Neuropharmacology of Aggressive Behavior - E
... A series of published single-case and open trials demonstrated that buspirone, whose action increases the release of serotonin, has ...
... A series of published single-case and open trials demonstrated that buspirone, whose action increases the release of serotonin, has ...
hypnotics and sedatives
... • structurally unrelated to each other and to benzodiazepines • therapeutic efficacy as hypnotics is due to agonist effects on the benzodiazepine site of the GABAA receptor • Compared to benzodiazepines, Z compounds are -less effective as anticonvulsants or muscle relaxants -which may be related to ...
... • structurally unrelated to each other and to benzodiazepines • therapeutic efficacy as hypnotics is due to agonist effects on the benzodiazepine site of the GABAA receptor • Compared to benzodiazepines, Z compounds are -less effective as anticonvulsants or muscle relaxants -which may be related to ...
16 Antidepressants
... mouth, blurred vision, increased heart rate, urinary retention. • Nortriptyline and desipramine generally favored over other TCAs due to less sedation and fewer anticholinergic side effects • Overdose (e.g. suicide attempts) can lead to cardiotoxicity ...
... mouth, blurred vision, increased heart rate, urinary retention. • Nortriptyline and desipramine generally favored over other TCAs due to less sedation and fewer anticholinergic side effects • Overdose (e.g. suicide attempts) can lead to cardiotoxicity ...
Pharmacology Update
... • Adverse effects: severe rash, may lead to Stevens‐Johnson syndrome; cauGon when mixing with valproic acid • Side effects: benign rash, headache, blurred vision, ataxia, dizziness, nausea, faGgue ...
... • Adverse effects: severe rash, may lead to Stevens‐Johnson syndrome; cauGon when mixing with valproic acid • Side effects: benign rash, headache, blurred vision, ataxia, dizziness, nausea, faGgue ...
Alfuzosin用於治療女性case之討論
... • The selective alpha-1 adrenergic blockers have been shown to significantly increase urinary flow rates and decrease outflow obstruction and irritation symptoms, such as frequency, nocturia, urgency, and urge incontinence, associated with BPH. • Alfuzosin is a selective α-1 adrenoceptor antagonist. ...
... • The selective alpha-1 adrenergic blockers have been shown to significantly increase urinary flow rates and decrease outflow obstruction and irritation symptoms, such as frequency, nocturia, urgency, and urge incontinence, associated with BPH. • Alfuzosin is a selective α-1 adrenoceptor antagonist. ...
neuro 2007 - addiction education home
... receptors remain undefined and progress toward understanding their functions had been hampered by the lack of selective ligands with appropriate pharmacokinetic properties. The Group I mGlu receptors, comprising mGlu1 and mGlu5 receptors, are well positioned to regulate and fine-tune neuronal excita ...
... receptors remain undefined and progress toward understanding their functions had been hampered by the lack of selective ligands with appropriate pharmacokinetic properties. The Group I mGlu receptors, comprising mGlu1 and mGlu5 receptors, are well positioned to regulate and fine-tune neuronal excita ...
Alcohol antagonists - MIT OpenCourseWare
... is widely used to prevent chemotherapy-induced nausea and vomiting. Ondansetron is also used to prevent nausea and vomiting caused by other things such as radiation therapy, surgery, and viral gastroenteritis (norovirus and rotavirus, “the stomach bug”). As you would expect, ondansetron functions as ...
... is widely used to prevent chemotherapy-induced nausea and vomiting. Ondansetron is also used to prevent nausea and vomiting caused by other things such as radiation therapy, surgery, and viral gastroenteritis (norovirus and rotavirus, “the stomach bug”). As you would expect, ondansetron functions as ...
Drug Chart Part 1 - Website of Neelay Gandhi
... -i.e. non selective betaagonist (can distinguish b/w ...
... -i.e. non selective betaagonist (can distinguish b/w ...
Pharmacology Study Guide – Test 2
... NARCOTIC ANTAGONIST: NARCAN: used IV for immediate action, blocks mu & kappa receptors; reverses opiod works in mins, used when resp are below 10/R per minute, minimal toxicity CONTRAINDICATIONS: allergy, asthma, RT insufficiency, elevated ICP, pregnancy ...
... NARCOTIC ANTAGONIST: NARCAN: used IV for immediate action, blocks mu & kappa receptors; reverses opiod works in mins, used when resp are below 10/R per minute, minimal toxicity CONTRAINDICATIONS: allergy, asthma, RT insufficiency, elevated ICP, pregnancy ...
Action - جامعة الكوفة
... through calcium channels and triggering of interaction between several proteins associated with the vesicles and the nerve ending membrane. This interaction results in the fusion of the vescular and nerve ending membranes, the opening of a pore to the extracellular space, and the release of the stor ...
... through calcium channels and triggering of interaction between several proteins associated with the vesicles and the nerve ending membrane. This interaction results in the fusion of the vescular and nerve ending membranes, the opening of a pore to the extracellular space, and the release of the stor ...
Article - Centre universitaire de santé McGill
... Despite the growing non-medical consumption of amphetamine (Amph) during adolescence, its long-term neurobiological and behavioural effects have remained largely unexplored. The present research sought to characterize the behavioural profile and electrophysiological properties of midbrain monoaminergi ...
... Despite the growing non-medical consumption of amphetamine (Amph) during adolescence, its long-term neurobiological and behavioural effects have remained largely unexplored. The present research sought to characterize the behavioural profile and electrophysiological properties of midbrain monoaminergi ...
Anti- muscarinic agents
... • · During induction of anesthesia, there may be excessive vagal stimulation, which we want to eliminate. ...
... • · During induction of anesthesia, there may be excessive vagal stimulation, which we want to eliminate. ...
Pharmacology Tutoring for Sedative Hypnotics and Antiemetics
... b. Droperidol c. Metoclopramide d. Dimenhydrinate a. ...
... b. Droperidol c. Metoclopramide d. Dimenhydrinate a. ...
Biosketch - UNC School of Medicine
... a. Kenakin T. (2005) New concepts in drug discovery: collateral efficacy and permissive antagonism.Nat Rev Drug Discov. 4(11):919-27 b. Kenakin T. (2007) Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors. Trends Pharmacol Sci. 28(8):407-15. c. K ...
... a. Kenakin T. (2005) New concepts in drug discovery: collateral efficacy and permissive antagonism.Nat Rev Drug Discov. 4(11):919-27 b. Kenakin T. (2007) Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors. Trends Pharmacol Sci. 28(8):407-15. c. K ...
Cannabinoid receptors
... History of Marijuana Marijuana remains a controversial subject in our society—castigated by many as a gateway to the socalled hard drugs, but praised by others as an unappreciated medical marvel. Marijuana is produced from flowering hemp (Cannabis sativa). Hemp has been a major source of fiber in m ...
... History of Marijuana Marijuana remains a controversial subject in our society—castigated by many as a gateway to the socalled hard drugs, but praised by others as an unappreciated medical marvel. Marijuana is produced from flowering hemp (Cannabis sativa). Hemp has been a major source of fiber in m ...
Week 6 lecture slides
... Naltrexone – The FDA has approved naltrexone (as pills) for alcohol dependence. If a recovering alcoholic takes naltrexone and then slips up and drinks a glass or two of liquor, the naltrexone will block the positive feelings usually induced by alcohol. The alcoholic may then reconsider their action ...
... Naltrexone – The FDA has approved naltrexone (as pills) for alcohol dependence. If a recovering alcoholic takes naltrexone and then slips up and drinks a glass or two of liquor, the naltrexone will block the positive feelings usually induced by alcohol. The alcoholic may then reconsider their action ...
Relationship between the Serotonergic Activity and Reinforcing
... Vanover et al., 1992; Howell and Byrd, 1995). Among amphetamine-like drugs that are not as selective for 5-HT activity, Ritz and Kuhar (1989) reported a negative correlation between potency as a reinforcer and binding affinity at the 5-HT transporter (SERT). The depletion of 5-HT by medial forebrain ...
... Vanover et al., 1992; Howell and Byrd, 1995). Among amphetamine-like drugs that are not as selective for 5-HT activity, Ritz and Kuhar (1989) reported a negative correlation between potency as a reinforcer and binding affinity at the 5-HT transporter (SERT). The depletion of 5-HT by medial forebrain ...
Barbiturate
... rhythm underlying the normal sleep–wake cycle. Ramelteon is indicated for the treatment of insomnia in which falling asleep (increased sleep latency) is the primary complaint. The potential for abuse of ramelteon is believed to be minimal, and no evidence of dependence or withdrawal effects has been ...
... rhythm underlying the normal sleep–wake cycle. Ramelteon is indicated for the treatment of insomnia in which falling asleep (increased sleep latency) is the primary complaint. The potential for abuse of ramelteon is believed to be minimal, and no evidence of dependence or withdrawal effects has been ...
GENERAL ANESTHETICS INHALATION ANESTHETICS
... Prodynorphin: Dynorphin has slight preference for k receptor; may be k endogenous ligand Physical and pharmacological properties: Brief & small biological activity; only pathological activity/injury results in measurable (but small) levels of these compounds Modulation of pain experience not w ...
... Prodynorphin: Dynorphin has slight preference for k receptor; may be k endogenous ligand Physical and pharmacological properties: Brief & small biological activity; only pathological activity/injury results in measurable (but small) levels of these compounds Modulation of pain experience not w ...
Slide 1
... a) tissue specificity due to site-specific release b) local mechanisms for termination of transmitter action** -neuronal recapture via active transport (cocaine), then re-storage or metabolism (MAO inhibitors) -post-junctional metabolism (cholinesterase inhibitors) c) feedback based on synaptic tran ...
... a) tissue specificity due to site-specific release b) local mechanisms for termination of transmitter action** -neuronal recapture via active transport (cocaine), then re-storage or metabolism (MAO inhibitors) -post-junctional metabolism (cholinesterase inhibitors) c) feedback based on synaptic tran ...
Pharmacodynamics - obsidian
... Drugs often work by binding to a “receptor” Receptors are found in the cell membrane, in the cytoplasm, and in the nucleus ...
... Drugs often work by binding to a “receptor” Receptors are found in the cell membrane, in the cytoplasm, and in the nucleus ...