PDF - Circulation: Arrhythmia and Electrophysiology
... switch operations. In the current era, the majority of the adult patients typically have undergone atrial switch operations, either a Senning or a Mustard procedure. Late complications include baffle obstruction, systemic ventricular failure, systemic atrioventricular valve regurgitation, and rhythm ...
... switch operations. In the current era, the majority of the adult patients typically have undergone atrial switch operations, either a Senning or a Mustard procedure. Late complications include baffle obstruction, systemic ventricular failure, systemic atrioventricular valve regurgitation, and rhythm ...
cardiac potassium channel subtypes: new roles in repolarization
... heart works steadily and uninterruptedly, only changing rate according to changes in systemic needs. A human heart thus performs ⬃100,000 successful and coordinated contractions every day. These contractions are controlled by electrical signals, known as action potentials, which trigger an intracell ...
... heart works steadily and uninterruptedly, only changing rate according to changes in systemic needs. A human heart thus performs ⬃100,000 successful and coordinated contractions every day. These contractions are controlled by electrical signals, known as action potentials, which trigger an intracell ...
with abnormalities of atrioventricular conduction Genetic study of
... unexpected death may have been related to disease of the conducting tissue. In family B the propositus had a secundum atrial septal defect with left axis deviation. Both her children had small secundum atrial septal defects. In one there was angiocardiographic evidence of a cleft mitral valve withou ...
... unexpected death may have been related to disease of the conducting tissue. In family B the propositus had a secundum atrial septal defect with left axis deviation. Both her children had small secundum atrial septal defects. In one there was angiocardiographic evidence of a cleft mitral valve withou ...
Interatrial septal thickness as a marker of structural and functional
... fibrosis, and to predict functional remodeling of LA and recurrence rate after AF ablation [7,9]. However, DE-MRI is not routinely available outside of research facilities. Therefore, more widely available and more reproducible noninvasive imaging techniques should be investigated for use in clinica ...
... fibrosis, and to predict functional remodeling of LA and recurrence rate after AF ablation [7,9]. However, DE-MRI is not routinely available outside of research facilities. Therefore, more widely available and more reproducible noninvasive imaging techniques should be investigated for use in clinica ...
No touch vein harvesting technique in coronary by-pass
... This thesis was based on a prospective randomized trial which was started in 1993 to compare the no touch (NT) with the conventional (C) technique of saphenous vein harvesting for CABG. In paper I, was demonstrated superior patency for the NT grafts at short-term (1.5 years; 95,6% vs 89%; p < 0,05) ...
... This thesis was based on a prospective randomized trial which was started in 1993 to compare the no touch (NT) with the conventional (C) technique of saphenous vein harvesting for CABG. In paper I, was demonstrated superior patency for the NT grafts at short-term (1.5 years; 95,6% vs 89%; p < 0,05) ...
Anomalous Origin of the Left Coronary Artery
... The anomaly of the origin of the left coronary artery arising from the pulmonary artery (ALCAPA), was described for the first time in 1885 by Brooks, (1) it is an infrequent and non-lethal congenital heart defect (1 out of 3000 alive newborns) (90% of mortality in the first year of life). In 1993, B ...
... The anomaly of the origin of the left coronary artery arising from the pulmonary artery (ALCAPA), was described for the first time in 1885 by Brooks, (1) it is an infrequent and non-lethal congenital heart defect (1 out of 3000 alive newborns) (90% of mortality in the first year of life). In 1993, B ...
Echocardiography Evaluation of Ventricular Septal Defect
... • Eisenmenger’s complex now rare • Endocarditis most serious complication. Closure of VSD reduces endocarditis risk by 50%. • May develop left heart dilation, aortic regurgitation, or PHTN as patients age • Need to be aware of double chambered RV, subaortic stenosis. Rarely these can develop even af ...
... • Eisenmenger’s complex now rare • Endocarditis most serious complication. Closure of VSD reduces endocarditis risk by 50%. • May develop left heart dilation, aortic regurgitation, or PHTN as patients age • Need to be aware of double chambered RV, subaortic stenosis. Rarely these can develop even af ...
experiments on the origin of auricular flutter and fibrillation
... the difficulties encountered in the experimental production of a paroxysmal auricular tachycardia. It is possible to create this disturbance by the injection of certain substances, such as barium salts, digitalis or strophanthin, or by ligation of a coronary artery. Under these conditions, however, ...
... the difficulties encountered in the experimental production of a paroxysmal auricular tachycardia. It is possible to create this disturbance by the injection of certain substances, such as barium salts, digitalis or strophanthin, or by ligation of a coronary artery. Under these conditions, however, ...
Left Ventricle Assessment-Ejection Fraction and Stroke Volume
... to record and display ultrasound images of 3D. In the beginning of 1990, von Ramm and colleagues developed the first real-time 3D echocardiographic, able of obtain volumetric data at frame rates enough to represent cardiac motion [11]. New ultrasound equipment and techniques allows real-time 3D acqu ...
... to record and display ultrasound images of 3D. In the beginning of 1990, von Ramm and colleagues developed the first real-time 3D echocardiographic, able of obtain volumetric data at frame rates enough to represent cardiac motion [11]. New ultrasound equipment and techniques allows real-time 3D acqu ...
Noninvasive Evaluation of Myocardial Ischemia and Left
... disease in a clinical setting, however, in cases with low CFVR, multiple cardiovascular and metabolic risk factors as well as epicardial coronary artery disease or microvascular dysfunction might be responsible. TTDE is a promising tool, e.g. for follow-up after coronary interventions or for evaluat ...
... disease in a clinical setting, however, in cases with low CFVR, multiple cardiovascular and metabolic risk factors as well as epicardial coronary artery disease or microvascular dysfunction might be responsible. TTDE is a promising tool, e.g. for follow-up after coronary interventions or for evaluat ...
Functional Versus Anatomic Assessment of Myocardial Bridging by
... In addition to the reduced blood flow reserve and decreased blood perfusion derived from delayed arterial relaxation in diastole, progression of atherosclerotic plaque frequently reported in the segment proximal to the MB has been proposed as another potential mechanism of poor clinical outcomes in a ...
... In addition to the reduced blood flow reserve and decreased blood perfusion derived from delayed arterial relaxation in diastole, progression of atherosclerotic plaque frequently reported in the segment proximal to the MB has been proposed as another potential mechanism of poor clinical outcomes in a ...
ECG Monitoring of Myocardial Ischemia for Perioperative
... ventricles (Figure 4). Although repolarization already begins with the ST segment, it becomes visible in the surface ECG only with the beginning of the Twave. The end of the T-wave indicates completed repolarization. The origin of the low amplitude U-wave is still uncertain. It usually has the same ...
... ventricles (Figure 4). Although repolarization already begins with the ST segment, it becomes visible in the surface ECG only with the beginning of the Twave. The end of the T-wave indicates completed repolarization. The origin of the low amplitude U-wave is still uncertain. It usually has the same ...
biphasic defibrillation
... was 86% (compared to pooled reported 63% for damped sine monophasic); three or fewer shocks, 97%; 65% of patients had organized rhythm at hand-off to ALS or ...
... was 86% (compared to pooled reported 63% for damped sine monophasic); three or fewer shocks, 97%; 65% of patients had organized rhythm at hand-off to ALS or ...
PDF
... Material and methods: Between December 2004 and December 2013, 300 patients with medical record of VSD were admitted to our study, previously admitted to the cath lab at our center for percutaneous treatment of their VSD with various types of devices. All patients were followed until December 2013, ...
... Material and methods: Between December 2004 and December 2013, 300 patients with medical record of VSD were admitted to our study, previously admitted to the cath lab at our center for percutaneous treatment of their VSD with various types of devices. All patients were followed until December 2013, ...
Noninvasive electrocardiographic imaging for cardiac
... the left bundle branch (LBB) only; (iii) right-ventricular (RV) and left-ventricular (LV) pacing (subject P), an example of the ability of ECGI to image ventricular arrhythmias of focal origin, and to locate arrhythmogenic foci (simulated by pacing sites) or exit sites of reentry pathways during ven ...
... the left bundle branch (LBB) only; (iii) right-ventricular (RV) and left-ventricular (LV) pacing (subject P), an example of the ability of ECGI to image ventricular arrhythmias of focal origin, and to locate arrhythmogenic foci (simulated by pacing sites) or exit sites of reentry pathways during ven ...
Impact of Definitions of Left Ventricular Hypertrophy on Left
... (1) Assessment of cardiac structure: LV mass was determined by the formula: 0.8[1.04(LVDD + IVST + PWT)3 - LVDD3] + 0.6 g, where LVDD = left ventricular end-diastolic diameter, IVST = diastolic interventricular septal thickness, and PWT = diastolic posterior wall thickness.13 RWT was also determined ...
... (1) Assessment of cardiac structure: LV mass was determined by the formula: 0.8[1.04(LVDD + IVST + PWT)3 - LVDD3] + 0.6 g, where LVDD = left ventricular end-diastolic diameter, IVST = diastolic interventricular septal thickness, and PWT = diastolic posterior wall thickness.13 RWT was also determined ...
and Cavity Size: An Analysis of 1500 Human Hearts
... chronic lung disease with large right ventricles and relatively small left ventricles, but there were not enough patients to alter the relationship. Because the noninfarction group also included patients who died of cancer rather than coronary disease there was a relatively greater number of small h ...
... chronic lung disease with large right ventricles and relatively small left ventricles, but there were not enough patients to alter the relationship. Because the noninfarction group also included patients who died of cancer rather than coronary disease there was a relatively greater number of small h ...
No Slide Title
... Axis refers to the mean QRS axis (or vector) during ventricular depolarization. As you recall when the ventricles depolarize (in a normal heart) the direction of current flows leftward and downward because most of the ventricular mass is in the left ventricle. We like to know the QRS axis because an ...
... Axis refers to the mean QRS axis (or vector) during ventricular depolarization. As you recall when the ventricles depolarize (in a normal heart) the direction of current flows leftward and downward because most of the ventricular mass is in the left ventricle. We like to know the QRS axis because an ...
Coronary artery-left ventricular microfistulae associated with apical
... Thebesian venous system; or there can be a common etiologic factor, such as a genetic mutation resulting in both anomalies. Both coronary artery fistulae and AHC can cause angina pectoris and their association may aggravate the clinical condition. Increased oxygen demand due to myocardial hypertroph ...
... Thebesian venous system; or there can be a common etiologic factor, such as a genetic mutation resulting in both anomalies. Both coronary artery fistulae and AHC can cause angina pectoris and their association may aggravate the clinical condition. Increased oxygen demand due to myocardial hypertroph ...
Assessment of Myocardial Fibrosis With Cardiovascular Magnetic
... (3), and others being progressive and potentially reversible, as in hypertensive cardiomyopathy (4). Myocardial fibrosis in animal and patient studies is associated with worsening ventricular systolic function, abnormal cardiac remodeling, and increased ventricular stiffness (5–7). In recent clinica ...
... (3), and others being progressive and potentially reversible, as in hypertensive cardiomyopathy (4). Myocardial fibrosis in animal and patient studies is associated with worsening ventricular systolic function, abnormal cardiac remodeling, and increased ventricular stiffness (5–7). In recent clinica ...
Remote Ischemic Conditioning for the Reduction of Ischemia
... spontaneous reperfusion may have potentially diluted the beneficial effects of RIC. The presence of collateral blood flow to the area at risk in the left ventricle, which would be expected to reduce myocardial infarct size, was also not controlled for in this study. No differences in major adverse c ...
... spontaneous reperfusion may have potentially diluted the beneficial effects of RIC. The presence of collateral blood flow to the area at risk in the left ventricle, which would be expected to reduce myocardial infarct size, was also not controlled for in this study. No differences in major adverse c ...
An Analysis of the Mechanical Disadvantage of Myocardial Infarction
... model will be reduced to a level adequate to calculate ventricular stroke volume, but not adequate to determine such dynamic quantities as the time course of rising ventricular pressure. The model we begin here attempts to represent the ventricle only at end-ejection, when the contraction velocity i ...
... model will be reduced to a level adequate to calculate ventricular stroke volume, but not adequate to determine such dynamic quantities as the time course of rising ventricular pressure. The model we begin here attempts to represent the ventricle only at end-ejection, when the contraction velocity i ...
Presentation (PowerPoint File) - IPAM
... Why does it matter? The recent recognition that up to 50% of patients admitted to hospitals with congestive heart failure have ‘normal systolic function’ as reflected by ejection fraction, has further emphasized the need to more fully understand the physiology of diastole. UCLA/IPAM 2/6/06 ...
... Why does it matter? The recent recognition that up to 50% of patients admitted to hospitals with congestive heart failure have ‘normal systolic function’ as reflected by ejection fraction, has further emphasized the need to more fully understand the physiology of diastole. UCLA/IPAM 2/6/06 ...
American College of Cardiology/European Society of Cardiology
... Indeed, in most patients, management strategies have traditionally been tailored to the hemodynamic state. Outflow gradients are responsible for a loud apical systolic ejection murmur associated with a constellation of unique clinical signs,14,72,111 hypertrophy of the basal portion of ventricular s ...
... Indeed, in most patients, management strategies have traditionally been tailored to the hemodynamic state. Outflow gradients are responsible for a loud apical systolic ejection murmur associated with a constellation of unique clinical signs,14,72,111 hypertrophy of the basal portion of ventricular s ...
Pulsus paradoxus - European Respiratory Journal
... Inspiratory increase in lung volume Effects on right ventricular afterload The relationship between lung vessels resistance and lung volume is complex. From a series arrangement viewpoint, the pulmonary circulation may be divided into extra-alveolar vessels and intra-alveolar vessels [6]. Inspirator ...
... Inspiratory increase in lung volume Effects on right ventricular afterload The relationship between lung vessels resistance and lung volume is complex. From a series arrangement viewpoint, the pulmonary circulation may be divided into extra-alveolar vessels and intra-alveolar vessels [6]. Inspirator ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.