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Molecular Mechanisms of Signal Integration in Hypothalamic
Molecular Mechanisms of Signal Integration in Hypothalamic

... Stimuli from both internal and external sources can converge on a single neuron which must process these signals and produce an integrated response. Our work is ...
relation between cell size and response characteristics of
relation between cell size and response characteristics of

... the cell body and the axonal diameter of LVN neurons (Deiters, 1865) and physiologic measurements of axonal conduction velocity of LVN neurons activated antidromically from the lumbar cord (Ito et al., 1964; Wilson et al., 1967; Akaike et al., 1973) have confirmed this finding. Finally, these two ne ...
SENSE AND THE SINGLE NEURON: Probing the Physiology of
SENSE AND THE SINGLE NEURON: Probing the Physiology of

... spikes. Three curves are shown in Figure 1B: The leftmost corresponds to the neuron firing at least one spike on a single trial and the other two correspond to the firing of at least two or at least three spikes, respectively. The shapes of these neural detection functions (neurometric functions) ar ...
Visual and Oculomotor Functions of Monkey Subthalamic Nucleus
Visual and Oculomotor Functions of Monkey Subthalamic Nucleus

... saccade volitionally to a visual or remembered target. Presaccadic activity has been shown to occur in caudate neurons and is believed to suppress the tonic spike discharge of SNr neurons, leading to a disinhibition of output neurons in the superior colliculus (Hikosaka et al. 1989a). In addition, c ...
the brainstem control of saccadic eye movements
the brainstem control of saccadic eye movements

... recording method in the late 1960s. Research carried out in the intervening years has made it possible to provide a detailed description of the saccadic command signals that are generated by motor neurons and the formation of these signals in premotor brainstem regions. These findings have been assi ...
Hypothalamus
Hypothalamus

... One of the principal functions of the hypothalamus is to provide temporal organization to the expression of physiological and behavioural processes. This is accomplished by compact cell groups in the rostral hypothalamus, known as the suprachiasmatic nuclei (SCN). SCN neurons exhibit a genetically d ...
Temperature - Division Of Animal Sciences
Temperature - Division Of Animal Sciences

... The Passive System For temperature regulation, the controlled system is the body itself, complete with fully functional cardio-vascular and respiratory systems, metabolic and reproductive activities, and the nervous and endocrine systems controlling these functions. The problem of the passive system ...
Development and function of human cerebral cortex neural networks
Development and function of human cerebral cortex neural networks

... subunits, potentially reflecting the mixture of neurons of different developmental ages present in this system (Shi et al., 2012c). In addition to the major excitatory receptor subunits, we found that subunits of GABA, acetylcholine, dopamine, serotonin, cannabinoid, adrenergic and opioid receptors, ...
Visual Receptive Field Properties of Neurons in the Superficial
Visual Receptive Field Properties of Neurons in the Superficial

PDF
PDF

... feature of cortical dynamics. In recent years, another line of research has attracted great interest: the observation of a bimodal distribution of the membrane potential defining up states and down states at the single cell level (Wilson & Kawaguchi, 1996; Steriade, Contreras, & Amzica, 1994; Contre ...
V1 mechanisms underlying chromatic contrast detection
V1 mechanisms underlying chromatic contrast detection

... (Graham 1977; Sachs et al. 1971). We asked whether signals measured in V1 at a psychophysical detection threshold (PT) are consistent with the cardinal mechanisms model. Although V1 neurons are not tuned to the cardinal color directions when tested with high-contrast stimuli (Horwitz et al. 2007; Jo ...
Different levels of Ih determine distinct temporal integration in
Different levels of Ih determine distinct temporal integration in

Modulation of Neuronal Activity in the Monkey Putamen Associated
Modulation of Neuronal Activity in the Monkey Putamen Associated

... inside the guide and was advanced using a manual hydraulic microdrive (MO95, Narishige, Tokyo, Japan). The signal from neuronal activity was amplified 5,000 times, filtered at 0.3–1.5 kHz, and converted to digital pulses through a window discriminator (NeuroLog, Digitimer, Hertfordshire, UK). Presen ...
The Basal Ganglia
The Basal Ganglia

Basal Ganglia: Internal Organization
Basal Ganglia: Internal Organization

... and in this focal plane gives rise to four primary dendrites. The dendrites are initially spine free and then become densely laden with spines, usually after the first bifurcation. An individual MSN possesses 10 000–15 000 spines, each of which receives a glutamatergic input at its head (see Figure ...
A Double-labeling Investigation of the Afferent Connectivity to
A Double-labeling Investigation of the Afferent Connectivity to

... cortical surface (Van Essen, 1979; Kaas, 1980; Tusa et al., 1981), numerous studies have addressed the question of their afferent connectivity. Anterograde and retrograde tracing techniques have demonstrated extensive redundancy in the connections of these visual areas. In other words, each area rec ...
Cellular scaling rules for the brain of afrotherians
Cellular scaling rules for the brain of afrotherians

... processed. The cerebellum was dissected by cutting the cerebellar peduncles at the surface of the brainstem. The cerebral cortex in all animals was manually dissected from the striatum and other subcortical structures. The hippocampus was then dissected from each cortical hemisphere, under a stereos ...
Gao JCN 2000 - Georgia State University
Gao JCN 2000 - Georgia State University

... 70 sections from the V1 of 53 ferrets, and 67 sections from AI of 55 ferrets (Gao et al., 1999). Immunocytochemistry was used to examine the emergence, distribution, and morphology of PV- and CB-ir neurons in V1 and AI of ferrets. The neuronal morphology and areal and laminar distribution of both PV ...
Clonal analysis of the mushroom bodies
Clonal analysis of the mushroom bodies

... characteristic antigen compositions, Davis and his colleagues proposed that there are three types of neurons with different characteristic axonal projections (Crittenden et al., 1998). One type of neurons (red) project their axons only into the γ lobe, another type of neurons (green) have branched a ...
Central Topography of Cranial Motor Nuclei Controlled by
Central Topography of Cranial Motor Nuclei Controlled by

... trajectories of the migration of facial and accessory abducens neurons were different with adjacent paths radially followed by distinct paths dorsally (Figure 1A) [13]. However, at stage 26 (st26) [14], the migratory streams of both the presumptive facial and accessory abducens nuclei have converged ...
Cortical afferents to the smooth-pursuit region of the macaque
Cortical afferents to the smooth-pursuit region of the macaque

... implanted in one eye. To enhance the accuracy and reproducibility of electrode penetrations and subsequent injections, a plastic grid with 1-mm spacing between adjacent holes (Crist Instrument) was secured inside the recording well. The microelectrodes and injection needles traveled inside 23-gauge ...
MATERNAL BEHAVIOUR IN LACTATING RATS STIMULATES c
MATERNAL BEHAVIOUR IN LACTATING RATS STIMULATES c

... behaviour that included milk letdown. Both groups of dams had a similar number of 67,000 mol. wt glutamate decarboxylaseimmunoreactive cells in each site, although the number of 67,000 mol. wt glutamate decarboxylase-immunoreactive cells per microscopic ®eld was signi®cantly greater in the caudal ve ...
The Stress-Induced Atf3-Gelsolin Cascade Underlies
The Stress-Induced Atf3-Gelsolin Cascade Underlies

Selectivity for the Shape, Size, and Orientation of Objects for
Selectivity for the Shape, Size, and Orientation of Objects for

... di Parma, Istituto di Fisiologia Umana, Plesso Biotecnologico Integrato, 39-I43100 Parma, Italy ...
Cortical cfos Expression Reveals Broad Receptive Field Excitatory
Cortical cfos Expression Reveals Broad Receptive Field Excitatory

... Kim and Ebner, 1999). Overall, it remains unknown whether response heterogeneity in neighboring excitatory neurons is related to differences in the ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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