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Segmentation of neuronal nuclei based on clump splitting
Segmentation of neuronal nuclei based on clump splitting

... image noise has been reduced to a minimum in the post-binarization images, nuclei are still difficult to segment, as they may overlap with other nuclei and these nuclei may belong to different cell types (i.e., neurons, astrocytes, oligodendrocytes, pericytes, etc.). To overcome these problems, we ha ...
Self-organization and interareal networks™in™the™primate cortex
Self-organization and interareal networks™in™the™primate cortex

Multiple hypothalamic circuits sense and regulate glucose levels
Multiple hypothalamic circuits sense and regulate glucose levels

... appear to be the opposite of those of orexin/hypocretin cells. In mice, knockout of MCH increases energy expenditure and reduces body weight (88), and these characteristics are also seen in animals lacking the MCH receptor -1 (MCH1R) (57). Central injection of MCH in rats increases the quantities of ...
Recombinant AAV-mediated gene delivery to the central nervous
Recombinant AAV-mediated gene delivery to the central nervous

... injury [63]. Although the brain is a relatively immune privileged site, strong immune and inflammatory responses after intracerebral injection of some viral vectors have been reported [64,65]. In contrast, no cellular immune response to capsid proteins or transgene product has been described followi ...
Excitatory Cerebellar Nucleocortical Circuit Provides Internal
Excitatory Cerebellar Nucleocortical Circuit Provides Internal

... values > 0.31; Table S2). In addition, the electrophysiological properties of the nucleocortical cells were indistinguishable from the IpN neurons without any detectable projection to the cerebellar cortex (Table S2). Next, we characterized the electrophysiological properties of nucleocortical neuro ...
The Distribution of Chandelier Cell Axon Terminals that Express the
The Distribution of Chandelier Cell Axon Terminals that Express the

Optimal decision making theories - Bristol CS
Optimal decision making theories - Bristol CS

The role of temporal parameters in a thalamocortical model of analogy
The role of temporal parameters in a thalamocortical model of analogy

... Fig. 3 shows a detailed activation sequence of this mechanism. The example shows a case where only one of the thalamocortical loops (Loop1) received sensory input, thus, demonstrating how purely cortex-driven activity can be promoted. The cortical feedback to the thalamus that survives the filtering ...
Neural Correlates of Executive Control in the Avian Brain
Neural Correlates of Executive Control in the Avian Brain

... memory that which is relevant, while restricting access to memory or discarding from memory that which is not. Our data are the first example of neural correlates of executive control in a nonmammalian species. We would also argue that they are the most straightforward example of neural correlates of ...
GAP-43 Expression in Primary Sensory Neurons following Central
GAP-43 Expression in Primary Sensory Neurons following Central

... 0 1994 Society for Neuroscience 0270-6474/94/144375-10$05.00/O ...
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PDF

... We addressed these questions by injecting the retrograde tracer Fast Blue (FB) or Diamidino Yellow (DiY) into the SOC and analyzing the distribution of retrogradely labeled cells over broad regions of temporal cortex. FB and DiY are fluorescent tracers that are commonly employed in tract-tracing stu ...
A Synapse Plasticity Model for Conceptual Drift Problems Ashwin Ram ()
A Synapse Plasticity Model for Conceptual Drift Problems Ashwin Ram ()

... computational model? First, conductance of action potentials varies from region to region in the brain. At the neuron level, electrical properties vary from dendrite to dendrite, creating latencies in action potential propagation. However, the processes governing potentiation of synapses should be c ...
The Neurology of Posture
The Neurology of Posture

... summation of the effect called, no surprise, “temporal summation”. Or if another chemical were to change (prolong) the degradation in the secondary cell, it would have the same effect. ...
Tutorial on Pattern Classification in Cell Recording
Tutorial on Pattern Classification in Cell Recording

... or plasticity over the course of the recordings, and so on). These time-dependent trends could subsequently be confounded with the questions of interest in the absence of good trial randomization. Eliminating neurons that appear to have nonstationary responses can lead to improvements in decoding ac ...
Pituitary handout
Pituitary handout

... termed ‘prolactinomas’; causes galactorrhoea, infertility and impotence. Drugs that are dopamine agonists e.g. bromocryptine are used to suppress PRL release from tumours and are also used to suppress lactation in women. Growth hormone = GH or somatotrophin. Secreted by somatotroph cells. ...
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Preview Sample 1

... 49. Drug X passes through the blood-brain barrier via active transport. What does this mean? a. Drug X diffuses through the blood-brain barrier. b. Drug X uses osmosis to pass through the blood-brain barrier. c. Drug X directly attaches to neurons to pass through the blood-brain barrier. d. Drug X u ...
On the Biological Plausibility of Grandmother Cells
On the Biological Plausibility of Grandmother Cells

... columns code for line segments that vary by approximately 10° in rotation). These columns are in turn organized into hypercolumns, such that all simple cells within a given hypercolumn code for lines at the same retinal location (albeit varying in orientation preference), with adjacent hypercolumns ...
Schwann cells
Schwann cells

... A. Neurons - electrical signals to transmit information 1. basic structural unit of the nervous system 2. can send an “action potential” (nerve impulse) down its axon 3. Longevity - can live and function for a lifetime 4. amitotic - fetal neurons lose their ability to undergo mitosis; neural stem ce ...
Synaptic function: Dendritic democracy
Synaptic function: Dendritic democracy

PPT - Altogen Biosystems
PPT - Altogen Biosystems

... Altogen Biosystems offers the A431 Transfection Reagent among a host of 100+ cell line specific In Vitro Transfection Kits. A431 Transfection Reagent is an advanced formulation of a cationic lipid-based reagent, and it is developed to provide high transfection efficiency with A431 and other skin can ...
Behavioral Detectability of Single-Cell Stimulation in the Ventral
Behavioral Detectability of Single-Cell Stimulation in the Ventral

... Key words: thalamus; microstimulation; reverse physiology; single-neuron stimulation; perception; sensation ...
22. ANS.Neuroscience
22. ANS.Neuroscience

... fibers from sympathetic chain by a gray ramus • The sympathetic chains carry the preganglionic fibers from T1-L2 levels up to the head and neck and down into the lower abdomen and pelvis. ...
ANS notes filled
ANS notes filled

... flow to the CNS and muscles. This causes an increase blood flow to some visceral organs, such as the intestines and the kidneys. ...
ANS.Neuroscience.09
ANS.Neuroscience.09

... fibers from sympathetic chain by a gray ramus • The sympathetic chains carry the preganglionic fibers from T1-L2 levels up to the head and neck and down into the lower abdomen and pelvis. ...
c-Jun Expression in Adult Rat Dorsal Root
c-Jun Expression in Adult Rat Dorsal Root

... large diameter DRG neurons. This increased expression was observed for at least 7 days after the lesion and is consistent with the observations of others (24, 25, 43). The absence of c-Jun immunostaining in a small population of DRG neurons after this peripheral ...
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Channelrhodopsin



Channelrhodopsins are a subfamily of retinylidene proteins (rhodopsins) that function as light-gated ion channels. They serve as sensory photoreceptors in unicellular green algae, controlling phototaxis: movement in response to light. Expressed in cells of other organisms, they enable light to control electrical excitability, intracellular acidity, calcium influx, and other cellular processes. Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants have been cloned from other algal species, and more are expected.
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