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A. Left ventricular pressure–volume (P–V) loop, the segments of which correspond to events of the cardiac cycle: diastolic ventricular filling along the passive P–V curve (phase I), isovolumetric contraction (phase II), ventricular ejection (phase III), and isovolumetric relaxation (phase IV). B. The ventricle ejects to an end-systolic volume determined by the peak isovolumetric P–V line; an isovolumetric contraction (large arrowheads) from varying end-diastolic volumes (preload). Reproduced with permission from Sperelakis N, Banks RO: Essentials of Physiology. 2nd ed. Boston: Little, Brown and Company; 1996. Source: NORMAL PHYSIOLOGY oF THE CARDIOVASCULAR SYSTEM, Hurst's The Heart, 14e Citation: Fuster V, Harrington RA, Narula J, Eapen ZJ. Hurst's The Heart, 14e; 2017 Available at: http://mhmedical.com/ Accessed: June 11, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved