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Synaptic plasticity: taming the beast
Synaptic plasticity: taming the beast

... but also acquires stability problems. To avoid excessively high or low firing rates, the total amount of excitatory drive to a neuron or within a network must be tightly regulated, which is difficult to do if synapses are modified independently. What is needed is a mechanism that maintains an approp ...
Nicotinic Acetylcholine Receptor-like Molecules in the Retina
Nicotinic Acetylcholine Receptor-like Molecules in the Retina

... 13. Rinse the sections in Ringer’s for 15 min. 14. Mount the sections in 90% glycerol/lO% Ringer’s. In a few instances immunoperoxidase experiments were performed on only one side of the tectum in order to compare the pattern of staining with the pattern of the retinotectal projection (the retinotec ...
Central mechanisms regulating coordinated cardiovascular and
Central mechanisms regulating coordinated cardiovascular and

... defensive behavioral responses that are accompanied by appropriate autonomic and respiratory changes. As discussed in this review, several brain regions and pathways have major roles in subserving the cardiovascular and respiratory responses to threatening stimuli, which may vary from relatively mil ...
Do cortical areas emerge from a protocottex?
Do cortical areas emerge from a protocottex?

... The set of output projections of a given neocortical area in the adult is a subset of the projections that it originally elaborates. Although just a subset is retained by a given area, these early, widespread projections are made only to specific sets of targets appropriate for the general class of ...
Body Fluids
Body Fluids

... on the one hand, and between blood and the interstitial fluid of the brain, on the other hand. The limited exchange between blood and interstitial fluid of the brain is referred to as the blood–brain barrier. This barrier is permeable to water, oxygen, carbon dioxide, glucose, alcohols, and most ane ...
PREFERENTIAL POTENTIATION OF WEAKER INPUTS TO PRIMARY
PREFERENTIAL POTENTIATION OF WEAKER INPUTS TO PRIMARY

... The magnitude of LTP that can be induced at thalamocortical and intracortical synapses in V1 can be influenced by various neuromodulators. For example, in vitro studies suggest that serotonin lowers the amount of NMDA-dependent LTP that can be obtained in slices of V1 (Edagawa et al., 2001; Kim et a ...
Distinct representations of olfactory information in different cortical
Distinct representations of olfactory information in different cortical

Document
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... The lab’s major area of interest is the CA3 region of the hippocampus. This subregion is where information from two regions outside the hippocampus, the dentate gyrus and the entorhinal cortex, converge. In addition, this area is also characterized by strong recurrent feedback between CA3 pyramidal ...
Supraspinal control of ejaculation
Supraspinal control of ejaculation

... Percentage of galanin cells that were Fos-ir after Home Cage, Anestrous Female, Mounts, M+I, 1 Ejac., 2 Ejacs ...
Understanding the Brain - NSTA Learning Center
Understanding the Brain - NSTA Learning Center

... This web seminar contains information about programs, products, and services offered by third parties, as well as links to third-party websites. The presence of a listing or such information does not constitute an endorsement by NSTA of a particular company or organization, or its programs, products ...
Reflections on `plant neurobiology`
Reflections on `plant neurobiology`

... not to that of auxin (Epel et al., 1992). If nodes interrupt the flow of aqueous solutes, might they not also affect electrical transmission, acting like resistors in an electrical circuit – here, a putative plant-nerve circuit? Resistance to current flow was found in some early electrophysiological ...
Spinal Cord-Evoked Potentials and Muscle Responses Evoked by
Spinal Cord-Evoked Potentials and Muscle Responses Evoked by

... the TA, and the soleus (Sol) (Fig. 1). A ground plate electrode was placed on the shoulder. The impedance of the DC S and muscle recording electrodes was kept ,3 KV. The SCEP and muscle recordings were amplified and displayed using an eight channel C adwell E xcel machine with a sampling rate of 48 ...
Convergence in Mammalian Nucleus of Solitary Tract During
Convergence in Mammalian Nucleus of Solitary Tract During

... responded to tactile stimulation of the tongue with a glass rod were not studied. Because NST gustatory cells usually have low or no spontaneous activity, we searched for taste neurons by stimulating the tongue alternately with NaCl and NH,Cl as the electrode was driven through the medulla. All chem ...
Chapter 9
Chapter 9

... CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
uncorrected proof - Illinois State University Websites
uncorrected proof - Illinois State University Websites

... Email address: http://biology.illinoisstate.edu/avidal, [email protected] (A.G. Vidal-Gadea) http://dx.doi.org/10.1016/j.jphysparis.2016.12.002 0928-4257/© 2016 Published by Elsevier Ltd. ...
Chapter 9- Nervous System Lecture 9.1
Chapter 9- Nervous System Lecture 9.1

... A. Sensory receptors at the ends of peripheral nerves gather information and convert it into nerve impulses. B. When sensory impulses are integrated in the brain as perceptions, this is the integrative function of the nervous system. C. Conscious or subconscious decisions follow, leading to motor fu ...
Slide 1
Slide 1

... • Autonomic Nervous System (ANS) – division of the PNS consisting of nerves that control all of the involuntary muscles, organs, and glands; sensory pathway nerves coming from the sensory organs to the CNS consisting of sensory neurons – sympathetic division (fight-or-flight system): part of the ANS ...
Reinforcement, and Punishment Striatal Mechanisms Underlying
Reinforcement, and Punishment Striatal Mechanisms Underlying

... the two striatal output pathways. The most widely cited expression difference between the two pathways are the dopamine Drd1 receptor, which is selectively expressed by direct pathway neurons, and the dopamine Drd2 receptor, which is selectively expressed by indirect pathway neurons. Due to this dif ...
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PDF

... Marianeli Rodriguez, Jeonghoon Choi, Sungjin Park and Shanthini Sockanathan* SUMMARY The mammalian cortex is a multilaminar structure consisting of specialized layer-specific neurons that form complex circuits throughout the brain and spinal cord. These neurons are generated in a defined sequence di ...
The Spinal Nerve
The Spinal Nerve

... 13-8 The Brain Can Alter Spinal Reflexes Integration and Control of Spinal Reflexes Reflex behaviors are automatic But processing centers in brain can facilitate or inhibit reflex motor patterns based in spinal cord Voluntary Movements and Reflex Motor Patterns Higher centers of brain incorporate l ...
descending projections from the trigeminal ganglion and
descending projections from the trigeminal ganglion and

... TG and MTN neurons have similarities and differences in their neurochemical content. On the one hand, both central and peripheral trigeminal primary afferent neurons express, indeed to a varying degree, classical transmitters. Taken together with the existing neuroanatomical and electrophysiological ...
Eps homology domain endosomal transport proteins differentially
Eps homology domain endosomal transport proteins differentially

... share a central coiled-coil and an N-terminal phosphate binding loop (P-loop) [3,5]. These proteins are products of gene duplication, are encoded on separate chromosomes, and have differential expression profiles in various tissues [3,4,6-8]. In adult tissues, EHD1 is expressed in germ cells, adipoc ...
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PDF file

M100,907, a selective 5-HT antagonist, attenuates dopamine
M100,907, a selective 5-HT antagonist, attenuates dopamine

... receptors regulate DA function in the mPFC. For example, administration of the atypical antipsychotic drug clozapine, a potent 5-HT 2 antagonist [20], increases extracellular DA concentrations in vivo when administered either systemically or directly into the mPFC [15,21,28]. In addition, systemic a ...
Sympathetic nervous system and inflammation: A conceptual view
Sympathetic nervous system and inflammation: A conceptual view

... cord. They send axons from the CNS into the autonomic ganglia and form synapses on the dendrites and cell bodies of the postganglionic neurons. Their axons are myelinated or unmyelinated. Individual sympathetic pre- and postganglionic neurons exhibit spontaneous activity in vivo or are silent. They ...
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Stimulus (physiology)



In physiology, a stimulus (plural stimuli) is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity. When a stimulus is applied to a sensory receptor, it normally elicits or influences a reflex via stimulus transduction. These sensory receptors can receive information from outside the body, as in touch receptors found in the skin or light receptors in the eye, as well as from inside the body, as in chemoreceptors and mechanorceptors. An internal stimulus is often the first component of a homeostatic control system. External stimuli are capable of producing systemic responses throughout the body, as in the fight-or-flight response. In order for a stimulus to be detected with high probability, its level must exceed the absolute threshold; if a signal does reach threshold, the information is transmitted to the central nervous system (CNS), where it is integrated and a decision on how to react is made. Although stimuli commonly cause the body to respond, it is the CNS that finally determines whether a signal causes a reaction or not.
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