 35 years). They can appear healthy & physically fit but may collapse from cardiac arrest without any warning. Most SCA conditions are hereditary. These include “Long QT Syndrome” (LQTS), “Hyp ...
Pharmacology I for dental students Course Description: It
Pharmacology I for dental students Course Description: It

... This is the main indication for the use of vascular smooth-muscle relaxants other than the nitrates. Diastolic hypertension is consequent to increased peripheral resistance, and therefore the rationale for lowering arterial pressure by using drugs that relax vascular smooth muscle is obvious. Previo ...
Supraventricular Tachycardia
Supraventricular Tachycardia

notes - Children`s Heart Clinic
notes - Children`s Heart Clinic

...  Life-long cardiology follow up is necessary for the majority of these patients. If there is no anatomic heart disease, then follow-up can be very infrequent and even as needed in a small minority of patients. Long-Term Outcomes:  Without surgical palliation, 95% of patients with asplenia and 60% ...
Are Clinical Heart Failure and Ejection Fraction Always Connected?
Are Clinical Heart Failure and Ejection Fraction Always Connected?

... Some studies demonstrated that in approximately 40% of the patients with HF, left systolic function is well preserved [16]. This entity was also termed “diastolic HF”. It can be defined as clinical syndrome characterized by the symptoms of heart failure, preserved ejection fraction, and abnormal dia ...
The left atrium: an old `barometer` which can reveal great secrets
The left atrium: an old `barometer` which can reveal great secrets

... Compared with normal subjects, the different components of LA function—reservoir, conduit and active contractile functions—have been shown to be altered in various cardiovascular diseases.9,11 Left ventricular systolic and diastolic dysfunction, elevated filling pressure, LV hypertrophy, mitral regu ...
CV_Physiology_reviewsheet
CV_Physiology_reviewsheet

... The following questions refer to Activity 4: Assessing the Effect of Temperature. 7. List the frog heart rate for the following conditions: _____ bpm with 5°C Ringer’s solution _____ bpm with 32°C Ringer’s solution 8. Describe the effect of temperature on heart rate. ...
discussion worksheets
discussion worksheets

... medulla oblongata (cardioacceleratory center and cardioinibitory center), higher centers of the brain, parasympathetic nervous system (via the Vagus and Hypoglossal nerves) and sympathetic nervous system (via the cardiac nerve and cardiac plexus) interact to influence the heart rate. Also include wh ...
Advanced Technology. Excellent patient care.
Advanced Technology. Excellent patient care.

... resolution and added imaging functionality. MRI has much better soft tissue contrast discrimination than CT and much greater spatial resolution than nuclear medicine by a factor of 10 (1 mm vs. 1 cm). It also has high temporal resolution and a unique ability to visualize turbulence created by valvul ...
Progressive conduction disturbance in myotonic dystrophy
Progressive conduction disturbance in myotonic dystrophy

Left Ventricular Mechanical Support with the Impella during
Left Ventricular Mechanical Support with the Impella during

... Impella device is an attractive alternative in this regard since it is implanted percutaneously without the need for surgical intervention. Also, the forward flow generated by the Impella could prevent potential LV stasis and thrombosis formation. Although only a limited number of studies have evalu ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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