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Thrombolytics in Cardiac Arrest
Thrombolytics in Cardiac Arrest

... Van de Werf F, Bax J, Betriu A, et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation. The Task Force on the management of ST-segment elevation actue myocardial infarction of the European Society of Cardiology. Eur Heart J 2008; 29: ...
Increased Superoxide Radical with a Decrease in Vascular
Increased Superoxide Radical with a Decrease in Vascular

... creased in developing pressure-overload myocardial hypertrophy. The expressions of VEGF and iNOS mRNA were then increased in the early stage of hypertrophy, but decreased in the late stage. The LVH models used in this experiment were created by abdominal aortic banding, as we had previously reported ...
ECG in Ventricular arrhythmias
ECG in Ventricular arrhythmias

... PVCs are significant for two reasons. 1, they can lead to more serious arrhythmias, such as ventricular tachycardia or ventricular fibrillation. The risk of developing a more serious arrhythmia increases in patients with ischemic or damaged hearts. 2,PVCs also decrease cardiac output, especially if ...
Left Main Coronary Artery Stenosis after Aortic Valve Replacement
Left Main Coronary Artery Stenosis after Aortic Valve Replacement

... open-heart surgery. J Thorac Cardiovasc Surg 1969; 57: 792795. 3. Midell AI, De Boer A, Bermudez G: Postperfusion coronary ostial stenosis: incidence and significance. J Thorac Cardiovasc Surg 1976; 72: 80-85. 4. Betocchi S, Miceli D, Giudice P, et al: Iatrogenic ostial stenosis of the left coronary ...
Arrhythmia post heart transplantation
Arrhythmia post heart transplantation

... or loss of SR after HTx can be due to any reason and can lead to serious hemodynamic problems. Ischemia reperfusion injury, unbalanced serum electrolytes and re-warming of cold myocardial tissue are known to initiate arrhythmia during the period of reperfusion after implantation of the heart graft. ...
Evaluation of Bi-ventricular Coronary Flow Patterns Using High
Evaluation of Bi-ventricular Coronary Flow Patterns Using High

... ischemia (Tarnavski et al. 2004). The mouse with TAC has been used to induce pressure overload to the left ventricle for observation and intervention of the ventricular remodeling (Rockman et al. 1991). The flow dynamics of all coronary arteries at different stages after TAC would provide valuable i ...
Bicuspid Aortic Valve - Annals of Thoracic and Cardiovascular Surgery
Bicuspid Aortic Valve - Annals of Thoracic and Cardiovascular Surgery

... usually oriented right and left with the true commissures oriented anterior and posterior, but may also be in an anteroposterior orientation. Most commonly, the right and left coronary leaflets comprise the larger, fused leaflet and the noncoronary leaflet is separate with true commissures. The free ...
PDF Full-text
PDF Full-text

... continuous flow LVADs in comparison with pulsatile flow devices [8] and confirmed its increasing trend [9]. Durability issues are closely related to driveline infection and failure, thrombosis and haemolysis, and ultimately pump drive unit failure. The decision to insert a device is complex and must ...
Aortic annular measurements in fresh post
Aortic annular measurements in fresh post

... Our findings of mean aortic annular diameter being greater in males than females are supported by literature [5, 7, 8]. Accordingly men have valves that are 10 % larger than women [7]. Age related dilatation of the aortic root has been consistently reported which substantiates our finding [7, 8, 9]. ...
cardiogenic shock-management - The Association of Physicians of
cardiogenic shock-management - The Association of Physicians of

... in the noninfarction zone because of metabolic abnormalities. It is important to recognize that large areas of nonfunctional but viable myocardium can also cause or contribute to the development of cardiogenic shock in patients after myocardial infarction. Cardiogenic shock can also be caused by mec ...
Conventional and biventricular pacing in patients with first
Conventional and biventricular pacing in patients with first

... mechanical left AV synchrony, a situation where a pacingcontrolled AV delay would not be expected to produce further haemodynamic improvement.7 Implantation of a conventional dual-chamber pacemaker may improve cardiac performance on a short-term basis in a minority of patients with severe HF, first- ...
Impairment of coronary flow reserve in aortic stenosis
Impairment of coronary flow reserve in aortic stenosis

... myocardial ischemia in AS patients, and this may contribute to the development of LV dysfunction, symptoms, and adverse outcomes (34). There still persist some uncertainties and controversies as to the mechanisms underlying the impairment of CFR in AS patients (12). The concentric LV hypertrophy typ ...
Left ventricular systolic/diastolic function evaluated by quantitative
Left ventricular systolic/diastolic function evaluated by quantitative

... were compared with those by ultrasound echocardiography (UCG) and also with plasma B-type natriuretic peptide (BNP) concentrations. Methods: We examined 46 patients with various forms of heart disease. By the QGS data with 16 framing data acquisition using technetium (Tc)-99m methoxyisobutylisonitri ...
Cardiac Malpositions
Cardiac Malpositions

... arteries arising from the morphologic left ventricle. The conus anatomy in this situation is variable but is usually bilate.rally deficient. It should be noted that as used herein DORV differs from the broader use proposed by Lev,' i.e., aorta and pulmonary artery completely or almost completely ari ...
Aortic fat pad and atrial fibrillation: cardiac lymphatics revisited
Aortic fat pad and atrial fibrillation: cardiac lymphatics revisited

... stenosis/atresia), the principal lymphatic trunks can be easily damaged. During these operations, special care should be taken when dissecting and mobilizing the MPA for reconstruction of the right ventricular outflow tract. It may lead to similar complications to those observed after the Fontan pro ...
Seminars in Cardiothoracic and Vascular Anesthesia
Seminars in Cardiothoracic and Vascular Anesthesia

... free-radical-scavenging properties as well as the related inhibition of the mitochondrial permeability transition pore. For intravenous anesthesia, propofol is always combined with an opioid. Opioids have relatively few cardiovascular side effects and, in particular, do not cause myocardial depressi ...
Pericardial Disease - Society of Cardiovascular Anesthesiologists
Pericardial Disease - Society of Cardiovascular Anesthesiologists

... pericardium at the diaphragm, at the atrial level and around the great vessels provide restraint to this structure in that expansion beyond these pericardial reflections is inhibited if the heart increases in size; the tough fibrous quality of the parietal pericardium contributes to the pericardium’ ...
Seminars in Cardiothoracic and Vascular Anesthesia
Seminars in Cardiothoracic and Vascular Anesthesia

... free-radical-scavenging properties as well as the related inhibition of the mitochondrial permeability transition pore. For intravenous anesthesia, propofol is always combined with an opioid. Opioids have relatively few cardiovascular side effects and, in particular, do not cause myocardial depressi ...
Pathophysiology and Therapy for Atrial Septal Defects
Pathophysiology and Therapy for Atrial Septal Defects

... in patients with evidence of right atrial or right ventricular enlargement, even in the absence of symptoms.1 This recommendation for closure in the asymptomatic patient is derived from an understanding of cardiac hemodynamics, shunt physiology, and the indolent natural history of ASDs. In hearts wi ...
New Diagnostic and Therapeutic Possibilities For Diastolic Heart
New Diagnostic and Therapeutic Possibilities For Diastolic Heart

... mellitus. Of note, diastolic dysfunction is observed in about Echocardiographic speckle tracking 40% of patients with diabetes.5 These risk factors have conDeveloping methods for diagnosis of diastolic dysfunction siderable overlap with atherosclerosis, which suggested that include assessing left ve ...
Is transcatheter aortic valve implantation cost effective in the
Is transcatheter aortic valve implantation cost effective in the

... Transcatheter heart valves are an emerging technology for the treatment of patients with aortic stenosis (AS). The procedure is widely known as either transcatheter aortic valve implantation (TAVI) or replacement. Unlike surgical aortic valve replacement (AVR), which is the standard treatment for pa ...
mechanisms of cardiac septation and valve development
mechanisms of cardiac septation and valve development

... A mature mammalian heart has four valves and four chambers, with the wall of each chamber consisting of three tissue layers: endocardium, myocardium and epicardium (Fig. 1). The cardiac chambers and valves are organized such that they separate systemic from pulmonary circulation and ensure direction ...
Relationship between 24- hour Holter variables, chest discomfort
Relationship between 24- hour Holter variables, chest discomfort

... syncope and Holter variables. The latter finding could indicate that 24-hour Holter monitoring may not be an ideal or first hand choice for evaluation of syncope in a non emergent, outpatient setting. Furthermore, some of the the 24-hour heart rate profiles appear to be similar between subjects with ...
Effect of Acutely Increased Right Ventricular Afterload on Work
Effect of Acutely Increased Right Ventricular Afterload on Work

... Left ventricular stroke work, the energy output from the left ventricular chamber during contraction, has recently been shown to be a linear function of the end-diastolic volume in conscious dogs.32 If the effects of altered right ventricular loading conditions on left ventricular systolic function ...
PDF
PDF

... for muscular VSD (VSDM) [3], since in the gold standard treatment for the perimembranous VSD is surgical closure with the use of extracorporeal circulation [4-7,8,9-11,12-17,18-21]. Aside that due to the high rate of complications reported on initial experiences for percutaneous procedures to close ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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