• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Cardiac Murmurs
Cardiac Murmurs

... area is reduced from 3 to 4 cm2 to 1.5 to 2 cm2. However, an additional reduction in t he valve area from half its normal size to a quarter of it’s normal size produces severe obstruction to flow and progressive pressure overload on the left ventricle. ...
Automatic External Defibrillators (AED)
Automatic External Defibrillators (AED)

... functions. Through electrodes placed on the patient's chest, the AED unit senses and analyzes the cardiac rhythm of the heart and makes a decision based upon that information. Semi-automated devices require more decision making on the operator's part. If defibrillation is indicated, the unit will th ...
Does prior coronary stenting compromise future coronary surgery?
Does prior coronary stenting compromise future coronary surgery?

... CAD; however, they also have more advanced symptoms and carry greater urgency. The most recent multicenter study on the subject from Mannacio et al. investigated the impact of previous PCI on postoperative outcome and 5-year survival after subsequent CABG [23] . A total of 7855 consecutive patients ...
Atrial and visceral situs inversus with congenitally corrected
Atrial and visceral situs inversus with congenitally corrected

... MRI[6] may be helpful in confirming other associated anomalies. A chest X-ray and ultrasonography of the abdomen are necessary to diagnose visceral situs. Left ventricular outflow tract obstruction can be relieved with a transannular patch in patients with atrial situs inversus with congenitally cor ...
Does This Patient Have Aortic Regurgitation?
Does This Patient Have Aortic Regurgitation?

... There are 3 important areas to auscultate for diastolic murmurs. Area 1 is the second and third intercostal spaces at the right-sternal border. Area 2 is the second and fourth intercostal spaces at the left-sternal border. Aortic regurgitation murmurs may be heard in both areas 1 and 2. If the murmu ...
Pericarditis Guide
Pericarditis Guide

... your doctor may prescribe medications to offset gastrointestinal symptoms. If you are taking high doses of nonsteroidal anti-inflammatory drugs, you should be monitored with frequent follow-up appointments to evaluate changes in kidney or liver function. A small number of patients will develop chron ...
View
View

... presentations to Frimley for syncope. Syncope is a symptom not a disorder in itself; it may be caused by a large number of diseases (see Box 1) which range from benign to potentially life-threatening conditions. Syncope may present diagnostic difficulties and it has been estimated that initial ED hi ...
Cardiac sympathetic innervation via middle cervical and stellate
Cardiac sympathetic innervation via middle cervical and stellate

... channelopathies, including long QT syndrome and catecholaminergic polymorphic ventricular tachycardia, who have structurally normal hearts (4, 17, 38). In a small series of patients with structural heart disease, bilateral CSD has shown promise in reducing the burden of internal cardioverter defibri ...
Quantification of left and right atrial kinetic energy using four
Quantification of left and right atrial kinetic energy using four

... importance of the conservation of KE in the looped heart has recently been under debate (24, 39, 40). Recent studies have demonstrated rotational flow patterns in atrial blood and suggested that this arrangement may be beneficial for energy conservation (14, 23). However, the energy involved in rota ...
AFA Ablation for AF Booklet.indd
AFA Ablation for AF Booklet.indd

... procedure. Sometimes it is impossible to tell if these adverse effects are linked to the procedure or just coincidence. In other words, it would not have been mentioned as a potential complication during the consent process prior to the procedure. An example of an unintended consequence could be the ...
Use of the AED - Berridge Medical Training
Use of the AED - Berridge Medical Training

... Implanted devices Some heart patients may have a pacemaker or defibrillator implanted. These can usually be seen or felt just below the left collar bone, which is not normally in the way of the pads so care must be taken not to place pads over them. Supplemental oxygen There are no reports of fires ...
TITLE: Risk assessment of QT prolongation with escitalopram and
TITLE: Risk assessment of QT prolongation with escitalopram and

... including RCTs, crossover trials, and a cohort study were found to address the cardiovascular risk of each agent. Available studies indicate a dose related lengthening of the QTc interval with both antidepressants, suggesting that these agents should be used at lower doses in patients with risk fact ...
cpr + aed programme - Singapore General Hospital
cpr + aed programme - Singapore General Hospital

... This procedure can frequently re-start the heart if carried out early. Studies have shown that early defibrillation is most likely to improve survival rates for out-ofhospital cardiac arrest patients. Every emergency vehicle transporting cardiac arrest patients should be equipped with a defibrillato ...
Clinical and echocardiogram profile of Cardiomyopathy at tertiary
Clinical and echocardiogram profile of Cardiomyopathy at tertiary

... Background: Cardiomyopathies represent a heterogeneous group of diseases that often lead to progressive heart failure with significant morbidity and mortality. The improved recognition or of other factor, the incidence and prevalence of heart failure due to cardiomyopathy appears to be increasing. A ...
28 Ejection Clicks
28 Ejection Clicks

Print - Circulation
Print - Circulation

... With left atrial injection the base of the left ventricle and the aortic valve are obscured. Therefore, the long axis of the ventricular cavity is measured from its apex to the intersection of its left anterior margin with the corresponding margin of the left atrium (or in a few patients, of the aor ...
2015 Heart Rhythm Society Expert Consensus Statement on the
2015 Heart Rhythm Society Expert Consensus Statement on the

... Society, in collaboration with representatives from the American Autonomic Society (AAS), the American College of Cardiology (ACC), the American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), the European Heart Rhythm Association (EHRA), the Pediatric and Congenital Electroph ...
6 Heart Sounds
6 Heart Sounds

... In the past, many theories have been advanced to explain the origins of sounds during the cardiac cycle. These included simple concepts of sound originating from the actual contact of valve cusps upon closure. When it was realized that the strength of contraction of the left ventricle had a signific ...
2015 Heart Rhythm Society Expert Consensus Statement on the
2015 Heart Rhythm Society Expert Consensus Statement on the

... variance among 4 published reports.9,12,14,15 Most patients present with POTS between the ages of 15 and 25 years,7 and more than 75% are female.7–9,11–14,16 POTS is also common in patients with chronic fatigue syndrome.17 The chronic and usually systemic symptoms and the frustration caused by the d ...
General Questions about AEDs 1. What does AED stand for?​ AED
General Questions about AEDs 1. What does AED stand for?​ AED

... Survival. They can restore a normal heart rhythm in victims of sudden cardiac arrest. New,  portable AEDs enable more people to respond to a medical emergency that requires  defibrillation. When a person suffers a sudden cardiac arrest, their chance of survival decreases  by 7% to 10% for each minut ...
Ranolazine Reduces Remodeling of the Right Ventricle and
Ranolazine Reduces Remodeling of the Right Ventricle and

... 2013). Pathologic processes that are known to increase late INa (Voelkel et al., 2012; Freund-Michel et al., 2013; Shryock et al., 2013; Toischer et al., 2013) are also implicated in the progression of RV failure in PAH (Voelkel et al., 2012; FreundMichel et al., 2013; Shryock et al., 2013; Toischer ...
Cardiac Effects of Acute Ethanol Ingestion Unmasked
Cardiac Effects of Acute Ethanol Ingestion Unmasked

... normal subjects, age 20-35 years, using M-mode echocardiography and systolic time intervals. On day 1, measurements were made of heart rate, mean velocity of circumferential fiber shortening, and left ventricular preejection period and left ventricular ejection time ratio (PEP/LVET), during a contro ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... switch operations. In the current era, the majority of the adult patients typically have undergone atrial switch operations, either a Senning or a Mustard procedure. Late complications include baffle obstruction, systemic ventricular failure, systemic atrioventricular valve regurgitation, and rhythm ...
Correlation Between ST‐Segment Elevation and Negative T Waves
Correlation Between ST‐Segment Elevation and Negative T Waves

... be associated with significant morbidity and mortality. Prompt and proper diagnosis and therapy is of paramount significance to reduce mortality. APE is often misdiagnosed as acute coronary syndrome because of the similarity of the presenting symptoms and of the electrocardiogram (ECG) manifestation ...
Intercellular Coupling Abnormalities in the Heart: Quantification from
Intercellular Coupling Abnormalities in the Heart: Quantification from

... Cardiac conduction velocity is one of the most important electrophysiological characteristics of the heart. Several cardiac dysfunctions and arrhythmia are caused by slowed conduction velocity. Measurement of cardiac conduction velocity and other physiological characteristics of the heart such as an ...
< 1 ... 36 37 38 39 40 41 42 43 44 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report