An in Silico Liver: Model of Gluconeogenesis
... enzymes regulation. The model also incorporates the compartmentation and intercompartmental transports between the cytosol and the mitochondria, and transport of metabolites between blood compartment and the tissue. The model is based on the experimental set-up of fasted perfused rat livers. The mod ...
... enzymes regulation. The model also incorporates the compartmentation and intercompartmental transports between the cytosol and the mitochondria, and transport of metabolites between blood compartment and the tissue. The model is based on the experimental set-up of fasted perfused rat livers. The mod ...
Ketone Body Metabolism Preserves Hepatic Function during
... neither what lies ahead nor behind does it allow him to see. Eight leagues he traveled and cried out! dense was the darkness, light there was none, neither what lies ahead nor behind does it allow him to see. Nine leagues he traveled... the North Wind. ...
... neither what lies ahead nor behind does it allow him to see. Eight leagues he traveled and cried out! dense was the darkness, light there was none, neither what lies ahead nor behind does it allow him to see. Nine leagues he traveled... the North Wind. ...
- Surrey Research Insight Open Access
... various biomarkers, thought to be correlated with neurotoxin biosynthesis. The objective was to increase our understanding of the metabolism which drives the production of C. botulinum toxin using a Genome-Scale Metabolic Network (GSMN) enhanced surrogate system. A linear correlation was established ...
... various biomarkers, thought to be correlated with neurotoxin biosynthesis. The objective was to increase our understanding of the metabolism which drives the production of C. botulinum toxin using a Genome-Scale Metabolic Network (GSMN) enhanced surrogate system. A linear correlation was established ...
13C MRS: An outstanding tool for metabolic studies
... C label has been incorporated in cerebral metabolites. Indeed, the difference between the intensity of the natural abundance signal and the total intensity of the corresponding multiplet resonance in the spectrum obtained with 13C-labeled substrate reveals the net amount of 13C incorporated in the c ...
... C label has been incorporated in cerebral metabolites. Indeed, the difference between the intensity of the natural abundance signal and the total intensity of the corresponding multiplet resonance in the spectrum obtained with 13C-labeled substrate reveals the net amount of 13C incorporated in the c ...
product monograph - Eli Lilly Canada
... GLUCAGON (glucagon for injection, rDNA origin) is helpful in treating hypoglycemia only if sufficient liver glycogen is present. The patient with type 1 diabetes does not have as great response in blood glucose levels upon administration of glucagon as does the person with stable type 2 diabetes; th ...
... GLUCAGON (glucagon for injection, rDNA origin) is helpful in treating hypoglycemia only if sufficient liver glycogen is present. The patient with type 1 diabetes does not have as great response in blood glucose levels upon administration of glucagon as does the person with stable type 2 diabetes; th ...
Chapter 4 - University of Amsterdam
... long-chain fatty acids from the cytosol to mitochondria as well as the transfer of the products of peroxisomal β-oxidation, i.e. shortened fatty acids and acetyl units to the mitochondria. Additional (related) roles of carnitine include modulation of the acylCoA/CoA ratio, storage of energy (in the ...
... long-chain fatty acids from the cytosol to mitochondria as well as the transfer of the products of peroxisomal β-oxidation, i.e. shortened fatty acids and acetyl units to the mitochondria. Additional (related) roles of carnitine include modulation of the acylCoA/CoA ratio, storage of energy (in the ...
Biology: Concepts and Connections, 6e (Campbell)
... B) have hydrophilic tails that face outward and are exposed to water. C) often have "kinks" in their tails caused by the presence of a double bond between carbons. D) remain fluid because they are tightly packed against one another. E) form impermeable layers for cells . Answer: C Topic: 5.1 Skill: ...
... B) have hydrophilic tails that face outward and are exposed to water. C) often have "kinks" in their tails caused by the presence of a double bond between carbons. D) remain fluid because they are tightly packed against one another. E) form impermeable layers for cells . Answer: C Topic: 5.1 Skill: ...
rapid acting insulin analogues - The Association of Physicians of India
... of absorption necessitates administration of regular human insulin 30 minutes before meals, a practice that many patients do not follow because of its inconvenience. Second, the peak effect of regular insulin may not occur until 3 hours after administration, whereas plasma glucose levels usually ris ...
... of absorption necessitates administration of regular human insulin 30 minutes before meals, a practice that many patients do not follow because of its inconvenience. Second, the peak effect of regular insulin may not occur until 3 hours after administration, whereas plasma glucose levels usually ris ...
Recent Progress in Electrochemical HbA1c Sensors: A Review
... The development of electrochemical glucose sensors is a key subject in the field of biosensors [1–3]. Most glucose sensors consist of metal or carbon electrodes modified with glucose oxidase (GOx), which catalyzes the oxidation of glucose on the surface of the electrode. Recently, much attention has ...
... The development of electrochemical glucose sensors is a key subject in the field of biosensors [1–3]. Most glucose sensors consist of metal or carbon electrodes modified with glucose oxidase (GOx), which catalyzes the oxidation of glucose on the surface of the electrode. Recently, much attention has ...
Unsaturated and Odd-Chain Fatty Acid Catabolism
... The principle pathway for the β-oxidation of fatty acids occurs in the matrix of the mitochondria. There are several other minor pathways that play important physiological roles in fatty acid catabolism. Other organelles can carry out β-oxidation such as the peroxisomes and the glyoxysomes. Peroxiso ...
... The principle pathway for the β-oxidation of fatty acids occurs in the matrix of the mitochondria. There are several other minor pathways that play important physiological roles in fatty acid catabolism. Other organelles can carry out β-oxidation such as the peroxisomes and the glyoxysomes. Peroxiso ...
carboxylesterase 1 plays an essential role in non
... for 20% of the lipid pool in the liver, alteration of de novo synthetic gene expressions are often present in patients with metabolic diseases. Hyperinsulinemia and hyperglycemia induce sterol regulatory element-binding protein 1c (SREBP-1c) and carbohydrate response element binding protein (ChREBP) ...
... for 20% of the lipid pool in the liver, alteration of de novo synthetic gene expressions are often present in patients with metabolic diseases. Hyperinsulinemia and hyperglycemia induce sterol regulatory element-binding protein 1c (SREBP-1c) and carbohydrate response element binding protein (ChREBP) ...
respiration
... Results and discussion At the end of the experiment, the liquid level in arm A rises and the liquid level in arm B falls. This is because the mouse releases heat which warms up the air in the test tube on the side where it is. The expansion of air inside the tube increases the pressure. This causes ...
... Results and discussion At the end of the experiment, the liquid level in arm A rises and the liquid level in arm B falls. This is because the mouse releases heat which warms up the air in the test tube on the side where it is. The expansion of air inside the tube increases the pressure. This causes ...
Saccharomyces species in the Production of Beer
... brewing will be discussed in Section 8. Yeast is cultured in an acidic aqueous sugary solution called wort prepared from barley malt and other cereals such as corn (maize), wheat, rice, sorghum, and also cane and beet sugar. The cells absorb dissolved sugars, simple nitrogenous matter (amino acids, ...
... brewing will be discussed in Section 8. Yeast is cultured in an acidic aqueous sugary solution called wort prepared from barley malt and other cereals such as corn (maize), wheat, rice, sorghum, and also cane and beet sugar. The cells absorb dissolved sugars, simple nitrogenous matter (amino acids, ...
Sucrose breakdown in the potato tuber - publish.UP
... In this work different approaches are undertaken to improve the understanding of the sucroseto-starch pathway in developing potato tubers. At first an inducible gene expression system from fungal origin is optimised for the use of studying metabolism in the potato tuber. It is found that the alc sys ...
... In this work different approaches are undertaken to improve the understanding of the sucroseto-starch pathway in developing potato tubers. At first an inducible gene expression system from fungal origin is optimised for the use of studying metabolism in the potato tuber. It is found that the alc sys ...
Propionate stimulates pyruvate oxidation in the - AJP
... Isotopes (Andover, MA). Trityl-OXO63 free radical was purchased from Oxford Instruments Molecular Biotools (Oxford, UK). Protocol. The protocol was approved by the Institutional Animal Care and Use Committee of the University of Texas Southwestern Medical Center. Female mice, 14 –16 wk in age, were ...
... Isotopes (Andover, MA). Trityl-OXO63 free radical was purchased from Oxford Instruments Molecular Biotools (Oxford, UK). Protocol. The protocol was approved by the Institutional Animal Care and Use Committee of the University of Texas Southwestern Medical Center. Female mice, 14 –16 wk in age, were ...
Energy and Muscle Contraction
... Therefore, during this time, cellular respiration will be going at capacity, limited only by oxygen restraints. Glycolysis, on the other hand, will proceed at an accelerated rate for the purpose of gaining extra ATP. Note that during this time, pyruvate will be fed into the mitochondria as fast as s ...
... Therefore, during this time, cellular respiration will be going at capacity, limited only by oxygen restraints. Glycolysis, on the other hand, will proceed at an accelerated rate for the purpose of gaining extra ATP. Note that during this time, pyruvate will be fed into the mitochondria as fast as s ...
Malic acid production by Aspergillus oryzae
... from the mitochondrion in the cytosol, the whole process seems more like a bioconversion of glucose to citrate with maximum yields of about 95%. The above described pathway shows the origin of pyruvate as a direct result of glycolysis. But it was shown that considerable amounts of citric acid must h ...
... from the mitochondrion in the cytosol, the whole process seems more like a bioconversion of glucose to citrate with maximum yields of about 95%. The above described pathway shows the origin of pyruvate as a direct result of glycolysis. But it was shown that considerable amounts of citric acid must h ...
chapter 15: answers to selected problems
... 15.20 In an activation reaction, a cell uses energy from ATP to build a high-energy molecule (usually a compound that contains a phosphate group attached to an organic fragment). The ATP breaks down into ADP and phosphate. 15.21 In glycolysis, glucose is broken down into two pyruvate ions. 15.22 Lac ...
... 15.20 In an activation reaction, a cell uses energy from ATP to build a high-energy molecule (usually a compound that contains a phosphate group attached to an organic fragment). The ATP breaks down into ADP and phosphate. 15.21 In glycolysis, glucose is broken down into two pyruvate ions. 15.22 Lac ...
Biology: Concepts and Connections, 6e (Campbell)
... B) have hydrophilic tails that face outward and are exposed to water. C) often have "kinks" in their tails caused by the presence of a double bond between carbons. D) remain fluid because they are tightly packed against one another. E) form impermeable layers for cells . Answer: C Topic: 5.1 Skill: ...
... B) have hydrophilic tails that face outward and are exposed to water. C) often have "kinks" in their tails caused by the presence of a double bond between carbons. D) remain fluid because they are tightly packed against one another. E) form impermeable layers for cells . Answer: C Topic: 5.1 Skill: ...
Full-Text PDF
... Therefore, we will delineate fructose-induced tissue and organ dysfunctions resulting from these direct and/or indirect dangerous factors. It will focus on the correlations between different metabolites and functional assignment of different tissues and organs in the whole body under high fructose c ...
... Therefore, we will delineate fructose-induced tissue and organ dysfunctions resulting from these direct and/or indirect dangerous factors. It will focus on the correlations between different metabolites and functional assignment of different tissues and organs in the whole body under high fructose c ...
Boundless Study Slides
... • acetyl CoA a molecule that conveys the carbon atoms from glycolysis (pyruvate) to the citric acid cycle to be oxidized for energy production • adenosine triphosphate a multifunctional nucleoside triphosphate used in cells as a coenzyme, often called the "molecular unit of energy currency" in intra ...
... • acetyl CoA a molecule that conveys the carbon atoms from glycolysis (pyruvate) to the citric acid cycle to be oxidized for energy production • adenosine triphosphate a multifunctional nucleoside triphosphate used in cells as a coenzyme, often called the "molecular unit of energy currency" in intra ...
Fructose, Glucocorticoids and Adipose Tissue: Implications for the
... to anaerobic glycolysis and increases the secretion of a number of inflammation-related adipokines accompanied with cell damage [9]. On the other hand, this inflammatory response is also a key factor for modulating insulin sensitivity in adipose tissue and the development of obesity-associated disea ...
... to anaerobic glycolysis and increases the secretion of a number of inflammation-related adipokines accompanied with cell damage [9]. On the other hand, this inflammatory response is also a key factor for modulating insulin sensitivity in adipose tissue and the development of obesity-associated disea ...
Chapter 4 General metabolism
... to a series of oxidation-reduction reactions and may originate by fermentation products such as ethanol, lactic acid, CO2, or be channeled into Krebs cycle for respiration. The intracellular hexoses enter the glycolytic pathway after a phosphorylation step, which in the case of glucose leads to gluc ...
... to a series of oxidation-reduction reactions and may originate by fermentation products such as ethanol, lactic acid, CO2, or be channeled into Krebs cycle for respiration. The intracellular hexoses enter the glycolytic pathway after a phosphorylation step, which in the case of glucose leads to gluc ...
Acetyl CoA - WordPress.com
... NADH is re-oxidized in the electron transport pathway, making ATP in oxidative phosphorylation ...
... NADH is re-oxidized in the electron transport pathway, making ATP in oxidative phosphorylation ...
Glucose
Glucose is a sugar with the molecular formula C6H12O6. The name ""glucose"" (/ˈɡluːkoʊs/) comes from the Greek word γλευκος, meaning ""sweet wine, must"". The suffix ""-ose"" is a chemical classifier, denoting a carbohydrate. It is also known as dextrose or grape sugar. With 6 carbon atoms, it is classed as a hexose, a sub-category of monosaccharides. α-D-glucose is one of the 16 aldose stereoisomers. The D-isomer (D-glucose) occurs widely in nature, but the L-isomer (L-glucose) does not. Glucose is made during photosynthesis from water and carbon dioxide, using energy from sunlight. The reverse of the photosynthesis reaction, which releases this energy, is a very important source of power for cellular respiration. Glucose is stored as a polymer, in plants as starch and in animals as glycogen.