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28 Neural mechanism of heart` regulation
28 Neural mechanism of heart` regulation

... Actine – Act Myosine – My ...
Physiologic Basis and Mechanism of Cardiac Arrhythmias by Dr
Physiologic Basis and Mechanism of Cardiac Arrhythmias by Dr

... Abnormal impulse generation (abnormal automaticity) a. increased automaticity of normally automatic cells (SA, AV, His) b. generation of impulses in normally non-automatic cells - development of phase 4 depolarization in normally non-automatic cells - ‘triggered activity’ due to afterdepolarizations ...
Left Ventricular Mechanical Support with the Impella during
Left Ventricular Mechanical Support with the Impella during

... Impella device is an attractive alternative in this regard since it is implanted percutaneously without the need for surgical intervention. Also, the forward flow generated by the Impella could prevent potential LV stasis and thrombosis formation. Although only a limited number of studies have evalu ...
ICD Implantation Practice Within Europe: How To Explain The
ICD Implantation Practice Within Europe: How To Explain The

... differences in cardiovascular morbidity among countries. ICD implantation rates in each European country may be influenced by economic factors, including the gross domestic product, its percentage devoted to public health, and organization of the health system. However, ICD implantation rates vary s ...
Permanent Pacing Is a Risk Factor for the Development of Heart
Permanent Pacing Is a Risk Factor for the Development of Heart

... significant amount of the time, we would expect to see a lower rate of end points. If anything, this would dilute the effect and result in an underestimate of the relative risk. Third, we were unable to determine the percentage of patients with pacemakers who received only atrial pacing. However, ac ...
Left Ventricular Myxoma Producing Cardiac Failure
Left Ventricular Myxoma Producing Cardiac Failure

... the eighth postoperative day. The left bundle block and the inverse P wave also disappeared. The patient was discharged without any other complications 10 days after the surgery. During follow-up, transthoracic echocardiography examinations at 3, 6, and 12 months after surgery revealed an increase i ...
100 faces of hypertrophy
100 faces of hypertrophy

... and quantify the systolic and diastolic function. New techniques in echocardiography have provided insight into regional myocardial motion and deformation. Tissue Doppler imaging, as well as grayscale 2D speckle tracking, provides more sensitive markers of early myocardial dysfunction compared with ...
File
File

...  Increase or decrease in extracellular K+ decreases heart rate  Effect of body temperature  Heart rate increases when body temperature increases, heart rate decreases when body temperature decreases ...
EUROPACE P 350 of of
EUROPACE P 350 of of

... threshold and oversensing after the shock was found at replacement. Finally two pts had a unipolar ventricular pacing and sensing IDL which was not compatible with the generators available at replacement. In one pt a new pacing and defibrillator lead had to be implanted and in the other only a bipol ...
File
File

... of paper. Groups have one minute to respond (in writing) to each Post-it. ...
New notes
New notes

... 1. The heart is the size of a fist and weighs 250–300 grams. 2. The heart is found in the mediastinum and two-thirds lies left of the midsternal line. 3. The base is directed toward the right shoulder and the apex points toward the left hip. B. Coverings of the Heart (pp. 660–661; Fig. 18.3) 1. The ...
Post-Cardiac Injury Syndrome after Permanent Pacemaker
Post-Cardiac Injury Syndrome after Permanent Pacemaker

... Spindler et al.12 reported 10 similar cases in the literature and subsequently added this case into analysis (n = 11, 8 women and 3 men). Most of his subjects (n = 9, 81.8%) received dual-chamber pacemaker implantation, and active atrial fixation leads were inserted into five patients (45.4%). PCIS ...
Lecture 8 Mercola 2 reduced.pptx
Lecture 8 Mercola 2 reduced.pptx

... •  increased  K+  channel  opening   •  decreased  sinus  node  rhythm   •  decreased  A-­‐V  node   ...
stabilization of the congestive heart failure
stabilization of the congestive heart failure

... In animals with heart failure, dyspnea is the most common presenting complaint in patients presenting to emergency hospitals. Auscultation provides the fist clues in classify the cause of dyspena as due to either heart disease or respiratory disease. Dogs with congestive heart failure are often tach ...
CONSULT ONE
CONSULT ONE

... and peripheral arteries, thus reducing myocardial oxygen demand by decreasing the heart’s rate and contractility. They also limit infarct size and recurrent ischemia and reduce automaticity and malignant arrhythmias such as ventricular tachycardia and ventricular fibrillation. ACE inhibitors improve ...
Nonlinear Cardiac Dynamics
Nonlinear Cardiac Dynamics

experiment-3 study of the effect of various drugs and ions
experiment-3 study of the effect of various drugs and ions

... 3. If the concentrations of ions are abnormal, then the heart will what happen? ...
C h a p t e r   2... ICD : Indian Experience TS Kler , Vanita Arora
C h a p t e r 2... ICD : Indian Experience TS Kler , Vanita Arora

... 11 years after the ICD implantation found that the ICD was associated with a significant decrease in cardiac death compared with amiodarone-treated patients. Patients with the highest risk of SCD benefit most from ICD therapy. CIDS investigators retrospectively stratified the 659 patients into 4 ris ...
EXPERIMENT-3 STUDY OF THE EFFECT OF VARIOUS DRUGS AND …
EXPERIMENT-3 STUDY OF THE EFFECT OF VARIOUS DRUGS AND …

... 3. If the concentrations of ions are abnormal, then the heart will what happen? ...
Meyer P, Filippatos GS, Ahmed MI, Iskandrian AE, Bittner V, Perry
Meyer P, Filippatos GS, Ahmed MI, Iskandrian AE, Bittner V, Perry

... he impact of a reduced left ventricular (LV) ejection fraction (EF) on outcomes in heart failure (HF) is well documented in the literature.1– 4 However, little is known about the impact of a reduced right ventricular (RV) EF on outcomes in chronic systolic HF.5–7 Most studies of RVEF in HF are limit ...
Sudden Cardiac Death Omar M Lattouf MD PHD FACC FACS Heval
Sudden Cardiac Death Omar M Lattouf MD PHD FACC FACS Heval

... Defibrillators (AEDs) in a report on 19,300 witnessed cardiac arrest where patients had dysfunctional rhythms (ventricular tachycardia or ventricular fibrillation) in which AED were used led to 31 % survival rate. (10/26/2015 AHA Releases 2015 Heart and Stroke Statistics | Sudden Cardiac Arrest Foun ...
ECGs and arrhythmia identification
ECGs and arrhythmia identification

... An arrhythmia is any change in rate, rhythm or complex origin that differs from the normal pattern for that individual patient. They may be caused by a multitude of compounding factors including; drug administration, inhalational anaesthetic agents, heart disease, thoracic trauma, age, electrolyte a ...
Rapid and correct diagnosis is critical until a donor heart becomes
Rapid and correct diagnosis is critical until a donor heart becomes

... specialized technique being performed on very sick patients and requires the experience, knowledge and cooperation of the entire team, with each of us bringing to bear our particular area of expertise,” Dr. Tuzcu notes. The procedure begins with insertion of a 22F or 24F sheath in the femoral artery ...
Read the latest ARVD Newsletter
Read the latest ARVD Newsletter

... (n=3), and ICDs (n=28). Among 5 pregnancies, the mothers experienced a single sustained ventricular arrhythmia, 2 of which were terminated by the ICD. Heart failure developed in two pregnancies in women who had already been previously diagnosed with biventricular or right ventricular disease. All in ...
souviner - WCC & IVUS 2015
souviner - WCC & IVUS 2015

... of developing heart disease. Pregnancy related heart diseases require special attention. Older women also require attention as it's never too late to take action to prevent and control the risk factors for heart disease, especially degenerative aortic valve diseases. Even those who have heart diseas ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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