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Shift in sleep apnoea type in heart failure
Shift in sleep apnoea type in heart failure

... Follow-up assessments of medications, LVEF, dyspnoea and polysomnographic variables were repeated at 3 and 24 months following randomisation for the entire cohort. For this analysis, the predominant type of sleep apnoea–hypopnoea was determined from the final polysomnogram available in conjunction w ...
Pediatric Anesthesia A Brief Review of Major Topics
Pediatric Anesthesia A Brief Review of Major Topics

... – Insert tube deeply and pull back until fistula is occluded but both lungs are ventilated ...
Similarities and differences between ECG signs of left bundle
Similarities and differences between ECG signs of left bundle

... rS configuration in V1 and V2 that was not different from normal, and notching only in leads II, aVR, and V3. Thus, our simulated ECGs are correctly classified according to their criteria. Figure 2 shows that the implication for CRT is also correct: biventricular pacing only improved ventricular act ...
Teaching Handout – Cardiology 1
Teaching Handout – Cardiology 1

... 1.Therapy Minimise the effect on the patient’s life with the aid of physiotherapy, occupational therapy 2. Support Arrange support from community heart failure nurses and relevant support groups 3. Medical – symptom control: diuretic therapy - long term survival benefit – ace inhibitors (reducing ca ...
rajiv gandhi university of health sciences
rajiv gandhi university of health sciences

... homoeopathic ultra molecular medicine work? And if so how they act when no molecule of the initial substance is present. The question of which diseases respond to homoeopathic treatment is of practical importance.3 So this study characterizes the effect of homoeopathic medicines through the changes ...
P05 - Center for heart failure research
P05 - Center for heart failure research

... in heart failure (HF) of diverse etiologies. However, the physiologic and pathophysiologic roles of myocardial CTGF remain unresolved. Methods and Results: To elucidate the actions of myocardial CTGF and its putative role in HF transgenic mice with cardiac-restricted overexpression of CTGF were gene ...
Chapter 20: The Heart
Chapter 20: The Heart

...  Heart rate is normally established by cells of SA node  Rate can be modified by autonomic activity, hormones, and other factors ...
ARRYTHMIAS AND CONDUCTION DEFECTS IN ECG
ARRYTHMIAS AND CONDUCTION DEFECTS IN ECG

... so rapidly that very little or no blood at all is pumped because there is not enough time between contractions for the ventricles to fill.  When VF occurs, a well-placed electrical shock across the chest may be life saving.  The shock, known as defibrillation, neutralizes all the abnormal electric ...
Management of an adult patient with Truncus arteriosus type I
Management of an adult patient with Truncus arteriosus type I

... 135/80 mm Hg. He was considered to be in class I according to the New York Heart Association (NYHA) classification. He complained of minor reduction in exercise capacity. Comorbidities included mild bronchial asthma and recurrent migraine headaches. He had no family history of congenital heart defec ...
Supracristal Ventricular Septal Defect
Supracristal Ventricular Septal Defect

... Lane R. Miller, MD Margit Nemeth, MD Scott D. Flamm, MD Chung Sung, MD Raymond F. Stainback, MD ...
Mitral Valve Obstruction and Pulmonary Hypertension
Mitral Valve Obstruction and Pulmonary Hypertension

... tumors [2-4]. Primary tumors are relatively rare in the heart and most of them are are benign. Myxomas are the most common accounting for about 50% of all primary tumors and 75% of all benign tumors. Atrial myxoma is a tumor of the heart that occurs primarily in the LA [1]. The clinical signs and sy ...
Cardiopulmonary Physiology
Cardiopulmonary Physiology

... In Figure 6.6, 'equilibrium point' represents the actual value for cardiac output and venous pressure (about 6 l/min and 2 mm Hg in young adults). This equilibrium point is a balancing act between the cardiac performance curve and the vascular performance curve. If cardiac output increases, venous p ...
*How Could Familial Genetic Testing be More Effective in
*How Could Familial Genetic Testing be More Effective in

... raise interests is to see how many symptomatic and nonsymptomatic participants come to find that they contain the mutant gene in their DNA, but have been previously diagnosed with another closely-related condition. Information that is collected during this project will allow for further significant ...
The Heart
The Heart

... • Stroke Volume (SV)– Amount of blood pumped out by one ventricle during each contraction (~70 ml) • Cardiac Output (CO) = Heart Rate (HR) x Stroke Volume (SV) • Let’s do an experiment! ...
Document
Document

... A third degree atrial ventricular block is also know as a complete heart block artrioventricular block of 3degree AV block. It is a problem with electrical conduction. All electrical conduction from the atria are blocked at the AV junction, therefore, the atria and the ventricles beat independently ...
A.L. Wafa`a sameer 2014 Muscles physiology Muscle tissue Types of
A.L. Wafa`a sameer 2014 Muscles physiology Muscle tissue Types of

... In contrast to Sk.m. ( which can be stimulated only by neural stimuli ) Sm.m can be either excited or inhibited by various neural and hormonal stimuli , such as acetyl choline and norepinephrine . Sm.m. classified according to its properties as 1) multiunit 2) visceral ( singleunit ) . However , som ...
Factors in Deciding between Novel and Traditional Oral
Factors in Deciding between Novel and Traditional Oral

... belonging to the family of activated factor X inhibitors were developed, being approved for clinical use by the major drug regulatory agencies around the world after the publication of the following studies: ROCKET-AF (rivaroxaban); 16 ARISTOTLE (apixaban); 17 and, more recently, ENGAGE (edoxaban).1 ...
POSITIVE INOTROPIC ACTVITY OF AQUEOUS EXTRACT OF PERICARP OF PUNICA
POSITIVE INOTROPIC ACTVITY OF AQUEOUS EXTRACT OF PERICARP OF PUNICA

... failure (CHF) on the basis of systolic dysfunction are reflected in the large number of studies on CHF published or presented at meetings in the last two years. While some therapies previously thought to be promising have been shown to be efficacious, others are associated with adverse outcomes, and ...
Download Hopkins Pulse Summer 2014 as a PDF
Download Hopkins Pulse Summer 2014 as a PDF

... ventricles to contract near-simultaneously to pump blood be as simple as up and out of the ventricles and into the lungs and body. adjusting the In people with atrial fibrillation, the electrical impulses device, modifying come from all over the upper chambers. Blood collects in medications the atri ...
ANATOMY AND PHYSIOLOGY TEST: THE HEART
ANATOMY AND PHYSIOLOGY TEST: THE HEART

... ___ 10. What portion of the heart functions as the pacemaker, initiating each heartbeat? A. sinoatrial (SA) node B. atrioventricular (A-V) node C. the neuromuscular junction where the parasympathetic nervous system innervates the heart D. Purkinje fibers E. Bundle of His ___ 11. What does the electr ...
martini_fap7_ch20 revised13
martini_fap7_ch20 revised13

...  Heart rate is normally established by cells of SA node  Rate can be modified by autonomic activity, hormones, and other factors ...
Full Text [Download PDF]
Full Text [Download PDF]

... patients who suffered from acute myocardial infarction and various heart diseases, the HF population is growing rapidly in Taiwan and around the world.1-3 In fact, it is believed that HF is one of the most common causes of hospitalization for elderly patients.4 Many HF patients have multiple comorbi ...
The Evaluation and Management of Electrical Storm
The Evaluation and Management of Electrical Storm

... (LVEF), and New York Heart Association functional class III or IV heart failure.6 Antiarrhythmic agents can precipitate electrical storm.2 Of note, ICD recipients with diabetes mellitus and patients who are taking lipid-lowering drugs reportedly have a lower incidence of electrical storm.17 An imp ...
Congenital complete heart block and spinal anaesthesia for
Congenital complete heart block and spinal anaesthesia for

... bradycardia. The pacemaker rate was set at 50/min in order to preserve her native rhythm till her blood pressure is maintained in the intra‑operative period. Long‑term pacing suppresses the native rhythm, and our intention was to avoid it. Also, the fluoroscopy time for positioning the lead was mini ...
What is Heart Failure? - American Heart Association
What is Heart Failure? - American Heart Association

... Heart failure symptoms usually develop over time as your heart becomes weaker and less able to pump the blood that your body needs. Heart failure usually results in an enlarged heart (left ventricle). ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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