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Rhythmicity, randomness and synchrony in climbing fiber signals
Rhythmicity, randomness and synchrony in climbing fiber signals

... spikes recorded from a Purkinje cell with ‘typical rhythmicity’ in an awake rat [13]. A significant peak at 100 ms shows that complex spikes sometimes occur in doublets at an interval of w100 ms. A single complex spike evokes only one or two spikes [38] in a Purkinje cell axon that descends to the c ...
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Copyright 2014 John Wiley & Sons, Inc.
Copyright 2014 John Wiley & Sons, Inc.

... End of Chapter 12 Copyright 2014 John Wiley & Sons, Inc. All rights reserved. Reproduction or translation of this work beyond that permitted in section 117 of the 1976 United States Copyright Act without express permission of the copyright owner is unlawful. Request for further information should b ...
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... source of cholinergic innervation to the telencephalon (Fig. 1.1), was thought to be involved in arousal or sleep regulation. Either lesions or electric stimulation of subregions of the basal forebrain can facilitate sleep and synchronize the EEG, and cholinergic drugs regulate EEG synchrony (33). M ...
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Stimulus (physiology)



In physiology, a stimulus (plural stimuli) is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity. When a stimulus is applied to a sensory receptor, it normally elicits or influences a reflex via stimulus transduction. These sensory receptors can receive information from outside the body, as in touch receptors found in the skin or light receptors in the eye, as well as from inside the body, as in chemoreceptors and mechanorceptors. An internal stimulus is often the first component of a homeostatic control system. External stimuli are capable of producing systemic responses throughout the body, as in the fight-or-flight response. In order for a stimulus to be detected with high probability, its level must exceed the absolute threshold; if a signal does reach threshold, the information is transmitted to the central nervous system (CNS), where it is integrated and a decision on how to react is made. Although stimuli commonly cause the body to respond, it is the CNS that finally determines whether a signal causes a reaction or not.
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