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Human Skeletal Muscle Expresses a Glycogen
Human Skeletal Muscle Expresses a Glycogen

... of three BAC genomic clones established that there was only one GL gene within each clone, indicating that GL is encoded by a single gene in the human genome. Expression of GL mRNA and protein in several tissues, including heart and skeletal muscle. Analysis of the tissue distribution of human GL mR ...
Genome sequence of Aspergillus luchuensis
Genome sequence of Aspergillus luchuensis

... koji mold because the a strain possessed biseriate conidial heads, although its morphological characteristics were similar to those of A. luchuensis. These kuro koji molds exhibit clear differences from standard A. niger strains, where the conidial surface is smooth and unable to assimilate nitrate ...
Splicing together sister chromatids
Splicing together sister chromatids

... emoval of introns from mRNA precursors in the cell nucleus (pre-mRNA splicing) is an essential process for the generation of translatable mRNAs. The splicing machinery (also known as the spliceosome) is composed of small nuclear RNAs (snRNAs), and about 150 proteins involved in the recognition and r ...
Exploring Prostate Proteins and Antibodies
Exploring Prostate Proteins and Antibodies

... We have compiled a list of a selected number of antibodies against prostate specific proteins. Explore the links to the Human Protein Atlas in the table below, and see the tissue expression for the respective proteins in various tissues illustrated with RNA FPKM values as well as staining intensity ...
Full Text
Full Text

... function of a new protein or group of related proteins. One such approach has been the use of multiple sequence alignment methods to create families of related proteins (1,2). The conservation information contained in a multiple sequence alignment is often condensed into a sequence motif to provide ...
Folie 1 - FLI
Folie 1 - FLI

... similarities, aligning sequences with structures, modeling of rigid body shifts, distortions, loops and side chains, as well as detecting errors in a model. Despite these problems, it is currently possible to model with useful accuracy significant parts of approximately one third of all known protei ...
Chapter 16 The Molecular Basis of Inheritance
Chapter 16 The Molecular Basis of Inheritance

... • Begin translation translation. before • mRNA has a 5’ transcription is methyl G cap finished. added ...
Avian Infectious Bronchitis Virus (IBV)
Avian Infectious Bronchitis Virus (IBV)

... This product is developed, designed and sold for research purposes only. It is not intended for human diagnostic or drug purposes or to be administered to humans unless clearly expressed for that purpose by the Food and Drug Administration in the USA or the appropriate regulatory authorities in the ...
PDF
PDF

... tive DNA polymerase III ␣-subunit was also identified in T. of DNA replication, including asymmetric distribution of tengcongensis (TTE1398). The presence of two ␣-subunits is not oligomers (Salzberg et al. 1998), GC-skew (G-C/G + C; Lobry exceptional for T. tengcongensis: this function of polC gene ...
PDF - BMC Genomics
PDF - BMC Genomics

... development of a novel profile that can provide suitable information to the algorithm. One of the key features of this profiling technique is the use of multiple structural alignments of remote homologues to create an extended sequence profile and combines the structural information with suitable ch ...
Slide 1
Slide 1

... Claims Permissible in the Labelling and Advertising of Functional Foods • According to the Guidelines for Registration for Functional Foods, the functional (health) food referred to a food that has special health functions or is able to supply vitamins and minerals. It is suitable for consumption b ...
Protein Requirements of Pregnant and Lactating Women
Protein Requirements of Pregnant and Lactating Women

... 10 kg, and that the birth weight of their babies was not different protein requirement ignores the demand that is placed by the from normal-BMI women. Another possible adaptation is the environment, since primary measurements are often made in reduction of protein oxidation through a reduction in ur ...
Document
Document

... base pairing RNA stem-loop ...
Precise Gene Disruption in Saccharomyces cerevisiae by Double Fusion Polymerase Chain Reaction.
Precise Gene Disruption in Saccharomyces cerevisiae by Double Fusion Polymerase Chain Reaction.

... must chose a less than optimal configuration, either leaving some of the reading frame intact or removing flanking sequences that may affect the expression of important neighboring genes. Recently a one-step PCR procedure was described for gene disruption in yeast (Baudin et al., 1993; Wach et a/., ...
Oxytocin Hormone synthesis and regulation in the Body
Oxytocin Hormone synthesis and regulation in the Body

... in
two
forms,
a
4.4‐long
kb
transcript
found
in
the
ovary
and
a
3.6
kb
transcript
in
the
breast
 (Gimpl
and
Fahrenholz,
2001).

This
isomers
results
from
alternative
splicing
of
the
OTR
gene,
in
 which
some
exons
may
be
included
or
excluded
from
the
final
mRNA
product
during
 transcription.
The
enco ...
INPS: predicting the impact of non-synonymous variations on protein
INPS: predicting the impact of non-synonymous variations on protein

... and on different datasets. They address three different questions. Briefly, they can: (i) predict the DDG real values (in regression) upon residue substitution, (ii) predict whether a residue substitution promotes a DDG increase or decrease (two class predictors) and (iii) predict whether a mutation ...
Genomescale models of metabolism and gene expression extend
Genomescale models of metabolism and gene expression extend

... A nutritional environment is then defined by setting constraints on the availability and uptake of nutrients. For a particular nutritional environment, there is a maximum growth rate at which the cell can no longer produce enough RNA and protein machinery to meet the demands of growth. The computed c ...
Functions of Ribosome-Associated Chaperones and their Interaction
Functions of Ribosome-Associated Chaperones and their Interaction

... ability to promote the insertion of chemically denatured pro-OmpA into membrane vesicles [31]. However, TF is not essential for viability of E. coli and deletion of its gene tig does not cause any growth defect albeit the heat shock response is induced leading to enhanced levels of chaperones and pr ...
The Malaria Parasite`s Chloroquine Resistance Transporter is a
The Malaria Parasite`s Chloroquine Resistance Transporter is a

... transporter superfamily (Martin, Trueman, and Kirk 2003; Tran and Saier 2004). Here we present a detailed bioinformatic analysis of the protein and of the family and superfamily to which it belongs. Comparisons between PfCRT and members of the superfamily provide insight into the possible role of th ...
Anabaena - Oxford Academic
Anabaena - Oxford Academic

... chococcus sp. PCC 7942 exhibited similar dark respiratory activity, as measured by oxygen uptake, to that of the wild-type [21]. Thus cyanobacteria may employ an alternative respiratory pathway when the OPP is non-functional. The OPP is also thought to be largely responsible for the supply of reduct ...
The Carboxyl-Terminal Region of Protein C Is
The Carboxyl-Terminal Region of Protein C Is

... (Fig 4e). Mock-transfected CHO cells did not show any specific immunolabelling (Fig 4g and h). From these results, we conclude that the transport of PC407 and PC408 from rough ER to the Golgi apparatus is blocked and that these mutant proteins are retained in the rough ER, whereas PC409 was transpor ...
Genome Sequence of an Extremely Halophilic Archaeon
Genome Sequence of an Extremely Halophilic Archaeon

... they are composed of two components, a major fraction that is G+C-rich and a relatively A+T-rich (58% G+C) satellite (5). Subsequent studies showed that the satellite deoxyribonucleic acid (DNA) corresponded mainly to large heterogeneous extrachromosomal replicons containing many transposable insert ...
Localization of Protein-Protein lnteractions between Subunits of
Localization of Protein-Protein lnteractions between Subunits of

... with a protein that must be a dimer to function, remove that protein's dimerization region, and replace it with segments of a second protein. If one of the segments of the second protein contains a region through which the new chimeric protein is able to properly self-associate, activity will be res ...
Innovative Purification Protocol for Heparin Binding
Innovative Purification Protocol for Heparin Binding

... as rHI, under the trade name Humulin [43, 45]. Since then, different biopharmaceuticals products have been developed like blood factors used for treatment of haemophilia, thrombolytic agents used to treat thromboembolism, hematopoietic growth factors used in the treatment of blood related diseases, ...
copy_of_secstruc
copy_of_secstruc

... GLY: high conformational flexibility => tight turns,… PRO: side-chain bounds back to backbone => tight turns. CYS: disulfide bridges. ...
< 1 ... 65 66 67 68 69 70 71 72 73 ... 524 >

Gene expression



Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.
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