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Understanding Heart Failure – The Basics
Understanding Heart Failure – The Basics

... the body to the lungs. In the lungs, your blood is loaded up with oxygen. The left side of the heart pumps ‘fresh’ blood full of oxygen from the lungs to the rest of the body. The left side of the heart is usually the larger than the right. That is because it has to pump hard to get the blood out to ...
Hyperglycemia Increases New-Onset Atrial Fibrillation in Patients
Hyperglycemia Increases New-Onset Atrial Fibrillation in Patients

... those patients admitted to Taipei Veterans General Hospital of Taiwan due to acute STEMI from May 2007 to June 2009. A total of 307 consecutive patients without any documented AF prior to admission were included in this study based on the registration of the coronary care unit (CCU) of Taipei Vetera ...
Heart
Heart

... Greater force of contraction can increase stroke volume & the greater amount of blood pumped in one minute Two ways stroke volume can be affected: ...
Comparative Hemodynamic Effects of Inotropic and
Comparative Hemodynamic Effects of Inotropic and

... by at least 3-4 fold. Concentration of the infusate was adjusted so that at no time did infusion rate exceed 1.4 ml per minute. The order of drug infusions was varied, and 30-60 minutes was allowed after completion of one drug infusion before the other was instituted. Cardiac output (CO) was calcula ...
Arrhythmias and sport practice
Arrhythmias and sport practice

... Whether sudden death would have been avoided or delayed if they had avoided intense endurance training cannot be known, but it seems evident that older individuals should be carefully evaluated before and during their engagement in intense endurance training, whether competitive or not. Figure 2 sho ...
Prognostic Importance of Defibrillator Shocks in Patients with Heart
Prognostic Importance of Defibrillator Shocks in Patients with Heart

... ter Automatic Defibrillator Implantation Trial II (MADIT II) both showed that therapy with implantable cardioverter–defibrillators (ICDs) improves survival among patients who are at risk for sudden cardiac death but who have not previously had a sustained ventricular arrhythmia.1-3 On the basis of t ...
General Audience - ABcomm, Inc. Home
General Audience - ABcomm, Inc. Home

... Impact of RV Function on Therapy • RV function can highlight the subtle changes in early disease and prompt rapid initiation of therapy • RV function determines the patient’s functional capacity and survival • Deterioration in RV function mirrors disease progression ...
Spontaneous resolution of sinoatrial exit block and atrioventricular
Spontaneous resolution of sinoatrial exit block and atrioventricular

... investigated for underlying myocarditis. The creatinine phosphokinase (CPK) and lactate dehydrogenase (LDH) levels were 172 U/dL (normal ≤ 130 U/dL) and 776 potassium and calcium levels were found to be normal. ...
Mitral ValVe - Advocate Health Care
Mitral ValVe - Advocate Health Care

... ventricle (lower, pumping chamber). Diseases of the mitral valve can range in severity: Mitral valve prolapse occurs when the flaps in the valve are unable to close properly. While mitral valve prolapse does not always require treatment, it can lead to a condition called mitral valve incompetence wh ...
SYZYGIUM CUMINI ISOLATED SMOOTH MUSCLE STRIP AND HEART  Full Proceeding Paper
SYZYGIUM CUMINI ISOLATED SMOOTH MUSCLE STRIP AND HEART Full Proceeding Paper

... tension of the lever was adjusted such that it gives maximum contraction. The responses produced by the tissue were recorded in the kymograph instrument (INCO AMBALA, India). The extract was added and the respective heart rate and force of contraction were measured with time. RESULTS In the isolated ...
Heart Failure - Fort Sanders Regional Medical Center
Heart Failure - Fort Sanders Regional Medical Center

... A test that is given while a patient walks on a depends on how much of the heart’s pumping treadmill or pedals a stationary bike to monitor capacity has been lost. the heart during exercise. Breathing and blood The symptoms of heart failure may resemble other pressure rates are also monitored. A s ...
Diastolic Heart Failure - STA HealthCare Communications
Diastolic Heart Failure - STA HealthCare Communications

... on the ECG and an X-ray showing signs of heart failure with a normal cardiac silhouette. An echocardiogram was performed and showed a normal size LV cavity with significant concentric LVH, an ejection fraction of 65% and signs of grade 3 (severe or “restrictive physiology”) diastolic dysfunction. Th ...
Quality of Care for Atrial Fibrillation Among Patients
Quality of Care for Atrial Fibrillation Among Patients

... consecutive eligible HF patients to the GWTG-HF registry. Hospital teams used HF case-ascertainment methods similar to those of the Joint Commission. All participating institutions were required to comply with local regulatory and privacy guidelines and, if required, to secure institutional review b ...
Reduced cardiac volumes in chronic fatigue
Reduced cardiac volumes in chronic fatigue

... those with CFS have a primary cardiac abnormality that accounts for at least some of their symptoms. These symptoms include orthostatic intolerance which limits the patient’s functional capacity and predicts their quality ...
Heterogeneous responses of systolic and diastolic left ventricular
Heterogeneous responses of systolic and diastolic left ventricular

... pathophysiologies has only recently been introduced to target recruitment of relevant subgroups into clinical studies investigating therapies aimed at specific underlying mechanisms of the disease.18,19 In clinical practice, these patients are diagnosed by criteria established by the European Society ...
9. Prerequisites course
9. Prerequisites course

... 1. The main causes of pulmonary heart. 2. What is hypercapnia, and acidosis. 3. Clinical and instrumental features compensated pulmonary heart. 4. The clinical picture of decompensated pulmonary heart. ...
Failure to prescribe anticoagulation (PDF 377K)
Failure to prescribe anticoagulation (PDF 377K)

... cardioversion to treat her atrial fibrillation and ordered that a trans-oesophageal echocardiogram (TOE) be carried out before the procedure to check for existing cardiac thrombus. The results of the TOE were normal and a successful cardioversion was performed under the same sedation and with hepari ...
Prognosis assessment of persistent left bundle branch
Prognosis assessment of persistent left bundle branch

... complete left bundle branch block (LBBB) by direct lesion of the LBB of His. This block can lead to highgrade atrioventricular conduction disturbances responsible for a poorer prognosis. The management of this complication remains controversial. Method and analysis: The screening of LBBB after TAVI ...
Race and Sex Differences in QRS Interval and Associated Outcome
Race and Sex Differences in QRS Interval and Associated Outcome

ECG TUTORIAL: How to Analyze A Rhythm - sha
ECG TUTORIAL: How to Analyze A Rhythm - sha

... • is an atrial arrhythmia that occurs when the natural cardiacpacemaker site shifts between the sinoatrial node (SA node), the atria, and/or the atrioventricular node (AV node). • In an accessory conduction pathway is present between the atria and the ventricles. • Electrical impulses are rapidly co ...
The Heart is not a Pump
The Heart is not a Pump

... there would be no fluid pressure left after the capillaries that open into the tissues. Furthermore, there is more blood volume in the veins than the arteries, by a wide (65% to 12%) margin; an efficient pump design would operate on the larger volume directly. -The relationship between flow and pres ...
paten t du ctus art eriosus: surgical complications, morbidity and
paten t du ctus art eriosus: surgical complications, morbidity and

... complications have been reported following surgical closure. Chylothorax may rarely occur due to injury to the thoracic duct during dissection or manipulation of the ductusY Treatment usually consists of tube thoracostomy drainage and replacement of lost nutrients and surgical intervention is rarely ...
opinions and hypotheses
opinions and hypotheses

... to coronary artery disease, are also encouraging.1,2,12,19,23–27 A major ongoing prospective, nonrandomized, multicenter study of ventricular resynchronization2 is being conducted in patients with NYHA class III/IV drug-refractory CHF, left ventricular dysfunction (left ventricular ejection fraction ...
Mitral Valve Replacement and Remodeling of the Left Ventricle in
Mitral Valve Replacement and Remodeling of the Left Ventricle in

... demonstrated that this pathology accounts for two thirds of the treatments for cardiovascular disease. When medical treatment does not afford sufficient improvement and the heart failure becomes refractory, surgical approaches can be used in selected cases to change the clinical evolution. Heart tra ...
61 Case Report SUDDEN DEATH DUE TO VENTRICULAR SEPTAL
61 Case Report SUDDEN DEATH DUE TO VENTRICULAR SEPTAL

... presented frequently with breathing difficulties died suddenly and VSD with cardiomegaly was diagnosed at autopsy. [7]. There are studies which suggest that patients with VSD have impaired sexual life in both sexes but especially in males who reports a larger incidence of erectile dysfunction.[8]On ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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