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UNIT II: THE HUMAN BRAIN
UNIT II: THE HUMAN BRAIN

Future of Optogenetics: Potential Clinical Applications?
Future of Optogenetics: Potential Clinical Applications?

... many other functions. For example, in optogenetic study of SCI, genes of ChR2 and halorhodopsin (NpHR) were introduced into the rat spinal cord before injury (Awad et al., 2013). It was expected that the light activation of ChR2 and NpHR expressing animals increase or inhibit activity of the bladder ...
Chapter 12 - FacultyWeb
Chapter 12 - FacultyWeb

... Both require a rapid succession of stimuli at a single synapse. Both are methods by which individual EPSPs combine to result in an action potential. Both occur when simultaneous stimuli are applied at different locations, causing a cumulative effect on transmembrane potential. All of these are corre ...
Sensory Organs and Processes, Part II
Sensory Organs and Processes, Part II

... Inactive rhodopsin ...
The Neural Control of Behavior
The Neural Control of Behavior

Neural Development - Peoria Public Schools
Neural Development - Peoria Public Schools

... • Nerve cells migrate to their final position with amoeba like movement a. Once in their final position, mature neurons do not normally move. ...
Cytology
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...  The CNS does not regenerate while the PNS does  This is NOT due to differences in central and peripheral neurons but due to differences in their glia  CNS oligodendrocytes actively suppress regeneration ...
Slide ()
Slide ()

... Neural networks in relay nuclei integrate sensory information from multiple receptors. A. Sensory information is transmitted in the central nervous system through hierarchical processing networks. A stimulus to the skin is registered by a large group of postsynaptic neurons in relay nuclei in the br ...
Slide ()
Slide ()

The human brain
The human brain

... Defined the cerebral cortex into 52 distinct regions on the basis of their cytoarchitectonic characteristics. ...
Alain Destexhe How much stochastic is neuronal activity ?
Alain Destexhe How much stochastic is neuronal activity ?

... ...
Mind, Brain & Behavior
Mind, Brain & Behavior

... All parts of the cell are made up of protein molecules of different kinds. ...
eating spaghetti!
eating spaghetti!

... nerve impulse in the second neuron. The electrical signal is changing from positive to negative, and it moves the nerve impulse along a neuron. Neurons are in a fiber-like bundle called a nerve, and the impulses are all traveling in the same direction. ...
Effect of Outer Hair Cells on Tuning Curves
Effect of Outer Hair Cells on Tuning Curves

... waves elicit maximal responses at the basal end of the membrane, near the stapes, whereas lowfrequency sounds induce maxima at the other end, near the apex of the cochlea. The membrane has been "uncoiled" in this illustration to show the sensory hair cells, each studded with stiff rods called stereo ...
Nervous System - Crossword Labs
Nervous System - Crossword Labs

... 1. Cells that send and receive signals 2. fight or flight section of the autonomic nervous system 4. Nerves that connect directly to the brain 5. Open in presence of specific chemicals (e.g., ACh) at a binding site 8. Carries sensory information 9. Nerves that connect to the spinal cord 10. Consists ...
Silencing brain cells with
Silencing brain cells with

... chronic pain, epilepsy, brain injury, and Parkinson’s disease. The tools work on the principle that such disorders might be best treated by silencing, rather than stimulating, brain activity. These “super silencers” exert exquisite control over the timing of the shutdown of overactive neural circuit ...
THE NEuRoN - Big Picture
THE NEuRoN - Big Picture

... the opening of channels that allow ions (charged atoms) to flow into the cell from outside. This causes more channels farther along the axon to open, creating a voltage pulse that propagates along it (see arrow). ...
The Nervous System
The Nervous System

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Ch. 12 Nervous Tissue
Ch. 12 Nervous Tissue

... Action Potentials • Transient, large changes in membrane potential – Potential will typically reverse within the cell • Inside becomes positive ...
Essential Cell Biology
Essential Cell Biology

PPT - Wolfweb Websites
PPT - Wolfweb Websites

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A new method to generate neurons effectively from cultured SH
A new method to generate neurons effectively from cultured SH

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Chapter 3
Chapter 3

... 1. Know the main structures of neurons and the structural differences among neurons. 2. Know the main types of glia and their functions. 3. Be able to describe the advantages and disadvantages of the blood-brain barrier. Module 2.2 The Nerve Impulse 4. Understand why the neuron uses considerable ene ...
Data Structures CSCI 262, Spring 2002 Lecture 2 Classes
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... •Photoreceptors sense light through phototransduction. •They are located at the back of the eye, next to the pigment cells which prevent light scattering and are involved in metabolic maintenance of the photoreceptors. •Two major types: •Rods: Rod shaped, very sensitive to light, low acuity, slow te ...
CELL COMMUNICATION
CELL COMMUNICATION

... EQ: Why do cells in multicellular organisms become specialized? ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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