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Changes in Intracellular pH Associated with Glutamate Excitotoxicity
Changes in Intracellular pH Associated with Glutamate Excitotoxicity

... However, other experiments have questioned the sole involvement of calcium, sinceneuronal death can occur without large deviations in [Ca*+], and high potassium or cyanide induced increasesin [Ca*+], do not produce toxicity (Michaels and Rothman, 1990; Dubinsky and Rothman, 1991). Intracellular acid ...
Ulanovsky et al., 2003
Ulanovsky et al., 2003

... rates (Creutzfeldt et al., 1980; Miller et al., 2002; Yao et al., 2015), and recover more slowly from sensory stimulation (Fitzpatrick et al., 1999), suggesting that forward suppression is, in part, cortically generated. Although it has been argued that forward suppression at the level of the inferi ...
The PLAT domain of LOV-1 interacts with ATP-2 to
The PLAT domain of LOV-1 interacts with ATP-2 to

... for LOV-1 and PKD-2 polycystin function. The C. elegans male uses a series of both chemosensory and mechanosensory behaviors during mating. Male mating is the most complex behavior executed by C. elegans. The male nervous system possesses 381 neurons to the hermaphrodite’s 302 (Sulston et al., 1980; ...
Brain-Derived Neurotrophic Factor Reduces Amyloidogenic
Brain-Derived Neurotrophic Factor Reduces Amyloidogenic

Calcium Binding Protein-Like lmmunoreactivity Labels the Terminal
Calcium Binding Protein-Like lmmunoreactivity Labels the Terminal

... exploiting the spot-metering capability of the photographic system (Nikon UFX-II; Nippon Kogaku) attached to our light microscope (Nikon Optiphot). Specifically, we measured the amount of time required for a constant level of exposure of photographic film having a given sensitivity (we chose ASA 12) ...
Multisensory Integration of Dynamic Faces and Voices
Multisensory Integration of Dynamic Faces and Voices

... regions of the left auditory cortex using standard electrophysiological techniques. We used a custom-made multielectrode drive that allowed us to move up to eight electrodes independently. The minimum interelectrode distance was ⬎2.0 mm. Guide tubes were used to penetrate the overlying tissue growth ...
PDF
PDF

... The vertebrate heart develops from embryonic mesoderm. The process of cardiac development has been studied most extensively in amphibian species. Fate map and embyonic explant studies have identified the location of cardiac precursor cells in several amphibian species. These studies have established ...
Dendritic Signal Integration
Dendritic Signal Integration

... and other proteins can provide important information about the molecular composition and organization of dendrites. Immunolocalization of these molecules can be visualized at the light level, but electron microscopy provides the best way of determining which molecules are expressed in dendrites, as ...
Hippocampus : Neurotransmission and Plasticity in the Nervous
Hippocampus : Neurotransmission and Plasticity in the Nervous

... contains the cell bodies of the pyramidal cells. Based on Golgi impregnation, Lorente de No (1934) divided the CA region into four subfields: CA1, CA2, CA3 and CA4 (figure 2). The CA1 region is adjacent to the subiculum. The CA3 region is adjacent to the fimbria/fornix and choroid plexus. The CA2 re ...
A role for planar cell polarity during early endoderm
A role for planar cell polarity during early endoderm

... knowledge of the morphogenic movements of the endoderm during somitogenesis stages, as it forms a mesenchymal rod, is lacking. Here we characterise endodermal development during somitogenesis stages, and describe the morphogenic movements as the endoderm transitions from a monolayer of cells into a ...
nervous tissue, 030717
nervous tissue, 030717

... Bipolar neurons have one main dendrite and one axon—they are found in some sensory systems including the retina, inner ear, and olfactory area of the brain. ...
Neuronal and microglial cathepsins in aging and age
Neuronal and microglial cathepsins in aging and age

... H. Nakanishi / Ageing Research Reviews 2 (2003) 367–381 ...
The cognitive neuroscience of sustained attention
The cognitive neuroscience of sustained attention

... complex high-level cognitive functions by successively lower neural levels of description benefits from neuroscientific research approaches, and that efforts to determine low-level neuronal mechanisms of cognitive functions benefit from cognitive construct-driven research in humans [25,63,76]. Furth ...
uncorrected proof - Illinois State University Websites
uncorrected proof - Illinois State University Websites

Ectopic Expression of the Neuropeptide Pigment
Ectopic Expression of the Neuropeptide Pigment

... were taken to get all planes of focus of the relevant terminals stained in each brain. These were later mounted in a single picture with the help of Corel PHOTO-PAI N T; then the picture was converted into gray scale. The staining intensity of single pixels was scored in gray scale units on the moun ...
A role for planar cell polarity during early endoderm morphogenesis
A role for planar cell polarity during early endoderm morphogenesis

... knowledge of the morphogenic movements of the endoderm during somitogenesis stages, as it forms a mesenchymal rod, is lacking. Here we characterise endodermal development during somitogenesis stages, and describe the morphogenic movements as the endoderm transitions from a monolayer of cells into a ...
Computation with Spikes in a Winner-Take-All Network
Computation with Spikes in a Winner-Take-All Network

... from the global inhibitory neurons to the array neurons. This configuration allows the fastest spreading of inhibition through the network. With this configuration, we can simplify the network by replacing the global inhibitory interneurons with full inhibitory connectivity between the excitatory neur ...
Molecular and functional analysis of Drosophila single
Molecular and functional analysis of Drosophila single

... a role in controlling axonogenesis of mammillary body axons (Marion et al., 2005). The results from mammals indicate that sim can function in axonogenesis, and this is also a potential role for sim in central brain development given the sim disorganized neuropil phenotype. In this paper, we further ...
Uncovering the Forgotten Effect of Superior Cervical Ganglia on
Uncovering the Forgotten Effect of Superior Cervical Ganglia on

... SAH-induced brain edema, clot formation, displacements and bloody material leakage into the oculomotor nerve roots and basal brain arteries, microembolism in the basilar artery and arachnoid pia adhesions were detected on the macroscopical examinations of the brains in the study group. Basal cistern ...
Impact of prefrontal cortex in nicotine
Impact of prefrontal cortex in nicotine

... (nAChRs) in the PFC to enhance working memory and attention and Bunney, 1983; Ungless et al., 2004), we do acknowledge that there are (Levin, 1992; Granon et al., 1995; Levin et al., 2006; Counotte et al., the technical limitations in the determination of the identities of our 2011; Guillem et al., ...
Human Physiology - Maryville University
Human Physiology - Maryville University

... Temporal Summation Temporal ...
The Medial Frontal Cortex and the Rapid Processing of Monetary
The Medial Frontal Cortex and the Rapid Processing of Monetary

... conditions were “loss-and-error” and “gainand-correct” conditions. By comparing these four conditions, we could test whether the primary cause of the MFN effect was the occurrence of a loss or the occurrence of an error. As Fig. 3 shows, the MFN did not reflect error detection. The primary determina ...
CCNBook/Neuron
CCNBook/Neuron

... -- basically it boils down to whether the model is sufficiently simple to be comprehensible, but not so simple as to make its behavior trivial or otherwise so fully transparent that it doesn't seem to be doing you any good in the first place. One last note on this issue is that the different levels ...
Integration of Sensory and Reward Information
Integration of Sensory and Reward Information

Vol 431 No 7010 pp723-882
Vol 431 No 7010 pp723-882

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Development of the nervous system

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