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Survival Benefit of Aortic Valve Replacement in Patients With Severe
Survival Benefit of Aortic Valve Replacement in Patients With Severe

... reluctance to offer aortic valve replacement (AVR). Methods. Our echocardiographic database for the period of 1993 to 2003 was screened for severe AS (aortic valve area [AVA] < 0.8 cm2) with LVEF 0.35 or less or a mean transvalvular gradient of 30 mm Hg or less. Chart reviews were performed for clin ...
Anisotropic Reinforcement of Acute Anteroapical Infarcts Improves
Anisotropic Reinforcement of Acute Anteroapical Infarcts Improves

... Background—We hypothesize that a therapy that improves left ventricular (LV) pump function early after infarction should decrease the need for compensation through sympathetic activation and dilation, thereby reducing the risk of developing heart failure. The mechanical properties of healing myocard ...
Medline search : references : 1996-2009
Medline search : references : 1996-2009

... ventricular (LV) enlargement in endurance trained subjects and QTd is unknown. The cloning of the angiotensin-converting enzyme (ACE) gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. The aim of this study was to a ...
Importance of the Conal Branch of the Right Coronary Artery
Importance of the Conal Branch of the Right Coronary Artery

... coronary circulation, James (22) noted that the LAD might supply varying degrees of the right ventricular free wall. He also noted that the right paraseptal region was supplied by the first big septal branches of the LAD alone or together with the conal branch of the right coronary artery (RCA) (the ...
Distinguishing between those dying suddenly or
Distinguishing between those dying suddenly or

... no high-risk MRC codes for left ventricular hypertrophy. Minnesota codes 6, 7 and 8 were not shown in the MRC publication, and high-risk ECG abnormalities were agreed by the authors. (In fact, these abnormalities were assigned to very few study participants.) Participants were followed up for up to ...
Left Ventricular Untwisting Is an Important Determinant of Early
Left Ventricular Untwisting Is an Important Determinant of Early

... are related to parameters of early diastolic filling but not events happening later in diastole. Reductions in the rate and magnitude of untwisting were associated with worsening of diastolic relaxation and reduced early diastolic suction. These findings lend further weight to the hypothesis that un ...
Copyright (c) 2009, Radiological Society of North America, Inc
Copyright (c) 2009, Radiological Society of North America, Inc

... Clinical Indication: [#] year old [woman |man] with coronary artery disease risk factors of [hyperlipidemia; hypertension; diabetes; autoimmune disease; prior MI; prior stroke; smoking history; family history of heart disease] presenting with [exertional angina; atypical chest pain; chronic chest pa ...
SECTION 2
SECTION 2

... identify areas of myocardial ischemia, injury, or infarction. By doing this, the most appropriate treatment can be given. The ECG cannot stop a heart attack, nor can it reperfuse areas of ischemic myocardium; fibrinolytic medications (clot-busters) and invasive procedures (eg, cardiac catheterizatio ...
Objective and Subjective Analysis of Left Ventricular
Objective and Subjective Analysis of Left Ventricular

... The percentage decrease in area for the anterior, inferior and combined apical segments was then determined for each patient. This method of assessing hypokinesis does not require the actual superimposition of the ventricular silhouettes, but has the same effect as superimposing them along the long ...
Endocardial wave front organization during ventricular
Endocardial wave front organization during ventricular

... deviation) were studied. Patient characteristics are shown in Table 1. Electrode 1 of the catheter was always in an antero-basal position, and electrode 36 of the catheter was always in a postero-basal position. An example of recorded electrograms from the 36-pole catheter is shown in Figure 2. Surf ...
PDF - Circulation: Arrhythmia and Electrophysiology
PDF - Circulation: Arrhythmia and Electrophysiology

... A 68-year-old man with nonischemic dilated cardiomyopathy, first-degree heart block (PR 320ms), left bundle-branch block (LBBB; QRS 200 ms; Figure 1, left panel), and severe left ventricular dysfunction had a biventricular defibrillator implanted 3 years ago. His heart failure symptoms were well con ...
Integrated analysis of atrioventricular interactions in - AJP
Integrated analysis of atrioventricular interactions in - AJP

... was calculated by subtracting the minimal atrial volume from the maximal atrial volume at middiastole. Conduit volume resulted after subtraction of the sum of reservoir and pump volume from effective stroke volume of the LV. The terms “systole” and “diastole” always refer to ventricular systole and ...
Assessment of left ventricular diastolic function by early diastolic
Assessment of left ventricular diastolic function by early diastolic

... An additional group of 60 consecutive patients who were undergoing right heart catheterization in the cardiac catheterization laboratory (n ⫽ 25) or the intensive care unit (n ⫽ 35) was included. All were in sinus rhythm (60 –100 beats/min) and with satisfactory Doppler and pressure recordings and n ...
Effect of changes in contractility on the index of myocardial
Effect of changes in contractility on the index of myocardial

... following 4 weeks of oral digoxin. Results: With chronic left ventricular dysfunction, a reduced left ventricular ejection fraction (42 ± 3%, p < 0.001) and increased index of myocardial performance (0.58 ± 0.17, p < 0.01) due to isovolumic contraction time lengthening and shortened left ventricular ...
The Effect Vagus Nerve Stimulation Vulnerability
The Effect Vagus Nerve Stimulation Vulnerability

... ventricle. Evidence to the contrary has recently been provided by Kent and Harrison et al.5' 6 When the ventricular fibrillation (VF) threshold was determined by means of a train of electrical pulses closely coupled to an antecedent paced beat, it was found that both VNS5 and edrophonium chloride" c ...
Progressive Left Ventricular Dysfunction and
Progressive Left Ventricular Dysfunction and

... predictors of survival in patients after myocardial infarction. Prospective studies relating progressive ventricular enlargement in individual patients to global and regional cardiac dysfunction and the onset of late chronic heart failure are not available. It was the aim of this study to define the ...
Syncope - UC Irvine`s Department of Medicine
Syncope - UC Irvine`s Department of Medicine

... ◦ Somewhat more helpful than Holter ◦ Limitations in that patient must be conscious to activate unit and record rhythm when symptomatic ◦ Some models (intermittent) can store several minutes of recording which pt can activate on regaining consciousness. ◦ Reccs- Indicated for patients who have clini ...
Mean pulmonary arterial pressure after percutaneous mitral
Mean pulmonary arterial pressure after percutaneous mitral

... Introduction and aim: Percutaneous mitral valvuloplasty (PMV) is an effective treatment option for mitral stenosis (MS), but its success is assessed on the basis of clinical and echocardiographic outcomes in studies with relatively short follow-up. We aimed to characterize a cohort of patients under ...
STG- TAVI seminar-DR. SANDEEP MOHANAN
STG- TAVI seminar-DR. SANDEEP MOHANAN

... • Concomitant CAD : SVD/ TVD • Surgical Risk : STS-PROM at 30days - Low : <4% - Intermediate: 4-8% - High: >8-15% - Prohibitive : >15%, >50% all-cause mortality risk at 1 year , porcelain aorta, prior radiation, post bypass surgery with adherent grafts to chest wall, ≥3 major organ dysfunction ...
Anomalous left coronary artery from the pulmonary artery (ALCAPA
Anomalous left coronary artery from the pulmonary artery (ALCAPA

... The patient who underwent Takeuchi procedure developed mild right ventricle outlet obstruction gradient. At this time, however, surgical procedure is not indicated REVIEW Despite its rarity, this anomaly has been extensively studied, since Brook’s first description in 1886.4 In 1908, Abbot described ...
Dobutamine Increases Cardiac Output
Dobutamine Increases Cardiac Output

... Ohio State University. The model consisted of nine calves that underwent replacement of the native right and left ventricles with pneumatically driven total artificial right and left ventricles (Jarvik 7, Symbion, Inc., Salt Lake City, or Utah 100, University of Utah, Salt Lake City). The procedure ...
Left Ventricular Diastolic Function in Patients With
Left Ventricular Diastolic Function in Patients With

... two groups of patients. Flattening of the interventricular septum during systole suggesting right ventricular pressure overload was also observed with similar frequency in the two groups, as was the presence of significant tricuspid regurgitation (mild or greater, by color Doppler echocardiography). ...
Full Text
Full Text

... Carpentier et al. (29) made the major contribution of suggesting quadrangular resection of redundant posterior leaflet segments (Fig. 1B). By undermining the remaining posterior leaflet segments, more than one-half of the posterior leaflet can be resected. This “sliding leaflet plasty” reduces the h ...
Cardiac Auscultation: Rediscovering the Lost Art
Cardiac Auscultation: Rediscovering the Lost Art

... “innocent” murmur with only trivial or mild (“physiologic”) valvular regurgitation detected by color-flow Doppler techniques. Cardiac auscultation should not become a lost art, or the stethoscope a medical relic. Despite the current emphasis on technology, the cardiac stethoscopic examination, when ...
California Board of Registered Nursing CEP#15122
California Board of Registered Nursing CEP#15122

... Knowledge of hemodynamic parameters in the heart is important to understanding disease processes, interventions, and drug treatments. Hemodynamics is the movement of the blood and the forces involved. To understand this concept, you need to know about preload, afterload, and cardiac output. These co ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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