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Cardiovascular Physiology Cardiovascular Physiology
Cardiovascular Physiology Cardiovascular Physiology

NT-proBNP testing - Roche Diagnostics (Schweiz)
NT-proBNP testing - Roche Diagnostics (Schweiz)

... reduction in mortality and rehospitalisation rate. A similar trend towards lower mortality and rehospitalisation rates were also seen in patients in the intermediate group. This suggests that improved patient stratification has the potential to lower mortality and rehospitalisation rates. ...
PDF
PDF

... Pacemaker design has evolved very rapidly over the last several years. There has been a great deal of work in enhancing the programmability of pacemakers, to enable them to be programmed to work with different selected operating parameters, and indeed to work in different modes. In Taiwan, about 70% ...
Cardiac reserve mobilization trend during exercise and recovery
Cardiac reserve mobilization trend during exercise and recovery

... capacity of the myocardium under stress. The study by Hsieh et al. demonstrated that the relative amplitudes of S1 and S2 (aortic component of second heart sound) represent left ventricular dP/dt and ejection fraction (EF) in humans, and S1, corrected for S2, is decreased in patients with impaired L ...
IOSR Journal of VLSI and Signal Processing (IOSR-JVSP)
IOSR Journal of VLSI and Signal Processing (IOSR-JVSP)

... epicardium in a series of cardiac images. Often in clinical practice, the segmentation contours are drawn behind the papillary muscles and trabeculae [8]. Some authors choose to include the trabeculae and papillary muscles as part of the contour. Other authors have adopted the convention that we sho ...
Right Ventricular Involvement In Acute myocardial infarction
Right Ventricular Involvement In Acute myocardial infarction

... individuals presenting with first inferior MI (IMI) and compared individuals with and without concomitant right ventricular infarction [17]. All patients were treated with primary percutaneous coronary intervention, and echocardiography was performed 2–3 days after presentation. The investigators ap ...
Heart Failure with Preserved Ejection Fraction
Heart Failure with Preserved Ejection Fraction

... Heart failure (HF) with preserved left ventricular (LV) ejection fraction (HFpEF) occurs in 40 to 60% of the patients with HF, with a prognosis which is similar to HF with reduced ejection fraction (HFrEF). HFpEF pathophysiology is different from that of HFrEF, and has been characterized with diasto ...
pdf english - International Journal of Cardiovascular Sciences
pdf english - International Journal of Cardiovascular Sciences

... responses in the rest-exercise transition and the identification of the functional capacity include: (1) a precise assessment of the aerobic power, (2) evaluation of cardiometabolic variables at levels of submaximal and maximal effort (e.g.: ventilatory threshold), and (3) evaluation of ventilatory ...
NT-proBNP a cost effective management tool in heart
NT-proBNP a cost effective management tool in heart

... dyspnoeic patients on presentation to the ED.25 Clinical routine care and diagnostic assessment was performed by physicians blinded to NT-proBNP levels. The treatment of patients (clinical examinations performed, medical therapy and period of hospi­ talisation) was retrospectively validated by two i ...
Inotrope Learning Package (Liverpool)
Inotrope Learning Package (Liverpool)

... and venous beds with venous dilatation more predominant.  It is used to reduce systolic, diastolic, and mean arterial pressures and myocardial oxygen consumption.  Peripheral pooling may reduce venous return to the heart, reducing left ventricular end-diastolic pressure (LVEDP) and pulmonary capil ...
Click here to this slideshow
Click here to this slideshow

... – Baseline total cholesterol levels (above vs. below median value; 4.97 mmol/L) • The end point for all the subgroup analyses is the combined outcome measure of all-cause mortality or hospital admission for CV reasons. Adapted from: Tavazzi et al. Eur J Heart Fail 2004;6: 635–41. GISSI-HF Investigat ...
Domperidone: ventricular arrhythmia and sudden death (continued)
Domperidone: ventricular arrhythmia and sudden death (continued)

... 1- Prescrire Editorial Staff “Domperidone: QT prolongation in infants” Prescrire Int 2011; 20 (112): 14. 2- Prescrire Editorial Staff “Domperidone and sudden death” Prescrire Int 2006; 15 (86): 226. 3- Prescrire Editorial Staff “Severe ventricular arrhythmia and sudden death on neuroleptics” Prescri ...
Lecture Notes - Fullfrontalanatomy.com
Lecture Notes - Fullfrontalanatomy.com

... A. The heart is a double pump; the right side pumps blood to the lungs for oxygenation, i.e., the pulmonary circuit; the left side pumps blood throughout the body to nourish tissues, i.e., the systemic circuit (p. 500, Fig. 18.1). B. The four chambers are the right and left atria (receiving chambers ...
Beating Heart Problems
Beating Heart Problems

... more powerful can be the healing. If we treat only the apparent problem without treating its underlying cause one of three things may happen: • New problems may occur • The old problem may recur or persist • Treatments tend to be more difficult, expensive, invasive, and have greater side effects ...
Patient assessment - American Heart Association
Patient assessment - American Heart Association

... changes in the shape of the heart and result in an uncoordinated heartbeat, which is called an arrhythmia (this means a rhythm that is not normal). ...
International Journal of Biomedical Research Research Article
International Journal of Biomedical Research Research Article

... In this retrospective study, a large number of patients with dilated left atrium were documented and this left atrial size correlated with some of the left ventricular dimensions and age of the patients. In a study from Eastern Europe involving 95 patients, the authors found that left ventricular en ...
Opposite Predictive Value of Pulse Pressure and
Opposite Predictive Value of Pulse Pressure and

... Downloaded from http://hyper.ahajournals.org/ by guest on June 16, 2017 ...
Myocardial enterovirus infection with left ventricular
Myocardial enterovirus infection with left ventricular

... transcript of the coxsackievirus B3 viral genome. After hybridization and autoradiography, at least 6 to 10 slides with three to four formaldehyde-fixed biopsy samples were evaluated for the presence of enteroviral genomes. Usually in patients several cells were tested positive. In the case of a sin ...
Can Cardiac Conduction System Disease Be Prevented?
Can Cardiac Conduction System Disease Be Prevented?

... whether patients with existing conduction abnormalities in ALLHAT had a slower progression of disease depending on the randomization limb, if a sufficient number of such patients were present at baseline. Third, the association of lisinopril with reduced incident conduction disease5 was not attribut ...
The physical examination of a child with cardio
The physical examination of a child with cardio

... The cardiac sounds in children are more frequent, more intense (the suckling has more thin thorax), with the tendency to equalization (in suckling). During the child’s growing, the I sound is accentuating on apex, and the II sound - on pulmonary artery, sometimes splitting variably with respiration. ...
Impella 2.5 for haemodynamic support during high-risk
Impella 2.5 for haemodynamic support during high-risk

... myocardial infarction. Impella LD (Left Direct) and Impella RP (Right Percutaneous) are also available but are indicated for use during open chest surgery and for right heart failure respectively. These additional versions and indications are beyond the scope of this briefing. ...
A Clinical Trial of the Angiotensin
A Clinical Trial of the Angiotensin

... Double-blind medication was started between day 3 and day 7 after the myocardial infarction. Patients were randomly assigned to receive 1 mg of trandolapril once daily or matching placebo on the basis of a computer-generated assignment scheme with randomization in blocks of four and stratification ac ...
Slide 1
Slide 1

... The sympathetic nervous system with the release of epinephrine and norephinephrine promotes increased intracellular calcium and thus increased cardiac contractility. Heart rate: refers to the frequency with which the heart beats/contracts to force blood out to the rest of the body’s tissues. As the ...
Full Article - College of Intensive Care Medicine
Full Article - College of Intensive Care Medicine

... Ischaemic hepatitis is not an uncommon complication of cardiac failure and is believed to be due to elevated systemic venous pressure causing hepatic congestion associated with a reduction in hepatic arterial blood flow. The hepatic injury is characterised by centrilobular necrosis in the absence of ...
12_cardio tox
12_cardio tox

... antigenic Fab fragments are discarded, allergic reactions are less than 1% and routine skin testing is unneccessary. Reactions have included erythema, urticaria, and facial edema, all of which are responsive to the usual treatment. Other expected reactions to Fab fragment neutralization of digitalis ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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