Medication Assisted Treatment for Opioid Addiction
... Decrease in high risk behaviors Opportunity to address other factors-mental health, social supports, basic needs ...
... Decrease in high risk behaviors Opportunity to address other factors-mental health, social supports, basic needs ...
Chem 491 presentation
... inhalation: instant peak effects lasting 5-10 min residual effects 30-60 min ...
... inhalation: instant peak effects lasting 5-10 min residual effects 30-60 min ...
1 The Neuromuscular Junction: Pharmacology
... anaesthesia. These derivatives include pancuronium and atracurium. In addition, allosteric (conformational) changes in ACh receptors, or steric hindrance to ACh binding, reduce the affinity of receptors for ACh and therefore its effects. These non-competitive antagonists include phencyclidine (PCP, ...
... anaesthesia. These derivatives include pancuronium and atracurium. In addition, allosteric (conformational) changes in ACh receptors, or steric hindrance to ACh binding, reduce the affinity of receptors for ACh and therefore its effects. These non-competitive antagonists include phencyclidine (PCP, ...
CNS Depressants and Antidepressants
... intensify the action of GABA- very safe, even in overdose ...
... intensify the action of GABA- very safe, even in overdose ...
![Chapter 5 Over the counter drugs[1].](http://s1.studyres.com/store/data/010743665_1-d2aa6b8894f079cb577688845957c18b-300x300.png)
Chapter 5 Over the counter drugs[1].
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
... 1. Liquorice or plant extract: They are irritants of the gastric mucosa and they stimulate the afferent fibers of the vagus nerve to the medulla. This results in increased parasympathetic stimulation of the efferent fiber of the vagus nerve back to the stomach. Vagal stimulation to the lungs increa ...
PHARMACOTHERAPEUTICS -study of rational use of drugs in the
... Alternative controllers in bronchial asthma Recent recommendation : Px should be removed from LABAs due to inc. hospitalizations and death (but ok pa din for COPD) c. Other uses: Adjuncts in the Mx of hyperkalemia (to make K go into cell) Terbutaline - Mx of symptomatic bradycardia (has more sig ...
... Alternative controllers in bronchial asthma Recent recommendation : Px should be removed from LABAs due to inc. hospitalizations and death (but ok pa din for COPD) c. Other uses: Adjuncts in the Mx of hyperkalemia (to make K go into cell) Terbutaline - Mx of symptomatic bradycardia (has more sig ...
Psychopharmacology Training
... Don’t necessarily work better, but are safer and have a less (different) SE profile Subtle differences between compounds: T 1/2 , potency for reuptake inhibition and affinity for some other receptors Overall, less effects on adrenergic, histaminergic and cholinergic ...
... Don’t necessarily work better, but are safer and have a less (different) SE profile Subtle differences between compounds: T 1/2 , potency for reuptake inhibition and affinity for some other receptors Overall, less effects on adrenergic, histaminergic and cholinergic ...
Brief Receptor Theory
... – the relative maximal response caused by a drug in a tissue preparation. A full agonist causes a maximal effect equal to that of the endogenous ligand (or sometimes another reference compound if the endogenous ligand is not known); a partial agonist causes less than a maximal response. – Intrinsic ...
... – the relative maximal response caused by a drug in a tissue preparation. A full agonist causes a maximal effect equal to that of the endogenous ligand (or sometimes another reference compound if the endogenous ligand is not known); a partial agonist causes less than a maximal response. – Intrinsic ...
351 Pharmacology PNS 5th Lecture F
... Thus, the effects of a depolarizing neuromuscular blocking agent move from a continuous depolarization (phase I) to a gradual repolarization (as the sodium channel closes) with resistance to depolarization (phase II) Succinylcholine (suxamethonium) is a prototype for this class of drug. It has a ...
... Thus, the effects of a depolarizing neuromuscular blocking agent move from a continuous depolarization (phase I) to a gradual repolarization (as the sodium channel closes) with resistance to depolarization (phase II) Succinylcholine (suxamethonium) is a prototype for this class of drug. It has a ...
Opioid Pharmacology
... drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist. ...
... drug class specific withdrawal syndrome that can be produced by abrupt cessation, rapid dose reduction, decreasing blood level of the drug, and/or administration of an antagonist. ...
GABA-A receptor subtypes in the brain: a paradigm for CNS drug
... Role of α1, α2 and α3-containing GABA-A receptors The use of molecular biological techniques revealed that a single amino acid was responsible for this profound difference in affinity. The presence of a histidine residue at position 101 of the primary amino acid sequence of the α subunit (numbering ...
... Role of α1, α2 and α3-containing GABA-A receptors The use of molecular biological techniques revealed that a single amino acid was responsible for this profound difference in affinity. The presence of a histidine residue at position 101 of the primary amino acid sequence of the α subunit (numbering ...
schizophrenia
... 56% of patients in a survey admitted to extended periods of time when they are off medication and 32% of those patients cited side effects of their medication as the primary reason. ...
... 56% of patients in a survey admitted to extended periods of time when they are off medication and 32% of those patients cited side effects of their medication as the primary reason. ...
Drugs Affecting the Autonomic Nervous System
... 1. Treatment of chronic bronchospasm (longer duration and minimum cardiac stimulatory effects) 2. In premature labour to reduce uterine contraction ...
... 1. Treatment of chronic bronchospasm (longer duration and minimum cardiac stimulatory effects) 2. In premature labour to reduce uterine contraction ...
Benzodiazepines
... CNS receptors occupancy 20 % – anxiolysis, anticonvulsant 30 % sedation 50 to 70 % hypnosis 95 % - deep anesthesia Differing actions - Other than the other receptor theory ...
... CNS receptors occupancy 20 % – anxiolysis, anticonvulsant 30 % sedation 50 to 70 % hypnosis 95 % - deep anesthesia Differing actions - Other than the other receptor theory ...
PowerPoint
... or a step down drug from methadone for the detoxification and maintenance of opioid users. ...
... or a step down drug from methadone for the detoxification and maintenance of opioid users. ...
1-Nicotinic receptors
... From the name we conclude that these are drugs that mimic the action of Acetylcholine, either by directly binding to a receptor or by increasing the amount of acetylcholine. They have the same structure as the Ach but with some modifications for example, substituting one hydrogen molecule on the ach ...
... From the name we conclude that these are drugs that mimic the action of Acetylcholine, either by directly binding to a receptor or by increasing the amount of acetylcholine. They have the same structure as the Ach but with some modifications for example, substituting one hydrogen molecule on the ach ...
20.b) SYMPATHETIC NERVOUS SYSTEM, ALFA AND BETA
... Excessive sympathomimetic activity. Nausea, vomiting, tachycardia, anginal pain, arrhythmias, headache, hypertension, and peripheral vasoconstriction may be encountered during dopamine infusion. Dopamine is rapidly metabolized to homovanilic acid, and its adverse effects are therefore short-lived. E ...
... Excessive sympathomimetic activity. Nausea, vomiting, tachycardia, anginal pain, arrhythmias, headache, hypertension, and peripheral vasoconstriction may be encountered during dopamine infusion. Dopamine is rapidly metabolized to homovanilic acid, and its adverse effects are therefore short-lived. E ...
Respiratory drugs - Suny-perfusion
... • This is available via SVN, MDI (HFA) • It is also found in a nasal spray (Nasalcrom) for the prophylactic treatment of seasonal and nonseasonal allergic ...
... • This is available via SVN, MDI (HFA) • It is also found in a nasal spray (Nasalcrom) for the prophylactic treatment of seasonal and nonseasonal allergic ...
Serotonergic Modulation of Inspiratory Hypoglossal Motoneurons in
... decrease in peak Fn. In some neurons with relatively low Fcon, the maximum effect could not be determined because it was below the discharge threshold. In these neurons, picoejection was stopped before neuronal activity was completely silenced because the presence of neuronal activity is a prerequis ...
... decrease in peak Fn. In some neurons with relatively low Fcon, the maximum effect could not be determined because it was below the discharge threshold. In these neurons, picoejection was stopped before neuronal activity was completely silenced because the presence of neuronal activity is a prerequis ...
Molecular and Pharmacological Review of Cannabimimetics factsheet
... A central physiological action is determined by the ability of an agent to reach the brain receptors21. The blood–brain barrier hinders many hydrophilic agents to enter the brain. Compounds having a high lipophility rapidly cross the blood–brain barrier. The lipophility of compounds can be specified ...
... A central physiological action is determined by the ability of an agent to reach the brain receptors21. The blood–brain barrier hinders many hydrophilic agents to enter the brain. Compounds having a high lipophility rapidly cross the blood–brain barrier. The lipophility of compounds can be specified ...
1. ------IND- 2016 0643 HU- EN- ------ 20161215 --- --
... the consumer perceive bizarre phenomena as if they were having an out-of-body experience while even losing control of their behaviour. Doses of over 100 mg inevitably cause dissociative effects; due to these effects, the drug can cause addiction, which can lead to abuse. In Sweden, there were 9 case ...
... the consumer perceive bizarre phenomena as if they were having an out-of-body experience while even losing control of their behaviour. Doses of over 100 mg inevitably cause dissociative effects; due to these effects, the drug can cause addiction, which can lead to abuse. In Sweden, there were 9 case ...
6-作用于神经系统的药物
... im: slow and irregular: im× (2)Elimination: t1/2= 44 ±13 hr, its metabolites are demethyldiazepam (去甲西泮) and oxazepam(奥沙西泮), they have pharmacological activity. Diazepam can be secreted from milk, to inhibit CNS of baby. ...
... im: slow and irregular: im× (2)Elimination: t1/2= 44 ±13 hr, its metabolites are demethyldiazepam (去甲西泮) and oxazepam(奥沙西泮), they have pharmacological activity. Diazepam can be secreted from milk, to inhibit CNS of baby. ...