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Neurobiology of Behaviour
Neurobiology of Behaviour

... An animals response to the environment will be influenced by their underlying nervous system ...
Synaptic and extrasynaptic traces of long-term memory
Synaptic and extrasynaptic traces of long-term memory

... However, it is now also clear that the synapses are not permanent; in fact, synaptic patterns undergo significant change in a matter of hours. This means that to implement the long survival of distant memories (for several decades in humans), the brain must possess a molecular backup mechanism in so ...
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... right and left striate cortex in Fig. 2). He tentatively proposed that the centrencephalic system might represent the highest level of cerebral activity. There are also suggestions that it functions principally in the control of sensory input (e.g., 2, 3, 7), thus relating it to attentive mechanisms ...
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... 2. In the somatic nervous system, the cell bodies of the neurons are in the spinal cord and their axons extend to the skeletal muscles they innervate. 3. The ANS consists of a two-neuron chain in which the cell body of the first neuron, the preganglionic neuron, resides in the spinal cord, and syna ...
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... It is likely that the solution to the problem of distortion invariance will have to be based On local feature types, that is. cells which are sensitive to patterns in only a small subregion of retina. This is implemented in a biologically realistic way by Gabor functions (Gabor. 1946). On the other ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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