New Targets to Treat the Structural Remodeling of the
... is increasing recognition of diffuse interstitial and perivascular myocardial fibrosis (i.e., reactive fibrosis) occurring either in regions remote to the infarct or as a separate entity in a variety of conditions in the absence of infarct, including hypertensive heart disease, diabetic cardiomyopat ...
... is increasing recognition of diffuse interstitial and perivascular myocardial fibrosis (i.e., reactive fibrosis) occurring either in regions remote to the infarct or as a separate entity in a variety of conditions in the absence of infarct, including hypertensive heart disease, diabetic cardiomyopat ...
Cardiogenic Shock
... diminished left ventricular preload, even with normal left ventricular contractility, causes a decreased systemic cardiac output. The right ventricle also becomes dilated, which results in displacement of the intraventricular septum to the left. If severe, this can actually impair left ventricular f ...
... diminished left ventricular preload, even with normal left ventricular contractility, causes a decreased systemic cardiac output. The right ventricle also becomes dilated, which results in displacement of the intraventricular septum to the left. If severe, this can actually impair left ventricular f ...
cardiac masses - NT Cardiovascular Center
... Symptomatic only in the aortic position (other than embolic Sx) Ostial occlusion angina, sudden death Rarely valvular dysfunction Source of embolization in up to 30% of patients ...
... Symptomatic only in the aortic position (other than embolic Sx) Ostial occlusion angina, sudden death Rarely valvular dysfunction Source of embolization in up to 30% of patients ...
Atrial Flutter
... times in patients with heart failure and 1.9 times in those with chronic obstructive lung disease Unusual to occur in a normal heart, and is especially uncommon in children and young ...
... times in patients with heart failure and 1.9 times in those with chronic obstructive lung disease Unusual to occur in a normal heart, and is especially uncommon in children and young ...
coronary artery anomalies DR SANMATH
... Atherosclerosis in myocardial bridge IVUS in 69 patients with myocardial bridge found increased incidence of atherosclerosis at segments proximal to the bridge, but no plague within or distal to the bridges. Ge J, Jeremias A, Rupp A, et al. New signs characteristic of myocardial bridging demonstrat ...
... Atherosclerosis in myocardial bridge IVUS in 69 patients with myocardial bridge found increased incidence of atherosclerosis at segments proximal to the bridge, but no plague within or distal to the bridges. Ge J, Jeremias A, Rupp A, et al. New signs characteristic of myocardial bridging demonstrat ...
Full text (PDF file)
... involved in LV activation, the LV deformation starts at the points where RV and LV leads are attached to the myocardium, and in the upper septal or anteroseptal area activated by the intrinsic system. From the theoretical point of view, the maximum intraventricular synchronization is achieved by min ...
... involved in LV activation, the LV deformation starts at the points where RV and LV leads are attached to the myocardium, and in the upper septal or anteroseptal area activated by the intrinsic system. From the theoretical point of view, the maximum intraventricular synchronization is achieved by min ...
The effect of connexin40 deficiency on ventricular conduction
... on a rather small number of analysed hearts, we felt that a systematic, quantitative overview of mouse embryonic activation patterns was due, and would likely uncover similar variability, as did our earlier chicken studies. Conduction through the cardiac tissue is determined by the tissue geometry ( ...
... on a rather small number of analysed hearts, we felt that a systematic, quantitative overview of mouse embryonic activation patterns was due, and would likely uncover similar variability, as did our earlier chicken studies. Conduction through the cardiac tissue is determined by the tissue geometry ( ...
Transcatheter Closure of Post-operative Residual Ventricular Septal
... the delivery cable, after which it still sat nicely across the defect. When the angiogram was repeated, the position was found to be stable, but other residual VSDs were identified. Our attempt to cross the other residual VSDs using a guide wire and a JR catheter was unsuccessful. Finally, we decide ...
... the delivery cable, after which it still sat nicely across the defect. When the angiogram was repeated, the position was found to be stable, but other residual VSDs were identified. Our attempt to cross the other residual VSDs using a guide wire and a JR catheter was unsuccessful. Finally, we decide ...
Full Text - Res Cardiovasc Med
... tool for the measurement of left ventricular ejection fraction (EF) and volumes, which are of great importance in the management and follow-up of patients with coronary artery diseases. However, considering the technical shortcomings of SPECT in the presence of perfusion defect, the accuracy of this ...
... tool for the measurement of left ventricular ejection fraction (EF) and volumes, which are of great importance in the management and follow-up of patients with coronary artery diseases. However, considering the technical shortcomings of SPECT in the presence of perfusion defect, the accuracy of this ...
Targeting Reactive Oxygen Species Production To Prevent Left
... not well understood and currently, no medical therapy exists to treat this condition. Cardiac VO is marked by eccentric remodeling and contractile dysfunction ultimately resulting in cardiac failure. Oxidative stress is implicated in the pathophysiology of heart failure and recent evidence suggests ...
... not well understood and currently, no medical therapy exists to treat this condition. Cardiac VO is marked by eccentric remodeling and contractile dysfunction ultimately resulting in cardiac failure. Oxidative stress is implicated in the pathophysiology of heart failure and recent evidence suggests ...
Adverse Effect of Ventricular Pacing on Heart Failure and
... time to event as the dependent variable and Cum%VP as a timedependent covariate. HFH models were extended to include multiple HFHs by use of Cox models that allow multiple events per patient.6 Both unadjusted models (Cum%VP as the only predictor) and adjusted models (adjusted for other known baselin ...
... time to event as the dependent variable and Cum%VP as a timedependent covariate. HFH models were extended to include multiple HFHs by use of Cox models that allow multiple events per patient.6 Both unadjusted models (Cum%VP as the only predictor) and adjusted models (adjusted for other known baselin ...
BE III PG 1-5
... The first step is to evaluate the P waves. P waves indicate whether the atrial rhythm is normal. For proper diagnosis of an ECG, technicians should ask themselves the following questions: Are the P waves occurring at regular intervals? Do the P waves all have the same appearance on the ECG? Are the ...
... The first step is to evaluate the P waves. P waves indicate whether the atrial rhythm is normal. For proper diagnosis of an ECG, technicians should ask themselves the following questions: Are the P waves occurring at regular intervals? Do the P waves all have the same appearance on the ECG? Are the ...
some aspects of left ventricular remodeling in patients with chronic
... renal failure. Concentric hypertrophy with the most common in patients with CKD III-IV, and eccentric hypertrophy frequency increases with the progression of CKD. At a certain stage in the development of chronic renal failure hypertrophy of LV has adaptive value by increasing the wall thickness of L ...
... renal failure. Concentric hypertrophy with the most common in patients with CKD III-IV, and eccentric hypertrophy frequency increases with the progression of CKD. At a certain stage in the development of chronic renal failure hypertrophy of LV has adaptive value by increasing the wall thickness of L ...
Arterial stiffness: insights from Framingham and Iceland
... ARTERIAL STIFFNESS AND PRESSURE PULSATILITY The gold-standard measure of aortic stiffness is carotid–femoral PWV (CFPWV), which is optimally assessed by using arterial tonometry (Fig. 1). ...
... ARTERIAL STIFFNESS AND PRESSURE PULSATILITY The gold-standard measure of aortic stiffness is carotid–femoral PWV (CFPWV), which is optimally assessed by using arterial tonometry (Fig. 1). ...
PEEP and cardiac output
... The effects of PEEP on LV preload are dependent on changes in systemic venous return, right ventricular output and left ventricular filling. Owing to the complexity of these changes, the single factors will be discussed separately. Determinants of venous return The sensitivity of systemic venous ret ...
... The effects of PEEP on LV preload are dependent on changes in systemic venous return, right ventricular output and left ventricular filling. Owing to the complexity of these changes, the single factors will be discussed separately. Determinants of venous return The sensitivity of systemic venous ret ...
Approach to Dextrocardia in Adults: Review
... tus. Thus, in situs solitus with formation of an L-bulboventricular loop (instead of the normal D-bulboventricular loop), the right-sided morphologic right atrium connects to a right-sided morphologic left ventricle, and the left-sided morphologic left atrium drains to a left-sided morphologic right ...
... tus. Thus, in situs solitus with formation of an L-bulboventricular loop (instead of the normal D-bulboventricular loop), the right-sided morphologic right atrium connects to a right-sided morphologic left ventricle, and the left-sided morphologic left atrium drains to a left-sided morphologic right ...
Quantification of left and right atrial kinetic energy using four
... Image analysis and KE calculation. Images were analyzed using an in-house-developed module for the image analysis software Segment (http://segment.heiberg.se) (17). A first-order polynomial fit to stationary tissue was used to compensate for eddy currents and other phase background effects. Velocity ...
... Image analysis and KE calculation. Images were analyzed using an in-house-developed module for the image analysis software Segment (http://segment.heiberg.se) (17). A first-order polynomial fit to stationary tissue was used to compensate for eddy currents and other phase background effects. Velocity ...
Is It Reasonable to Treat All Calcified Stenotic Aortic Valves
... VS ⴝ valved stent and all patients gave their informed consent. A braided nitinol self-expandable stent from Laboratoires Perouse (Ivry-le-Temple, France) was used for intraoperative aortic valve “stenting.” The stent was designed specifically for endovascular valve replacement (5). Its diameter at ...
... VS ⴝ valved stent and all patients gave their informed consent. A braided nitinol self-expandable stent from Laboratoires Perouse (Ivry-le-Temple, France) was used for intraoperative aortic valve “stenting.” The stent was designed specifically for endovascular valve replacement (5). Its diameter at ...
PDF ansehen - Deutsches Herzzentrum München
... Access to excellent congenital heart surgery is essential. This does not need to be in your own institution, but it certainly needs to be accessible. This includes the entire surgical team and intensive care personnel. The most common ACHD surgical procedure is pulmonary valve replacement. In my opi ...
... Access to excellent congenital heart surgery is essential. This does not need to be in your own institution, but it certainly needs to be accessible. This includes the entire surgical team and intensive care personnel. The most common ACHD surgical procedure is pulmonary valve replacement. In my opi ...
An Analysis of the Mechanical Disadvantage of Myocardial Infarction
... predicts ventricular function in the infarcted heart when compared to clinical information and available ventricular models of higher complexity. Computations based on finite element solutions of this membrane model yield end-diastolic and end-systolic pressure-volume curves, from which ventricular ...
... predicts ventricular function in the infarcted heart when compared to clinical information and available ventricular models of higher complexity. Computations based on finite element solutions of this membrane model yield end-diastolic and end-systolic pressure-volume curves, from which ventricular ...
The right ventricle in pulmonary arterial hypertension
... (3 months) aortic–pulmonary shunting in piglets. However, RV–arterial coupling deteriorated with a decrease in the Emax/Ea ratio because of an insufficient adaptive increase in Emax in late endotoxic shock, monocrotaline-induced pulmonary hypertension, long-term (6 months) aortic–pulmonary shunting ...
... (3 months) aortic–pulmonary shunting in piglets. However, RV–arterial coupling deteriorated with a decrease in the Emax/Ea ratio because of an insufficient adaptive increase in Emax in late endotoxic shock, monocrotaline-induced pulmonary hypertension, long-term (6 months) aortic–pulmonary shunting ...
2005 and 2010 Guidelines for First Aid - CPR
... Evidence from radiologic studies of the chest in children suggests that compression to one half the anterior-posterior diameter may not be achievable. However, effective chest compressions require pushing hard, and based on new data, the depth of about 1 ½ inches (4 cm) for most infants and about 2 ...
... Evidence from radiologic studies of the chest in children suggests that compression to one half the anterior-posterior diameter may not be achievable. However, effective chest compressions require pushing hard, and based on new data, the depth of about 1 ½ inches (4 cm) for most infants and about 2 ...
The importance of exercise echocardiography for clinical decision
... stress and the immediate postexercise period,22 specifically regarding the SPAP. After the patient is positioned on the ergometer, a workload of 50 W is set. During the test, the workload is increased with 25 W every 3 min in young, otherwise healthy patients, but can be adjusted in older individual ...
... stress and the immediate postexercise period,22 specifically regarding the SPAP. After the patient is positioned on the ergometer, a workload of 50 W is set. During the test, the workload is increased with 25 W every 3 min in young, otherwise healthy patients, but can be adjusted in older individual ...
Cardiac Remodeling in Response to 1 Year of Intensive - MET-TEST
... of endurance athletes are a result of exercise training or a genetically determined characteristic of talented athletes. We hypothesized that prolonged and intensive endurance training in previously sedentary healthy young individuals could induce cardiac remodeling similar to that observed cross-se ...
... of endurance athletes are a result of exercise training or a genetically determined characteristic of talented athletes. We hypothesized that prolonged and intensive endurance training in previously sedentary healthy young individuals could induce cardiac remodeling similar to that observed cross-se ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.