7 Ghrelin signalling
... First there was the receptor, discovered as the binding site of synthetic compounds that caused the immediate secretion of growth hormone (GH) from the somatotrophic cells of the anterior pituitary. These compounds were developed as potential medicaments aiming to restore body growth (by boosting th ...
... First there was the receptor, discovered as the binding site of synthetic compounds that caused the immediate secretion of growth hormone (GH) from the somatotrophic cells of the anterior pituitary. These compounds were developed as potential medicaments aiming to restore body growth (by boosting th ...
5. Third year activities - LIRA-Lab
... and neural sciences. MIRROR has seen the joint effort of a true multidisciplinary team, and we believe that this is not common even in other projects with similar aims. On the other hand, MIRROR did not fully achieve the integration of the many experiments on a single working demonstrator. We would ...
... and neural sciences. MIRROR has seen the joint effort of a true multidisciplinary team, and we believe that this is not common even in other projects with similar aims. On the other hand, MIRROR did not fully achieve the integration of the many experiments on a single working demonstrator. We would ...
Implantable microcoils for intracortical magnetic
... Neural prostheses that can reliably and effectively activate the cortex have the potential to treat a wide range of neurological and psychiatric disorders (1–4). However, effective activation is difficult, given the large diversity of cell types within the cortex coupled with an inability to selecti ...
... Neural prostheses that can reliably and effectively activate the cortex have the potential to treat a wide range of neurological and psychiatric disorders (1–4). However, effective activation is difficult, given the large diversity of cell types within the cortex coupled with an inability to selecti ...
Task-dependent plasticity of spectrotemporal receptive fields in
... 1989), is characterized as modulation of auditory cortical receptive Welds that is (1) behaviorally driven by attentive focus on a salient acoustic feature necessary for task performance, (2) rapid – occurring within minutes of a change in task requirements or acoustics, (3) measured in the awake, b ...
... 1989), is characterized as modulation of auditory cortical receptive Welds that is (1) behaviorally driven by attentive focus on a salient acoustic feature necessary for task performance, (2) rapid – occurring within minutes of a change in task requirements or acoustics, (3) measured in the awake, b ...
working draft - DAVID KAPLAN | Macquarie University
... evidence that computational neuroscientists sometimes employ a distinctive explanatory scheme from that of mechanistic explanation. Because these neural computations can rely on diverse circuits and mechanisms, modeling the underlying mechanisms is supposed to be of limited explanatory value. I argu ...
... evidence that computational neuroscientists sometimes employ a distinctive explanatory scheme from that of mechanistic explanation. Because these neural computations can rely on diverse circuits and mechanisms, modeling the underlying mechanisms is supposed to be of limited explanatory value. I argu ...
Conductance-Based Model of the Voltage
... from, for example, the cortex (Magill et al. 2000). STN neurons, however, have intrinsic membrane properties that can produce more complex firing patterns. In a subset of STN neurons, the generation of a plateau potential, a long-lasting depolarizing potential, have been reported in several studies ...
... from, for example, the cortex (Magill et al. 2000). STN neurons, however, have intrinsic membrane properties that can produce more complex firing patterns. In a subset of STN neurons, the generation of a plateau potential, a long-lasting depolarizing potential, have been reported in several studies ...
The Fine Structure of Slow-Wave Sleep Oscillations: from Single
... at the upper frequency limit of spindling (13–14 Hz) (Fig. 4.3, Ketamine). Under barbiturate anesthesia (25–35 mg/kg), spindling is waxing and waning, and its frequency is lower with increasing barbiturate doses (Fig. 4.3 Barbiturate). During natural slow-wave sleep, two types of spindle patterns we ...
... at the upper frequency limit of spindling (13–14 Hz) (Fig. 4.3, Ketamine). Under barbiturate anesthesia (25–35 mg/kg), spindling is waxing and waning, and its frequency is lower with increasing barbiturate doses (Fig. 4.3 Barbiturate). During natural slow-wave sleep, two types of spindle patterns we ...
6.12 Dorsal and Ventral Streams in the Sense of Touch
... The ventral stream – transmitted through the inferotemporal cortex – is the putative ‘what’ pathway. These cortical areas analyze the visual signals to derive cognitive information about the size, shape, and color of the stimulus. These intrinsic properties allow us to recognize such stimuli as dist ...
... The ventral stream – transmitted through the inferotemporal cortex – is the putative ‘what’ pathway. These cortical areas analyze the visual signals to derive cognitive information about the size, shape, and color of the stimulus. These intrinsic properties allow us to recognize such stimuli as dist ...
Action Potential Backpropagation and Somato
... and Guillery, 1996). A similar anatomical segregation of inhibitory inputs from intrinsic and extrinsic GABAergic neurons may facilitate complex synaptic interactions in the dendrites of TC neurons (Sherman and Guillery, 1996). This synaptic organization highlights the need to directly investigate d ...
... and Guillery, 1996). A similar anatomical segregation of inhibitory inputs from intrinsic and extrinsic GABAergic neurons may facilitate complex synaptic interactions in the dendrites of TC neurons (Sherman and Guillery, 1996). This synaptic organization highlights the need to directly investigate d ...
Chapter 9b final
... fMRI – same regions of the hippocampus were activated during route learning and during SWS the following night Although people who are awakened during SWS seldom report dreaming, sleeping brain rehearses information that was acquired during the previous day Consistent with animal data ...
... fMRI – same regions of the hippocampus were activated during route learning and during SWS the following night Although people who are awakened during SWS seldom report dreaming, sleeping brain rehearses information that was acquired during the previous day Consistent with animal data ...
PDF+Links
... parameter developed by the software) was done at 400 ´ magnification. All consecutive sections of each series were analyzed. The neuronal counts were summarized using the mean neuronal numerical density per unit area analyzed. Thus, data are presented as unmodified neuronal cells counts per region u ...
... parameter developed by the software) was done at 400 ´ magnification. All consecutive sections of each series were analyzed. The neuronal counts were summarized using the mean neuronal numerical density per unit area analyzed. Thus, data are presented as unmodified neuronal cells counts per region u ...
Here - Institute of Cognitive Neuroscience
... provide perhaps the most direct evidence of the nature of the representations at work in spatial cognition. We start with the apparently allocentric representations associated with the mammalian medial temporal lobe. View-invariant hippocampal “place cells” fire selectively for an animal’s location ...
... provide perhaps the most direct evidence of the nature of the representations at work in spatial cognition. We start with the apparently allocentric representations associated with the mammalian medial temporal lobe. View-invariant hippocampal “place cells” fire selectively for an animal’s location ...
PDF
... study behavior from the point of view of its hypothesized function, that is, they study behavior as it should be if it were to accomplish specific goals in an optimal way. The appeal of normative models derives from two primary sources. First, because throughout evolution animal behavior has been sh ...
... study behavior from the point of view of its hypothesized function, that is, they study behavior as it should be if it were to accomplish specific goals in an optimal way. The appeal of normative models derives from two primary sources. First, because throughout evolution animal behavior has been sh ...
Full version (PDF file)
... Zhejiang Province, China. All procedures were approved by the Animal Care and Use Committee of the Institute of Psychology, Chinese Academy of Sciences, and all efforts were made to minimize the rats’ suffering and the number of rats used. NAc slice preparation Rat NAc slices were prepared as follow ...
... Zhejiang Province, China. All procedures were approved by the Animal Care and Use Committee of the Institute of Psychology, Chinese Academy of Sciences, and all efforts were made to minimize the rats’ suffering and the number of rats used. NAc slice preparation Rat NAc slices were prepared as follow ...
Eye Movements - Center for Neural Science
... To understand how muscle forces control the position and movement of the eyes, we must first understand how the tissues and muscles of the orbit produce resistance to movement. In its simplest form, the eye in the orbit can be thought of as a sphere held in place by a system of springs that tend to ...
... To understand how muscle forces control the position and movement of the eyes, we must first understand how the tissues and muscles of the orbit produce resistance to movement. In its simplest form, the eye in the orbit can be thought of as a sphere held in place by a system of springs that tend to ...
Inactivation of Parietal and Prefrontal Cortex Reveals
... of these subpopulations were matched to a greater extent (Chafee and Goldman-Rakic 1998) than could be gleaned from independent studies of the two populations using similar, but not identical, tasks (Andersen et al. 1990b; Bruce and Goldberg 1985; Funahashi et al. 1989 –1991; Gnadt and Andersen 1988 ...
... of these subpopulations were matched to a greater extent (Chafee and Goldman-Rakic 1998) than could be gleaned from independent studies of the two populations using similar, but not identical, tasks (Andersen et al. 1990b; Bruce and Goldberg 1985; Funahashi et al. 1989 –1991; Gnadt and Andersen 1988 ...
Pattern adaptation and cross-orientation interactions in the primary
... allows one to see equally well under a wide range of illumination conditions. A different mechanism of visual adaptation makes its first appearance in the primary visual cortex (V1). The responses of V1 neurons—which are selective for visual attributes such as position, shape, orientation, direction ...
... allows one to see equally well under a wide range of illumination conditions. A different mechanism of visual adaptation makes its first appearance in the primary visual cortex (V1). The responses of V1 neurons—which are selective for visual attributes such as position, shape, orientation, direction ...
elaboration, remodeling and spatial organization of
... The Drosophila olfactory system has gradually become a convenient model system for studying many interesting neurological phenomena, such as odor coding (reviewed by Warr et al., 2001) and conditioned learning (reviewed by Waddell and Quinn, 2001). Formation of olfactory associative memory involves ...
... The Drosophila olfactory system has gradually become a convenient model system for studying many interesting neurological phenomena, such as odor coding (reviewed by Warr et al., 2001) and conditioned learning (reviewed by Waddell and Quinn, 2001). Formation of olfactory associative memory involves ...
First-in-first-out item replacement in a model of
... In the absence of input, the contents of a STM buffer decay gradually, due to noise and a slow-AHP (modeled as a bi-exponential response with Erev = −70 mV, G = 0.01 nS, τrise = τf all = 3000 ms, an alpha function). When a buffer that is filled to capacity receives new input at a rapid pace, so that ...
... In the absence of input, the contents of a STM buffer decay gradually, due to noise and a slow-AHP (modeled as a bi-exponential response with Erev = −70 mV, G = 0.01 nS, τrise = τf all = 3000 ms, an alpha function). When a buffer that is filled to capacity receives new input at a rapid pace, so that ...