BSA2013_EvidenceBasedGeneFinding_31Slides
... Splicevariants produced by alternative splicing confer resistance (D). Splicevariants produced by cDNAs do not confer resistance (A, B, C). ...
... Splicevariants produced by alternative splicing confer resistance (D). Splicevariants produced by cDNAs do not confer resistance (A, B, C). ...
model - Center for Biological Sequence Analysis
... • Metabolic models, built bottom-up, are being refined with genomic information • Data – Model – Predictions – Data: cycle as a Systems Biology theme ...
... • Metabolic models, built bottom-up, are being refined with genomic information • Data – Model – Predictions – Data: cycle as a Systems Biology theme ...
106 DNA- Proteins
... outside the nucleus of the cell. • Nucleic acids are made up of nucleotides. • There are three important parts to a nucleic acid: – phosphoric acid unit, (H3PO4) – five carbon sugar (e.g. ribose or deoxyribose) – nitrogen containing organic bases (e.g. adenine, A) ...
... outside the nucleus of the cell. • Nucleic acids are made up of nucleotides. • There are three important parts to a nucleic acid: – phosphoric acid unit, (H3PO4) – five carbon sugar (e.g. ribose or deoxyribose) – nitrogen containing organic bases (e.g. adenine, A) ...
Supplementary information
... where g and d denote averages, and the summation runs over the number of cell lines. This procedure creates one data point for each of the 1066 node vectors on the GI50 map and provides a visual mean to identify correlated gene responses according to specific map regions. Each gene correlation map y ...
... where g and d denote averages, and the summation runs over the number of cell lines. This procedure creates one data point for each of the 1066 node vectors on the GI50 map and provides a visual mean to identify correlated gene responses according to specific map regions. Each gene correlation map y ...
03 Biotechnology Note
... can be detected between individuals so in humans, we have the same genes but different alleles but for forensics, scientists actually look at the non-coding regions of DNA which contain variations in the number of tandem repeats by running a DNA analysis in a process similar to gel electrophor ...
... can be detected between individuals so in humans, we have the same genes but different alleles but for forensics, scientists actually look at the non-coding regions of DNA which contain variations in the number of tandem repeats by running a DNA analysis in a process similar to gel electrophor ...
Central Dogma of Molecular Biology
... sequence of amino acids that make up the protein. Instructions for making proteins with the correct sequence of amino acids are encoded in DNA. DNA is found in chromosomes. In eukaryotic cells, chromosomes always remain in the nucleus, but proteins are made at ribosomes in the cytoplasm. How do the ...
... sequence of amino acids that make up the protein. Instructions for making proteins with the correct sequence of amino acids are encoded in DNA. DNA is found in chromosomes. In eukaryotic cells, chromosomes always remain in the nucleus, but proteins are made at ribosomes in the cytoplasm. How do the ...
Document
... Homologues are similar sequences in two different organisms that have been derived from a common ancestor sequence. Homologues can be described as either orthologues or paralogues. Orthologues are similar sequences in two different organisms that have arisen due to a speciation event. Orthologs ...
... Homologues are similar sequences in two different organisms that have been derived from a common ancestor sequence. Homologues can be described as either orthologues or paralogues. Orthologues are similar sequences in two different organisms that have arisen due to a speciation event. Orthologs ...
How are protein products made from a gene?
... Analogy: Steps 1-3 of the diagram can be described in a different way: DNA is like a cookbook, with each recipe being equivalent to a gene. If a recipe is copied down so someone can go to the store and buy the ingredients, this is like making RNA. The ingredients are mixed together, and prior to bei ...
... Analogy: Steps 1-3 of the diagram can be described in a different way: DNA is like a cookbook, with each recipe being equivalent to a gene. If a recipe is copied down so someone can go to the store and buy the ingredients, this is like making RNA. The ingredients are mixed together, and prior to bei ...
Introduction to high-‐throughput experiments and data analysis
... RNA (Ribonucleic acid) • Similar to DNA, but – RNA is usually single-‐stranded. – The base U is used in place of T. – The backbone is different. ...
... RNA (Ribonucleic acid) • Similar to DNA, but – RNA is usually single-‐stranded. – The base U is used in place of T. – The backbone is different. ...
Green Fluorescent Protein (GFP)
... • for 1 gene, only ~1 mutation in 10 million replications • each day, ~2,000 bacteria develop mutation in that gene • but consider all 4300 genes, then: 4300 x 2000 = 9 million mutations per day per human host! ...
... • for 1 gene, only ~1 mutation in 10 million replications • each day, ~2,000 bacteria develop mutation in that gene • but consider all 4300 genes, then: 4300 x 2000 = 9 million mutations per day per human host! ...
DNA - Laboratory of Theory of Biopolymers
... A. Kolinski, J. Skolnick and R. Yaris, "Monte Carlo Studies on the Long Time Dynamic Properties of Dense Cubic Lattice Multichain Systems. I. The Homopolymeric Melt", J. Chem. Phys. 86:71647174 (1987). A. Kolinski, J. Skolnick and R. Yaris, "Monte Carlo Studies on the Long Time Dynamic Properties of ...
... A. Kolinski, J. Skolnick and R. Yaris, "Monte Carlo Studies on the Long Time Dynamic Properties of Dense Cubic Lattice Multichain Systems. I. The Homopolymeric Melt", J. Chem. Phys. 86:71647174 (1987). A. Kolinski, J. Skolnick and R. Yaris, "Monte Carlo Studies on the Long Time Dynamic Properties of ...
Examination in Gene Technology, TFKE38 2011-10-18
... d) To study the protein spectroscopically you want by site-directed mutagenesis to replace Tyr7 to a tryptophan (Tyr7 (Y7 in one-letter code)) selected in the protein sequence in bold and underlined). Design primers for using the QuikChange method to do this amino acid replacement. Give a justificat ...
... d) To study the protein spectroscopically you want by site-directed mutagenesis to replace Tyr7 to a tryptophan (Tyr7 (Y7 in one-letter code)) selected in the protein sequence in bold and underlined). Design primers for using the QuikChange method to do this amino acid replacement. Give a justificat ...
Gene Expression
... • Transcription Factors – bind specifically to gene’s promoters – turn on and off • Methylation – silencing of huge sections of DNA • Acelylation – activating huge sections of DNA • Chromatin and histones – bound will cause a gene to be silenced ...
... • Transcription Factors – bind specifically to gene’s promoters – turn on and off • Methylation – silencing of huge sections of DNA • Acelylation – activating huge sections of DNA • Chromatin and histones – bound will cause a gene to be silenced ...
PCR – polymerace chain reaction
... No harm (for binding) of one or two mismatches Primers can be designed to contain errors Binding is not disturbed SILENT MUTATION: one base is placed by another base, witch won’t change amino acid sequence ...
... No harm (for binding) of one or two mismatches Primers can be designed to contain errors Binding is not disturbed SILENT MUTATION: one base is placed by another base, witch won’t change amino acid sequence ...
Target-triggered DNA three-way junction superstructure and
... Subtyping of influenza is critical for its treatment, diagnosis and surveillance. Due to the emergence of new subtypes and highly pathogenic avian influenza viruses, novel analytical approaches for monitoring their appearance and further facilitating the development of vaccine are in urgent need [1] ...
... Subtyping of influenza is critical for its treatment, diagnosis and surveillance. Due to the emergence of new subtypes and highly pathogenic avian influenza viruses, novel analytical approaches for monitoring their appearance and further facilitating the development of vaccine are in urgent need [1] ...
Transcription
... • Chemical signals turn gene for a specific protein on. • Enzymes attach to DNA at the gene’s location and unzip only where that gene is on the DNA. – DNA A T C G ...
... • Chemical signals turn gene for a specific protein on. • Enzymes attach to DNA at the gene’s location and unzip only where that gene is on the DNA. – DNA A T C G ...