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CSC598BIL675-2016-L1 - Department of Computer Science
CSC598BIL675-2016-L1 - Department of Computer Science

Classification of protein functions
Classification of protein functions

... • Plot the number of changes in amino-acids between the same protein in different species (such as cytochrome C) against the time since the species diverged • Gives a straight line - so evolution of a protein sequence proceeds at a constant rate and therefore can be used as a ...
Automate Function Prediction
Automate Function Prediction

... • Score GO classes using a score that takes the frequency of GO class in seq. DB into account • Method is used to predict: – GO Classes ...
Leishmania major Friedlin chromosome 1 has an unusual
Leishmania major Friedlin chromosome 1 has an unusual

... region upstream of each unit of colinear genes, where transcription initiates and proceeds toward each telomere. Alternatively, transcription may initiate at multiple sites along the chromosome. Indeed in the extreme, initiation may occur somewhat randomly on both strands, resulting in the transcrip ...
Ka/Ks
Ka/Ks

... • Mechanism providing variation (mutations; insertions and deletions; crossing-over; etc.) • Selection: some traits lead to greater fitness of one individual relative to another. Darwin wrote “survival of the fittest” Evolution is a conservative process: the vast majority of mutations will not be se ...
Central Dogma of Biology - Marengo Community Middle School
Central Dogma of Biology - Marengo Community Middle School

... Transcription and translation are the two main processes linking gene to protein: an overview • Genes provide the instructions for making specific proteins. • The bridge between DNA and protein synthesis is RNA. • RNA is chemically similar to DNA, except that it contains ribose as its sugar and sub ...
File
File

... bacteria to another. This is called transformation. ...
Gene Regulation
Gene Regulation

... that would turn on all the genes in a pathway at one time using 2 enhancer sequences and 2 activator proteins but does not turn on more than one pathway at a time?  specific combinations of transcription factors could be used to regulate a group of genes for a given pathway. Using combinations of a ...
Inheritance of Traits
Inheritance of Traits

Class 10 Heredity and Evolution CBSE Solved Test paper-5
Class 10 Heredity and Evolution CBSE Solved Test paper-5

... molecules to combine in the shallow seas and produce various organic molecules such as sugars. Slowly, these organic molecules combined to form big molecules which include proteins and simple RNA and DNA molecules. The enzymes, proteins, RNA and DNA once formed constituted a self-replicating system ...
Molecular Clocks
Molecular Clocks

... • The clock is stochastic: changes happen at ...
Ch. 13 – Biotechnology
Ch. 13 – Biotechnology

... -  electric shock creates temporary pores in membranes Viruses and bacteria -  carry recombinant DNA into cells Transgenic animals Gene guns -  shoot the host cells with particles of DNA ...
Amino Acids - WordPress.com
Amino Acids - WordPress.com

... • mRNA = Copy of gene/DNA (instructions for making the protein) • tRNA = Translates/Decodes mRNA and Transfers/Delivers amino acids to the ribosome in the correct sequence • rRNA = Ribosomes are made of rRNA which Bond amino acids together to build the Polypeptide (protein) ...
DNA,Rep,RNA,Trans pp
DNA,Rep,RNA,Trans pp

... 1. RNA polymerase (an enzyme) separates the DNA by breaking the hydrogen bonds (DNA unzips) 2. RNA polymerase brings in RNA nucleotides to bond with their complimentary bases along one side of the DNA molecule 3. RNA polymerase drops off, mRNA moves away, DNA molecule closes ...
class title - Palomar College
class title - Palomar College

... Repressible and inducible operons; eukaryotic chromosomes; activator and inhibitory proteins; hypercoiling; a detailed look at chromosomal replication; telomeres and causes for ...
infographic - Nestlé Nutrition Institute
infographic - Nestlé Nutrition Institute

CRISPR-Cas Genome Manipulation
CRISPR-Cas Genome Manipulation

... 3. What’s the function of the gene(s) being targeted? 4. What’s the objective in using CRISPR? a. Gene drive b. Gene knockout/indel c. Genome-wide screening d. Activate, enhance or repress expression e. Imaging or purification of gene loci f. Fuse gene with a reporter g. Generate a point mutation 5. ...
DNA Technology
DNA Technology

... that carry out the research need to make a profit to stay in business. This has led to situations where a company may try to take out a patent on a gene – how would you feel if one of your genes legally belonged to someone else? Genetic screening can pinpoint genes that may cause health issues later ...
PPT
PPT

... – Rank based selection ...
August letters to ed - Universität Düsseldorf
August letters to ed - Universität Düsseldorf

Note 7.4 - Controlling Gene Expression
Note 7.4 - Controlling Gene Expression

Unit 4 Checklist of Knowledge File
Unit 4 Checklist of Knowledge File

... 3A: Heritable information provides for continuity of life o 3.A.1: DNA and in some cases, RNA, is the primary source of heritable information ▪ Genetic information is transmitted from one generation to the next through DNA or RNA ▪ DNA and RNA molecules have structural similarities and differences t ...
PCR amplifies any target DNA sequence. (N)
PCR amplifies any target DNA sequence. (N)

... Quantitative PCR (QPCR) defines amount of starting template. ...
DNA Technology
DNA Technology

... ▫ 2. separate fragments of DNA using electrophoresis (separates DNA according to size and charge) ▫ 3. placed in wells made on gel and run electric current through gel ...
Making RNA in other ways
Making RNA in other ways

... • The activity of AZT depends on the ability of an enzyme to mistakenly incorporate it instead of thymidine • Random mutation of reverse transcriptase due to its inherent error rate results in the chance occurrence of an RT that can discriminate between the two nucleotides – The same process works f ...
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Molecular evolution

Molecular evolution is a change in the sequence composition of cellular molecules such as DNA, RNA, and proteins across generations. The field of molecular evolution uses principles of evolutionary biology and population genetics to explain patterns in these changes. Major topics in molecular evolution concern the rates and impacts of single nucleotide changes, neutral evolution vs. natural selection, origins of new genes, the genetic nature of complex traits, the genetic basis of speciation, evolution of development, and ways that evolutionary forces influence genomic and phenotypic changes.
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