Fatigue During Muscular Exercise
... • Two hypothesis for peripheral fatigue • a) Exhaustion - depletion of energy substrates - eg ATP, CP, glycogen – Phosphagens are present in low quantities – Must match use with restoration from other metabolic pathways - or fatigue ...
... • Two hypothesis for peripheral fatigue • a) Exhaustion - depletion of energy substrates - eg ATP, CP, glycogen – Phosphagens are present in low quantities – Must match use with restoration from other metabolic pathways - or fatigue ...
(1) Giycophorin was incorporated into large
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
... suits of these experiments are summarized in Table I. Comparison of the permeability data of the glycophorin-containing vesicles with the pure lipid vesicles, clearly shows that incorporation of glycophorin induces a largely increased permeability for glucose as well as for raffinose. This confirms ...
AMP-activated protein kinase and metabolic control - HAL
... AMPK is a major regulator of cellular and whole-body energy homeostasis that coordinates metabolic pathways in order to balance nutrient supply with energy demand. Activation of AMPK switches off ATP-consuming anabolic pathways and switches on ATPproducing catabolic pathways (Viollet et al. 2003). T ...
... AMPK is a major regulator of cellular and whole-body energy homeostasis that coordinates metabolic pathways in order to balance nutrient supply with energy demand. Activation of AMPK switches off ATP-consuming anabolic pathways and switches on ATPproducing catabolic pathways (Viollet et al. 2003). T ...
Nature template
... phenylalanine (Phe), valine (Val) and in fatty acids indicate that 13C-label is only present in C-1 of phosphoglyceric acid (PGA), while C-2 and C-3 are almost unlabeled. If CO2 is fixed via the cyclic reductive pentose phosphate pathway (Calvin cycle), label would be distributed among all three car ...
... phenylalanine (Phe), valine (Val) and in fatty acids indicate that 13C-label is only present in C-1 of phosphoglyceric acid (PGA), while C-2 and C-3 are almost unlabeled. If CO2 is fixed via the cyclic reductive pentose phosphate pathway (Calvin cycle), label would be distributed among all three car ...
Glucosamine-Induced Insulin Resistance in Primary Rat
... insulin and glucagon during fed and fasting states (Flakoll PJ 2000). Insulin, a hormone secreted by the P- cells of the islets of Langerhans in the pancreas, plays an important role in maintaining glucose homeostasis and is secreted in response to elevated blood glucose. Glucagon, a hormone secrete ...
... insulin and glucagon during fed and fasting states (Flakoll PJ 2000). Insulin, a hormone secreted by the P- cells of the islets of Langerhans in the pancreas, plays an important role in maintaining glucose homeostasis and is secreted in response to elevated blood glucose. Glucagon, a hormone secrete ...
Cellular respiration
... Glucose breakdown starts with glycolysis, that occurs in the cytoplasm and is an anaerobic process. Pyruvate is the final product of the glycolysis and it can follow two pathways: 1.Cellular respiration (aerobic pathway) 1.Fermentation (anaerobic pathway) ...
... Glucose breakdown starts with glycolysis, that occurs in the cytoplasm and is an anaerobic process. Pyruvate is the final product of the glycolysis and it can follow two pathways: 1.Cellular respiration (aerobic pathway) 1.Fermentation (anaerobic pathway) ...
Cellular respiration
... Glucose breakdown starts with glycolysis, that occurs in the cytoplasm and is an anaerobic process. Pyruvate is the final product of the glycolysis and it can follow two pathways: 1.Cellular respiration (aerobic pathway) 1.Fermentation (anaerobic pathway) ...
... Glucose breakdown starts with glycolysis, that occurs in the cytoplasm and is an anaerobic process. Pyruvate is the final product of the glycolysis and it can follow two pathways: 1.Cellular respiration (aerobic pathway) 1.Fermentation (anaerobic pathway) ...
추가8
... The phenomenon, in which glucose represses aerobic metabolism, is the Crabtree effect Rapid production of ethanol has the effect of eliminating microbial competitors Once glucose levels are depleted and O2 is available the yeast reabsorbs the ethanol and converts it to acetaldehyde for use as an ...
... The phenomenon, in which glucose represses aerobic metabolism, is the Crabtree effect Rapid production of ethanol has the effect of eliminating microbial competitors Once glucose levels are depleted and O2 is available the yeast reabsorbs the ethanol and converts it to acetaldehyde for use as an ...
insulin therapy for children and adolescents with type 1 diabetes
... Insulin aspart (Novolog®) Substitution of proline by aspartic acid on position 28 of chain B. Similar pharmacokinetics to lispro. Better PPG control and less nocturnal hypoglycemia. Insulin glulisine (Apidra®) • Substitution of asparagine by lysine on position 28 and lysine by glutamic acid ...
... Insulin aspart (Novolog®) Substitution of proline by aspartic acid on position 28 of chain B. Similar pharmacokinetics to lispro. Better PPG control and less nocturnal hypoglycemia. Insulin glulisine (Apidra®) • Substitution of asparagine by lysine on position 28 and lysine by glutamic acid ...
Electrolytes and metabolic disorder.
... Such relationships should not be interpreted as cause and effect ...
... Such relationships should not be interpreted as cause and effect ...
Pharmaceutical Care in PET Imaging: Emphasis on [ F]FDG Imaging
... within the tissues. The degree of entrapment is proportional to the rate of glycolysis or glucose metabolism of the tissue. Because glucose is hydrophilic, entry into cells is not by simple diffusion. Transport of glucose, and therefore, FDG transport, from the blood to the tissues is regulated by t ...
... within the tissues. The degree of entrapment is proportional to the rate of glycolysis or glucose metabolism of the tissue. Because glucose is hydrophilic, entry into cells is not by simple diffusion. Transport of glucose, and therefore, FDG transport, from the blood to the tissues is regulated by t ...
Module 1. General principles of metabolism. Metabolism of
... D. The doctor has given up on the patient and administers ethanol for sedation E. B and C 91. If it is known that the only two ionizable residues in the active site are both glutamates, which conclusion can be drawn? A. * The glutamates have different microenviroments which cause their pKa's to diff ...
... D. The doctor has given up on the patient and administers ethanol for sedation E. B and C 91. If it is known that the only two ionizable residues in the active site are both glutamates, which conclusion can be drawn? A. * The glutamates have different microenviroments which cause their pKa's to diff ...
- Wiley Online Library
... 55, 680–685]. Strain CCTCC M202019 produced 21% higher pyruvate than the parent strain and was genetically stable in flask cultures. The activities of the pyruvate metabolism-related enzymes in parent and mutant strains were measured. Compared with the parent strain, the activity of pyruvate decarbo ...
... 55, 680–685]. Strain CCTCC M202019 produced 21% higher pyruvate than the parent strain and was genetically stable in flask cultures. The activities of the pyruvate metabolism-related enzymes in parent and mutant strains were measured. Compared with the parent strain, the activity of pyruvate decarbo ...
Owens et al., 1998, Acidosis in cattle: a review.
... Meal frequency may be as important as total feed intake as a cause of acidosis. For example, cattle with implants typically have greater feed intakes. Weather changes and processing cattle to provide implants or inoculations often disrupt feeding patterns and may result in overconsumption and acidos ...
... Meal frequency may be as important as total feed intake as a cause of acidosis. For example, cattle with implants typically have greater feed intakes. Weather changes and processing cattle to provide implants or inoculations often disrupt feeding patterns and may result in overconsumption and acidos ...
Module 2 General principles of metabolism. Мetabolism of carbohy
... D. None of the above E. Ten substrates 54. The result of a(n) __________ reaction is that energy is released. Energy must be added for a(n) __________ reaction to proceed. A. Enzyme catalyzed, non-spontaneous B. * Exergonic, endergonic C. Endergonic, spontaneous D. Catalytic, non-catalytic E. Oxidat ...
... D. None of the above E. Ten substrates 54. The result of a(n) __________ reaction is that energy is released. Energy must be added for a(n) __________ reaction to proceed. A. Enzyme catalyzed, non-spontaneous B. * Exergonic, endergonic C. Endergonic, spontaneous D. Catalytic, non-catalytic E. Oxidat ...
Carnitine Acetyltransferase and Mitochondrial Acetyl
... regulator of enzymatic activity. Supporting this hypothesis, an estimated 35% of mitochondrial proteins have been shown to be acetylated, the majority of which are involved in energy metabolism (Anderson and Hirschey 2012). Moreover, greater than 50% of these proteins are involved in glucose, fatty ...
... regulator of enzymatic activity. Supporting this hypothesis, an estimated 35% of mitochondrial proteins have been shown to be acetylated, the majority of which are involved in energy metabolism (Anderson and Hirschey 2012). Moreover, greater than 50% of these proteins are involved in glucose, fatty ...
Glycolytic strategy as a tradeoff between energy yield and protein cost
... diverse, including several alternative glycolytic pathways, the most common of which is the Entner–Doudoroff (ED) pathway. The prevalence of the ED pathway is puzzling as it produces only one ATP per glucose—half as much as the EMP pathway. We argue that the diversity of prokaryotic glucose metaboli ...
... diverse, including several alternative glycolytic pathways, the most common of which is the Entner–Doudoroff (ED) pathway. The prevalence of the ED pathway is puzzling as it produces only one ATP per glucose—half as much as the EMP pathway. We argue that the diversity of prokaryotic glucose metaboli ...
Formatted - RESPIRATION
... The conversion of pyruvate into acetyl coenzyme A comprises following steps : 1. Pyruvate combines with the cofactor TPP (thymine pyrophosphate) and loses CO2. The reaction is catalysed by pyruvate dehydrogenase component (called E1) of the multi-enzyme complex. ...
... The conversion of pyruvate into acetyl coenzyme A comprises following steps : 1. Pyruvate combines with the cofactor TPP (thymine pyrophosphate) and loses CO2. The reaction is catalysed by pyruvate dehydrogenase component (called E1) of the multi-enzyme complex. ...
The Maillard Reaction
... I Initial stage: products colourless, without absorption in the ultraviolet (about ...
... I Initial stage: products colourless, without absorption in the ultraviolet (about ...
Muscle alanine synthesis and hepatic gluconeogenesis
... of the amino acid nitrogen towards alanine formation would serve to prevent excessive generation of potentially toxic ammonia by the purine nucleotide cycle. The precise roles of amino acid breakdown and ammonia generation in muscle are not clear, but it may be that one function of ammonia formation ...
... of the amino acid nitrogen towards alanine formation would serve to prevent excessive generation of potentially toxic ammonia by the purine nucleotide cycle. The precise roles of amino acid breakdown and ammonia generation in muscle are not clear, but it may be that one function of ammonia formation ...
The malonyl CoA axis as a potential target for treating ischaemic
... to the suggestion that the malonyl CoA produced by this isoform is more involved in the regulation of fatty acid oxidation, as opposed to the high abundance of ACCa in the liver, where the malonyl CoA produced by this isoform is more involved in the regulation of fatty acid synthesis. Studies from o ...
... to the suggestion that the malonyl CoA produced by this isoform is more involved in the regulation of fatty acid oxidation, as opposed to the high abundance of ACCa in the liver, where the malonyl CoA produced by this isoform is more involved in the regulation of fatty acid synthesis. Studies from o ...
A PEST-like Sequence in the N-Terminal Cytoplasmic Domain of
... loss of transport activity, characterized by an initial very rapid inactivation of maltose transport activity followed by a slower loss in transport activity that correlates with the degradation of maltose permease protein (3). This degradation is dependent on endocytosis, vesicle sorting, and the v ...
... loss of transport activity, characterized by an initial very rapid inactivation of maltose transport activity followed by a slower loss in transport activity that correlates with the degradation of maltose permease protein (3). This degradation is dependent on endocytosis, vesicle sorting, and the v ...
Involvement of Polyamine Catabolism in the Regulation of Glucose
... regulation of glucose, energy and lipid metabolism was investigated using transgenic mice overexpressing or deficient for SSAT. The characterization of SSAT mice revealed that these mice exhibited severely reduced whole body WAT mass, elevated energy expenditure, high insulin sensitivity, a low tiss ...
... regulation of glucose, energy and lipid metabolism was investigated using transgenic mice overexpressing or deficient for SSAT. The characterization of SSAT mice revealed that these mice exhibited severely reduced whole body WAT mass, elevated energy expenditure, high insulin sensitivity, a low tiss ...
Glucose
Glucose is a sugar with the molecular formula C6H12O6. The name ""glucose"" (/ˈɡluːkoʊs/) comes from the Greek word γλευκος, meaning ""sweet wine, must"". The suffix ""-ose"" is a chemical classifier, denoting a carbohydrate. It is also known as dextrose or grape sugar. With 6 carbon atoms, it is classed as a hexose, a sub-category of monosaccharides. α-D-glucose is one of the 16 aldose stereoisomers. The D-isomer (D-glucose) occurs widely in nature, but the L-isomer (L-glucose) does not. Glucose is made during photosynthesis from water and carbon dioxide, using energy from sunlight. The reverse of the photosynthesis reaction, which releases this energy, is a very important source of power for cellular respiration. Glucose is stored as a polymer, in plants as starch and in animals as glycogen.