NIH eRA Commons user name: AM2518 TELEPHONE NUMBER
... SYNOPSIS OF PROPOSAL: (use only space provided below; minimum 11 point font) The aim of this translational research project is to develop a novel treatment for patients with medication-resistant OCD, informed by the neurocircuitry, neurochemistry, and neurophysiology of the disorder. There is eviden ...
... SYNOPSIS OF PROPOSAL: (use only space provided below; minimum 11 point font) The aim of this translational research project is to develop a novel treatment for patients with medication-resistant OCD, informed by the neurocircuitry, neurochemistry, and neurophysiology of the disorder. There is eviden ...
Dorsal Column Nuclei Neurons Recorded in a Brain Stem–Spinal
... preparation: characteristics and their responses to dorsal root stimulation. J Neurophysiol 84: 1361–1368, 2000. Recordings were obtained from dorsal column nucleus (DCN) neurons in a neonatal rat brain stem—spinal cord preparation to study their basic electrophysiological properties and responses t ...
... preparation: characteristics and their responses to dorsal root stimulation. J Neurophysiol 84: 1361–1368, 2000. Recordings were obtained from dorsal column nucleus (DCN) neurons in a neonatal rat brain stem—spinal cord preparation to study their basic electrophysiological properties and responses t ...
Electrical membrane properties of rat subthalamic neurons in an in
... chloride ( I E A ) at 10 mM, and blcuculline methiodlde at 50-100 pM. In some animals, the internal capsule, at the level of the entopeduncular nucleus, was transected by a Halazs knife at 6 - 1 0 days prior to the recording. This was tc eliminate afferents to STH ortginating from the structures ros ...
... chloride ( I E A ) at 10 mM, and blcuculline methiodlde at 50-100 pM. In some animals, the internal capsule, at the level of the entopeduncular nucleus, was transected by a Halazs knife at 6 - 1 0 days prior to the recording. This was tc eliminate afferents to STH ortginating from the structures ros ...
Sensory receptors in the anterior uvea of the cat`s eye. An in
... were found in the regional distribution of mean force per stimulus, along with an increase in the latency of thresholds from the pupillary margin to the choroidal the first spike (Fig. 4B). area or in mean threshold of the fibers in the course Mechanical threshold values also were different of the e ...
... were found in the regional distribution of mean force per stimulus, along with an increase in the latency of thresholds from the pupillary margin to the choroidal the first spike (Fig. 4B). area or in mean threshold of the fibers in the course Mechanical threshold values also were different of the e ...
Receptors in lateral hypothalamic area involved in - AJP
... and the cobaltous chloride experiments (11), inhibition of the response was rarely complete. This suggests that the connections between IC autonomic efferents and LHA neurons may be relatively diffusely distributed within this region. This postulation is supported by the anterograde labeling of IC a ...
... and the cobaltous chloride experiments (11), inhibition of the response was rarely complete. This suggests that the connections between IC autonomic efferents and LHA neurons may be relatively diffusely distributed within this region. This postulation is supported by the anterograde labeling of IC a ...
In VivoCalcium Imaging Reveals Functional Rewiring of Single
... Functional mapping and microstimulation studies suggest that recovery after stroke damage can be attributed to surviving brain regions taking on the functional roles of lost tissues. Although this model is well supported by data, it is not clear how activity in single neurons is altered in relation ...
... Functional mapping and microstimulation studies suggest that recovery after stroke damage can be attributed to surviving brain regions taking on the functional roles of lost tissues. Although this model is well supported by data, it is not clear how activity in single neurons is altered in relation ...
Applications of TMS to Therapy in Psychiatry
... resulted in remission in 88% of patients. Although placebo response may have contributed to this effect, it may be that longer treatment is more effective or that patients with melancholic subtype are more responsive to TMS. Of note, the psychomotor symptoms of melancholia predict response to ECT (H ...
... resulted in remission in 88% of patients. Although placebo response may have contributed to this effect, it may be that longer treatment is more effective or that patients with melancholic subtype are more responsive to TMS. Of note, the psychomotor symptoms of melancholia predict response to ECT (H ...
Sensory nerve conduction studies
... Note: With this method it is not possible to measure the conduction velocity across the entrapment site in "meralgia paresthetica". Orthodromic measurement with near nerve electrodes is recommendable in most patients. ...
... Note: With this method it is not possible to measure the conduction velocity across the entrapment site in "meralgia paresthetica". Orthodromic measurement with near nerve electrodes is recommendable in most patients. ...
Neural Coding and Auditory Perception
... responses in reverberation, when compared to model predictions. These results suggest that neural adaptation provides a simple mechanism for improving directional sensitivity in reverberation. In parallel human psychophysical experiments, we found that the range of perceived azimuths is compressed i ...
... responses in reverberation, when compared to model predictions. These results suggest that neural adaptation provides a simple mechanism for improving directional sensitivity in reverberation. In parallel human psychophysical experiments, we found that the range of perceived azimuths is compressed i ...
Part 3 - Health Recovery Group
... Comprehensive Pain Management: Treatment that encompasses both cognitive-behavioral therapy and functional restoration to help people manage chronic-pain problems. Conditioned Responses: Behaviors produced because of past leaming, either through operant or classical conditioning. ...
... Comprehensive Pain Management: Treatment that encompasses both cognitive-behavioral therapy and functional restoration to help people manage chronic-pain problems. Conditioned Responses: Behaviors produced because of past leaming, either through operant or classical conditioning. ...
C ontribution of the anterior cingulate cortex to laser
... of nociceptive stimulation [25]. Furthermore, cingulectomized rabbits fail to learn an inactive avoidance learning that involves avoidance of foot shock [19,20]. The conditioned emotional response is an accepted animal model of emotional stress in which an animal learns to form associations between ...
... of nociceptive stimulation [25]. Furthermore, cingulectomized rabbits fail to learn an inactive avoidance learning that involves avoidance of foot shock [19,20]. The conditioned emotional response is an accepted animal model of emotional stress in which an animal learns to form associations between ...
Studies of the Role of the Paramedian Pontine Reticular Formation
... untrained subjects were used in early experiments, and the range of saccade directions and amplitude generated while the activity of a cell was being studied was not under experimental control. Also, the stability, accuracy, and precision of the methods used to record eye position in these early stu ...
... untrained subjects were used in early experiments, and the range of saccade directions and amplitude generated while the activity of a cell was being studied was not under experimental control. Also, the stability, accuracy, and precision of the methods used to record eye position in these early stu ...
The Superior Olivary Nucleus and Its Influence on Nucleus
... Haer) with tip diameter of 0.5 mm were used for extracellular stimulation. In one experimental configuration, the electrode was placed at the fiber tract from N L and NA to the SON at a distance of 0.5–1 mm away from the SON to study the postsynaptic responses of SON cells. In another experimental c ...
... Haer) with tip diameter of 0.5 mm were used for extracellular stimulation. In one experimental configuration, the electrode was placed at the fiber tract from N L and NA to the SON at a distance of 0.5–1 mm away from the SON to study the postsynaptic responses of SON cells. In another experimental c ...
Novel uses of RadioFrequency ablation
... lasting inhibition of evoked synaptic activity Pulsed RF (PRF) Brief “pulses” of high-voltage RF-range (<300 kHz) electric current voltage fluctuations in the tissue to be treated ...
... lasting inhibition of evoked synaptic activity Pulsed RF (PRF) Brief “pulses” of high-voltage RF-range (<300 kHz) electric current voltage fluctuations in the tissue to be treated ...
Identified Serotonergic Neurons LCBI and RCBI in the Cerebral
... cells to follower cells We next addressed the question of whether stimulating the CBl cells in a manner similar to their response to tail shock produces reliable facilitation of the EPSP from LE sensory cells to follower cells. CBl neurons were identified as described above. An LE sensory cell and a ...
... cells to follower cells We next addressed the question of whether stimulating the CBl cells in a manner similar to their response to tail shock produces reliable facilitation of the EPSP from LE sensory cells to follower cells. CBl neurons were identified as described above. An LE sensory cell and a ...
Historical analysis of the neural control of movement from the
... Whole animal studies then inevitably lapsed, as there must have seemed little that could usefully be done. Acute experimentation reigned throughout the 19th and much of the 20th century as stimulation, ablation, and, subsequently, electrical recording were all within the range of present technology ...
... Whole animal studies then inevitably lapsed, as there must have seemed little that could usefully be done. Acute experimentation reigned throughout the 19th and much of the 20th century as stimulation, ablation, and, subsequently, electrical recording were all within the range of present technology ...
neural projections from nucleus accumbens to globus pallidus
... electrophysiological recordings were made from single neurons in these regions to map the location of units that respond to electrical stimulation of the nucleus accumbens. Recordings also were made from neurons in dorsal parts of the GP (GPd) before the microelectrode was lowered to the GP, and the ...
... electrophysiological recordings were made from single neurons in these regions to map the location of units that respond to electrical stimulation of the nucleus accumbens. Recordings also were made from neurons in dorsal parts of the GP (GPd) before the microelectrode was lowered to the GP, and the ...
Thalamocortical inputs trigger a propagating envelope of gamma
... the thalamocortical pathway in the thinner slices, extracellular deposits of biocytin were made at points between the MG and auditory cortex and the resulting trajectories of projections mapped (Fig. 1C). Biocytin (5% in ACSF) was delivered iontophoretically (100- to 200-nA, 750-ms positive pulse ev ...
... the thalamocortical pathway in the thinner slices, extracellular deposits of biocytin were made at points between the MG and auditory cortex and the resulting trajectories of projections mapped (Fig. 1C). Biocytin (5% in ACSF) was delivered iontophoretically (100- to 200-nA, 750-ms positive pulse ev ...
BETA ACTIVITY: A CARRIER FOR VISUAL ATTENTION
... bands of the EEG have been long studied in clinical research because of their putative functional importance. Old experimental results indicated that repetitive stimulation of the visual pathway evoked synchronous responses at the cortical level with gain depending on frequency: oscillations within ...
... bands of the EEG have been long studied in clinical research because of their putative functional importance. Old experimental results indicated that repetitive stimulation of the visual pathway evoked synchronous responses at the cortical level with gain depending on frequency: oscillations within ...
Neurophysiological investigation of the basis of the fMRI signal
... Active states of any brain site are characterized by time-varying spatial distributions of action potentials superimposed on relatively slow-varying ®eld potentials. An ideal combination is functional imaging in experimental animals with microelectrode recordings of such potentials, including single ...
... Active states of any brain site are characterized by time-varying spatial distributions of action potentials superimposed on relatively slow-varying ®eld potentials. An ideal combination is functional imaging in experimental animals with microelectrode recordings of such potentials, including single ...
Making Mirrors: Premotor Cortex Stimulation
... a movement involving a different muscle. After such training, action observation enhances MEPs from the nonmatching muscle (Catmur, Walsh, & Heyes, 2007). It is not known whether these counter-mirror effects involve the same brain areas that are involved in mirror effects. A demonstration that coun ...
... a movement involving a different muscle. After such training, action observation enhances MEPs from the nonmatching muscle (Catmur, Walsh, & Heyes, 2007). It is not known whether these counter-mirror effects involve the same brain areas that are involved in mirror effects. A demonstration that coun ...
The Preoptic Nucleus in Fishes: A Comparative Discussion of
... strated that PN cells can be activated by wide regions of the telencephalon (Hal\ow\tzet al., 1971). Unfortunately the units recorded were not identified as being en- • docrine neurons by antidromic activation by pituitary stimulation. However, the input from wide regions of the telencephalon does i ...
... strated that PN cells can be activated by wide regions of the telencephalon (Hal\ow\tzet al., 1971). Unfortunately the units recorded were not identified as being en- • docrine neurons by antidromic activation by pituitary stimulation. However, the input from wide regions of the telencephalon does i ...
Nat Methods 6:219-224 - University of British Columbia
... Timothy H Murphy1,2,4 Traditionally, mapping the motor cortex requires electrodes to stimulate the brain and define motor output pathways. Although effective, electrode-based methods are labor-intensive, potentially damaging to the cortex and can have off-target effects. As an alternative method of ...
... Timothy H Murphy1,2,4 Traditionally, mapping the motor cortex requires electrodes to stimulate the brain and define motor output pathways. Although effective, electrode-based methods are labor-intensive, potentially damaging to the cortex and can have off-target effects. As an alternative method of ...
article in press - Neurobiology of Vocal Communication
... Uwe Jürgens ∗ , Steffen R. Hage Department of Neurobiology, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany Received 25 August 2006; received in revised form 15 November 2006; accepted 16 November 2006 ...
... Uwe Jürgens ∗ , Steffen R. Hage Department of Neurobiology, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany Received 25 August 2006; received in revised form 15 November 2006; accepted 16 November 2006 ...
Reinforcement, and Punishment Striatal Mechanisms Underlying
... that drive movement, whereas negative feelings may share common circuitry with cells that inhibit movement. Links between movement, reinforcement, and reward are apparent in many neurological and psychiatric diseases. Depression is commonly described by deficits in reward function, coupled with heig ...
... that drive movement, whereas negative feelings may share common circuitry with cells that inhibit movement. Links between movement, reinforcement, and reward are apparent in many neurological and psychiatric diseases. Depression is commonly described by deficits in reward function, coupled with heig ...