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References
References

... as an induction agent and inj. Vecuronium 4mg as a muscle relaxant. Following an uneventful induction CVP line was secured in right upper extremity. Anaesthesia was maintained on O2 + N2O + Sevoflurane + intermittent inj. Vecuronium on closed circuit on controlled mechanical ventilation. Intraoperat ...
Full paper
Full paper

... importance of at least 3 months of postoperative antiarrhythmic medication to achieve the maximum success rate for the ablation procedure. 16 In our study, 2 patients with postoperative persistent AF had restor- ation of sinus rhythm after 3 months. Many factors afect the success rate of RF ablation ...
- Value in Health
- Value in Health

... men), with a median age of 61 years (interquartile range 50 –71 years). Thirty-seven percent of patients had ischemic heart disease as the HF etiology; 87% were currently taking beta blockers, and 91% were taking angiotensin converting enzyme inhibitors. The prevalence of diabetes mellitus in this c ...
Changes in lipid profile of patients referred to a cardiac rehabilitation
Changes in lipid profile of patients referred to a cardiac rehabilitation

... ECG, the prevalence of CVD was significantly higher among Iranian women than Iranian men [27]. In a prospective study in which patients who received lipidlowering drugs were excluded, The HDL and LDL fractions did not change significantly after completion of a CRP including a combination of general ...
Text - Ulster Institutional Repository
Text - Ulster Institutional Repository

... acute coronary occlusion, i.e. STEMI, not detected by 12L ECG are more likely to undergo a delayed revascularisation strategy and are thus at increased risk of an adverse prognosis. To date, the 12L ECG remains the initial bedside investigation in the triage of patients presenting with acute ischaem ...
A Case Series of Lyme Carditis with Complete Heart Block
A Case Series of Lyme Carditis with Complete Heart Block

... Chronic cases of Lyme have led to dilated cardiomyopathy in Europe, but there have been no reported cases of cardiomyopathies secondary to Lyme disease in the US.1,7 The most common cardiac manifestation of Lyme disease is fluctuating AV block.1-3,5 Almost all (98%) adults with Lyme carditis will ma ...
Cardiorespiratory effects of breathing and relaxation instruction in
Cardiorespiratory effects of breathing and relaxation instruction in

... carried out in the initial period of the study, but also either because some measurements did not yield adequate recordings, or patients did not return for the follow-up measurement. All patients had survived a recent myocardial infarction, 24 (32%) had a large infarction (EG 26%, CG 38%), 26 (34%) ...
compnay reports
compnay reports

... Medtronic is Top Brand in ICDs. Medtronic (56%) is easily the most recognized brand in the implantable defibrillator market today, according to our respondents, followed by Guidant (12%) and St. Jude Medical (6%). ...
Heart Notes and Questions
Heart Notes and Questions

... Generally speaking, the __________________ division of the autonomic nervous system tells the heart to relax, slow down, and take it easy, while the ____________________ division tells the heart to ____________________ . Also, adrenaline, produced by the ___________________ glands can tell the heart ...
Invasive and non-invasive methods for cardiac output measurement
Invasive and non-invasive methods for cardiac output measurement

... A B S T R A C T : The hemodynamic status monitoring of high-risk surgical patients and critically ill patients in Intensive Care Units is one of the main objectives of their therapeutic management. Cardiac output is one of the most important parameters for cardiac function monitoring, providing an e ...
Not All Angiotensin-Converting Enzyme Inhibitors
Not All Angiotensin-Converting Enzyme Inhibitors

... bradykinin binding sites compared with other ACE inhibitors (Table 1; Figure 1, 2). Moreover, unlike enalapril, no titration is needed with perindopril treatment to provide the patient with maximal antihypertensive effect.9 Additionally, enalapril,9,10 which can lead to underperfusion of target orga ...
Electrocardiography II. Determination of the cardiac axis Analyis and
Electrocardiography II. Determination of the cardiac axis Analyis and

1 HEART DISEASE Cardiovascular disease is a class of diseases
1 HEART DISEASE Cardiovascular disease is a class of diseases

... 7. The balloon is then inflated, and it compresses the atheromatous plaque and stretches the artery wall to expand. 8. If an expandable wire mesh tube (stent) was on the balloon, then the stent will be implanted (left behind) to support the new stretched open position of the artery from the inside. ...
22 Physiological properties of heart
22 Physiological properties of heart

... Automatism of heart - the ability of cells of the heart conducting system to produce independently bioelectric impulses, that cause its excitement.  Structures of conducting system have different degrees of automaticity. It is established the so-called gradient of automaticity . It manifests itself ...
Physiology Ch. 10 p115-120 [4-25
Physiology Ch. 10 p115-120 [4-25

... -After sudden AV bundle block, purkinje system does not begin to emit intrinsic rhythmical impulses until 5-20s later because before blockage, purkinje system was overdriven by rapid sinus impulses and are in a suppressed state -ventricles fail to pump during these 5-20 seconds, and person faints af ...
Heart and Pericardium
Heart and Pericardium

... 1. Surface of the heart is usually covered with variable amounts of fat 2. Apex of the heart a. Formed by the inferolateral part of the left ventricle b. Located downward and to the left along a point approximately 9 cm from the midline, in the left 5th intercostal space in adults c. Remains motionl ...
VF / Pulseless VT
VF / Pulseless VT

... • If VF/VT persists after 1 or 2 shocks plus CPR, give Epinephrine 1mg q3-5 min. • When VF/pulseless VT persists after 2-3 shocks plus CPR and vasopressor, consider antiarrhythmic. • Rhythm checks should be brief, and pulse checks should generally be performed only if an organized rhythm is observe ...
Heart murmurs - Australian Doctor
Heart murmurs - Australian Doctor

... ◗◗ Anaemia (low iron in the blood) ◗◗ Hormone imbalances (such as hyperthyroidism) ◗◗ Heart surgery. Children commonly develop innocent heart murmurs at some point during infancy or childhood and these are usually harmless and go away as the child gets older. Abnormal heart murmurs during childhood ...
CAUSE: Cardiac arrest ultra-sound exam
CAUSE: Cardiac arrest ultra-sound exam

... for experienced practitioners manual is dedicated to this topic and its practical application.2 Hughes et al. provided a list of the etiologies of PEA in the order of frequency and ease of reversal.3 He lists the top five conditions as hypoxia, hypovolemia, tension pneumothorax, pericardial tamponad ...
Effect of resting heart rate on two-year clinical outcomes of high
Effect of resting heart rate on two-year clinical outcomes of high

... asymptomatic aortic stenosis (AS)8. In addition, it was recently demonstrated that sympathetic nervous system (SNS) activity is increased and arterial baroreflex is impaired in patients with AS undergoing transcatheter aortic valve implantation (TAVI)9. A high HRate reflects an increase in SNS activ ...
Exercise and Physical Activity for the Post-
Exercise and Physical Activity for the Post-

... severe emotional stress, respectively, immediately prior to dissection. In another series by Hatzaras et al,3 31 patients (30 men, 1 woman; mean age, 47.3 years) were identified (mean aortic diameter of 4.6 cm on initial imaging) who were engaged in weight training or heavy lifting at dissection ons ...
J Thorac Cardiovasc Surg. 2009 Jul
J Thorac Cardiovasc Surg. 2009 Jul

... compared across categories using chi-square or Fisher exact test, and continuous variables were compared across groups using analysis of variance and Tukey post hoc testing if the differences were statistically significant. All P values are 2-tailed tests. ...
Unit One: Introduction to Physiology: The Cell and General Physiology
Unit One: Introduction to Physiology: The Cell and General Physiology

Cardio-vascular Physiology 3
Cardio-vascular Physiology 3

... base of the heart  mean electrical axis of the ventricles. In standard leads: determine the net potential and polarity of the recordings. Net potential for a lead obtained after subtracting the negative potential from the positive part of the potential. Then each net potential is plotted on the axe ...
Cardiovascular System: Pulmonary circuit: right ventricle → lungs
Cardiovascular System: Pulmonary circuit: right ventricle → lungs

... Coronary artery disease -partial or complete block of coronary circulation, results in coronary ischemia Can lead to myocardial infarction (heart ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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