Isovolumetric Relaxation?
... Several studies have been performed in patients with a variety of myocardial diseases that have identified a prolongation of r. However, it is not clear whether prolongation of represents abnormal myocardial physiology or the effect of excessive load associated with a particular disease process. Acc ...
... Several studies have been performed in patients with a variety of myocardial diseases that have identified a prolongation of r. However, it is not clear whether prolongation of represents abnormal myocardial physiology or the effect of excessive load associated with a particular disease process. Acc ...
Brain responses to cardiac electrical stimulation: a new - J
... Nihon Kohden, Tokyo, Japan) and were digitized at a sampling rate of 1,000 Hz. EEGs and ECGs were band-pass-filtered at 0.01-100 Hz and 0.01-500 Hz, respectively. All activity was referenced to electrodes of the both ear lobes and grounded with an electrode on the forehead. An electro-oculogram was ...
... Nihon Kohden, Tokyo, Japan) and were digitized at a sampling rate of 1,000 Hz. EEGs and ECGs were band-pass-filtered at 0.01-100 Hz and 0.01-500 Hz, respectively. All activity was referenced to electrodes of the both ear lobes and grounded with an electrode on the forehead. An electro-oculogram was ...
Dispersion of QT and QRS in Patients with Severe Congestive Heart
... heart diseases. High values of QT dispersion reflect an inhomogeneity of the repolarization time of the ventricular myocardium that may be the substrate for the development of malignant ventricular arrhythmias 1,2. At the same time, pharmaceutical agents with a proven anti-arrhythmic effect, such as ...
... heart diseases. High values of QT dispersion reflect an inhomogeneity of the repolarization time of the ventricular myocardium that may be the substrate for the development of malignant ventricular arrhythmias 1,2. At the same time, pharmaceutical agents with a proven anti-arrhythmic effect, such as ...
Cardiac Computed Tomographic Angiography
... high positive predictive value and specificity but only moderate sensitivity for presence of acute or healed MI. Additional studies conclude that the presence and size of early perfusion defects and late enhancement on cardiac CTA is closely related to follow-up segment myocardial dysfunction and my ...
... high positive predictive value and specificity but only moderate sensitivity for presence of acute or healed MI. Additional studies conclude that the presence and size of early perfusion defects and late enhancement on cardiac CTA is closely related to follow-up segment myocardial dysfunction and my ...
Valvular Heart Disease
... pressure gradient and to calculate valve area during a baseline state and again during exercise or low-dose pharmacological (i.e., dobutamine infusion) stress, with the goal of determining whether stenosis is severe or only moderate in severity. Such studies can be performed in experienced echocardi ...
... pressure gradient and to calculate valve area during a baseline state and again during exercise or low-dose pharmacological (i.e., dobutamine infusion) stress, with the goal of determining whether stenosis is severe or only moderate in severity. Such studies can be performed in experienced echocardi ...
Cardiac Computed Tomographic Angiography
... Intravenous iodinated contrast agents used for cardiac CTA have also received FDA approval. Prospective studies with small sample sizes conclude that cardiac CTA is a promising noninvasive method for assessment of coronary stents, detection of in-stent restenosis and occlusion, and for evaluating by ...
... Intravenous iodinated contrast agents used for cardiac CTA have also received FDA approval. Prospective studies with small sample sizes conclude that cardiac CTA is a promising noninvasive method for assessment of coronary stents, detection of in-stent restenosis and occlusion, and for evaluating by ...
A rare case of cardiac anomaly: prenatally diagnosed ectopia cordis
... right ventricular diverticle, double outlet right ventricle and more rarely with single ventricle, transposition of the great arteries and atrioventricular septal defect (1, 7, 9, 11). In addition, extracardiac disorders including omphalocele, gastrochisis, scoliosis, cleft lip-palate and central ne ...
... right ventricular diverticle, double outlet right ventricle and more rarely with single ventricle, transposition of the great arteries and atrioventricular septal defect (1, 7, 9, 11). In addition, extracardiac disorders including omphalocele, gastrochisis, scoliosis, cleft lip-palate and central ne ...
Tachyarrhythmias, Diagnosis and Management
... patients with LV dysfunction and decompensated congestive heart failure to slow ventricular response. • Digoxin alone is rarely effective when the patient is sympathetically driven • Avoid high dose digoxin with amiodarone as digoxin levels increase 2-fold with amiodarone ...
... patients with LV dysfunction and decompensated congestive heart failure to slow ventricular response. • Digoxin alone is rarely effective when the patient is sympathetically driven • Avoid high dose digoxin with amiodarone as digoxin levels increase 2-fold with amiodarone ...
The effect of baroreceptor activity on cardiovascular regulation
... baroreceptors and the second one involves normal variations of AP and the heart rate. The ideal test for the control of baroreceptors must be safe, easy to use, non-invasive, with low failure rates and high repeatability. Unfortunately, all methods used up to date fail in at least one of these param ...
... baroreceptors and the second one involves normal variations of AP and the heart rate. The ideal test for the control of baroreceptors must be safe, easy to use, non-invasive, with low failure rates and high repeatability. Unfortunately, all methods used up to date fail in at least one of these param ...
Heart Valve Mathematical Models - RIT Scholar Works
... flows in the aortic valve region. A Newton-Krylov method was used to estimate periodic solution trajectories, which provide a basis for examining the response to perturbations about initial conditions. Next, an isogeometric model of a heart valve was constructed based on NURBS geometry. The mechanic ...
... flows in the aortic valve region. A Newton-Krylov method was used to estimate periodic solution trajectories, which provide a basis for examining the response to perturbations about initial conditions. Next, an isogeometric model of a heart valve was constructed based on NURBS geometry. The mechanic ...
Echocardiographic Evaluation ofLeft Ventricular Size
... (%AD) and the normalized rate of dimensional shortening (Vd) during isometric and isotonic exercise in normal subjects. In 27 subjects, isometric handgrip exercise at 50% of maximum grip until fatigue produced a significant increase in Ds (33 ± 3.4 (SD) 30.6 i 3.7 mm, p < 0.001), and a reduction in ...
... (%AD) and the normalized rate of dimensional shortening (Vd) during isometric and isotonic exercise in normal subjects. In 27 subjects, isometric handgrip exercise at 50% of maximum grip until fatigue produced a significant increase in Ds (33 ± 3.4 (SD) 30.6 i 3.7 mm, p < 0.001), and a reduction in ...
Editorial
... Because Ito plays a significant role in generating the normal cardiac AP, pharmacological modulations, in addition to naturally occurring modulation, are active topics of research. One example, the experimental drug NS5806, increases peak Ito currents and slows channel inactivation in canine ventric ...
... Because Ito plays a significant role in generating the normal cardiac AP, pharmacological modulations, in addition to naturally occurring modulation, are active topics of research. One example, the experimental drug NS5806, increases peak Ito currents and slows channel inactivation in canine ventric ...
Cardiac Arrhythmias
... feeling of impending doom, facial flushing, hyperventilation, dyspnea, and chest pain. These side effects are often transient owing to the short half-life of adenosine (less than 5 seconds). Prewarning to the patient of these symptoms is helpful. The effects of adenosine are antagonized by caffeine ...
... feeling of impending doom, facial flushing, hyperventilation, dyspnea, and chest pain. These side effects are often transient owing to the short half-life of adenosine (less than 5 seconds). Prewarning to the patient of these symptoms is helpful. The effects of adenosine are antagonized by caffeine ...
Acute management of sudden cardiac death in adults based upon
... Immediate resuscitation The earlier the intervention after the cardiac collapse, the higher the chances of survival. On the basis of the idea that most of the victims of cardiac arrest are initially approached by laypersons, a specific emphasis has been placed, increasing the rate of bystander CPR. S ...
... Immediate resuscitation The earlier the intervention after the cardiac collapse, the higher the chances of survival. On the basis of the idea that most of the victims of cardiac arrest are initially approached by laypersons, a specific emphasis has been placed, increasing the rate of bystander CPR. S ...
Tsuda, T. Pediatric Cardiologist and Associate Professor of
... insidious, and the degree of cyanosis is relatively mild. As these cases are usually not PDA-dependent, PGE1 infusion may not be beneficial unless there is an associated RVOT obstruction. Tricuspid atresia and Ebstein’s anomaly may present with a wide clinical spectrum depending upon the associated ...
... insidious, and the degree of cyanosis is relatively mild. As these cases are usually not PDA-dependent, PGE1 infusion may not be beneficial unless there is an associated RVOT obstruction. Tricuspid atresia and Ebstein’s anomaly may present with a wide clinical spectrum depending upon the associated ...
Atrial thrombus in a premature newborn following cardio
... Comorbidities like inflammation, DIC, fluctuations in cardiac output, congenital heart disease, as well as central venous or arterial catheters, are the predisposing risk factors. Clinically symptomatic or asymptomatic cases are usually picked up by echocardiography, usually done for other indicatio ...
... Comorbidities like inflammation, DIC, fluctuations in cardiac output, congenital heart disease, as well as central venous or arterial catheters, are the predisposing risk factors. Clinically symptomatic or asymptomatic cases are usually picked up by echocardiography, usually done for other indicatio ...
with rheumatic mitral stenosis and normal sinus rhythm - Heart
... included patients with disorders other than rheumatic mitral valve disease. Kranidis et al3 noted similar findings; on the other hand Castello et al4 found that mitral regurgitation was directly related to the presence of spontaDiscussion Our study is the only one of its kind which has neous echo co ...
... included patients with disorders other than rheumatic mitral valve disease. Kranidis et al3 noted similar findings; on the other hand Castello et al4 found that mitral regurgitation was directly related to the presence of spontaDiscussion Our study is the only one of its kind which has neous echo co ...
Congenital heart disease fact sheet
... Sx: effortless incr RR, polycythaemia; presents in neonatal period; causes cyanotic spells; for cyanosis to be present, SaO2 70-80% Ix: hyperoxia test: measure PaO2 15min high flow O2 measure PaO2 should rise by 20mmHg, if not = cyanotic heart disease Epidemiology: 10% of all congenital heart ...
... Sx: effortless incr RR, polycythaemia; presents in neonatal period; causes cyanotic spells; for cyanosis to be present, SaO2 70-80% Ix: hyperoxia test: measure PaO2 15min high flow O2 measure PaO2 should rise by 20mmHg, if not = cyanotic heart disease Epidemiology: 10% of all congenital heart ...
CARDIAC DYSRHYTHMIAS Overview and Therapeutic Modalities
... Knowledge of hemodynamic parameters in the heart is important to understanding disease processes, interventions, and drug treatments. Hemodynamics is the movement of the blood and the forces involved. To understand this concept, you need to know about preload, afterload, and cardiac output. These co ...
... Knowledge of hemodynamic parameters in the heart is important to understanding disease processes, interventions, and drug treatments. Hemodynamics is the movement of the blood and the forces involved. To understand this concept, you need to know about preload, afterload, and cardiac output. These co ...
Recurrence of Left Ventricular Dysfunction in Patients With Restored
... with restored idiopathic DCM is ultrastructural disruption beyond EF representing LV systolic function, it was not confirmed by endomyocardial biopsy or cardiac magnetic resonance imaging (MRI). Although a biochemical examination of endomyocardial biopsy could be used as a research tool, it still ha ...
... with restored idiopathic DCM is ultrastructural disruption beyond EF representing LV systolic function, it was not confirmed by endomyocardial biopsy or cardiac magnetic resonance imaging (MRI). Although a biochemical examination of endomyocardial biopsy could be used as a research tool, it still ha ...
Maximal Exercise Tolerance in Chronic
... of oxygen consumption. In the ischemic group, all of the radionuclide indexes correlated poorly with maximal exercise oxygen consumption (Vo2max) except the peak systolic ejection rate which correlated modestly (r=0.58, p<0.05). Peak systolic ejection rate was significantly lower (p<0.01) as were th ...
... of oxygen consumption. In the ischemic group, all of the radionuclide indexes correlated poorly with maximal exercise oxygen consumption (Vo2max) except the peak systolic ejection rate which correlated modestly (r=0.58, p<0.05). Peak systolic ejection rate was significantly lower (p<0.01) as were th ...
Treatment and management of mitral regurgitation
... LV volumes23 and high systolic pulmonary artery pressure24–26 have also been shown to be correlated with the prognosis, leading to reduced event-free survival. Timing of intervention According to current guidelines,7,8 MV repair is indicated in patients with severe degenerative MR, who are sympto m ...
... LV volumes23 and high systolic pulmonary artery pressure24–26 have also been shown to be correlated with the prognosis, leading to reduced event-free survival. Timing of intervention According to current guidelines,7,8 MV repair is indicated in patients with severe degenerative MR, who are sympto m ...
Prognostic value of electrocardiographic criteria for left ventricular
... predictive of CV mortality. By applying these ECG criteria into routine clinical practice, individuals with LVH who are at higher risk for CV mortality can be identified and appropriately treated. (Am Heart J 2005;150:161- 7.) Left ventricular hypertrophy (LVH) has consistently been shown to be a st ...
... predictive of CV mortality. By applying these ECG criteria into routine clinical practice, individuals with LVH who are at higher risk for CV mortality can be identified and appropriately treated. (Am Heart J 2005;150:161- 7.) Left ventricular hypertrophy (LVH) has consistently been shown to be a st ...
Percutaneous Mitral Valve Therapy: The Next Decade
... market at almost $2 billion by 2014, including only high risk patients not eligible for open heart surgery. The market for percutaneous mitral valve repair or replacement is much more complex, segmenting into different types of disease and different types of treatments. That market is at a very earl ...
... market at almost $2 billion by 2014, including only high risk patients not eligible for open heart surgery. The market for percutaneous mitral valve repair or replacement is much more complex, segmenting into different types of disease and different types of treatments. That market is at a very earl ...
Utility of the surface electrocardiogram for confirming right
... However, evaluation of this criterion for pacing has never been adequately performed. Some studies have used electroanatomical mapping for validating ECG criteria to localize RVOT tachycardia that may serve as a surrogate for RVOT pacing. Dixit et al.12 studied 14 patients using detailed CARTO elect ...
... However, evaluation of this criterion for pacing has never been adequately performed. Some studies have used electroanatomical mapping for validating ECG criteria to localize RVOT tachycardia that may serve as a surrogate for RVOT pacing. Dixit et al.12 studied 14 patients using detailed CARTO elect ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.