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ppt - Bio 5068
... Analysis of the Quality of NMR Protein Structures With A Structure Calculated From Your NMR Data, How Do You Determine the Accuracy and Quality of the Structure? • Consistency with Known Protein Structural Parameters bond lengths, bond angles, dihedral angles, VDW interactions, etc all the struct ...
... Analysis of the Quality of NMR Protein Structures With A Structure Calculated From Your NMR Data, How Do You Determine the Accuracy and Quality of the Structure? • Consistency with Known Protein Structural Parameters bond lengths, bond angles, dihedral angles, VDW interactions, etc all the struct ...
The 2009 Nobel Prize in Chemistry and KEK`s Photon Factory
... deteriorate, chemical complexity, large size, and ...
... deteriorate, chemical complexity, large size, and ...
... create mixtures consisting of polymers of biotinylated moieties with avidin or streptavidin (3). These polymers could still have some free binding sites for biotin, thus becoming more-sensitive detection reagents in pertinent applications. (d) Biotin is a small molecule (244.31 Da) that, when introd ...
Role of adaptor protein Toll-Like Interleukin domain containing
... DMD Fast Forward. Published on October 15, 2015 as DOI: 10.1124/dmd.115.066761 This article has not been copyedited and formatted. The final version may differ from this version. ...
... DMD Fast Forward. Published on October 15, 2015 as DOI: 10.1124/dmd.115.066761 This article has not been copyedited and formatted. The final version may differ from this version. ...
Evolution of Function in Protein Superfamilies, from a Structural
... The recent growth in protein databases has revealed the functional diversity of many protein superfamilies. We have assessed the functional variation of homologous enzyme superfamilies containing two or more enzymes, as de®ned by the CATH protein structure classi®cation, by way of the Enzyme Commiss ...
... The recent growth in protein databases has revealed the functional diversity of many protein superfamilies. We have assessed the functional variation of homologous enzyme superfamilies containing two or more enzymes, as de®ned by the CATH protein structure classi®cation, by way of the Enzyme Commiss ...
FOG-1 - Blood Journal
... negatively regulates the formation of hematopoietic and nonhematopoietic tissues through interactions with GATA proteins. However, the full extent of these interactions, the associated mechanisms, and their functional implications are unknown. Moreover, little is known about the regulation of FOG-1 ...
... negatively regulates the formation of hematopoietic and nonhematopoietic tissues through interactions with GATA proteins. However, the full extent of these interactions, the associated mechanisms, and their functional implications are unknown. Moreover, little is known about the regulation of FOG-1 ...
Transfer of genetic material between the chloroplast and nucleus
... Chloroplast DNA insertions into the Nuclear DNA The completed arabidopsis and rice genome sequences have facilitated the search for evolutionary evidence of the transfer of genes from the original endosymbiont to the nucleus. Proteins encoded by the arabidopsis nuclear genome that are most similar t ...
... Chloroplast DNA insertions into the Nuclear DNA The completed arabidopsis and rice genome sequences have facilitated the search for evolutionary evidence of the transfer of genes from the original endosymbiont to the nucleus. Proteins encoded by the arabidopsis nuclear genome that are most similar t ...
Production of recombinant EMA-1 protein and its
... antibodies anti-T. equi in horses. The ELISA clearly differentiated T. equi-infected from Babesia caballi-infected horse sera or normal horse sera. Field serum samples collected from horses in the State of São Paulo, Southeastern Brazil, were examined for the diagnosis of T. equi infection by ELISA. ...
... antibodies anti-T. equi in horses. The ELISA clearly differentiated T. equi-infected from Babesia caballi-infected horse sera or normal horse sera. Field serum samples collected from horses in the State of São Paulo, Southeastern Brazil, were examined for the diagnosis of T. equi infection by ELISA. ...
The aconitase of Escherichia cok purification of the
... incubated at 37 "C for 5-6 h, overlaid with a nitrocellulose filter and incubated for a further 4-6 h, before fixing (Maniatis et al., 1982). The procedure for immunological detection with nitrocellulose filters from Western blots and plaque lifts was performed at room temperature as described by An ...
... incubated at 37 "C for 5-6 h, overlaid with a nitrocellulose filter and incubated for a further 4-6 h, before fixing (Maniatis et al., 1982). The procedure for immunological detection with nitrocellulose filters from Western blots and plaque lifts was performed at room temperature as described by An ...
Acetate kinase from CIostridiurn acetobutylicurn : a highly specific
... specific activity of 1087 U mg'' (ADP-forming direction). The dimeric enzyme consisted of subunits with a molecular mass of 43 kDa. The molecular mass of the native acetate kinase was in the range 87-94 kDa as judged by gel filtration and native gel electrophoresis. The enzyme showed high specificit ...
... specific activity of 1087 U mg'' (ADP-forming direction). The dimeric enzyme consisted of subunits with a molecular mass of 43 kDa. The molecular mass of the native acetate kinase was in the range 87-94 kDa as judged by gel filtration and native gel electrophoresis. The enzyme showed high specificit ...
Cis-trans peptide variations in structurally similar proteins.
... types VIa1, VIa2 and VIb (that are associated with a cis-Pro (Hutchinson and Thornton 1996)) also dominate the cis conformation. The conformation at the first position (Figure 3A) is represented by β turns VIa1 and VIb with an occurrences of 13.1% and 16.2% respectively. The coil and extended (β str ...
... types VIa1, VIa2 and VIb (that are associated with a cis-Pro (Hutchinson and Thornton 1996)) also dominate the cis conformation. The conformation at the first position (Figure 3A) is represented by β turns VIa1 and VIb with an occurrences of 13.1% and 16.2% respectively. The coil and extended (β str ...
Investigating semantic similarity measures across the
... Clearly, if two proteins are both annotated as “transmembrane receptor”, (GO:0004888) they have a similar semantic description of their function. If one were annotated, less precisely, as just “receptor”, (GO:0004872) then they have a slightly less similar function than before and are correspondingl ...
... Clearly, if two proteins are both annotated as “transmembrane receptor”, (GO:0004888) they have a similar semantic description of their function. If one were annotated, less precisely, as just “receptor”, (GO:0004872) then they have a slightly less similar function than before and are correspondingl ...
Document
... Gene Ontology Annotation @ EBI (GOA) Mouse Genome Database (MGD) and Gene Expression Database (GXD) ...
... Gene Ontology Annotation @ EBI (GOA) Mouse Genome Database (MGD) and Gene Expression Database (GXD) ...
Blamires SJ, Wu CL, Tso IM (2012)
... protein intake regimes: high, low or no protein intake. While the relative genetic inputs into the silks of these species are unknown, species of the former two genera have been reported to exhibit high proline (,9–12%), hence most likely MaSp2 predominant, MA silks [20,21,41,42]. Species from the l ...
... protein intake regimes: high, low or no protein intake. While the relative genetic inputs into the silks of these species are unknown, species of the former two genera have been reported to exhibit high proline (,9–12%), hence most likely MaSp2 predominant, MA silks [20,21,41,42]. Species from the l ...
The CamSol Method of Rational Design of Protein Mutants with
... thousand of mutations to identify those with the greatest impact on the solubility of the target protein while maintaining its native state and biological activity. The application to a single-domain antibody that targets the Alzheimer's Aβ peptide demonstrates that the method predicts with great ac ...
... thousand of mutations to identify those with the greatest impact on the solubility of the target protein while maintaining its native state and biological activity. The application to a single-domain antibody that targets the Alzheimer's Aβ peptide demonstrates that the method predicts with great ac ...
Cloning and Expression of Bovine Sodium/Glucose Cotransporter SGLT2* J. Dairy Sci. 88:2738–2748
... of SGLT2 in the cDNA library of bovine mammary tissues, indicating its expression in bovine mammary gland. To facilitate study of the mechanism of glucose reabsorption in bovine kidneys in maintenance of glucose homeostasis of lactating cows and the potential role of SGLT2 in the mammary gland, we c ...
... of SGLT2 in the cDNA library of bovine mammary tissues, indicating its expression in bovine mammary gland. To facilitate study of the mechanism of glucose reabsorption in bovine kidneys in maintenance of glucose homeostasis of lactating cows and the potential role of SGLT2 in the mammary gland, we c ...
Role of Dietary Soy Protein in Obesity
... 2. Dietary protein and effects on food intake and body weight Ingestion of foods with high protein content is well known to suppress appetite and food intake in humans [14]. Among the three macronutrients (carbohydrate, fat, and protein), protein has the most suppressing effect on food intake. In ad ...
... 2. Dietary protein and effects on food intake and body weight Ingestion of foods with high protein content is well known to suppress appetite and food intake in humans [14]. Among the three macronutrients (carbohydrate, fat, and protein), protein has the most suppressing effect on food intake. In ad ...
Nucleosides, Nucleotides,Nucleic Acids
... This complementary RNA is messenger RNA (mRNA). Mechanism of transcription resembles mechanism of DNA replication. Transcription begins at the 5' end of DNA and is catalyzed by the enzyme RNA polymerase. Dr. Wolf's CHM 424 ...
... This complementary RNA is messenger RNA (mRNA). Mechanism of transcription resembles mechanism of DNA replication. Transcription begins at the 5' end of DNA and is catalyzed by the enzyme RNA polymerase. Dr. Wolf's CHM 424 ...
PPT
... SS Prediction for Transmembrane Proteins Transmembrane (TM) Proteins • Only a few in the PDB - but ~ 30% of cellular proteins are membrane-associated ! • Hard to determine experimentally, so prediction important • TM domains are relatively 'easy' to predict! Why? constraints due to hydrophobic envi ...
... SS Prediction for Transmembrane Proteins Transmembrane (TM) Proteins • Only a few in the PDB - but ~ 30% of cellular proteins are membrane-associated ! • Hard to determine experimentally, so prediction important • TM domains are relatively 'easy' to predict! Why? constraints due to hydrophobic envi ...
Expanded roles of leucine-responsive regulatory protein in
... these two datasets we realized a reverse correlation between amino acid levels and cell growth rate: fast-growing cells contain low-level amino acids, whilst a high level of amino acids exists in slow-growing cells. Taken together, we propose that Lrp is a global regulator of transcription of a larg ...
... these two datasets we realized a reverse correlation between amino acid levels and cell growth rate: fast-growing cells contain low-level amino acids, whilst a high level of amino acids exists in slow-growing cells. Taken together, we propose that Lrp is a global regulator of transcription of a larg ...
William Herdman Elliott 1925–2012
... intensively in later years in Adelaide. He went on to study other systems and this was at the exciting time when the fundamentals of the processes of DNA replication, gene transcription and protein synthesis were rapidly becoming understood. Bill’s publications from this period demonstrate his trans ...
... intensively in later years in Adelaide. He went on to study other systems and this was at the exciting time when the fundamentals of the processes of DNA replication, gene transcription and protein synthesis were rapidly becoming understood. Bill’s publications from this period demonstrate his trans ...
Determination of Optimal Glucose Concentrations
... foreign genes and secretes proteins.’ Glucoamylase (EC 3.2.1.3) which is used to saccharify starchy feed stocks in commercial processes for glucose and ethanol productions, is not produced by S. cerevisiae. With this in mind, the STA gene (glucoamylase gene of Saccharomyces diastaticus) was chosen a ...
... foreign genes and secretes proteins.’ Glucoamylase (EC 3.2.1.3) which is used to saccharify starchy feed stocks in commercial processes for glucose and ethanol productions, is not produced by S. cerevisiae. With this in mind, the STA gene (glucoamylase gene of Saccharomyces diastaticus) was chosen a ...
Analysis of similarity of the S1 gene in infectious bronchitis virus (IBV
... and replicate by means of the specific enveloped transcription. Moreover, its mismatching percent and the combination percent is very high, so the virus can mutate easily (Moore et al 1998). Thus the viruses’ antigenicity and pathogenicity are changed by these factors. Pathogenicity becomes more and ...
... and replicate by means of the specific enveloped transcription. Moreover, its mismatching percent and the combination percent is very high, so the virus can mutate easily (Moore et al 1998). Thus the viruses’ antigenicity and pathogenicity are changed by these factors. Pathogenicity becomes more and ...
Gene Section NOTCH2 (Notch homolog 2 (Drosophila)) Atlas of Genetics and Cytogenetics
... The Notch2 gene is transcribed and translated as a single inactive protein. This protein is cleaved by a furin-like convertase in the trans-golgi network before it reaches the plasma membrane to yield an active form. Cleavage results in a C-terminal fragment and a Nterminal fragment, linked by disul ...
... The Notch2 gene is transcribed and translated as a single inactive protein. This protein is cleaved by a furin-like convertase in the trans-golgi network before it reaches the plasma membrane to yield an active form. Cleavage results in a C-terminal fragment and a Nterminal fragment, linked by disul ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.