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MSc Thesis Template Document
MSc Thesis Template Document

... brain’s activity is not yet fully defined and remains a huge research area. This project attempts to approach and understand the diversifications of brain’s responses while interfering with different situations. The aim is to observe and notice brain’s reactions to an external stimulus. Neural activ ...
Neuronal basis of sequential foraging decisions in a
Neuronal basis of sequential foraging decisions in a

Paper - Wharton Marketing
Paper - Wharton Marketing

... Monkeys attempting to maximize local intake rates over the longterm should consider handling time as well as travel time2,3. To confirm that monkeys do so, we performed an additional behavioral experiment in which handling times, but not travel times, were varied from patch to patch (11 sessions, 6 ...
Roles of Multiple Globus Pallidus Territories of Monkeys and
Roles of Multiple Globus Pallidus Territories of Monkeys and

... studies revealed that the anteroventral GP communicates with the medial prefrontal and orbitofrontal cortices, which are involved in motivational control; the anterodorsal GP communicates with the lateral prefrontal cortex, which is involved in cognitive control; and the posterior GP communicates wi ...
PDF
PDF

... murine proNGF on the survival of these neurons cultured at low density at stages throughout late fetal and early postnatal development when these neurons are dependent on a supply of mNGF from their targets for survival. In control cultures (no added factors), the majority of neurons died within 48 ...
A Hebbian learning rule gives rise to mirror neurons and links them
A Hebbian learning rule gives rise to mirror neurons and links them

... and LMAN activity during sensory exposure (Basham et al., 1996; Roberts et al., 2012). We have learned much about the integration of sensory inputs into motor systems from single neuron studies examining responses during motor production and during matched sensory states. Among the key findings are ...
Distribution of neurons in functional areas of the mouse cerebral
Distribution of neurons in functional areas of the mouse cerebral

... used mouse brain atlas, in which the cerebral cortex has been segmented by careful comparison of cytoarchitectonic, connectivity, and functional data (Franklin and Paxinos, 2007). The availability of these cortical subdivision maps, together with the small brain size, makes the mouse cerebral cortex ...
Brain-Derived Neurotrophic Factor Mediates Activity
Brain-Derived Neurotrophic Factor Mediates Activity

... were kept outside the incubator for ⬍1 hr per session. This imaging protocol was found not to cause any apparent ill effects to the imaged neurons or the slice culture, because most neurons remained viable and exhibited the same general dendritic morphology when imaged again 5 or 10 d later (see Fig ...
Nonlinear Population Codes - Department of Nonlinear Dynamics
Nonlinear Population Codes - Department of Nonlinear Dynamics

GABAergic neuron distribution in the pedunculopontine nucleus
GABAergic neuron distribution in the pedunculopontine nucleus

... Indeed, recent studies have shown that there are also functional differences between the two portions of the PPN, which have been evaluated in terms of behavioral responses following excitotoxic lesions or electrical stimulation (Alderson et al., 2006, 2008; Andero et al., 2007). Taken together, the ...
Microstructure of the neocortex: Comparative aspects
Microstructure of the neocortex: Comparative aspects

... The appearance of the neocortex, its expansion, and its differentiation in mammals, represents one of the principal episodes in the evolution of the vertebrate brain. One of the fundamental questions in neuroscience is what is special about the neocortex of humans and how does it differ from that of ...
How Do Neurons Communicate?
How Do Neurons Communicate?

... tell us whether those particular neurons have excitatory or inhibitory effects on other cells. It also helps to tell us something about the behavior in which the neuron is engaged. In the next section, we will look at the structure of a synapse, the site where chemical communication by means of a ne ...
Spontaneous persistent activity in entorhinal cortex modulates
Spontaneous persistent activity in entorhinal cortex modulates

... interactions, whereby MECIII neurons produce a partial decoupling of the CA1 activity from neocortical UDS via their markedly delayed Down transitions and persistent Up states. Notably, the authors found that there was a strong correlation between a neuron’s Down-transition lag and its probability o ...
Kalirin, a Multifunctional Rho Guanine Nucleotide Exchange Factor
Kalirin, a Multifunctional Rho Guanine Nucleotide Exchange Factor

... increase in spine density induced by ephrin B1 was blocked by a Kal-7 mutant lacking GEF activity, by a dominant negative mutant of Rac1, or by a peptide inhibitor of Pak (Penzes et al., 2003). Although these data show that Kalirin can affect process initiation and outgrowth and spine formation, ove ...
Coding Rate and Duration of Vocalizations of the Frog, Xenopus laevis
Coding Rate and Duration of Vocalizations of the Frog, Xenopus laevis

... in 50 ␮M DL-2-amino-5-phosphonopentanoic acid (APV) (SigmaAldrich) in some experiments. To determine whether DTAM neurons expressed NMDARs, we first applied 1 ␮M tetrodotoxin (TTX) (SigmaAldrich) to block all spike-mediated synaptic transmission. The effectiveness of TTX treatment was confirmed when ...
Primitive Roles for Inhibitory Interneurons in Developing Frog Spinal
Primitive Roles for Inhibitory Interneurons in Developing Frog Spinal

... simpler networks in developing lower vertebrates may offer insights into basic organization. To investigate the function of spinal inhibitory interneurons in Xenopus tadpoles, paired whole-cell recordings were used. We show directly that one class of interneuron, with distinctive anatomy, produces g ...
During Arm-Reaching and Isometric-Force Tasks
During Arm-Reaching and Isometric-Force Tasks

... the activity of many M1 neurons was modulated both by the direction in which the arm was pulled by the external forces and by the direction of movement and the static posture of the arm during unloaded arm movements. Furthermore, the directionality of arm movement– dependent and load-dependent respo ...
Neuroethology of reward and decision making
Neuroethology of reward and decision making

... Tobler et al. 2005). Dopamine neurons do not, however, merely signal rewards and the stimuli that predict them. Current evidence suggests that phasic bursts by dopamine neurons may correspond to the reward prediction error term initially proposed in purely behavioural models of learning (Schultz et ...
Increased responses in trigeminocervical nociceptive neurons to cervical input after
Increased responses in trigeminocervical nociceptive neurons to cervical input after

... attributed to a sensitization of central nociceptive neurons with an increased excitability to afferent input. We investigated if noxious dural stimulation evokes sensitization of second-order neurons that leads to an increased responsiveness to stimulation of cervical afferents. Recordings were mad ...
Zwicker Tone Illusion and Noise Reduction in the Auditory System
Zwicker Tone Illusion and Noise Reduction in the Auditory System

... lateral inhibition [13,14] and several types of neurons [15,16]. We list them according to the shape of their receptive field, i.e., their firing rate plotted as a function of a pure tone’s frequency f and intensity I: type I with a V-shaped response domain in the f; I plane, the ‘‘V’’ pointing at ...
The Structure of Spatial Receptive Fields of Neurons in Primary
The Structure of Spatial Receptive Fields of Neurons in Primary

... mapped with multiple stimulus trials was usually confined to approximately one quadrant of VAS. As a rule, VSRFs were very stable over the several hours during which we studied a neuron (Brugge et al., 1994). We applied three metrics to the VSRF (also see Brugge et al., 1996). For each VSRF we compu ...
Dual single unit recording in Globus Pallidus (GP) and Subthalamic
Dual single unit recording in Globus Pallidus (GP) and Subthalamic

... relationship between the two nuclei. A. An in-phase relationship is represented by firing rates that change in the same direction (increase or decrease) in both GP and STN. B An out-ofphase relationship is represented by firing rates that change in the opposite direction in GP and STN. ...
Cation-Chloride Cotransporters and Neuronal Function
Cation-Chloride Cotransporters and Neuronal Function

... GABAA and glycine receptors, CCCs also show close interactions with glutamatergic signaling. A crosstalk among CCCs and trophic factors is important in short-term and long-term modification of neuronal properties. CCCs appear to be multifunctional proteins that are also involved in shaping neuronal ...
Neurofilament and Calcium-Binding Proteins in the
Neurofilament and Calcium-Binding Proteins in the

... 1995a). In particular, gradients of in the density of calbindin-immunoreactive neurons has been reported in the visual cortex of the macaque monkey, where the primary visual areas show much lower densities compared to visual association areas located in the parietal and temporal cortex (Kondo et al. ...
Extracellular Matrix Molecules and Cell Adhesion Molecules Induce
Extracellular Matrix Molecules and Cell Adhesion Molecules Induce

... Proteins, but Stimulates Growth on CAMs Inhibitors of protein kinase C (H7, sphingosine) inhibit CG neuron process outgrowth on LN substrates, and phorbol esters potentiate growth on suboptimal, but not optimal, LN substrates (Bixby, 1989). These results suggest that LN normally activates C kinase i ...
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Mirror neuron

A mirror neuron is a neuron that fires both when an animal acts and when the animal observes the same action performed by another. Thus, the neuron ""mirrors"" the behavior of the other, as though the observer were itself acting. Such neurons have been directly observed in primate species. Birds have been shown to have imitative resonance behaviors and neurological evidence suggests the presence of some form of mirroring system. In humans, brain activity consistent with that of mirror neurons has been found in the premotor cortex, the supplementary motor area, the primary somatosensory cortex and the inferior parietal cortex.The function of the mirror system is a subject of much speculation. Many researchers in cognitive neuroscience and cognitive psychology consider that this system provides the physiological mechanism for the perception/action coupling (see the common coding theory). They argue that mirror neurons may be important for understanding the actions of other people, and for learning new skills by imitation. Some researchers also speculate that mirror systems may simulate observed actions, and thus contribute to theory of mind skills, while others relate mirror neurons to language abilities. Neuroscientists such as Marco Iacoboni (UCLA) have argued that mirror neuron systems in the human brain help us understand the actions and intentions of other people. In a study published in March 2005 Iacoboni and his colleagues reported that mirror neurons could discern if another person who was picking up a cup of tea planned to drink from it or clear it from the table. In addition, Iacoboni has argued that mirror neurons are the neural basis of the human capacity for emotions such as empathy.It has also been proposed that problems with the mirror neuron system may underlie cognitive disorders, particularly autism. However the connection between mirror neuron dysfunction and autism is tentative and it remains to be seen how mirror neurons may be related to many of the important characteristics of autism.Despite the excitement generated by these findings, to date, no widely accepted neural or computational models have been put forward to describe how mirror neuron activity supports cognitive functions such as imitation. There are neuroscientists who caution that the claims being made for the role of mirror neurons are not supported by adequate research.
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