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File - IRSC Biology Department
File - IRSC Biology Department

... Anatomy and Physiology II Lab Indian River State College ...
CONGENITAL HEART DEFECTS AND ASSOCIATED GENETIC DISORDERS The
CONGENITAL HEART DEFECTS AND ASSOCIATED GENETIC DISORDERS The

... • Mitral Valve Prolapse – Leaflets are stretched and flop back into the left atrium with each heart beat – blood does not move out effectively • Dilatation of the main pulmonary artery in a patient  40 years old in the absence of valvular, peripheral pulmonic stenosis or other obvious cause • Calci ...
Cardio I
Cardio I

... 4. Describe the two physiological responses that allow oxygen consumption by a tissue or organ to increase when metabolism increases. a. Active tissue will require more oxygen, it achieves this by increasing flow, extraction, or both. b. Physiologically, this means increasing the number of muscle ca ...
VENTRICULAR SEPTAL DEFECT
VENTRICULAR SEPTAL DEFECT

...  Pt.s older than 24mths of age with Qp:Qs is greater than 2:1.  Pt.s with supracristal VSD of any size, because of high risk of development of AI. CONTRAINDICATION –severe pulmonary vascular disease. ...
INTRODUCTION It gives us great pleasure to
INTRODUCTION It gives us great pleasure to

... mortality attributable to sudden cardiac death. Sudden cardiac death is the most common and often the first manifestation of coronary heart disease and occurrence of fatal ventricular fibrillation is associated with ischemic heart, hypertension and hypertrophy as well as diabetic cardiomyopathy. Alt ...
Diagnostic procedures in cardiology
Diagnostic procedures in cardiology

... Chest pain. Characteristics of myocardial ischemia: dull, aching, sensation of pressure or tightness, commonly accompanied by anxiety or uneasiness. Protracted episodes suggest myocardial infarction Location: retrosternal or precordial. (The pain nearly always involves the sternal region.) Radiation ...
Normal Heart NOTES: Normal Heart
Normal Heart NOTES: Normal Heart

... Coarctation of the aorta (COA) refers to narrowing of the aorta. This narrowing may be discrete or long-segment and vary in severity. COA occurs in 8-10% of all congenital heart defects and is often associated with other cardiac lesions such as aortic hypoplasia, abnormalities of the aortic valve, v ...
KS5_Heart_Pupil_Sheets
KS5_Heart_Pupil_Sheets

... ATP and HCM Scientists from Oxford, led by Professor Hugh Watkins, have developed an explanation linking ATP and HCM. Mutations in genes that code for certain cardiac muscle proteins make the muscle contract inefficiently. The contractions need more energy than those in a healthy heart. This means t ...
The Cardiac Cycle Cardiac conduction system Cardiac Muscle
The Cardiac Cycle Cardiac conduction system Cardiac Muscle

... This system, composed of specialized cardiac muscle tissue, initiates and conducts depolarization waves though the myocardium. Impulses from the S-A node pass slowly to the A-V node; impulses travel rapidly along the A-V bundle and Purkinje fibers. ...
Valvular Heart Disease
Valvular Heart Disease

...  Syncope  Tachydysrhythmias causing palpitations  Systolic murmur at apex ...
Blood pressure
Blood pressure

... Vessels branching TPR = 8..l/r4. if vessel of diameter 2 mm branches into two vessels than not to increase periferal resistance the diameter of each has to equals 1.68 mm (NOT for arterioles = resistance) Blood flow – depends on diameter power to 4, ie increase in diameter of 19% increases blood f ...
Document
Document

... • The shorter the PR interval, the louder the first heart sound (mitral valve leaflets are wide open and deep within the ventricle when contraction begins causing the leaflets to close forcefully. • The longer the PR interval, the softer the first sound • The PR interval directly influences the posi ...
Acute management of myocardial infarction
Acute management of myocardial infarction

... • He also smokes 1 pack of cigarettes per day • His past medical history includes hypertension and ...
HEART DISEASE IN PREGNANCY
HEART DISEASE IN PREGNANCY

... Rheumatic valvular lesion predominantly includes mitral stenosis ...
Slide ()
Slide ()

... A. Left ventricular pressure–volume (P–V) loop, the segments of which correspond to events of the cardiac cycle: diastolic ventricular filling along the passive P–V curve (phase I), isovolumetric contraction (phase II), ventricular ejection (phase III), and isovolumetric relaxation (phase IV). B. Th ...
Powerpoint version
Powerpoint version

... Action potential in cardiac muscle These are contractile cells not pacemaker cells Plateau phase ...
Slide ()
Slide ()

... enlargement in left ventricular volume shifts the diastolic pressure-volume curve rightward. Hypertrophy of the ventricle shifts the isovolumic pressureSource: Cardiovascular Disorders: Heart Disease, Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e volume curve leftward (not sho ...
Document
Document

... Mitral Regurgitation ...
Introduction to Fetal Heart Imaging
Introduction to Fetal Heart Imaging

... approximately 45 degrees, cardiac area approximately 1/3 of thoracic area, right ventricle retrosternal, left ventricle-left heart border, foramen ovale protrudes into left atrium, muscles of moderator bands in right ventricle thicker than muscle in left ventricle, tricuspid valve insertion more tow ...
Emergency Medicine CME Quiz
Emergency Medicine CME Quiz

... a. Improved cardiac output by increasing heart rate and improving ventricular diastolic filling time. b. Improved cardiac output by decreasing heart rate and improving ventricular systolic filling time. c. Improved cardiac output by decreasing heart rate and improving ventricular diastolic filling t ...
Cardiac Auscultation
Cardiac Auscultation

... diastole, the heart chambers fill with blood. Ventricular systole causes closure of the mitral and tricuspid valves. Cardiac sounds are named according to the sequence of occurrence and are produced at specific points in the cardiac cycle. The initial heart sound is called the first heart sound or S ...
cardiomyopathies - Canadian Cardiovascular Society
cardiomyopathies - Canadian Cardiovascular Society

... o EF < 35% and worsening NYHA class = ICD should be considered o QRS > 150 ms and NYHA class impaired = CRT to consider - EPS study is not recommended GENETIC TESTING ...
Hypertrophic cardiomyopathy in cats
Hypertrophic cardiomyopathy in cats

... About 12.5% of cats have a heart murmur associated with disease of the heart and the vast majority of these will have some degree of HCM. For many, HCM is almost a variation of normal and they will not experience symptoms from it and only die many years later of another cause. However, in some ...
Heart Disease in Pregnancy
Heart Disease in Pregnancy

... amongst 12,109 deliveries ...
SPM 100 SKILLS LAB 5
SPM 100 SKILLS LAB 5

...  Monitor power  Monitor gain  Change leads ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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